TY - JOUR AU - Németh, Krisztián AU - Sterczer, Ágnes AU - Kiss, Dávid Sándor AU - Lányi, Réka Katalin AU - Hemző, Vivien AU - Vámos, Kriszta AU - Bartha, Tibor AU - Buzás, Anna AU - Lányi, Katalin TI - Determination of Bile Acids in Canine Biological Samples: Diagnostic Significance JF - METABOLITES J2 - METABOLITES VL - 14 PY - 2024 IS - 4 SP - 178 PG - 35 SN - 2218-1989 DO - 10.3390/metabo14040178 UR - https://m2.mtmt.hu/api/publication/34757219 ID - 34757219 AB - The comprehensive examination of bile acids is of paramount importance across various fields of health sciences, influencing physiology, microbiology, internal medicine, and pharmacology. While enzymatic reaction-based photometric methods remain fundamental for total BA measurements, there is a burgeoning demand for more sophisticated techniques such as liquid chromatography–tandem mass spectrometry (LC-MS/MS) for comprehensive BA profiling. This evolution reflects a need for nuanced diagnostic assessments in clinical practice. In canines, a BA assessment involves considering factors, such as food composition, transit times, and breed-specific variations. Multiple matrices, including blood, feces, urine, liver tissue, and gallbladder bile, offer insights into BA profiles, yet interpretations remain complex, particularly in fecal analysis due to sampling challenges and breed-specific differences. Despite ongoing efforts, a consensus regarding optimal matrices and diagnostic thresholds remains elusive, highlighting the need for further research. Emphasizing the scarcity of systematic animal studies and underscoring the importance of ap-propriate sampling methodologies, our review advocates for targeted investigations into BA alterations in canine pathology, promising insights into pathomechanisms, early disease detection, and therapeutic avenues. LA - English DB - MTMT ER - TY - BOOK ED - Sótonyi, Péter ED - Bartha, Tibor ED - Rácz, Bence ED - Kováts, Adrien TI - Tudományos Diákköri Konferencia előadásainak összefoglalói : 2021 PB - Állatorvostudományi Egyetem CY - Budapest PY - 2021 SP - 152 SN - 9789637149368 UR - https://m2.mtmt.hu/api/publication/32852436 ID - 32852436 LA - English DB - MTMT ER - TY - JOUR AU - Bárány, Zoltán Balázs AU - Tóth, István AU - Jócsák, Gergely AU - Frenyó V., László AU - Bartha, Tibor AU - Sterczer, Ágnes AU - Kiss, Dávid Sándor TI - Differential production of interleukin‐6 and tumor necrosis factor‐α in primary rat astrocyte cultures using two distinct methods of microglia elimination JF - CLINICAL AND EXPERIMENTAL NEUROIMMUNOLOGY J2 - CLIN EXP NEUROIMMUNOLOGY VL - 12 PY - 2021 IS - 3 SP - 192 EP - 201 PG - 10 SN - 1759-1961 DO - 10.1111/cen3.12650 UR - https://m2.mtmt.hu/api/publication/32475357 ID - 32475357 LA - English DB - MTMT ER - TY - JOUR AU - Kiss, Dávid Sándor AU - Tóth, István AU - Jócsák, Gergely AU - Bárány, Zoltán Balázs AU - Bartha, Tibor AU - Frenyó V., László AU - Horvath, Tamas L. AU - Zsarnovszky, Attila TI - Functional Aspects of Hypothalamic Asymmetry JF - BRAIN SCIENCES J2 - BRAIN SCI VL - 10 PY - 2020 IS - 6 PG - 14 SN - 2076-3425 DO - 10.3390/brainsci10060389 UR - https://m2.mtmt.hu/api/publication/31399182 ID - 31399182 AB - Anatomically, the brain is a symmetric structure. However, growing evidence suggests that certain higher brain functions are regulated by only one of the otherwise duplicated (and symmetric) brain halves. Hemispheric specialization correlates with phylogeny supporting intellectual evolution by providing an ergonomic way of brain processing. The more complex the task, the higher are the benefits of the functional lateralization (all higher functions show some degree of lateralized task sharing). Functional asymmetry has been broadly studied in several brain areas with mirrored halves, such as the telencephalon, hippocampus, etc. Despite its paired structure, the hypothalamus has been generally considered as a functionally unpaired unit, nonetheless the regulation of a vast number of strongly interrelated homeostatic processes are attributed to this relatively small brain region. In this review, we collected all available knowledge supporting the hypothesis that a functional lateralization of the hypothalamus exists. We collected and discussed findings from previous studies that have demonstrated lateralized hypothalamic control of the reproductive functions and energy expenditure. Also, sporadic data claims the existence of a partial functional asymmetry in the regulation of the circadian rhythm, body temperature and circulatory functions. This hitherto neglected data highlights the likely high-level ergonomics provided by such functional asymmetry. LA - English DB - MTMT ER - TY - JOUR AU - Kiss, Dávid Sándor AU - Tóth, István AU - Jócsák, Gergely AU - Bartha, Tibor AU - Frenyó V., László AU - Bárány, Zoltán Balázs AU - Horváth, Tamás AU - Zsarnovszky, Attila TI - Metabolic Lateralization in the Hypothalamus of Male Rats Related to Reproductive and Satiety States JF - REPRODUCTIVE SCIENCES J2 - REPROD SCI VL - 27 PY - 2020 IS - 5 SP - 1197 EP - 1205 PG - 9 SN - 1933-7191 DO - 10.1007/s43032-019-00131-3 UR - https://m2.mtmt.hu/api/publication/31260011 ID - 31260011 LA - English DB - MTMT ER - TY - BOOK ED - Sótonyi, Péter ED - Bartha, Tibor ED - Rácz, Bence ED - Kováts, Adrien TI - Tudományos Diákköri Konferencia előadásainak összefoglalói : 2019 PB - Állatorvostudományi Egyetem CY - Budapest PY - 2019 SP - 166 SN - 9789637149313 UR - https://m2.mtmt.hu/api/publication/32852508 ID - 32852508 LA - English DB - MTMT ER - TY - JOUR AU - Jócsák, Gergely AU - Ioja, Enikő AU - Kiss, Dávid Sándor AU - Tóth, István AU - Bárány, Zoltán Balázs AU - Bartha, Tibor AU - Frenyó V., László AU - Zsarnovszky, Attila TI - Endocrine Disruptors Induced Distinct Expression of Thyroid and Estrogen Receptors in Rat versus Mouse Primary Cerebellar Cell Cultures JF - BRAIN SCIENCES J2 - BRAIN SCI VL - 9 PY - 2019 IS - 12 PG - 19 SN - 2076-3425 DO - 10.3390/brainsci9120359 UR - https://m2.mtmt.hu/api/publication/31194217 ID - 31194217 LA - English DB - MTMT ER - TY - GEN AU - Jócsák, Gergely AU - Kiss, Dávid Sándor AU - Tóth, István AU - Bárány, Zoltán Balázs AU - Frenyó V., László AU - Bartha, Tibor AU - Zsarnovszky, Attila TI - Az endokrin diszruptorkezelés indukálta ösztrogén- és pajzsmirigyhormon receptor expressziós változások összehasonlítása patkány és egér modellben ET - 0 PY - 2019 UR - https://m2.mtmt.hu/api/publication/30412858 ID - 30412858 N1 - Akadémiai beszámoló LA - Hungarian DB - MTMT ER - TY - GEN AU - Bárány, Zoltán Balázs AU - Kiss, Dávid Sándor AU - Tóth, István AU - Jócsák, Gergely AU - Frenyó V., László AU - Bartha, Tibor AU - Zsarnovszky, Attila AU - Sterczer, Ágnes TI - Az oxidatív stressz és a tumor nekrózis faktor alfa (TNF-α)-termelés vizsgálata hepaticus encephalopathiaban ET - 0 PY - 2019 UR - https://m2.mtmt.hu/api/publication/30412856 ID - 30412856 N1 - Akadémiai beszámoló LA - Hungarian DB - MTMT ER - TY - JOUR AU - Bárány, Zoltán Balázs AU - Kiss, Dávid Sándor AU - Tóth, István AU - Jócsák, Gergely AU - Bartha, Tibor AU - Frenyó V., László AU - Zsarnovszky, Attila AU - Sterczer, Ágnes TI - Examination of the oxidative stress and the tumor necrosis factor (tnf)-α-production in hepatic encephalopathy JF - GLIA J2 - GLIA VL - 67 PY - 2019 IS - S1 SP - E549 EP - E550 PG - 2 SN - 0894-1491 UR - https://m2.mtmt.hu/api/publication/30412849 ID - 30412849 LA - English DB - MTMT ER -