@article{MTMT:34096011, title = {Viscoelasticity of Liposomal Dispersions}, url = {https://m2.mtmt.hu/api/publication/34096011}, author = {Budai, Lívia and Budai, Marianna and Pápay, Zsófia Edit and Szalkai, Petra and Niczinger, Noémi and Kijima, S. and Sugibayashi, K. and Antal, István and Kállai-Szabó, Nikolett}, doi = {10.3390/nano13162340}, journal-iso = {NANOMATERIALS-BASEL}, journal = {NANOMATERIALS}, volume = {13}, unique-id = {34096011}, year = {2023}, eissn = {2079-4991}, orcid-numbers = {Budai, Lívia/0000-0002-6720-5989; Budai, Marianna/0000-0003-4947-9924; Pápay, Zsófia Edit/0000-0002-7653-1065; Niczinger, Noémi/0000-0002-2076-0643; Antal, István/0000-0002-5434-201X; Kállai-Szabó, Nikolett/0000-0002-8164-3993} } @article{MTMT:34041182, title = {Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology}, url = {https://m2.mtmt.hu/api/publication/34041182}, author = {Budai, Lívia and Budai, Marianna and Bozó, Tamás and Agócs, Gergely and Kellermayer, Miklós and Antal, István}, doi = {10.3390/molecules28135125}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {28}, unique-id = {34041182}, issn = {1420-3049}, abstract = {Knowledge of the physical and chemical properties of phospholipids, such as phase transition temperatures (Tc), is of great importance in order to reveal the functionalities of biological and artificial membranes. Our research group developed an oscillatory rheological method for the simple and rapid determination of phase transition temperatures (Tc). The phospholipids constructing the membranes undergo conformational changes at their Tc, which cause alterations of viscoelastic properties of the molecules. The oscillatory technique recommended by us proved to be appropriate to reveal the altered molecular properties of phospholipids as tracking the slightest changes in the viscoelasticity. Our study demonstrates the abrupt changes in rheological properties at Tc for the following phospholipids: 1,2-Dimyristoyl-sn-glycero-3-Phosphocholine (DMPC), 1,2-Dipalmitoyl-sn-glycero-3-Phosphatidylcholine (DPPC), and 1,2-Distearoyl-sn-glycero-3-Phosphocholine (DSPC), proving that the applied methodology is adequate for determining the Tc of phospholipids.}, year = {2023}, eissn = {1420-3049}, orcid-numbers = {Budai, Lívia/0000-0002-6720-5989; Budai, Marianna/0000-0003-4947-9924; Bozó, Tamás/0000-0002-2643-0661; Agócs, Gergely/0000-0003-2489-3790; Kellermayer, Miklós/0000-0002-5553-6553; Antal, István/0000-0002-5434-201X} } @article{MTMT:34009564, title = {Rheological Considerations of Pharmaceutical Formulations: Focus on Viscoelasticity}, url = {https://m2.mtmt.hu/api/publication/34009564}, author = {Budai, Lívia and Budai, Marianna and Pápay, Zsófia Edit and Vilimi, Zsófia and Antal, István}, doi = {10.3390/gels9060469}, journal-iso = {GELS-BASEL}, journal = {GELS (BASEL)}, volume = {9}, unique-id = {34009564}, abstract = {Controlling rheological properties offers the opportunity to gain insight into the physical characteristics, structure, stability and drug release rate of formulations. To better understand the physical properties of hydrogels, not only rotational but also oscillatory experiments should be performed. Viscoelastic properties, including elastic and viscous properties, are measured using oscillatory rheology. The gel strength and elasticity of hydrogels are of great importance for pharmaceutical development as the application of viscoelastic preparations has considerably expanded in recent decades. Viscosupplementation, ophthalmic surgery and tissue engineering are just a few examples from the wide range of possible applications of viscoelastic hydrogels. Hyaluronic acid, alginate, gellan gum, pectin and chitosan are remarkable representatives of gelling agents that attract great attention applied in biomedical fields. This review provides a brief summary of rheological properties, highlighting the viscoelasticity of hydrogels with great potential in biomedicine.}, year = {2023}, eissn = {2310-2861}, orcid-numbers = {Budai, Lívia/0000-0002-6720-5989; Budai, Marianna/0000-0003-4947-9924; Pápay, Zsófia Edit/0000-0002-7653-1065; Vilimi, Zsófia/0000-0002-9241-5267; Antal, István/0000-0002-5434-201X} } @article{MTMT:34010818, title = {Lipid Nano-Vehicles for Cyanide Antagonism: A Mini-Review}, url = {https://m2.mtmt.hu/api/publication/34010818}, author = {Jayanna, PK and Budai, Lívia and Petrikovics, I.}, journal-iso = {J Drug Design Discov Res}, journal = {Journal of Drug Design and Discovery Research}, volume = {2}, unique-id = {34010818}, issn = {2349-9036}, year = {2021}, pages = {79-80}, orcid-numbers = {Budai, Lívia/0000-0002-6720-5989} } @article{MTMT:32496688, title = {Rheological Studies of Hydrogels and Liposomal Dispersions: Factors Influencing the Viscoelastic Properties}, url = {https://m2.mtmt.hu/api/publication/32496688}, author = {Szalkai, Petra and Pápay, Zsófia Edit and Budai, Lívia and Sárády-Kesztyűs, Ágnes and Antal, István}, journal-iso = {ACTA PHARM HUNG}, journal = {ACTA PHARMACEUTICA HUNGARICA}, volume = {91}, unique-id = {32496688}, issn = {0001-6659}, year = {2021}, eissn = {1587-1495}, pages = {320-321}, orcid-numbers = {Pápay, Zsófia Edit/0000-0002-7653-1065; Budai, Lívia/0000-0002-6720-5989; Antal, István/0000-0002-5434-201X} } @article{MTMT:32107318, title = {Inclusion complexation of the anticancer drug pomalidomide with cyclodextrins: fast dissolution and improved solubility}, url = {https://m2.mtmt.hu/api/publication/32107318}, author = {Szabó, Zoltán-István and Orbán, György and Borbás, Enikő and Csicsák, Dóra and Kádár, Szabina and Fiser, Béla and Dobó, Máté and Horváth, Péter and Kiss, Eszter and Budai, Lívia and Dobos, Judit and Pálla, Tamás and Őrfi, László and Völgyi, Gergely and Tóth, Gergő}, doi = {10.1016/j.heliyon.2021.e07581}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {7}, unique-id = {32107318}, year = {2021}, eissn = {2405-8440}, orcid-numbers = {Csicsák, Dóra/0000-0003-3663-3566; Fiser, Béla/0000-0003-0603-4626; Horváth, Péter/0000-0001-7149-4173; Kiss, Eszter/0000-0001-7953-9348; Budai, Lívia/0000-0002-6720-5989; Pálla, Tamás/0000-0002-1195-0621; Őrfi, László/0000-0001-6149-2385; Völgyi, Gergely/0000-0001-8990-3916; Tóth, Gergő/0000-0001-5341-319X} } @{MTMT:31608791, title = {A pici első hónapjai}, url = {https://m2.mtmt.hu/api/publication/31608791}, author = {Budai, Marianna and Budai, Lívia}, booktitle = {2 x 9 hónap biztonságban. Mit szedhetek, és mit nem? Szakemberek válaszai a babavárástól a babázásig.}, unique-id = {31608791}, year = {2020}, pages = {155-175}, orcid-numbers = {Budai, Marianna/0000-0003-4947-9924; Budai, Lívia/0000-0002-6720-5989} } @{MTMT:31608788, title = {A második 9 hónap}, url = {https://m2.mtmt.hu/api/publication/31608788}, author = {Budai, Marianna and Budai, Lívia}, booktitle = {2 x 9 hónap biztonságban. Mit szedhetek, és mit nem? Szakemberek válaszai a babavárástól a babázásig.}, unique-id = {31608788}, year = {2020}, pages = {107-139}, orcid-numbers = {Budai, Marianna/0000-0003-4947-9924; Budai, Lívia/0000-0002-6720-5989} } @{MTMT:31608783, title = {Az első 9 hónap}, url = {https://m2.mtmt.hu/api/publication/31608783}, author = {Budai, Marianna and Budai, Lívia}, booktitle = {2 x 9 hónap biztonságban. Mit szedhetek, és mit nem? Szakemberek válaszai a babavárástól a babázásig.}, unique-id = {31608783}, year = {2020}, pages = {11-77}, orcid-numbers = {Budai, Marianna/0000-0003-4947-9924; Budai, Lívia/0000-0002-6720-5989} } @article{MTMT:31409208, title = {Configuration-Controlled Crystal and/or Gel Formation of Protectedd-Glucosamines Supported by Promiscuous Interaction Surfaces and a Conformationally Heterogeneous Solution State}, url = {https://m2.mtmt.hu/api/publication/31409208}, author = {Kapros, Anita and Balázs, Attila and Harmat, Veronika and Halo, Adrienn and Budai, Lívia and Pintér, István and Karancsiné Menyhárd, Dóra and Perczel, András}, doi = {10.1002/chem.202000882}, journal-iso = {CHEM-EUR J}, journal = {CHEMISTRY-A EUROPEAN JOURNAL}, volume = {26}, unique-id = {31409208}, issn = {0947-6539}, abstract = {The configuration-dependent self-association mode of the two anomers ofO-Ac,N-Fmoc-d-glucosamine, a foldamer building block, leading to gel and/or single crystal formation is described. The beta-anomer of the sugar amino acid (2) forms a gel from various solvents (confirmed by SEM, rheology measurements, NMR, and ECD spectroscopy), whereas the alpha-anomer (1) does not form a gel with any solvent tested. Transition from the solution state to a gel is coupled to a concurrent shift of the Fmoc-groups: from a freely rotating (almost symmetrical) to a specific, asymmetric orientation. Whereas the crystal structure of the alpha-anomer is built as an evenly packed 3D system, the beta-anomer forms a looser superstructure of well-packed 2D layers. Modeling indicates that in the lowest energy, but scarcely sampled conformer of the beta-anomer, the Fmoc-group bends above the sugar moiety, stabilized by intramolecular CH <->pi interactions between the aromatic rings. It is concluded that possessing an extended and promiscuous interaction surface and a conformationally heterogeneous solution state are among the basic requirements of gel formation for a candidate molecule.}, keywords = {RESOLUTION; RECOGNITION; WATER; GLUCOSE; Crystallography; NMR spectroscopy; DRUG-DELIVERY; Hydrogels; Gelation; CH-pi interactions; gel state; CH/PI INTERACTIONS; PI-INTERACTIONS}, year = {2020}, eissn = {1521-3765}, pages = {11643-11655}, orcid-numbers = {Harmat, Veronika/0000-0002-1866-9904; Budai, Lívia/0000-0002-6720-5989; Karancsiné Menyhárd, Dóra/0000-0002-0095-5531; Perczel, András/0000-0003-1252-6416} }