TY  - THES
AU  - Martirosyan, Mihran
TI  - Evaluation of learning curve and safety aspects of phased radiofrequency ablation procedures for pulmonary vein isolation in atrial fibrillation
PY  - 2017
UR  - https://m2.mtmt.hu/api/publication/3293973
ID  - 3293973
N1  - Tudományág: klinikai orvostudományok
Témavezető: Csanádi Zoltán
Beadás éve: 2017
A védés időpontja: 2017-09-22 13:00
A fokozat odaítélésének dátuma: 2017-11-08

Debreceni Egyetem, Laki Kálmán Doktori Iskola
Debrecen, Magyarország
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy-Baló, Edina
AU  - Martirosyan, Mihran
AU  - Sándorfi, Gábor
AU  - Hajas, Orsolya
AU  - Levente, Lánczi
AU  - Berényi, Ervin László
AU  - Lilla, Ladányi
AU  - Kiss, Alexandra
AU  - Édes, István
AU  - Csanádi, Zoltán
TI  - Cerebral micro-embolization during pulmonary vein isolation: relation to post-ablation silent cerebral ischemia
JF  - CARDIOLOGY JOURNAL
J2  - CARDIOL J
VL  - 24
PY  - 2017
IS  - 3
SP  - 234
EP  - 241
PG  - 8
SN  - 1897-5593
DO  - 10.5603/CJ.a2017.0030
UR  - https://m2.mtmt.hu/api/publication/3227096
ID  - 3227096
AB  - Background: High incidences of silent cerebral ischemia (SCI) have been revealed by diffusion-weighted magnetic resonance imaging (DW MRI) after pulmonary vein isolation (PVI) for atrial fibrillation. A high number of mostly gaseous micro-embolic signals (MESs) was detected by transcranial Doppler (TCD) during PVI. In this investigation the possible relationship between MESs detected intraoperatively by TCD and new SCI on DW MRI post-ablation is reported. Methods: 27 consecutive atrial fibrillation patients (6 female, age median: 64 interquartile range: 13.23) undergoing PVI with the pulmonary vein ablation catheter, pre- and post-ablation DW MRI and intraoperative MES detection by TCD were included in the study. Procedures were performed on a therapeutic international normalized ratio (2–3) and with a target activated clotting time ≥ 350 s in all patients. DW MRI scans performed pre- and post-ablation revealed new SCI in 6 out of 27 (22%) patients. Results: The median (interquartile range) MES count recorded during the whole procedure was 1642 (912) in patients with and 1019 (529) in those without SCI (p = 0.129). The number of MESs recorded during pulmonary vein angiography was significantly higher in patients as compared to those without a new lesion on the post-ablation DW MRI: 257 (249) vs. 110 (71), respectively (p = 0.0009). On multivariate logistic regression, the total MES count was predictive of SCI in patients older than 68 years. Conclusions: Micro-embolus generation detected by TCD during pulmonary vein angiography significantly correlates with new SCI on DW MRI post-ablation.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Kiss, Alexandra
AU  - Gábor, Sándorfi
AU  - Nagy-Baló, Edina
AU  - Martirosyan, Mihran
AU  - Csanádi, Zoltán
TI  - Phased RF Ablation: Results and Concerns
JF  - JOURNAL OF ATRIAL FIBRILLATION
J2  - JOURNAL OF ATRIAL FIBRILLATION
VL  - 8
PY  - 2015
IS  - 1
SP  - 45
EP  - 53
PG  - 9
SN  - 1941-6911
DO  - 10.4022/jafib.1240
UR  - https://m2.mtmt.hu/api/publication/2972852
ID  - 2972852
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Martirosyan, Mihran
AU  - Kiss, Alexandra
AU  - Nagy-Baló, Edina
AU  - Sándorfi, Gábor
AU  - Hajas, Orsolya
AU  - Tint, D
AU  - Édes, István
AU  - Csanádi, Zoltán
TI  - Learning curve in circular multipolar radiofrequency ablation of atrial fibrillation
JF  - CARDIOLOGY JOURNAL
J2  - CARDIOL J
VL  - 22
PY  - 2015
IS  - 3
SP  - 260
EP  - 265
PG  - 6
SN  - 1897-5593
DO  - 10.5603/CJ.a2014.0085
UR  - https://m2.mtmt.hu/api/publication/2759407
ID  - 2759407
LA  - English
DB  - MTMT
ER  -