@mastersthesis{MTMT:30798816, title = {New approaches in the treatment of primary central nervous system tumors}, url = {https://m2.mtmt.hu/api/publication/30798816}, author = {Mózes, Petra}, doi = {10.14232/phd.9994}, publisher = {SZTE}, unique-id = {30798816}, year = {2019}, orcid-numbers = {Mózes, Petra/0000-0002-2411-7719} } @article{MTMT:3205343, title = {Volumetric response of intracranial meningioma after photon or particle irradiation}, url = {https://m2.mtmt.hu/api/publication/3205343}, author = {Mózes, Petra and Dittmar, JO and Habermehl, D and Tonndorf-Martini, E and Hideghéty, Katalin and Dittmar, A and Debus, J and Combs, SE}, doi = {10.1080/0284186X.2016.1259659}, journal-iso = {ACTA ONCOL}, journal = {ACTA ONCOLOGICA}, volume = {56}, unique-id = {3205343}, issn = {0284-186X}, keywords = {Aged; Adult; Female; Middle Aged; Male; Humans; Retrospective Studies; Case-Control Studies; Aged, 80 and over; Treatment Outcome; Young Adult; Radiotherapy Dosage; proton therapy; Photons; Radiotherapy, Intensity-Modulated; Tumor Burden/*radiation effects; Meningioma/*pathology/*radiotherapy; Meningeal Neoplasms/*pathology/*radiotherapy; Heavy Ion Radiotherapy; Brain Neoplasms/pathology/radiotherapy}, year = {2017}, eissn = {1651-226X}, pages = {431-437}, orcid-numbers = {Mózes, Petra/0000-0002-2411-7719; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:3118609, title = {The Expression of Checkpoint and DNA Repair Genes in Head and Neck Cancer as Possible Predictive Factors}, url = {https://m2.mtmt.hu/api/publication/3118609}, author = {Rusz, Orsolya and Pál, Margit and Szilágyi, Éva and Rovó, László and Varga, Zoltán and Gyaponyi-Tomisa, Bernadett and Fábián, Gabriella and Kovács, Levente and Nagy, Olga Mária and Mózes, Petra and Reisz, Zita and Tiszlavicz, László and Deák, Péter and Kahán, Zsuzsanna}, doi = {10.1007/s12253-016-0088-z}, journal-iso = {PATHOL ONCOL RES}, journal = {PATHOLOGY AND ONCOLOGY RESEARCH}, volume = {23}, unique-id = {3118609}, issn = {1219-4956}, abstract = {DNA damage response failure may influence the efficacy of DNA-damaging treatments. We determined the expression of 16 genes involved in distinct DNA damage response pathways, in association with the response to standard therapy. Twenty patients with locoregionally advanced, squamous cell head and neck carcinoma were enrolled. The treatment included induction chemotherapy (iChT) with docetaxel, cisplatin and 5-fluorouracil followed by concomitant chemoradiotherapy (ChRT) or radiotherapy (RT) alone. The volumetric metabolic therapeutic response was determined by [18F]FDG-PET/CT. In the tumor and matched normal tissues collected before treatment, the gene expressions were examined via the quantitative real-time polymerase chain reaction (qRT-PCR). The down-regulation of TP53 was apparently associated with a poor response to iChT, its up-regulation with complete regression in 2 cases. 7 cases with down-regulated REV1 expression showed complete regression after ChRT/RT, while 1 case with REV1 overexpression was resistant to RT. The overexpression of WRN was an independent predictor of tumor relapse. Our results suggest that an altered expression of REV1 predicts sensitivity to RT, while WRN overexpression is an unfavorable prognostic factor.}, year = {2017}, eissn = {1532-2807}, pages = {253-264}, orcid-numbers = {Rusz, Orsolya/0000-0001-5726-4072; Rovó, László/0000-0003-1782-1756; Varga, Zoltán/0000-0001-8537-6282; Fábián, Gabriella/0000-0002-2323-4948; Kovács, Levente/0000-0002-3226-3740; Nagy, Olga Mária/0000-0003-1471-5165; Mózes, Petra/0000-0002-2411-7719; Tiszlavicz, László/0000-0003-1134-6587; Kahán, Zsuzsanna/0000-0002-5021-8775} } @article{MTMT:2946462, title = {Evaluation of the good tumor response of embryonal tumor with abundant neuropil and true rosettes (ETANTR).}, url = {https://m2.mtmt.hu/api/publication/2946462}, author = {Mózes, Petra and Hauser, Péter and Hortobágyi, Tibor and Benyó, Gábor and Peták, István and Garami, Miklós and Cserháti, Adrienn and Bartyik, Katalin and Bognár, László and Nagy, Zoltán and Turányi, Eszter and Hideghéty, Katalin}, doi = {10.1007/s11060-015-1938-3}, journal-iso = {J NEURO-ONCOL}, journal = {JOURNAL OF NEURO-ONCOLOGY}, volume = {126}, unique-id = {2946462}, issn = {0167-594X}, abstract = {The embryonal tumor with abundant neuropil and true rosettes is a rare and highly malignant variant of embryonal brain tumors. It usually affects infants and young children under the age of 4 years and exhibits a very aggressive course with a dismal prognosis. For the 68 cases reported to date the mean age at diagnosis was 25.42 months (range 3-57 months). Survival data are available for 48 children (including our case): the median overall survival is 13.0 months, though 6 (9 %) of the children have had a relative long survival (>30 months). The aggressive combined treatment, involving primary surgical tumor removal, adjuvant polychemotherapy, including high-dose chemotherapy with stem cell transplantation, radiotherapy and radiochemotherapy, might play an important role in the longer survival. We have performed a literature review and we present here a multimodal-treated case of a 2- year-old girl with a long survival, who was reoperated when recurrence occurred. The residual tumor demonstrated a good response to temozolomide radiochemotherapy (craniospinal axis + boost) and followed by maintenance temozolomide. The described complex aggressive treatment option might be considered for future cases of this tumor entity.}, year = {2016}, eissn = {1573-7373}, pages = {99-105}, orcid-numbers = {Mózes, Petra/0000-0002-2411-7719; Hauser, Péter/0000-0002-8307-8975; Hortobágyi, Tibor/0000-0001-5732-7942; Peták, István/0000-0003-0422-9286; Garami, Miklós/0000-0003-4298-2746; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:3144900, title = {Simultaneous integrated boost, a novel approach in the management of brain metastases}, url = {https://m2.mtmt.hu/api/publication/3144900}, author = {Dobi, Ágnes and Cserháti, Adrienn and Maráz, Anikó and Mózes, Petra and Fodor, Emese and Együd, Zsófia and Szabó, Csilla and Kószó, Renáta Lilla and Varga, Zoltán and Gróh, F and Kahán, Zsuzsanna and Csenki, Melinda and Barzó, Pál and Tiszlavicz, László and Hideghéty, Katalin}, doi = {10.1016/S0167-8140(15)41291-5}, journal-iso = {RADIOTHER ONCOL}, journal = {RADIOTHERAPY AND ONCOLOGY}, volume = {115}, unique-id = {3144900}, issn = {0167-8140}, year = {2015}, eissn = {1879-0887}, pages = {S700-S701}, orcid-numbers = {Maráz, Anikó/0000-0002-2018-8413; Mózes, Petra/0000-0002-2411-7719; Fodor, Emese/0009-0008-6961-6731; Kószó, Renáta Lilla/0000-0002-1958-7839; Varga, Zoltán/0000-0001-8537-6282; Kahán, Zsuzsanna/0000-0002-5021-8775; Barzó, Pál/0000-0001-8717-748X; Tiszlavicz, László/0000-0003-1134-6587; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:3144899, title = {Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.}, url = {https://m2.mtmt.hu/api/publication/3144899}, author = {Gunther, S and Ostheimer, C and Stangl, S and Specht, HM and Mózes, Petra and Jesinghaus, M and Vordermark, D and Combs, SE and Peltz, F and Jung, MP and Multhoff, G}, doi = {10.3389/fimmu.2015.00556}, journal-iso = {FRONT IMMUNOL}, journal = {FRONTIERS IN IMMUNOLOGY}, volume = {6}, unique-id = {3144899}, issn = {1664-3224}, abstract = {Heat-shock protein 70 (Hsp70) is frequently found on the plasma membrane of a large number of malignant tumors including non-small cell lung cancer (NSCLC) and gets released into the blood circulation in lipid vesicles. On the one hand, a membrane (m)Hsp70-positive phenotype correlates with a high aggressiveness of the tumor; on the other hand, mHsp70 serves as a target for natural killer (NK) cells that had been pre-stimulated with Hsp70-peptide TKD plus low-dose interleukin-2 (TKD/IL-2). Following activation, NK cells show an up-regulated expression of activatory C-type lectin receptors, such as CD94/NKG2C, NKG2D, and natural cytotoxicity receptors (NCRs; NKp44, NKp46, and NKp30) and thereby gain the capacity to kill mHsp70-positive tumor cells. With respect to these results, the efficacy of ex vivo TKD/IL-2 stimulated, autologous NK cells is currently tested in a proof-of-concept phase II clinical trial in patients with squamous cell NSCLC after radiochemotherapy (RCT) at the TUM. Inclusion criteria are histological proven, non-resectable NSCLC in stage IIIA/IIIB, clinical responses to RCT and a mHsp70-positive tumor phenotype. The mHsp70 status is determined in the serum of patients using the lipHsp70 ELISA test, which enables the quantification of liposomal and free Hsp70. Squamous cell and adeno NSCLC patients had significantly higher serum Hsp70 levels than healthy controls. A significant correlation of serum Hsp70 levels with the gross tumor volume was shown for adeno and squamous cell NSCLC. However, significantly elevated ratios of activated CD69(+)/CD94(+) NK cells that are associated with low serum Hsp70 levels were observed only in patients with squamous cell lung cancer. These data might provide a first hint that squamous cell NSCLC is more immunogenic than adeno NSCLC.}, year = {2015}, eissn = {1664-3224}, pages = {556}, orcid-numbers = {Mózes, Petra/0000-0002-2411-7719} } @article{MTMT:2911350, title = {18FDG-PET/CT szerepe fej-nyak daganatok kezelésében és a sugárterápiás tumortérfogat meghatározásában - Az SZTE Onkoterápiás Klinikai eredményeinek értékelése}, url = {https://m2.mtmt.hu/api/publication/2911350}, author = {Hideghéty, Katalin and Cserháti, Adrienn and Besenyi, Zsuzsanna and Zag, Levente and Gaál, Szilvia and Együd, Zsófia and Mózes, Petra and Szántó, Erika and Csenki, Melinda and Rusz, Orsolya and Varga, Zoltán and Dobi, Ágnes and Maráz, Anikó and Pávics, László and Lengyel, Zsolt}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {59}, unique-id = {2911350}, issn = {0025-0244}, year = {2015}, eissn = {2060-0399}, pages = {103-110}, orcid-numbers = {Hideghéty, Katalin/0000-0001-7080-2365; Besenyi, Zsuzsanna/0000-0001-9115-9620; Mózes, Petra/0000-0002-2411-7719; Rusz, Orsolya/0000-0001-5726-4072; Varga, Zoltán/0000-0001-8537-6282; Maráz, Anikó/0000-0002-2018-8413; Pávics, László/0000-0002-7319-1667} } @misc{MTMT:3144934, title = {Comparison oft the Volumetric Response of Intracranial Meningiomas after Irradiation by Photons or Particles}, url = {https://m2.mtmt.hu/api/publication/3144934}, author = {Dittmar, JO and Mózes, Petra and Habermehl, D and Dittmar, A and Debus, J and Combs, SE}, unique-id = {3144934}, year = {2014} } @article{MTMT:3144903, title = {Reirradiation of brain tumors in young ages (7-40 years)}, url = {https://m2.mtmt.hu/api/publication/3144903}, author = {Mózes, Petra and Szanto, E and Csenki, Melinda and Valicsek, Erzsébet and Fodor, Emese and Tiszlavicz, L and Cserháti, Adrienn and Barzó, Pál and Mencser, Zoltán and Hideghéty, Katalin}, doi = {10.1016/S0167-8140(15)31199-3}, journal-iso = {RADIOTHER ONCOL}, journal = {RADIOTHERAPY AND ONCOLOGY}, volume = {111}, unique-id = {3144903}, issn = {0167-8140}, year = {2014}, eissn = {1879-0887}, pages = {S13-S14}, orcid-numbers = {Mózes, Petra/0000-0002-2411-7719; Barzó, Pál/0000-0001-8717-748X; Hideghéty, Katalin/0000-0001-7080-2365} } @article{MTMT:2805958, title = {Sürgősségi sugárkezelés az onkológiában}, url = {https://m2.mtmt.hu/api/publication/2805958}, author = {Hideghéty, Katalin and Dobi, Ágnes and Mózes, Petra and Cserháti, Adrienn}, journal-iso = {KLINIKAI ONKOLÓGIA}, journal = {KLINIKAI ONKOLÓGIA}, volume = {1}, unique-id = {2805958}, issn = {2064-5058}, year = {2014}, pages = {273-280}, orcid-numbers = {Hideghéty, Katalin/0000-0001-7080-2365; Mózes, Petra/0000-0002-2411-7719} }