@article{MTMT:34772009,
	title = {Thermal diffusity in copper benzene-1,3,5-tricarboxylate–reduced graphite oxide mechanical composites},
	url = {https://m2.mtmt.hu/api/publication/34772009},
	author = {Gál, Márton and Samaniego Andrade, Samantha Kathiuska and Fehér, Anna Éva and Farkas, Attila and Madarász, János and Horváth, Lili and Gordon, Péter and Kovács, Róbert Sándor and Nagyné László, Krisztina},
	doi = {10.1007/s10973-024-13021-x},
	journal-iso = {J THERM ANAL CALORIM},
	journal = {JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY},
	unique-id = {34772009},
	issn = {1388-6150},
	abstract = {Metal organic frameworks (MOFs) and particularly copper benzene-1,3,5-tricarboxylate (HKUST-1) are excellent materials for gas storage (e.g., CH 4 , N 2 , H 2 adsorption) and gas separation. In this work, reduced graphene oxide (RGO)–HKUST-1 mechanical mixtures were studied in order to reveal the effect of RGO content on the pressure tolerance of the texture and heat conductivity. HKUST-1 was obtained by two different synthesis routes. Air-dried MOF and RGO were thoroughly mixed prior to the compression. Powder XRD and Raman spectroscopy were used to characterize the response of the crystal structure, while low-temperature nitrogen adsorption was used the follow the adsorption properties of the pellets. Finally, the "flash" heat pulse method was used to assess the thermal properties. The gas adsorption isotherms revealed that the adsorption capacity decreases when RGO is added. Based on Raman and XRD results, we found that the synthesis route has an effect on multiple scales. We experimentally confirmed that evaluation of the thermal diffusivity requires a model more complex than the simple Fourier equation, due to the inherent heterogeneous structure of the material. A good approximation of the Fourier coefficient of thermal diffusivity was obtained using the parameters of the Guyer–Krumhansl equation. The heat pulse experiments also revealed possible size-dependent behavior.},
	year = {2024},
	eissn = {1572-8943},
	orcid-numbers = {Fehér, Anna Éva/0000-0002-2366-6388; Farkas, Attila/0000-0002-8877-2587; Kovács, Róbert Sándor/0000-0001-5822-6035; Nagyné László, Krisztina/0000-0003-4499-3983}
}

@article{MTMT:34771157,
	title = {Machine vision-based non-destructive dissolution prediction of meloxicam-containing tablets},
	url = {https://m2.mtmt.hu/api/publication/34771157},
	author = {Mészáros, Lilla Alexandra and Madarász, Lajos and Kádár, Szabina and Ficzere, Máté and Farkas, Attila and Nagy, Zsombor Kristóf},
	doi = {10.1016/j.ijpharm.2024.124013},
	journal-iso = {INT J PHARM},
	journal = {INTERNATIONAL JOURNAL OF PHARMACEUTICS},
	volume = {655},
	unique-id = {34771157},
	issn = {0378-5173},
	abstract = {Machine vision systems have emerged for quality assessment of solid dosage forms in the pharmaceutical industry. These can offer a versatile tool for continuous manufacturing while supporting the framework of process analytical technology, quality-by-design, and real-time release testing. The aim of this work is to develop a digital UV/VIS imaging-based system for predicting the in vitro dissolution of meloxicam-containing tablets. The alteration of the dissolution profiles of the samples required different levels of the critical process parameters, including compression force, particle size and content of the API. These process parameters were predicted non-destructively by multivariate analysis of UV/VIS images taken from the tablets. The dissolution profile prediction was also executed using solely the image data and applying artificial neural networks. The prediction error (RMSE) of the dissolution profile points was less than 5%. The alteration of the API content directly affected the maximum concentrations observed at the end of the dissolution tests. This parameter was predicted with a relative error of less than 10% by PLS models that are based on the color components of UV and VIS images. In conclusion, this paper presents a modern, non-destructive PAT solution for real-time testing of the dissolution of tablets. © 2024 The Author(s)},
	keywords = {meloxicam; Quality assessment; artificial neural network; Machine vision; Dissolution testing; Dissolution prediction},
	year = {2024},
	eissn = {1873-3476},
	orcid-numbers = {Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34759117,
	title = {UV–VIS imaging-based investigation of API concentration fluctuation caused by the sticking behaviour of pharmaceutical powder blends},
	url = {https://m2.mtmt.hu/api/publication/34759117},
	author = {Péterfi, Orsolya and Mészáros, Lilla Alexandra and Szabó-Szőcs, Bence and Ficzere, Máté and Sipos, Emese and Farkas, Attila and Galata, Dorián László and Nagy, Zsombor Kristóf},
	doi = {10.1016/j.ijpharm.2024.124010},
	journal-iso = {INT J PHARM},
	journal = {INTERNATIONAL JOURNAL OF PHARMACEUTICS},
	volume = {655},
	unique-id = {34759117},
	issn = {0378-5173},
	abstract = {Surface powder sticking in pharmaceutical mixing vessels poses a risk to the uniformity and quality of drug formulations. This study explores methods for evaluating the amount of pharmaceutical powder mixtures adhering to the metallic surfaces. Binary powder blends consisting of amlodipine and microcrystalline cellulose (MCC) were used to investigate the effect of the mixing order on the adherence to the vessel wall. Elevated API concentrations were measured on the wall and within the dislodged material from the surface, regardless of the mixing order of the components. UV imaging was used to determine the particle size and the distribution of the API on the metallic surface. The results were compared to chemical maps obtained by Raman chemical imaging. The combination of UV and VIS imaging enabled the rapid acquisition of chemical maps, covering a substantially large area representative of the analysed sample. UV imaging was also applied in tablet inspection to detect tablets that fail to meet the content uniformity criteria. The results present powder adherence as a possible source of poor content uniformity, highlighting the need for 100% inspection of pharmaceutical products to ensure product quality and safety.},
	year = {2024},
	eissn = {1873-3476},
	orcid-numbers = {Péterfi, Orsolya/0000-0002-1921-1452; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34753165,
	title = {Insight into the Structure and Redox Chemistry of [Carbonatotetraamminecobalt(III)] Permanganate and Its Monohydrate as Co-Mn-Oxide Catalyst Precursors of the Fischer-Tropsch Synthesis},
	url = {https://m2.mtmt.hu/api/publication/34753165},
	author = {Béres, Kende Attila and Dürvanger, Zsolt and Homonnay, Zoltán and Nagyné Bereczki, Laura and Barta Holló, Berta and Farkas, Attila and Petruševski, Vladimir M. and Kótai, László},
	doi = {10.3390/inorganics12040094},
	journal-iso = {INORGANICS},
	journal = {INORGANICS},
	volume = {12},
	unique-id = {34753165},
	abstract = {[Carbonatotetraamminecobalt(III)] permanganate monohydrate was synthesized first in the metathesis reaction of [Co(NH3)4CO3]NO3 and NaMnO4 in aqueous solution. Its thermal dehydration at 100 °C resulted in phase-pure [Co(NH3)4CO3]MnO4 (compound 1). Compounds 1 and 2 (i.e., the hydrated form) were studied with IR, far-IR, and low-temperature Raman spectroscopies, and their vibrational modes were assigned. The lattice parameters were determined by powder X-ray diffraction (PXRD) and single crystal X-ray diffraction (SXRD) methods for the triclinic and orthorhombic compounds 1 and 2, respectively. The detailed structure of compound 2 was determined, and the role of hydrogen bonds in the structural motifs was clarified. UV studies on compounds 1 and 2 showed the distortion of the octahedral geometry of the complex cation during dehydration because of the partial loss of the hydrogen bonds between the crystal water and the ligands of the complex cation. The thermal decomposition consists of a solid phase quasi-intramolecular redox reaction between the ammonia ligands and permanganate anions with the formation of ammonia oxidation products (H2O, NO, N2O, and CO2). The solid phase reaction product is amorphous cobalt manganese oxide containing ammonium, carbonate (and nitrate) anions. The temperature-controlled thermal decomposition of compound 2 in toluene at 110 °C showed that one of the decomposition intermediates is ammonium nitrate. The decomposition intermediates are transformed into Co1.5Mn1.5O4 spinel with MnCo2O4 structure upon further heating. Solid compound 2 gave the spinel at 500 °C both in an inert and air atmosphere, whereas the sample pre-treated in toluene at 110 °C without and with the removal of ammonium nitrate by aqueous washing, gave the spinel already at 300 and 400 °C, respectively. The molten NH4NO3 is a medium to start spinel crystallization, but its decomposition stops further crystal growth of the spinel phase. By this procedure, the particle size of the spinel product as low as ~4.0 nm could be achieved for the treatments at 300 and 400 °C, and it increased only to 5.7 nm at 500 °C. The nano-sized mixed cobalt manganese oxides are potential candidates as Fischer-Tropsch catalysts.},
	year = {2024},
	eissn = {2304-6740},
	orcid-numbers = {Béres, Kende Attila/0000-0003-4257-0581; Dürvanger, Zsolt/0000-0002-2652-4916; Homonnay, Zoltán/0000-0001-5299-5394; Barta Holló, Berta/0000-0002-5786-442X; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34544805,
	title = {Quantitative and qualitative analysis of cell culture media powders for mammalian cells by Raman microscopy},
	url = {https://m2.mtmt.hu/api/publication/34544805},
	author = {Hirsch, Edit and Bornemissza, Zsuzsanna and Nagy, Zsombor Kristóf and Marosi, György and Farkas, Attila},
	doi = {10.1016/j.saa.2024.123906},
	journal-iso = {SPECTROCHIM ACTA A},
	journal = {SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY},
	volume = {310},
	unique-id = {34544805},
	issn = {1386-1425},
	year = {2024},
	eissn = {1873-3557},
	orcid-numbers = {Marosi, György/0000-0002-4774-2023; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34342443,
	title = {Image-based simultaneous particle size distribution and concentration measurement of powder blend components with deep learning and machine vision},
	url = {https://m2.mtmt.hu/api/publication/34342443},
	author = {Ficzere, Máté and Péterfi, Orsolya and Farkas, Attila and Nagy, Zsombor Kristóf and Galata, Dorián László},
	doi = {10.1016/j.ejps.2023.106611},
	journal-iso = {EUR J PHARM SCI},
	journal = {EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES},
	volume = {191},
	unique-id = {34342443},
	issn = {0928-0987},
	year = {2023},
	eissn = {1879-0720},
	orcid-numbers = {Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34316828,
	title = {Spectroscopic and structural characterization of hexaamminecobalt(III) dibromide permanganate},
	url = {https://m2.mtmt.hu/api/publication/34316828},
	author = {Barta Holló, Berta and Bayat, Niloofar and Nagyné Bereczki, Laura and Petrusevski, Vladimir and Béres, Kende Attila and Farkas, Attila and Szilágyi, Imre Miklós and Kótai, László},
	doi = {10.2298/JSC230702062B},
	journal-iso = {J SERB CHEM SOC},
	journal = {JOURNAL OF THE SERBIAN CHEMICAL SOCIETY},
	volume = {88},
	unique-id = {34316828},
	issn = {0352-5139},
	abstract = {Structural and spectroscopic characterization (SXRD, IR, liq. N2 temperature Raman, UV) of hexaamminecobalt(III) dibromide permanganate, [Co(NH3)6]Br2(MnO4) (compound 1) are described. There is a 3D hydrogen bond network including N-H???O-Mn and N-H???Br interactions, which could serve as potential reaction centers for solid-phase redox reactions between the ammonia ligands and/or bromide ions as reductants and permanganate ions as oxidant agents. The effect of the nature of halogen ions on the structural and spectroscopic properties of [Co(NH3)6]Br2(MnO4) and the analogous chloride compound, [Co(NH3)6]Cl2(MnO4) (compound 2) are discussed in detail.},
	year = {2023},
	eissn = {1820-7421},
	pages = {1237-1252},
	orcid-numbers = {Barta Holló, Berta/0000-0002-5786-442X; Béres, Kende Attila/0000-0003-4257-0581; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34131207,
	title = {Comparing the Performance of Raman and Near-Infrared Imaging in the Prediction of the In Vitro Dissolution Profile of Extended-Release Tablets Based on Artificial Neural Networks},
	url = {https://m2.mtmt.hu/api/publication/34131207},
	author = {Galata, Dorián László and Gergely, Szilveszter and Nagy, Rebeka and Slezsák, János and Ronkay, Ferenc György and Nagy, Zsombor Kristóf and Farkas, Attila},
	doi = {10.3390/ph16091243},
	journal-iso = {PHARMACEUTICALS-BASE},
	journal = {PHARMACEUTICALS},
	volume = {16},
	unique-id = {34131207},
	abstract = {In this work, the performance of two fast chemical imaging techniques, Raman and near-infrared (NIR) imaging is compared by utilizing these methods to predict the rate of drug release from sustained-release tablets. Sustained release is provided by adding hydroxypropyl methylcellulose (HPMC), as its concentration and particle size determine the dissolution rate of the drug. The chemical images were processed using classical least squares; afterwards, a convolutional neural network was applied to extract information regarding the particle size of HPMC. The chemical images were reduced to an average HPMC concentration and a predicted particle size value; these were used as inputs in an artificial neural network with a single hidden layer to predict the dissolution profile of the tablets. Both NIR and Raman imaging yielded accurate predictions. As the instrumentation of NIR imaging allows faster measurements than Raman imaging, this technique is a better candidate for implementing a real-time technique. The introduction of chemical imaging in the routine quality control of pharmaceutical products would profoundly change quality assurance in the pharmaceutical industry.},
	year = {2023},
	eissn = {1424-8247},
	orcid-numbers = {Gergely, Szilveszter/0000-0003-1945-526X; Ronkay, Ferenc György/0000-0003-0525-1493; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34077482,
	title = {Carbonization of Zr-loaded thiourea-functionalized styrene-divinylbenzene copolymers: An easy was to synthesize Nano-ZrO2@C and Nano-(ZrC, ZrO2)@C composites},
	url = {https://m2.mtmt.hu/api/publication/34077482},
	author = {Martiz Chalen, Jose Alejandro and Károly, Zoltán and Nagyné Bereczki, Laura and Trif, László and Farkas, Attila and Kállay-Menyhárd, Alfréd and Kótai, László},
	doi = {10.3390/jcs7080306},
	journal-iso = {J COMPOSITES SCI},
	journal = {JOURNAL OF COMPOSITES SCIENCE},
	volume = {7},
	unique-id = {34077482},
	year = {2023},
	eissn = {2504-477X},
	orcid-numbers = {Trif, László/0000-0002-3960-1829; Farkas, Attila/0000-0002-8877-2587}
}

@article{MTMT:34037505,
	title = {Crystal Nanoarchitectonics and Characterization of the Octahedral Iron(III)–Nitrate Complexes with Isomer Dimethylurea Ligands},
	url = {https://m2.mtmt.hu/api/publication/34037505},
	author = {Béres, Kende Attila and Homonnay, Zoltán and Nagyné Bereczki, Laura and Dürvanger, Zsolt and Petruševski, Vladimir M. and Farkas, Attila and Kótai, László},
	doi = {10.3390/cryst13071019},
	journal-iso = {CRYSTALS},
	journal = {CRYSTALS},
	volume = {13},
	unique-id = {34037505},
	abstract = {Three octahedral iron(III) nitrate complexes with dimethylated urea ligand isomers, [hexakis(N,N’-dimethylurea-O)iron(III)] nitrate (compound 1), trans-[diaquatetrakis(N,N-dimethylurea-O)iron(III)] nitrate (compound 2), and [hexakis(N,N-dimethylurea-O)iron(III)] nitrate trihydrate (compound 3) were prepared and characterized with single crystal X-ray diffraction, IR, Raman and UV–Vis methods. In compounds 1 and 3, six dimethylurea ligands coordinate to the central FeIII ion via the oxygen in octahedral geometry and the ligands are arranged in a propeller-like manner, dividing the complex cations into two sides. In compound 1, the dimethylurea propellers screw in the opposite direction on the two sides of the complex and in compound 3, they are arranged with the same handedness on the two sides. The complexes have helical chirality. The two sides of the complex cations differ not only in the rotation direction of the ligands but also in the hydrogen bond formation. On one side of the complex cation, the ligands form intermolecular hydrogen bonds only with the crystal waters, meanwhile on the other side of the complex, the ligands form hydrogen bonds only with the nitrate ions. In compound 2, [Fe(N,N-dimethylurea)4(H2O)2]3+ cations form layers that are separated by interconnected NO3− ions forming a hydrogen bonding system and connecting the complex cations A-s and B-s. The three crystallographically different nitrate ions each form four hydrogen bonds in a way that they have one bidentate O atom and two monodentate O atoms; however, the anions differ in their hydrogen bonding. The spectroscopic characteristics of compound 2 were determined by IR measurements on the deuterated compound 2 as well.},
	year = {2023},
	eissn = {2073-4352},
	orcid-numbers = {Béres, Kende Attila/0000-0003-4257-0581; Homonnay, Zoltán/0000-0001-5299-5394; Dürvanger, Zsolt/0000-0002-2652-4916; Petruševski, Vladimir M./0000-0002-4796-4929; Farkas, Attila/0000-0002-8877-2587}
}