@article{MTMT:34849915,
	title = {Epileptiform discharges in the anterior thalamus of epilepsy patients.},
	url = {https://m2.mtmt.hu/api/publication/34849915},
	author = {Jordán, Zsófia and Szabó, Johanna Petra and Sákovics, Anna and Kelemen, Anna and Halász, László and Erőss, Loránd and Fabó, Dániel},
	doi = {10.1016/j.isci.2024.109582},
	journal-iso = {ISCIENCE},
	journal = {ISCIENCE},
	volume = {27},
	unique-id = {34849915},
	abstract = {Anterior thalamus (ANT) deep-brain stimulation (DBS) is an approved therapy for drug resistant epilepsy. We aimed to identify interictal epileptiform discharges (IED) in the ANT and to investigate their relationship with surface IEDs. Fifteen patients were monitored for two consecutive nights with externalized thalamic leads to analyze the intrathalamic epileptiform activities (TIED). Forty-six % of all contacts were located within the ANT. We found that all the responders had TIEDs within the ANT, while this held true only for 44% of the non-responders. The overall response rate (RR) at 1-year follow-up was 40%, while it was 44% in bilateral ANT hit patients and 45% in epileptic focus side hit. However, in case of TIEDs present in the focus side the RR reached as high as 71%. TIED activity may prove the pathophysiological connection to the seizure focus, and stimulation of this area might have a better suppressing effect on seizures.},
	keywords = {Health sciences; medical tests; clinical finding},
	year = {2024},
	eissn = {2589-0042},
	orcid-numbers = {Szabó, Johanna Petra/0000-0001-7690-9171; Kelemen, Anna/0000-0003-3942-3409; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:34714085,
	title = {Grading system for assessing the confidence in the epileptogenic zone reported in published studies. A Delphi consensus study},
	url = {https://m2.mtmt.hu/api/publication/34714085},
	author = {Ryvlin, Philippe and Barba, Carmen and Bartolomei, Fabrice and Baumgartner, Christoph and Brazdil, Milan and Fabó, Dániel and Fahoum, Firas and Frauscher, Birgit and Ikeda, Akio and Lhatoo, Samden and Mani, Jayanti and McGonigal, Aileen and Metsahonkala, Eeva-Liisa and Mindruta, Ioana and Nguyen, Dang Khoa and Rheims, Sylvain and Rocamora, Rodrigo and Rydenhag, Bertil and Schuele, Stephan and Schulze-Bonhage, Andreas and Surges, Rainer and Vulliemoz, Serge and Beniczky, Sándor},
	doi = {10.1111/epi.17928},
	journal-iso = {EPILEPSIA},
	journal = {EPILEPSIA},
	volume = {65},
	unique-id = {34714085},
	issn = {0013-9580},
	abstract = {This study was undertaken to develop a standardized grading system based on expert consensus for evaluating the level of confidence in the localization of the epileptogenic zone (EZ) as reported in published studies, to harmonize and facilitate systematic reviews in the field of epilepsy surgery.We conducted a Delphi study involving 22 experts from 18 countries, who were asked to rate their level of confidence in the localization of the EZ for various theoretical clinical scenarios, using different scales. Information provided in these scenarios included one or several of the following data: magnetic resonance imaging (MRI) findings, invasive electroencephalography summary, and postoperative seizure outcome.The first explorative phase showed an overall interrater agreement of .347, pointing to large heterogeneity among experts' assessments, with only 17% of the 42 proposed scenarios associated with a substantial level of agreement. A majority showed preferences for the simpler scale and single-item scenarios. The successive Delphi voting phases resulted in a majority consensus across experts, with more than two thirds of respondents agreeing on the rating of each of the tested single-item scenarios. High or very high levels of confidence were ascribed to patients with either an Engel class I or class IA postoperative seizure outcome, a well-delineated EZ according to all available invasive EEG (iEEG) data, or a well-delineated focal epileptogenic lesion on MRI. MRI signs of hippocampal sclerosis or atrophy were associated with a moderate level of confidence, whereas a low level was ascribed to other MRI findings, a poorly delineated EZ according to iEEG data, or an Engel class II-IV postoperative seizure outcome.The proposed grading system, based on an expert consensus, provides a simple framework to rate the level of confidence in the EZ reported in published studies in a structured and harmonized way, offering an opportunity to facilitate and increase the quality of systematic reviews and guidelines in the field of epilepsy surgery.},
	keywords = {Grading system; Delphi; CONFIDENCE; epilepsy surgery; epileptogenic zone},
	year = {2024},
	eissn = {1528-1167},
	pages = {1346-1359},
	orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:34505166,
	title = {Temporal association between sleep spindles and ripples in the human anterior and mediodorsal thalamus},
	url = {https://m2.mtmt.hu/api/publication/34505166},
	author = {Szalárdy, Orsolya and Simor, Péter Dániel and Ujma, Przemyslaw Péter and Jordán, Zsófia and Halász, László and Erőss, Loránd and Fabó, Dániel and Bódizs, Róbert},
	doi = {10.1111/ejn.16240},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {59},
	unique-id = {34505166},
	issn = {0953-816X},
	abstract = {Sleep spindles are major oscillatory components of Non-Rapid Eye Movement (NREM) sleep, reflecting hyperpolarization-rebound sequences of thalamocortical neurons. Reports suggest a link between sleep spindles and several forms of high-frequency oscillations which are considered as expressions of pathological off-line neural plasticity in the central nervous system. Here we investigated the relationship between thalamic sleep spindles and ripples in the anterior and mediodorsal nuclei (ANT and MD) of epilepsy patients. Whole-night LFP from the ANT and MD were co-registered with scalp EEG/polysomnography by using externalized leads in 15 epilepsy patients undergoing a Deep Brain Stimulation protocol. Slow (~12 Hz) and fast (~14 Hz) sleep spindles were present in the human ANT and MD and roughly, 20% of them were associated with ripples. Ripple-associated thalamic sleep spindles were characterized by longer duration and exceeded pure spindles in terms of spindle power as indicated by time-frequency analysis. Furthermore, ripple amplitude was modulated by the phase of sleep spindles within both thalamic nuclei. No signs of pathological processes were correlated with measures of ripple and spindle association, furthermore, the density of ripple-associated sleep spindles in the ANT showed a positive correlation with verbal comprehension. Our findings indicate the involvement of the human thalamus in coalescent spindle-ripple oscillations of NREM sleep.},
	keywords = {EPILEPSY; sleep spindle; mediodorsal thalamus; ANTERIOR THALAMUS; General intelligence; thalamic ripples},
	year = {2024},
	eissn = {1460-9568},
	pages = {641-661},
	orcid-numbers = {Szalárdy, Orsolya/0000-0001-9171-1147; Simor, Péter Dániel/0000-0003-0695-166X; Ujma, Przemyslaw Péter/0000-0002-7981-3009; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351; Bódizs, Róbert/0000-0001-5341-060X}
}

@article{MTMT:34426398,
	title = {Prediction tools and risk stratification in epilepsy surgery},
	url = {https://m2.mtmt.hu/api/publication/34426398},
	author = {Hadady, Levente and Sperling, Michael R and Alcala-Zermeno, Juan Luis and French, Jacqueline A and Dugan, Patricia and Jehi, Lara and Fabó, Dániel and Klivényi, Péter and Rubboli, Guido and Beniczky, Sándor},
	doi = {10.1111/epi.17851},
	journal-iso = {EPILEPSIA},
	journal = {EPILEPSIA},
	volume = {65},
	unique-id = {34426398},
	issn = {0013-9580},
	abstract = {To conduct external validation of previously published epilepsy surgery prediction tools using a large independent multicenter dataset and to assess whether these tools can stratify patients for being operated and for becoming free of disabling seizures (ILAE 1 and 2).We analyzed a dataset of 1,562 patients, not used for tool development. We applied two scales: Epilepsy Surgery Grading Scale (ESGS) and Seizure Freedom Score (SFS), and two versions of Epilepsy Surgery Nomograms (ESNs): the original version and the modified version which included EEG data. For the ESNs we used calibration curves and concordance indexes. We stratified the patients into three tiers, for assessing the chances of attaining freedom of disabling seizures after surgery: high (ESGS 1, SFS 3-4, ESNs>70%), moderate (ESGS 2, SFS 2, ESNs 40-70%) and low (ESGS 2, SFS 0-1, ESNs<40%). We compared the three tiers as stratified by these tools, concerning the proportion of patients who were operated, and for the proportion of patients who became free of disabling seizures.The concordance indexes for the various versions of the nomograms were between 0.56 and 0.69. Both scales (ESGS, SFS) and nomograms accurately stratified the patients for becoming free of disabling seizures, with significant differences among the three tiers (p<0.05). In addition, ESGS and the modified ESN accurately stratified the patients for having been offered surgery, with significant difference among the three tiers (p<0.05).ESGS and the modified ESN (at thresholds of 40% and 70%) stratify patients undergoing presurgical evaluation into three tiers, with high, moderate and low chance for favorable outcome, with significant differences between the groups concerning having surgery and becoming free of disabling seizures. Stratifying patients for epilepsy surgery has the potential to help select the optimal candidates in underprivileged areas and better allocation of resources in developed countries.},
	year = {2024},
	eissn = {1528-1167},
	pages = {414-421},
	orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351; Klivényi, Péter/0000-0002-5389-3266}
}

@misc{MTMT:34145291,
	title = {Callosotomy and VNS surgical aspects, palliative procedures - neurosurgical view},
	url = {https://m2.mtmt.hu/api/publication/34145291},
	author = {Rydenhag, B. and Cukiert, A. and Fabó, Dániel},
	unique-id = {34145291},
	year = {2024},
	orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351}
}

@misc{MTMT:34145289,
	title = {Broadening spectrum of surgically treatable epilepsies},
	url = {https://m2.mtmt.hu/api/publication/34145289},
	author = {Fabó, Dániel},
	unique-id = {34145289},
	year = {2024},
	orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:34429139,
	title = {Number of seizure-free days with adjunctive cenobamate: post-hoc analysis of an open-label extension study},
	url = {https://m2.mtmt.hu/api/publication/34429139},
	author = {Brandt, C. and Fabó, Dániel and Milovanovic, M. and Alvarez-Baron, E. and Thangavelu, K. and Milanov, I.},
	journal-iso = {EUR J NEUROL},
	journal = {EUROPEAN JOURNAL OF NEUROLOGY},
	volume = {30},
	unique-id = {34429139},
	issn = {1351-5101},
	year = {2023},
	eissn = {1468-1331},
	pages = {171-171},
	orcid-numbers = {Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:34428820,
	title = {Prolongation of cortical sleep spindles during hippocampal interictal epileptiform discharges in epilepsy patients},
	url = {https://m2.mtmt.hu/api/publication/34428820},
	author = {Sákovics, Anna and Csukly, Gábor and Virág, Márta and Borbély, Csaba and Kelemen, Anna and Erőss, Loránd and Fabó, Dániel},
	journal-iso = {EUR J NEUROL},
	journal = {EUROPEAN JOURNAL OF NEUROLOGY},
	volume = {30},
	unique-id = {34428820},
	issn = {1351-5101},
	year = {2023},
	eissn = {1468-1331},
	pages = {624-625},
	orcid-numbers = {Csukly, Gábor/0000-0002-5006-9407; Virág, Márta/0000-0002-5594-483X; Kelemen, Anna/0000-0003-3942-3409; Erőss, Loránd/0000-0002-5796-5546; Fabó, Dániel/0000-0001-5141-5351}
}

@misc{MTMT:34428213,
	title = {Long-term results with the novel anti-seizure medication, cenobamate, in a single center in Hungary},
	url = {https://m2.mtmt.hu/api/publication/34428213},
	author = {Jordán, Zsófia and Pető, Nóra and Sákovics, Anna and Hajnal, Boglárka Zsófia and Szabó, Johanna Petra and Ujvári, Ákos and Kelemen, Anna and Fabó, Dániel},
	unique-id = {34428213},
	year = {2023},
	orcid-numbers = {Szabó, Johanna Petra/0000-0001-7690-9171; Kelemen, Anna/0000-0003-3942-3409; Fabó, Dániel/0000-0001-5141-5351}
}

@article{MTMT:34167230,
	title = {CCDH: Complexity based Causal Discovery of Hidden common cause in time series},
	url = {https://m2.mtmt.hu/api/publication/34167230},
	author = {Stippinger, Marcell and Varga, Bálint and Benkő, Zsigmond and Fabó, Dániel and Erőss, Loránd and Somogyvári, Zoltán and Telcs, András},
	doi = {10.1016/j.chaos.2023.114054},
	journal-iso = {CHAOS SOLITON FRACT},
	journal = {CHAOS SOLITONS & FRACTALS},
	volume = {176},
	unique-id = {34167230},
	issn = {0960-0779},
	year = {2023},
	eissn = {1873-2887},
	orcid-numbers = {Stippinger, Marcell/0000-0002-9954-8089; Varga, Bálint/0000-0001-5025-8518; Fabó, Dániel/0000-0001-5141-5351; Erőss, Loránd/0000-0002-5796-5546; Telcs, András/0000-0002-3205-3081}
}