@article{MTMT:30725513,
	title = {Brainstem nucleus incertus controls contextual memory formation},
	url = {https://m2.mtmt.hu/api/publication/30725513},
	author = {Szőnyi, András and Sós, Katalin Eszter and Nyilas, Rita and Schlingloff, Dániel and Domonkos, Andor and Tresóné Takács, Virág and Pósfai, Balázs and Hegedüs, Panna and Priestley, James B. and Gundlach, Andrew L. and Gulyás, Attila and Varga, Viktor and Losonczy, Attila and Freund, Tamás and Nyíri, Gábor},
	doi = {10.1126/science.aaw0445},
	journal-iso = {SCIENCE},
	journal = {SCIENCE},
	volume = {364},
	unique-id = {30725513},
	issn = {0036-8075},
	abstract = {Hippocampal pyramidal cells encode memory engrams, which guide adaptive behavior. Selection of engram-forming cells is regulated by somatostatin-positive dendrite-targeting interneurons, which inhibit pyramidal cells that are not required for memory formation. Here, we found that gamma-aminobutyric acid ( GABA)-releasing neurons of the mouse nucleus incertus (NI) selectively inhibit somatostatin-positive interneurons in the hippocampus, both monosynaptically and indirectly through the inhibition of their subcortical excitatory inputs. We demonstrated that NI GABAergic neurons receive monosynaptic inputs from brain areas processing important environmental information, and their hippocampal projections are strongly activated by salient environmental inputs in vivo. Optogenetic manipulations of NI GABAergic neurons can shift hippocampal network state and bidirectionally modify the strength of contextual fear memory formation. Our results indicate that brainstem NI GABAergic cells are essential for controlling contextual memories.},
	year = {2019},
	eissn = {1095-9203},
	orcid-numbers = {Nyilas, Rita/0000-0002-9634-9535; Tresóné Takács, Virág/0000-0002-3276-4131; Pósfai, Balázs/0000-0003-1035-565X; Hegedüs, Panna/0000-0002-9984-5729; Gulyás, Attila/0000-0003-4961-636X}
}

@article{MTMT:109461,
	title = {Persistently active cannabinoid receptors mute a subpopulation of hippocampal interneurons},
	url = {https://m2.mtmt.hu/api/publication/109461},
	author = {Losonczy, Attila and Bíró, Ágota and Nusser, Zoltán},
	doi = {10.1073/pnas.0304752101},
	journal-iso = {P NATL ACAD SCI USA},
	journal = {PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA},
	volume = {101},
	unique-id = {109461},
	issn = {0027-8424},
	year = {2004},
	eissn = {1091-6490},
	pages = {1362-1367}
}

@article{MTMT:1006362,
	title = {Potassium channel blockers tetraethylammonium and 4-aminopyridine fail to prevent microglial activation induced by elevated potassium concentration.},
	url = {https://m2.mtmt.hu/api/publication/1006362},
	author = {Ábrahám, Hajnalka and Losonczy, Attila and Czéh, Gábor and Lázár, Gyula},
	doi = {10.1556/ABiol.54.2003.1.7},
	journal-iso = {ACTA BIOL HUNG},
	journal = {ACTA BIOLOGICA HUNGARICA (1983-2018)},
	volume = {54},
	unique-id = {1006362},
	issn = {0236-5383},
	abstract = {The effect of potassium channel blocker tetraethylammonium and 4-aminopyridine was examined on the elevated K+ concentration-induced microglial activation on rat hippocampal slice preparations. Microglial cells were detected by immunohistochemisty with a monoclonal antibody (OX 42) raised against a type 3 complement receptor. During activation the morphology of the microglial cells changes and the staining intensity increases. The degree of microglial activation was determined by measuring the integrated optical density of the cells. Tetraethylammonium and 4-aminopyridine failed to reduce the elevated K+ concentration-induced microglial activation. Both potassium channel blockers, when applied on the hippocampal slices without K+, caused significantly increased microglial activation as compared to the control slices. In order to check whether the functional alteration of the neuronal population induced by 4-aminopyridine caused the activation of the microglial cells, Schaffer collaterals were cut to block spreading of epileptiform hyperactivity of the CA3 pyramidal cells to the CA1 region. No significant differences were found in microglial activation between the CA3 and CA1 regions, indicating that the effect of 4-aminopyridine on microglial cells is independent of the epileptiform activity caused by the drug.},
	year = {2003},
	eissn = {1588-256X},
	pages = {63-78}
}

@article{MTMT:109255,
	title = {Reduction of excitatory postsynaptic responses by persistently active metabotropic glutamate receptors in the hippocampus},
	url = {https://m2.mtmt.hu/api/publication/109255},
	author = {Losonczy, Attila and Somogyi, Péter Pál and Nusser, Zoltán},
	doi = {10.1152/jn.00842.2002},
	journal-iso = {J NEUROPHYSIOL},
	journal = {JOURNAL OF NEUROPHYSIOLOGY},
	volume = {89},
	unique-id = {109255},
	issn = {0022-3077},
	year = {2003},
	eissn = {1522-1598},
	pages = {1910-1919}
}

@article{MTMT:109138,
	title = {Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones},
	url = {https://m2.mtmt.hu/api/publication/109138},
	author = {Losonczy, Attila and Zhang, L and Shigemoto, R and Somogyi, Péter Pál and Nusser, Zoltán},
	doi = {10.1113/jphysiol.2002.020024},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {542},
	unique-id = {109138},
	issn = {0022-3751},
	year = {2002},
	eissn = {1469-7793},
	pages = {193-210}
}

@article{MTMT:1006448,
	title = {Rapid activation of microglial cells by hypoxia, kainic acid, and potassium ions in slice preparations of the rat hippocampus.},
	url = {https://m2.mtmt.hu/api/publication/1006448},
	author = {Ábrahám, Hajnalka and Losonczy, Attila and Czéh, Gábor and Lázár, Gyula},
	doi = {10.1016/S0006-8993(01)02569-0},
	journal-iso = {BRAIN RES},
	journal = {BRAIN RESEARCH},
	volume = {906},
	unique-id = {1006448},
	issn = {0006-8993},
	abstract = {Microglial activation induced by hypoxia, kainic acid and elevated potassium concentration, all of which alter neuronal function, was studied in hippocampal slices. The activation of microglia was detected by immunostaining with a monoclonal antibody (OX-42) raised against a type 3 complement receptor (CD11b). During activation the phenotype of microglia changes and the intensity of staining of individual cells increases. Oxygen deprivation depressed the focal responses of CA1 neurons to stratum radiatum volleys. Microglial activation was time dependent. Ten minute hypoxia caused mild activation, and after 20 min, a strong microglial reaction could be observed. Although neuronal function returned during reoxygenation, the morphological signs of microglial activation remained. Epileptiform activity of hippocampal neurons, followed by depression, was induced by application of 0.5 mM kainic acid, in a time and dose dependent manner. Washing out kainic acid did not alter microglial reaction. Elevated concentrations of potassium ions induced microglial changes similar to those induced by hypoxia and kainic acid. It is therefore suggested that an elevated extracellular potassium ion concentration may be the common factor in microglial activation observed in these experiments since this is raised both in hypoxia and under the effect of excitotoxins.},
	year = {2001},
	eissn = {1872-6240},
	pages = {115-126}
}

@article{MTMT:1579836,
	title = {Development of mossy cells in the rat dentate hilus},
	url = {https://m2.mtmt.hu/api/publication/1579836},
	author = {Losonczy, Attila and Ábrahám, Hajnalka and Czéh, Gábor and Seress, László},
	journal-iso = {J PHYSIOL-LONDON},
	journal = {JOURNAL OF PHYSIOLOGY-LONDON},
	volume = {526},
	unique-id = {1579836},
	issn = {0022-3751},
	year = {2000},
	eissn = {1469-7793},
	pages = {63P-64P}
}

@article{MTMT:1411489,
	title = {Development of mossy cells in the rat dentate hilus},
	url = {https://m2.mtmt.hu/api/publication/1411489},
	author = {Losonczy, Attila and Ábrahám, Hajnalka and Czéh, Gábor and Seress, László},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {12},
	unique-id = {1411489},
	issn = {0953-816X},
	year = {2000},
	eissn = {1460-9568},
	pages = {160-160}
}

@article{MTMT:1008736,
	title = {Postnatal development of CA3 pyramidal and hilar mossy cells using combined intracellular recording and filling techniques.},
	url = {https://m2.mtmt.hu/api/publication/1008736},
	author = {Losonczy, Attila and Ábrahám, Hajnalka and Czéh, Gábor and Seress, László},
	journal-iso = {EUR J NEUROSCI},
	journal = {EUROPEAN JOURNAL OF NEUROSCIENCE},
	volume = {11},
	unique-id = {1008736},
	issn = {0953-816X},
	year = {2000},
	eissn = {1460-9568},
	pages = {160}
}

@misc{MTMT:1008749,
	title = {The mechanism of microglial activation studied on rat hippocampal slices exposed to elevated concentration of potassium and 4-aminopyridine.},
	url = {https://m2.mtmt.hu/api/publication/1008749},
	author = {Losonczy, Attila and Ábrahám, Hajnalka and Czéh, Gábor and Lázár, Gyula},
	unique-id = {1008749},
	year = {1999}
}