@article{MTMT:34135659,
	title = {High Salt Promotes Inflammatory and Fibrotic Response in Peritoneal Cells},
	url = {https://m2.mtmt.hu/api/publication/34135659},
	author = {Pap, Domonkos and Pajtók, Csenge and Veres-Székely, Apor and Szebeni, Beáta and Szász, Csenge and Bokrossy, Péter and Zrufkó, Réka and Vannay, Ádám and Tulassay, Tivadar and Szabó, Attila},
	doi = {10.3390/ijms241813765},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {24},
	unique-id = {34135659},
	issn = {1661-6596},
	abstract = {Recent studies draw attention to how excessive salt (NaCl) intake induces fibrotic alterations in the peritoneum through sodium accumulation and osmotic events. The aim of our study was to better understand the underlying mechanisms. The effects of additional NaCl were investigated on human primary mesothelial cells (HPMC), human primary peritoneal fibroblasts (HPF), endothelial cells (HUVEC), immune cells (PBMC), as well as ex vivo on peritoneal tissue samples. Our results showed that a high-salt environment and the consequently increased osmolarity increase the production of inflammatory cytokines, profibrotic growth factors, and components of the renin–angiotensin–aldosterone system, including IL1B, IL6, MCP1, TGFB1, PDGFB, CTGF, Renin and Ace both in vitro and ex vivo. We also demonstrated that high salt induces mesenchymal transition by decreasing the expression of epithelial marker CDH1 and increasing the expression of mesenchymal marker ACTA2 and SNAIL1 in HPMCs, HUVECs and peritoneal samples. Furthermore, high salt increased extracellular matrix production in HPFs. We demonstrated that excess Na+ and the consequently increased osmolarity induce a comprehensive profibrotic response in the peritoneal cells, thereby facilitating the development of peritoneal fibrosis.},
	year = {2023},
	eissn = {1422-0067},
	orcid-numbers = {Pap, Domonkos/0000-0002-1718-1210; Veres-Székely, Apor/0000-0002-6830-8779; Szebeni, Beáta/0000-0001-7577-9803; Vannay, Ádám/0000-0001-7412-4733; Tulassay, Tivadar/0000-0002-5387-8103; Szabó, Attila/0000-0001-7321-9861}
}

@article{MTMT:33028317,
	title = {Comparative evaluation of approach to cardiovascular care in neonatal encephalopathy undergoing therapeutic hypothermia},
	url = {https://m2.mtmt.hu/api/publication/33028317},
	author = {Kovács, Kata and Giesinger, Regan E. and Lakatos, Andrea and Szabó, Attila and Szabó, Miklós and Jermendy, Ágnes and McNamara, Patrick J.},
	doi = {10.1038/s41372-022-01459-6},
	journal-iso = {J PERINATOL},
	journal = {JOURNAL OF PERINATOLOGY},
	volume = {42},
	unique-id = {33028317},
	issn = {0743-8346},
	year = {2022},
	eissn = {1476-5543},
	pages = {1637-1643},
	orcid-numbers = {Kovács, Kata/0000-0002-7115-6147; Giesinger, Regan E./0000-0002-6227-6761; Szabó, Attila/0000-0001-7321-9861; Szabó, Miklós/0000-0003-3317-5619; Jermendy, Ágnes/0000-0002-2211-7272; McNamara, Patrick J./0000-0001-7648-8872}
}

@article{MTMT:33023411,
	title = {A retrospective analysis of metabolic control in children with PKU in the COVID-19 era},
	url = {https://m2.mtmt.hu/api/publication/33023411},
	author = {Becsei, Dóra and Kiss, Erika and Szatmári, Ildikó and Arató, András and Reusz, György and Szabó, Attila and Bókay, János and Zsidegh, Petra},
	doi = {10.1016/j.ymgmr.2022.100897},
	journal-iso = {MOL GENET METAB REP},
	journal = {MOLECULAR GENETICS AND METABOLISM REPORTS},
	volume = {32},
	unique-id = {33023411},
	year = {2022},
	eissn = {2214-4269},
	orcid-numbers = {Becsei, Dóra/0000-0001-8031-4453; Kiss, Erika/0000-0002-7465-2728; Szatmári, Ildikó/0000-0003-1040-145X; Arató, András/0000-0002-7980-6327; Reusz, György/0000-0003-0396-043X; Szabó, Attila/0000-0001-7321-9861; Bókay, János/0000-0001-7552-9169; Zsidegh, Petra/0000-0003-2931-2633}
}

@article{MTMT:33002115,
	title = {A fibroblastok funkcionális vizsgálata – II. rész: Sejtmigrációs mérések},
	url = {https://m2.mtmt.hu/api/publication/33002115},
	author = {Sepsi, Zita and Bokrossy, Péter and Szász, Csenge and Pap, Domonkos and Szebeni, Beáta and Szabó, Attila and Vannay, Ádám and Veres-Székely, Apor},
	journal-iso = {GYERMEKGYÓGYÁSZAT},
	journal = {GYERMEKGYÓGYÁSZAT},
	volume = {73},
	unique-id = {33002115},
	issn = {0017-5900},
	year = {2022},
	pages = {252-254},
	orcid-numbers = {Pap, Domonkos/0000-0002-1718-1210; Szebeni, Beáta/0000-0001-7577-9803; Szabó, Attila/0000-0001-7321-9861; Vannay, Ádám/0000-0001-7412-4733; Veres-Székely, Apor/0000-0002-6830-8779}
}

@article{MTMT:32962031,
	title = {Longitudinal Analysis of Amplitude-Integrated Electroencephalography for Outcome Prediction in Hypoxic-Ischemic Encephalopathy},
	url = {https://m2.mtmt.hu/api/publication/32962031},
	author = {Méder, Ünőke and Csekő, Anna Judit and Szakacs, Laszlo and Balogh, Dóra Csenge and Szakmár, Enikő and Andorka, Csilla and Kovács, Kata and Dobi, Marianna and Brandt, Ferenc and Szabó, Miklós and Szabó, Attila and Jermendy, Ágnes},
	doi = {10.1016/j.jpeds.2022.04.013},
	journal-iso = {J PEDIATR},
	journal = {JOURNAL OF PEDIATRICS},
	volume = {246},
	unique-id = {32962031},
	issn = {0022-3476},
	abstract = {Objective To investigate the prognostic accuracy of longitudinal analysis of amplitude-integrated electroencephalography (aEEG) background activity to predict long-term neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy (HIE) receiving therapeutic hypothermia.Study design This single-center observational study included 149 neonates for derivation and 55 neonates for validation with moderate-severe HIE and of gestational age 35 weeks at a tertiary neonatal intensive care unit. Single-channel aEEG background pattern, sleep-wake cycling, and seizure activity were monitored over 84 hours during therapeutic hypothermia and rewarming, then scored for each 6-hour interval. Neurodevelopmental outcome was assessed using the Bayley Scales of Infant Development, Second Edition. Favorable outcome was defined as having both a Mental Development Index (MDI) score and Psychomotor Development Index (PDI) score >= 70, and adverse outcome was defined as either an MDI or a PDI <70 or death. Regression modeling for longitudinal analysis of repeatedly measured data was applied, and area under the receiver operating characteristic curve (AUC) was calculated.Resuits Longitudinal aEEG background analysis combined with sleep-wake cycling score had excellent predictive value (AUC, 0.90; 95% CI, 0.85-0.95), better than single aEEG scores at any individual time point. The model performed well in the independent validation cohort (AUC, 0.87; 95% CI, 0.62-1.00). The reclassification rate of this model compared with the conventional analysis of aEEG background at 48 hours was 18% (24 patients); 14% (18 patients) were reclassified correctly. Our results were used to develop a user-friendly online outcome prediction tool.Conclusions Longitudinal analysis of aEEG background activity and sleep-wake cycling is a valuable and accurate prognostic tool.},
	year = {2022},
	eissn = {1097-6833},
	pages = {19-25.e5},
	orcid-numbers = {Méder, Ünőke/0000-0001-5323-3156; Csekő, Anna Judit/0000-0001-6071-1822; Szakmár, Enikő/0000-0002-8848-8092; Andorka, Csilla/0000-0002-9714-1111; Kovács, Kata/0000-0002-7115-6147; Brandt, Ferenc/0000-0003-2808-8596; Szabó, Miklós/0000-0003-3317-5619; Szabó, Attila/0000-0001-7321-9861; Jermendy, Ágnes/0000-0002-2211-7272}
}

@misc{MTMT:32925862,
	title = {Perinatalis aszfixiát követő többszervi károsodás patkány modellben},
	url = {https://m2.mtmt.hu/api/publication/32925862},
	author = {Lakat, Tamás and Hosszú, Ádám and Tóth, Ákos Roland and Molnár, Ágnes and Varga, Zoltán Kristóf and Kelemen, Hanga and Szabó, Attila and Szabó, Miklós and Fekete, Andrea},
	unique-id = {32925862},
	year = {2022},
	orcid-numbers = {Lakat, Tamás/0000-0001-9769-3728; Hosszú, Ádám/0000-0002-8415-5637; Tóth, Ákos Roland/0000-0002-2516-0508; Molnár, Ágnes/0000-0002-8783-2752; Szabó, Attila/0000-0001-7321-9861; Szabó, Miklós/0000-0003-3317-5619; Fekete, Andrea/0000-0002-0210-153X}
}

@article{MTMT:32925822,
	title = {Új terápiás lehetőségek az akut vesekárosodás kezelésében},
	url = {https://m2.mtmt.hu/api/publication/32925822},
	author = {Pap, Domonkos and Pajtók, Csenge and Veres-Székely, Apor and Szebeni, Beáta and Lévai, Eszter and Reusz, György and Szabó, Attila and Vannay, Ádám},
	journal-iso = {HYPERTONIA NEPHROLOGIA},
	journal = {HYPERTONIA ÉS NEPHROLOGIA},
	volume = {26},
	unique-id = {32925822},
	issn = {1418-477X},
	year = {2022},
	eissn = {2498-6259},
	pages = {41-42},
	orcid-numbers = {Pap, Domonkos/0000-0002-1718-1210; Veres-Székely, Apor/0000-0002-6830-8779; Szebeni, Beáta/0000-0001-7577-9803; Lévai, Eszter/0000-0002-6149-3254; Reusz, György/0000-0003-0396-043X; Szabó, Attila/0000-0001-7321-9861; Vannay, Ádám/0000-0001-7412-4733}
}

@article{MTMT:32925798,
	title = {A PARK7 szerepe a peritonealis dialízis-asszociált fibrózisban},
	url = {https://m2.mtmt.hu/api/publication/32925798},
	author = {Veres-Székely, Apor and Lévai, Eszter and Szebeni, Beáta and Szász, Csenge and Pap, Domonkos and Pajtók, Csenge and Reusz, György and Szabó, Attila and Vannay, Ádám},
	journal-iso = {HYPERTONIA NEPHROLOGIA},
	journal = {HYPERTONIA ÉS NEPHROLOGIA},
	volume = {26},
	unique-id = {32925798},
	issn = {1418-477X},
	year = {2022},
	eissn = {2498-6259},
	pages = {46-47},
	orcid-numbers = {Veres-Székely, Apor/0000-0002-6830-8779; Lévai, Eszter/0000-0002-6149-3254; Szebeni, Beáta/0000-0001-7577-9803; Pap, Domonkos/0000-0002-1718-1210; Reusz, György/0000-0003-0396-043X; Szabó, Attila/0000-0001-7321-9861; Vannay, Ádám/0000-0001-7412-4733}
}

@article{MTMT:32925740,
	title = {Extracelluláris vezikulák (EV) szerepe a peritonealis fibrózis kialakulásában},
	url = {https://m2.mtmt.hu/api/publication/32925740},
	author = {Szebeni, Beáta and Varga, Zoltán and Takács, István Márton and Pállinger, Éva and Pap, Domonkos and Veres-Székely, Apor and Szabó, Attila and Reusz, György and Vannay, Ádám},
	journal-iso = {HYPERTONIA NEPHROLOGIA},
	journal = {HYPERTONIA ÉS NEPHROLOGIA},
	volume = {26},
	unique-id = {32925740},
	issn = {1418-477X},
	year = {2022},
	eissn = {2498-6259},
	pages = {45-45},
	orcid-numbers = {Szebeni, Beáta/0000-0001-7577-9803; Pap, Domonkos/0000-0002-1718-1210; Veres-Székely, Apor/0000-0002-6830-8779; Szabó, Attila/0000-0001-7321-9861; Reusz, György/0000-0003-0396-043X; Vannay, Ádám/0000-0001-7412-4733}
}

@CONFERENCE{MTMT:32924364,
	title = {The protective role of fluvoxamine in fibrotic disorders of the eye},
	url = {https://m2.mtmt.hu/api/publication/32924364},
	author = {Tran, Ngoc Minh and Besztercei, Balázs and Torok, Gyorgy and Medveczki, Tímea and Kovács, Illés and Szabó, Attila and Fekete, Andrea and Hodrea, Judit},
	booktitle = {15th EGS Congress},
	unique-id = {32924364},
	year = {2022},
	pages = {44-44},
	orcid-numbers = {Tran, Ngoc Minh/0000-0002-6925-0871; Medveczki, Tímea/0000-0002-3618-6690; Kovács, Illés/0000-0001-5763-0482; Szabó, Attila/0000-0001-7321-9861; Fekete, Andrea/0000-0002-0210-153X; Hodrea, Judit/0000-0002-6388-4021}
}