@article{MTMT:31376140,
	title = {Ruptured Aortic Aneurysm and Dissection Related Death: an Autopsy Database Analysis},
	url = {https://m2.mtmt.hu/api/publication/31376140},
	author = {Pál, Dániel and Szilágyi, Brigitta and Berczeli, Márton and Szalay, Csaba Imre and Sárdy, Balázs and Oláh, Zoltán and Székely, Tamás and Rácz, Gergely and Banga, Péter and Czinege, Zsófia and Sótonyi, Péter},
	doi = {10.1007/s12253-020-00835-x},
	journal-iso = {PATHOL ONCOL RES},
	journal = {PATHOLOGY AND ONCOLOGY RESEARCH},
	volume = {26},
	unique-id = {31376140},
	issn = {1219-4956},
	year = {2020},
	eissn = {1532-2807},
	pages = {2391-2399},
	orcid-numbers = {Oláh, Zoltán/0000-0002-9598-9290; Székely, Tamás/0000-0001-9985-859X; Banga, Péter/0000-0001-8419-863X; Czinege, Zsófia/0000-0003-2609-7595; Sótonyi, Péter/0000-0002-2216-4298}
}

@article{MTMT:3376691,
	title = {LAPTM4B gene copy number gain is associated with inferior response to anthracycline-based chemotherapy in hormone receptor negative breast carcinomas},
	url = {https://m2.mtmt.hu/api/publication/3376691},
	author = {Rusz, Orsolya and Papp, O and Vízkeleti, Laura and Molnar, BA and Bende, KC and Lotz, Gábor and Ács, Balázs and Kahán, Zsuzsanna and Székely, Tamás and Bathori, A and Szundi, C and Kulka, Janina and Szállási, Zoltán and Tőkés, Anna-Mária},
	doi = {10.1007/s00280-018-3602-z},
	journal-iso = {CANCER CHEMOTH PHARM},
	journal = {CANCER CHEMOTHERAPY AND PHARMACOLOGY},
	volume = {82},
	unique-id = {3376691},
	issn = {0344-5704},
	abstract = {PURPOSE: To determine the associations between lysosomal-associated transmembrane protein 4b (LAPTM4B) gene copy number and response to different chemotherapy regimens in hormone receptor negative (HR-) primary breast carcinomas. PATIENTS AND METHODS: Two cohorts were analyzed: (1) 69 core biopsies from HR-breast carcinomas treated with neoadjuvant chemotherapy (anthracycline based in 72.5% of patients and non-anthracycline based in 27.5% of patients). (2) Tissue microarray (TMA) of 74 HR-breast carcinomas treated with adjuvant therapy (77.0% of the patients received anthracycline, 17.6% of the patients non-anthracycline-based therapy, and in 5.4% of the cases, no treatment data are available). Interphase FISH technique was applied on pretreatment core biopsies (cohort I) and on TMAs (cohort II) using custom-made dual-labelled FISH probes (LAPTM4B/CEN8q FISH probe Abnova Corp.). RESULTS: In the neoadjuvant cohort in the anthracycline-treated group, we observed a significant difference (p = 0.029) of average LAPTM4B copy number between the non-responder and pathological complete responder groups (4.1 +/- 1.1 vs. 2.6 +/- 0.1). In the adjuvant setting, the anthracycline-treated group of metastatic breast carcinomas was characterized by higher LAPTM4B copy number comparing to the non-metastatic ones (p = 0.046). In contrast, in the non-anthracycline-treated group of patients, we did not find any LAPTM4B gene copy number differences between responder vs. non-responder groups or between metastatic vs. non-metastatic groups. CONCLUSION: Our results confirm the possible role of the LAPTM4B gene in anthracycline resistance in HR- breast cancer. Analyzing LAPTM4B copy number pattern may support future treatment decision.},
	year = {2018},
	eissn = {1432-0843},
	pages = {139-147},
	orcid-numbers = {Rusz, Orsolya/0000-0001-5726-4072; Vízkeleti, Laura/0000-0001-6870-3499; Lotz, Gábor/0000-0002-6921-8978; Ács, Balázs/0000-0002-0972-4633; Kahán, Zsuzsanna/0000-0002-5021-8775; Székely, Tamás/0000-0001-9985-859X; Kulka, Janina/0000-0001-6498-5943; Szállási, Zoltán/0000-0001-5395-7509; Tőkés, Anna-Mária/0000-0002-9581-7536}
}

@article{MTMT:3068409,
	title = {Predictive value of somatic mutations for the development of malignancy in thyroid nodules benign by cytopathology},
	url = {https://m2.mtmt.hu/api/publication/3068409},
	author = {Halászlaki, Csaba and Tóbiás, Bálint and Balla, Bernadett and Kósa, János and Horányi, János and Bölöny, E and Nagy, Zsolt and Speer, Gábor and Járay, Balázs and Székely, Eszter and Istók, Roland and Székely, Tamás and Putz, Zsuzsanna and Dank, Magdolna and Lakatos, Péter and Takács, István},
	doi = {10.4158/EP151057.OR},
	journal-iso = {ENDOCR PRACT},
	journal = {ENDOCRINE PRACTICE},
	volume = {22},
	unique-id = {3068409},
	issn = {1530-891X},
	year = {2016},
	eissn = {1934-2403},
	pages = {1081-1087},
	orcid-numbers = {Tóbiás, Bálint/0000-0003-4343-1866; Balla, Bernadett/0000-0003-2465-1804; Nagy, Zsolt/0000-0002-9648-1851; Székely, Eszter/0000-0001-5039-8721; Istók, Roland/0000-0001-9172-8205; Székely, Tamás/0000-0001-9985-859X; Putz, Zsuzsanna/0000-0002-0674-337X; Dank, Magdolna/0000-0002-4442-8733; Lakatos, Péter/0000-0002-7652-3671; Takács, István/0000-0002-7810-4833}
}

@article{MTMT:3040245,
	title = {Reliability of immunocytochemistry and fluorescence in situ hybridization on fine-needle aspiration cytology samples of breast cancers: A comparative study},
	url = {https://m2.mtmt.hu/api/publication/3040245},
	author = {Ács, Balázs and Szekely, N and Szász, Attila Marcell and Lotz, Gábor and Székely, Tamás and Istók, Roland and Székely, Eszter and Madaras, Lilla and Kulka, Janina and Járay, Balázs},
	doi = {10.1002/dc.23463},
	journal-iso = {DIAGN CYTOPATHOL},
	journal = {DIAGNOSTIC CYTOPATHOLOGY},
	volume = {44},
	unique-id = {3040245},
	issn = {8755-1039},
	abstract = {INTRODUCTION: To characterize breast tumors and metastases, fine-needle aspiration cytology (FNAB) can be a favorable first choice. However, the diagnostic accuracy of ancillary tests applied to FNAB samples is yet to be validated. PATIENTS AND METHODS: We examined 110 breast cancer patients' paired cytological and surgical resection specimens evaluated between 2005 and 2014. Comparison of ER and Her2 immunocytochemical (ICC) and immunohistochemical (IHC) staining and HER2 fluorescence in situ hybridization (FISH) was performed. RESULTS: Significant difference (p < 0.001) and moderate correlation (kappa = 0.446) were noted between results of 97 paired ICC an IHC reactions for ER expression. ICC for ER status had a sensitivity of 75%, specificity of 100%, positive predictive value (PPV) of 100%, and negative predictive value (NPV) of 38.2%. Significant difference (p = 0.012) and moderate correlation (kappa = 0.541) were found between results of 77 paired ICC an IHC reactions for Her2 expression. The Her2 ICC had a sensitivity of 54%, specificity of 95.4%, PPV of 66.7%, and NPV of 92.6%. The results of FISH carried out on 23 paired samples of FNAB and surgical specimens indicated perfect correlation (kappa = 1.000) and no significant difference (p = 1.000). FISH performed on FNAB has sensitivity, specificity, PPV, and NPV of 100%. CONCLUSION: The correlation of ICC and IHC is moderate regarding ER and Her2 expression of the same tumor. FISH performed on FNAB samples is suitable to categorize primary and metastatic breast cancer in regard of HER2 gene amplification status and can be used as a predictive test in respect of therapies targeting HER2. Diagn. Cytopathol. 2016. (c) 2016 Wiley Periodicals, Inc.},
	year = {2016},
	eissn = {1097-0339},
	pages = {466-471},
	orcid-numbers = {Ács, Balázs/0000-0002-0972-4633; Szász, Attila Marcell/0000-0003-2739-4196; Lotz, Gábor/0000-0002-6921-8978; Székely, Tamás/0000-0001-9985-859X; Istók, Roland/0000-0001-9172-8205; Székely, Eszter/0000-0001-5039-8721; Madaras, Lilla/0000-0002-4137-4696; Kulka, Janina/0000-0001-6498-5943}
}

@article{MTMT:2963615,
	title = {Claudin-1 as a Biomarker of Cervical Cytology and Histology},
	url = {https://m2.mtmt.hu/api/publication/2963615},
	author = {Benczik, Márta and Galamb, Ádám and Koiss, R and Kovacs, A and Járay, Balázs and Székely, Tamás and Szekerczés, Tímea and Schaff, Zsuzsa and Sobel, Gábor and Jeney, Csaba},
	doi = {10.1007/s12253-015-9990-z},
	journal-iso = {PATHOL ONCOL RES},
	journal = {PATHOLOGY AND ONCOLOGY RESEARCH},
	volume = {22},
	unique-id = {2963615},
	issn = {1219-4956},
	abstract = {Several immunochemistry tests are used for triaging human papilloma virus (HPV) and cytology positive cases in cervical cancer screening and as an adjunct test to diagnose cervical cancer. Claudin-1 (CLDN1) protein is a major component of the tight junction, shown to have altered expression in cervical cancer. In this study, value of CLDN1 was analysed as a screening and triage immunochemistry test compared to cytology and HPV testing. A population of 352 women attending colposcopic referral visits resulting in cervical conisation and a second population of 150 women attending routine gynaecological visits with negative cervical cytology were enrolled in a multi-centre clinical study in Hungary. Cytology and HPV (Genoid Full Spectrum HPV Amplification and Detection System) testing were carried out along with immunocytochemistry for CLDN1, and as a reference, using CINtec p16 Cytology Kit. Three different evaluation protocols were used which assessed immunostaining characteristics with or without cytological readings. High correlation observable between p16INK4a and CLDN1 established CLDN1 as a competing marker in cervical cancer. Concordance of CLDN1 immunostaining of cervical intraepithelial neoplasia 2 and above (CIN2+) positives was 84.0 % (73.8-89.3); concordance of CIN2+ negatives was 69.0 % (59.6-75.8). In conclusion, CLDN1 has similar diagnostic potential as p16INK4a, our results established it as a histological and cytological biomarker with the potential to improve the clinical performance of cervical cytology and histology.},
	year = {2016},
	eissn = {1532-2807},
	pages = {179-188},
	orcid-numbers = {Benczik, Márta/0000-0001-9315-1403; Galamb, Ádám/0000-0003-2912-2928; Székely, Tamás/0000-0001-9985-859X; Szekerczés, Tímea/0000-0002-7373-8730; Schaff, Zsuzsa/0000-0002-6429-8059; Sobel, Gábor/0000-0003-3910-7668; Jeney, Csaba/0000-0001-7017-4899}
}

@article{MTMT:2927668,
	title = {Genetic Alterations in Hungarian Patients with Papillary Thyroid Cancer},
	url = {https://m2.mtmt.hu/api/publication/2927668},
	author = {Tóbiás, Bálint and Halászlaki, Csaba and Balla, Bernadett and Kósa, János and Árvai, Kristóf and Horváth, Péter and Takács, István and Nagy, Zsolt and Horváth, Evelin and Horányi, János and Járay, Balázs and Székely, Eszter and Székely, Tamás and Győri, Gabriella and Putz, Zsuzsanna and Dank, Magdolna and Valkusz, Zsuzsanna and Vasas, Béla and Iványi, Béla and Lakatos, Péter},
	doi = {10.1007/s12253-015-9969-9},
	journal-iso = {PATHOL ONCOL RES},
	journal = {PATHOLOGY AND ONCOLOGY RESEARCH},
	volume = {22},
	unique-id = {2927668},
	issn = {1219-4956},
	abstract = {The incidence of thyroid cancers is increasing worldwide. Some 
		somatic oncogene mutations (BRAF, NRAS, HRAS, KRAS) as well as gene 
		translocations (RET/PTC, PAX8/PPAR-gamma) have been associated with 
		the development of thyroid cancer. In our study, we analyzed these 
		genetic alterations in 394 thyroid tissue samples (197 papillary 
		carcinomas and 197 healthy). The somatic mutations and 
		translocations were detected by Light Cycler melting method and 
		Real-Time Polymerase Chain Reaction techniques, respectively. In 
		tumorous samples, 86 BRAF (44.2 %), 5 NRAS (3.1 %), 2 HRAS (1.0 %) 
		and 1 KRAS (0.5 %) mutations were found, as well as 9 RET/PTC1 (4.6 
		%) and 1 RET/PTC3 (0.5 %) translocations. No genetic alteration was 
		seen in the non tumorous control thyroid tissues. No correlation 
		was detected between the genetic variants and the pathological 
		subtypes of papillary cancer as well as the severity of the 
		disease. Our results are only partly concordant with the data found 
		in the literature.},
	year = {2016},
	eissn = {1532-2807},
	pages = {27-33},
	orcid-numbers = {Tóbiás, Bálint/0000-0003-4343-1866; Balla, Bernadett/0000-0003-2465-1804; Árvai, Kristóf/0000-0001-8774-937X; Takács, István/0000-0002-7810-4833; Nagy, Zsolt/0000-0002-9648-1851; Székely, Eszter/0000-0001-5039-8721; Székely, Tamás/0000-0001-9985-859X; Putz, Zsuzsanna/0000-0002-0674-337X; Dank, Magdolna/0000-0002-4442-8733; Valkusz, Zsuzsanna/0000-0003-1928-6160; Lakatos, Péter/0000-0002-7652-3671}
}

@article{MTMT:2958331,
	title = {Az aspirációs citológia szerepe a daganatdiagnosztikában.},
	url = {https://m2.mtmt.hu/api/publication/2958331},
	author = {Székely, Eszter and Istók, Roland and Székely, Tamás and Kovács, I and Somorácz, Áron and Járay, Balázs},
	journal-iso = {MAGYAR ONKOLÓGIA},
	journal = {MAGYAR ONKOLÓGIA},
	volume = {58},
	unique-id = {2958331},
	issn = {0025-0244},
	abstract = {Fine needle aspiration biopsy (FNAB) of focal lesions is a quick, relatively simple and cost-effective diagnostic method. However, performing aspirations and interpreting smears require skill and experience. Before initiating an aspiration the doctor needs to be aware of the limits of cytology as it is vital to know what kind of diagnostic issues can be answered upon a smear and what kind of questions cannot. Traditionally FNAB was performed without radiologic guidance, and therefore almost only palpable lesions were aspirated. Since ultrasound (US) has become widely used in medicine, it is axiomatical that FNAB is ideally performed with US guidance not only for the protection of the patients but also for targeting the lesion more safely. Several cytologists find US guidance unnecessary as a routinely used examination, which may lead to unsatisfactory smears and false negative results. This means not only a loss for the patient, but leads to a negative judgement of this diagnostic method. Our interventional cytology diagnostic team developed a working method resulting in excellent statistical results. In the followings we would like to share our experience refined the past two decades to restore the reputation of this diagnostic method.},
	keywords = {Aged; Middle Aged; Male; Humans; Sensitivity and Specificity; False Negative Reactions; palpation; *Ultrasonography, Interventional; *Biopsy, Fine-Needle; Thyroid Neoplasms/*diagnosis; Pancreatic Neoplasms/*diagnosis/pathology; Liver Neoplasms/*diagnosis/secondary; Histocytological Preparation Techniques/*methods},
	year = {2014},
	eissn = {2060-0399},
	pages = {311-323},
	orcid-numbers = {Székely, Eszter/0000-0001-5039-8721; Istók, Roland/0000-0001-9172-8205; Székely, Tamás/0000-0001-9985-859X; Somorácz, Áron/0000-0003-4015-2263}
}

@article{MTMT:2336120,
	title = {Detecting somatic oncogene mutations in FNA samples of cold nodules in Hungary},
	url = {https://m2.mtmt.hu/api/publication/2336120},
	author = {Tóbiás, Bálint and Balla, Bernadett and Kósa, János and Horányi, János and Takács, István and Nagy, Zsolt and Horváth, Péter and Járay, Balázs and Székely, Eszter and Istók, Roland and Székely, Tamás and Lakatos, Péter},
	doi = {10.1530/endoabs.32.P1108},
	journal-iso = {ENDOCR ABSTR},
	journal = {ENDOCRINE ABSTRACTS},
	volume = {32},
	unique-id = {2336120},
	issn = {1470-3947},
	year = {2013},
	eissn = {1479-6848},
	orcid-numbers = {Tóbiás, Bálint/0000-0003-4343-1866; Balla, Bernadett/0000-0003-2465-1804; Takács, István/0000-0002-7810-4833; Nagy, Zsolt/0000-0002-9648-1851; Székely, Eszter/0000-0001-5039-8721; Istók, Roland/0000-0001-9172-8205; Székely, Tamás/0000-0001-9985-859X; Lakatos, Péter/0000-0002-7652-3671}
}

@article{MTMT:1632012,
	title = {Expression of claudins and their prognostic significance in non-invasive urothelial neoplasms of the human urinary bladder},
	url = {https://m2.mtmt.hu/api/publication/1632012},
	author = {Székely, Eszter and Törzsök, Péter and Riesz, Péter and Korompay, Anna and Fintha, Attila and Székely, Tamás and Lotz, Gábor and Nyirády, Péter and Romics, Imre and Tímár, József and Schaff, Zsuzsa and Kiss, András},
	doi = {10.1369/0022155411418829},
	journal-iso = {J HISTOCHEM CYTOCHEM},
	journal = {JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY},
	volume = {59},
	unique-id = {1632012},
	issn = {0022-1554},
	year = {2011},
	eissn = {1551-5044},
	pages = {932-941},
	orcid-numbers = {Székely, Eszter/0000-0001-5039-8721; Törzsök, Péter/0000-0003-0661-388X; Riesz, Péter/0000-0001-5304-5841; Korompay, Anna/0000-0003-0736-6876; Fintha, Attila/0000-0002-0519-8170; Székely, Tamás/0000-0001-9985-859X; Lotz, Gábor/0000-0002-6921-8978; Nyirády, Péter/0000-0002-7037-4919; Romics, Imre/0000-0001-8094-5108; Tímár, József/0000-0001-9183-0859; Schaff, Zsuzsa/0000-0002-6429-8059; Kiss, András/0000-0002-7453-3163}
}

@article{MTMT:1781927,
	title = {E-cadherin-expresszió vizsgálata hólyagrákban},
	url = {https://m2.mtmt.hu/api/publication/1781927},
	author = {Riesz, Péter and Székely, Eszter and Török, V and Székely, Tamás and Romics, Imre},
	journal-iso = {MAGYAR UROLÓGIA},
	journal = {MAGYAR UROLÓGIA},
	volume = {19},
	unique-id = {1781927},
	issn = {0864-8921},
	year = {2007},
	pages = {159-163},
	orcid-numbers = {Riesz, Péter/0000-0001-5304-5841; Székely, Eszter/0000-0001-5039-8721; Székely, Tamás/0000-0001-9985-859X; Romics, Imre/0000-0001-8094-5108}
}