@article{MTMT:34795832, title = {Comparative Effectiveness of Supervised and Home-Based Rehabilitation after Anterior Cruciate Ligament Reconstruction in Competitive Athletes}, url = {https://m2.mtmt.hu/api/publication/34795832}, author = {Syed, Rehan Iftikhar Bukhari and Hangody, László Rudolf and Frischmann, Gergely and Kós, Petra and Kopper, Bence and Berkes, István}, doi = {10.3390/jcm13082245}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {13}, unique-id = {34795832}, abstract = {Background: After the increasingly common anterior cruciate ligament reconstruction (ACLR) procedure in competitive athletes, rehabilitation is crucial for facilitating a timely return to sports (RTS) and preventing re-injury. This pilot study investigates the patient-reported outcomes of postoperative rehabilitation in competitive athletes, comparing supervised rehabilitation (SVR) and home-based rehabilitation (HBR). Methods: After ACLR, 60 (out of 74 screened) athletes were recruited and equally divided into HBR and SVR groups using non-probability convenience sampling, with each group comprising 15 males and 15 females. The rehabilitation outcomes in the respective groups were evaluated at 8 months using measures (Tegner Activity Scale [TAS], International Knee Documentation Committee subjective knee form [IKDC-SKF], ACL Return to Sport after Injury [ACL-RSI]) and objective parameters (isometric muscle strength, hamstring/quadricep asymmetry). RTS was evaluated at 9 months, with ACL re-injury rates recorded approximately 6 months post-RTS. Results: Both groups exhibited decreased TAS scores (HBR: 8 to 6, SVR: 8 to 7), with the SVR group demonstrating superior postoperative IKDC-SKF scores (81.82 vs. 68.43) and lower ACL-RSI scores (49.46 vs. 55.25). Isometric and isokinetic muscle strength, along with asymmetry values, was higher in the SVR group 8 months post-ACLR (p < 0.05). The SVR group showed a higher RTS rate to the same level (76.6% vs. 53.3%), while the re-injury rate was the same in both the rehabilitation groups (3.3%). Conclusions: Although both rehabilitation approaches yielded comparable outcomes, SVR may demonstrate some superior biomechanical improvements in athletes, resulting in a higher RTS rate. However, the psychological outcomes and re-injury rates did not significantly differ between the groups, emphasizing the need to address individual psychological needs during rehabilitation. Further investigation is recommended with a larger sample size to address the differences of gender among competitive athletes.}, year = {2024}, eissn = {2077-0383}, pages = {2245} } @article{MTMT:34768188, title = {Referátum - Apor Péter rovata}, url = {https://m2.mtmt.hu/api/publication/34768188}, author = {Apor, Péter}, journal-iso = {M SPORTTUD SZLE}, journal = {MAGYAR SPORTTUDOMÁNYI SZEMLE}, volume = {25}, unique-id = {34768188}, issn = {1586-5428}, year = {2024}, pages = {72-76} } @article{MTMT:34741151, title = {Progressive Irreversible Proprioceptive Piezo2 Channelopathy-Induced Lost Forced Peripheral Oscillatory Synchronization to the Hippocampal Oscillator May Explain the Onset of Amyotrophic Lateral Sclerosis Pathomechanism}, url = {https://m2.mtmt.hu/api/publication/34741151}, author = {Sonkodi, Balázs}, doi = {10.3390/cells13060492}, journal-iso = {CELLS-BASEL}, journal = {CELLS}, volume = {13}, unique-id = {34741151}, abstract = {Amyotrophic lateral sclerosis (ALS) is a mysterious lethal multisystem neurodegenerative disease that gradually leads to the progressive loss of motor neurons. A recent non-contact dying-back injury mechanism theory for ALS proposed that the primary damage is an acquired irreversible intrafusal proprioceptive terminal Piezo2 channelopathy with underlying genetic and environmental risk factors. Underpinning this is the theory that excessively prolonged proprioceptive mechanotransduction under allostasis may induce dysfunctionality in mitochondria, leading to Piezo2 channelopathy. This microinjury is suggested to provide one gateway from physiology to pathophysiology. The chronic, but not irreversible, form of this Piezo2 channelopathy is implicated in many diseases with unknown etiology. Dry eye disease is one of them where replenishing synthetic proteoglycans promote nerve regeneration. Syndecans, especially syndecan-3, are proposed as the first critical link in this hierarchical ordered depletory pathomechanism as proton-collecting/distributing antennas; hence, they may play a role in ALS pathomechanism onset. Even more importantly, the shedding or charge-altering variants of Syndecan-3 may contribute to the Piezo2 channelopathy-induced disruption of the Piezo2-initiated proton-based ultrafast long-range signaling through VGLUT1 and VGLUT2. Thus, these alterations may not only cause disruption to ultrafast signaling to the hippocampus in conscious proprioception, but could disrupt the ultrafast proprioceptive signaling feedback to the motoneurons. Correspondingly, an inert Piezo2-initiated proton-based ultrafast signaled proprioceptive skeletal system is coming to light that is suggested to be progressively lost in ALS. In addition, the lost functional link of the MyoD family of inhibitor proteins, as auxiliary subunits of Piezo2, may not only contribute to the theorized acquired Piezo2 channelopathy, but may explain how these microinjured ion channels evolve to be principal transcription activators.}, year = {2024}, eissn = {2073-4409} } @article{MTMT:34730191, title = {Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production}, url = {https://m2.mtmt.hu/api/publication/34730191}, author = {Otahal, Alexander and Kramer, Karina and Neubauer, Markus and Gulová, Slavomira and Lacza, Zsombor and Nehrer, Stefan and De Luna, Andrea}, doi = {10.1186/s13287-024-03681-9}, journal-iso = {STEM CELL RES THER}, journal = {STEM CELL RESEARCH & THERAPY}, volume = {15}, unique-id = {34730191}, issn = {1757-6512}, year = {2024}, eissn = {1757-6512}, orcid-numbers = {Otahal, Alexander/0000-0003-3705-0039} } @article{MTMT:34649518, title = {Okostelefon-szenzorokon alapuló technológia alkalmazása az otthoni gyógytorna eredményességének ellenőrzésére}, url = {https://m2.mtmt.hu/api/publication/34649518}, author = {Zsarnóczky-Dulházi, Fanni and Lelbach, Ádám Antal and Rácz, Levente and Trzaskoma, Lukasz and Berkes, István and Sümegi, Tekla and Kopper, Bence}, doi = {10.1556/650.2024.32974}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {165}, unique-id = {34649518}, issn = {0030-6002}, abstract = {Bevezetés: A világjárvány ráébresztette a társadalmat arra, hogy adódhatnak olyan különleges helyzetek, amikor a betegek nem tudnak személyesen találkozni egészségügyi szakembereikkel, az ellátás folyamatossága mégsem szakadhat meg. A gyógytornaellátás során eddig is általánosan alkalmazott eljárás volt a személyes alkalmak közötti otthoni gyakorlásra ösztönzés a terápia sikeressége érdekében. Ám a foglalkozásokon megtanult és begyakorolt feladatok ismétlésszáma és pontossága kérdéses az otthoni környezetben, ami csökkentheti az eredményességet, és növelheti a sérülésveszélyt. Célkitűzés: Kutatásunkban olyan megoldást teszteltünk, amely megfizethető és széles körben elérhető eszközöket, okostelefont és laptopot használ képernyőmegosztási technológia alkalmazásával. Módszer: A 3 hétig tartó vizsgálatunkban négy csoport (vizsgálati: fiatal, n = 50, életkor 25,6 ± 3,1 év; idősebb felnőttek, n = 50, életkor 74,8 ± 9,1 év; kontroll: fiatal, n = 20, életkor 26,25 ± 3,6 év; idősebb felnőttek, n = 20, életkor 70,15 ± 5,2 év) vett részt. A résztvevők feladata guggolási és térdemelési gyakorlatok végrehajtása volt egy előre meghatározott végtagszöghelyzetig. A vizsgálati csoport tagjai a végtagmozgások és szöghelyzetek nyomon követésére egy – goniométeres alkalmazással a combjukra rögzített – okostelefont és egy aktivált képernyőmegosztási funkcióval rendelkező laptopot használtak, amely valós idejű önellenőrzést tett lehetővé. Eredmények: A célszögtől való eltérés szignifikánsan csökkent (a guggolás esetében a fiataloknál 7,7°-ról 1,7°-ra, az idősebbeknél 16,4°-ról 7,3°-ra; térdemelés esetén a fiataloknál 10,8°-ról 3,2°-ra, az idősebbeknél 14,8°-ról 6,4°-ra), vagyis a gyakorlatok végrehajtása szignifikánsan pontosabb lett a vizsgálati csoportokban. Következtetés: Eredményeink azt mutatják, hogy amikor a résztvevők numerikus visszajelzést kaptak a laptop képernyőjén keresztül, akkor a gyakorlat végrehajtásának pontossága jelentősen megnőtt. Összehasonlításaink és statisztikai elemzéseink alapján összességében kijelenthetjük, hogy olyan, könnyen hozzáférhető eszközök és módszerek is felhasználhatók az otthoni mozgásszervi rehabilitáció eredményességének javításához, mint az okostelefon és a laptop. Orv Hetil. 2024; 165(7): 265–273.}, year = {2024}, eissn = {1788-6120}, pages = {265-273}, orcid-numbers = {Zsarnóczky-Dulházi, Fanni/0000-0002-2124-136X} } @{MTMT:34689304, title = {Kardiovaszkuláris rehabilitáció hazánkban és a világban. A szív- és bel-beteg-rehabilitáció javasolt intenzitása}, url = {https://m2.mtmt.hu/api/publication/34689304}, author = {Apor, Péter}, booktitle = {Sport és szív}, unique-id = {34689304}, year = {2023}, pages = {127-130} } @{MTMT:34689281, title = {A szív edzettségi jelei és az ezeket befolyásoló tényezők}, url = {https://m2.mtmt.hu/api/publication/34689281}, author = {Pavlik, Gábor}, booktitle = {Sport és szív}, unique-id = {34689281}, year = {2023}, pages = {69-78} } @article{MTMT:34526408, title = {Does Proprioception Involve Synchronization with Theta Rhythms by a Novel Piezo2 Initiated Ultrafast VGLUT2 Signaling?}, url = {https://m2.mtmt.hu/api/publication/34526408}, author = {Sonkodi, Balázs}, doi = {10.3390/biophysica3040046}, journal-iso = {Biophysica}, journal = {Biophysica}, volume = {3}, unique-id = {34526408}, abstract = {This opinion manuscript outlines how the hippocampal theta rhythm could receive two novel peripheral inputs. One of the ways this could be achieved is through Piezo2 channels and atypical hippocampal-like metabotropic glutamate receptors coupled to phospholipase D containing proprioceptive primary afferent terminals. Accordingly, activated proprioceptive terminal Piezo2 on Type Ia fibers synchronizes to the theta rhythm with the help of hippocampal Piezo2 and medial septal glutamatergic neurons. Second, after baroreceptor Piezo2 is entrained to activated proprioceptive Piezo2, it could turn on the Cav1.3 channels, which pace the heart rhythm and regulate pacemaker cells during cardiac sympathetic activation. This would allow the Cav1.3 channels to synchronize to theta rhythm pacemaker hippocampal parvalbumin-expressing GABAergic neurons. This novel Piezo2-initiated proton–proton frequency coupling through VGLUT2 may provide the ultrafast long-range signaling pathway for the proposed Piezo2 synchronization of the low-frequency glutamatergic cell surface membrane oscillations in order to provide peripheral spatial and speed inputs to the space and speed coding of the hippocampal theta rhythm, supporting locomotion, learning and memory. Moreover, it provides an ultrafast signaling for postural and orthostatic control. Finally, suggestions are made as to how Piezo2 channelopathy could impair this ultrafast communication in many conditions and diseases with not entirely known etiology, leading to impaired proprioception and/or autonomic disbalance.}, year = {2023}, eissn = {2673-4125}, pages = {695-710} } @misc{MTMT:34509817, title = {EFFICACY OF CORONAVIRUS DISEASE SAFETY PROTOCOL AT THE 2021 WRESTLING EUROPEAN OLYMPIC GAMES QUALIFIER IN BUDAPEST}, url = {https://m2.mtmt.hu/api/publication/34509817}, author = {Ambrus, Mira and Lacza, Zsombor and Molnár, Szabolcs Lajos and Babak, Shadgan and Éva, Kőrösi and Károly, Mensch}, unique-id = {34509817}, year = {2023} } @article{MTMT:34499299, title = {Referátum - Apor Péter rovata}, url = {https://m2.mtmt.hu/api/publication/34499299}, author = {Apor, Péter}, journal-iso = {M SPORTTUD SZLE}, journal = {MAGYAR SPORTTUDOMÁNYI SZEMLE}, volume = {24}, unique-id = {34499299}, issn = {1586-5428}, year = {2023}, pages = {60-67} }