@misc{MTMT:34091453,
	title = {CLOCK gene plays role in the genetic background of depression after stressful life events – a GWAS study},
	url = {https://m2.mtmt.hu/api/publication/34091453},
	author = {Erdelyi-Hamza, Berta and Török, Dóra and Gál, Zsófia and Gyorik, Dorka and Eszlári, Nóra and Bagdy, György and Juhász, Gabriella and Gonda, Xénia},
	unique-id = {34091453},
	year = {2023},
	orcid-numbers = {Török, Dóra/0000-0001-9213-4345; Gál, Zsófia/0000-0002-9441-1497; Eszlári, Nóra/0000-0003-4913-028X; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267; Gonda, Xénia/0000-0001-9015-4203}
}

@book{MTMT:33577345,
	title = {COVID-19 Pandemic: Mental health, life habit changes and social phenomena},
	url = {https://m2.mtmt.hu/api/publication/33577345},
	isbn = {9782832511756},
	doi = {10.3389/978-2-83251-175-6},
	editor = {Smirnova, Daria and Fountoulakis, Konstantinos N and Gonda, Xénia and Morgado, Pedro},
	publisher = {Frontiers Media S.A.},
	unique-id = {33577345},
	year = {2023},
	orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203}
}

@article{MTMT:33543493,
	title = {Prolactin-releasing peptide contributes to stress-related mood disorders and inhibits sleep/mood regulatory melanin-concentrating hormone neurons in rats.},
	url = {https://m2.mtmt.hu/api/publication/33543493},
	author = {Vas, Szilvia and Papp, Rege Sugárka and Könczöl, Katalin and Bogáthy, Emese and Papp, Noémi and Ádori, Csaba and Durst, Máté and Sípos, Klaudia and Ocskay, Klementina and Farkas, Imre and Bálint, Flóra and Ferenczi, Szilamér and Török, Bibiána and Kovács, Anita and Szabó, Evelin and Zelena, Dóra and Kovács, Krisztina and Földes, Anna and Kató, Erzsébet and Köles, László and Bagdy, György and Palkovits, Miklós and Tóth, Zsuzsanna},
	doi = {10.1523/JNEUROSCI.2139-21.2022},
	journal-iso = {J NEUROSCI},
	journal = {JOURNAL OF NEUROSCIENCE},
	volume = {43},
	unique-id = {33543493},
	issn = {0270-6474},
	abstract = {Stress disorders impair sleep, quality of life, however, their pathomechanisms are unknown. Prolactin-releasing peptide (PrRP) is a stress mediator, therefore, we hypothesised that PrRP may be involved in the development of stress disorders. PrRP is produced by the medullary A1/A2 noradrenaline (NA) cells, which transmit stress signals to forebrain centers, and by non-NA cells in the hypothalamic dorsomedial nucleus. We found in male rats that both PrRP and PrRP-NA cells innervate melanin-concentrating hormone (MCH) producing neurons in the dorsolateral hypothalamus (DLH). These cells serve as a key hub for regulating sleep and affective states. Ex vivo, PrRP hyperpolarized MCH neurons and further increased the hyperpolarization caused by NA. Following sleep deprivation, intracerebroventricular PrRP injection reduced the number of REM sleep-active MCH cells. PrRP expression in the dorsomedial nucleus was up-regulated by sleep deprivation, while down-regulated by REM sleep rebound. Both in learned helplessness paradigm and after peripheral inflammation, impaired coping with sustained stress was associated with (i) overactivation of PrRP cells, (ii) PrRP protein and receptor depletion in the DLH, and (iii) dysregulation of MCH expression. Exposure to stress in PrRP insensitive period led to increased passive coping with stress. Normal PrRP signaling, therefore, seems to protect animals against stress-related disorders. PrRP signaling in the DLH is important component of the PrRP's action, which may be mediated by MCH neurons. Moreover, PrRP receptors were downregulated in the DLH of human suicidal victims. As stress-related mental disorders are the leading cause of suicide, our findings may have particular translational relevance.SIGNIFICANCE STATEMENT:Treatment resistance to monoaminergic antidepressants is a major problem. Neuropeptides that modulate the central monoaminergic signaling are promising targets for developing alternative therapeutic strategies. We found that stress-responsive prolactin-releasing peptide (PrRP) cells innervated melanin-concentrating hormone (MCH) neurons that are crucial in the regulation of sleep and mood. PrRP inhibited MCH cell activity and enhanced the inhibitory effect evoked by noradrenaline, a classic monoamine, on MCH neurons. We observed that impaired PrRP signaling led to failure in coping with chronic/repeated stress and was associated with altered MCH expression. We found alterations of the PrRP system also in suicidal human subjects. PrRP dysfunction may underlie stress disorders, and fine-tuning MCH activity by PrRP may be an important part of the mechanism.},
	year = {2023},
	eissn = {1529-2401},
	pages = {846-862},
	orcid-numbers = {Vas, Szilvia/0000-0001-7236-5672; Papp, Rege Sugárka/0000-0002-4720-0291; Bogáthy, Emese/0000-0003-3676-1170; Papp, Noémi/0000-0001-9460-9391; Durst, Máté/0000-0002-6456-4740; Sípos, Klaudia/0000-0003-0534-7348; Ocskay, Klementina/0000-0001-5848-2506; Farkas, Imre/0000-0002-0159-4408; Földes, Anna/0000-0002-4182-7886; Kató, Erzsébet/0000-0001-5786-0405; Köles, László/0000-0001-6708-0269; Bagdy, György/0000-0001-8141-3410; Palkovits, Miklós/0000-0003-0578-0387; Tóth, Zsuzsanna/0000-0002-0628-1320}
}

@article{MTMT:33296256,
	title = {Affective temperaments mediate aggressive dimensions in bipolar disorders. A cluster analysis from a large, cross-sectional, international study},
	url = {https://m2.mtmt.hu/api/publication/33296256},
	author = {Fico, Giovanna and Janiri, Delfina and Pinna, Marco and Sagué-Vilavella, Maria and Palomo, Anna Gimenez and Oliva, Vincenzo and De Prisco, Michele and Cortez, Pablo Guzmán and Anmella, Gerard and Gonda, Xénia and Sani, Gabriele and Tondo, Leonardo and Vieta, Eduard and Murru, Andrea},
	doi = {10.1016/j.jad.2022.11.084},
	journal-iso = {J AFFECT DISORDERS},
	journal = {JOURNAL OF AFFECTIVE DISORDERS},
	volume = {323},
	unique-id = {33296256},
	issn = {0165-0327},
	abstract = {Affective temperaments show potential for aggressive behavior (AB) preventive strategies in bipolar disorder (BD). We aim to define intra-diagnostic subgroups of patients with BD based on homogeneous behaviors related to AB. Subsequently, to assess whether affective temperament dimensions may contribute to the presence and severity of AB.Patients with BD were recruited. AB was evaluated through the modified overt aggression scale (MOAS); affective temperaments were assessed with the TEMPS-A. A cluster analysis was conducted based on TEMPS-A and MOAS scores. Stepwise backward logistic regression models were used to identify the predictive factors of cluster membership.799 patients with BD were enrolled. Three clusters were determined: non-aggressive (55.5 %), self-aggressive (18 %), and hetero-aggressive (26.5 %). Depressive, irritable, and anxious temperament scores significantly increased from the non-aggressive (lower) to the self-aggressive (intermediate) and the hetero-aggressive group (highest). A positive history of a suicide attempt (B = 5.131; OR = 169.2, 95 % CI 75.9; 377) and rapid cycling (B = -0.97; OR = 0.40, 95 % CI 0.17; 0.95) predicted self-aggressive cluster membership. Atypical antipsychotics (B = 1.19; OR = 3.28, 95 % CI 2.13; 5.06) or SNRI treatment (B = 1.09; OR = 3, 95 % CI 1.57; 5.71), psychotic symptoms (B = 0.73; OR = 2.09, 95 % CI 1.34; 3.26), and history of a suicide attempt (B = -1.56; OR = 0.20, 95 % CI 0.11; 0.38) predicted hetero-aggressive cluster membership.Recall bias might have affected the recollection of AB.Clinical factors orientate the prevention of different ABs in BD. Affective temperaments might play a role in preventing AB since patients with more pronounced affective temperaments might have an increased risk of showing AB, in particular hetero-AB.},
	keywords = {mood disorders; bipolar disorder; aggressive behavior; Affective temperaments; violent behavior; Hetero-aggressive behavior},
	year = {2023},
	eissn = {1573-2517},
	pages = {327-335},
	orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203}
}

@article{MTMT:32259137,
	title = {Novel antidepressant drugs: Beyond monoamine targets},
	url = {https://m2.mtmt.hu/api/publication/32259137},
	author = {Gonda, Xénia and Döme, Péter and Neill, Joanna C. and Tarazi, Frank I.},
	doi = {10.1017/S1092852921000791},
	journal-iso = {CNS SPECTRUMS},
	journal = {CNS SPECTRUMS},
	volume = {28},
	unique-id = {32259137},
	issn = {1092-8529},
	year = {2023},
	eissn = {2165-6509},
	pages = {6-15},
	orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203; Döme, Péter/0000-0003-3847-0553; Tarazi, Frank I./0000-0001-6839-9378}
}

@article{MTMT:33648554,
	title = {INVESTIGATING THE POLYGENIC SIGNAL OF MIGRAINE: COMPARISON OF DIFFERENT COHORTS},
	url = {https://m2.mtmt.hu/api/publication/33648554},
	author = {Török, Dóra and Gál, Zsófia and Gecse, Kinga and Eszlári, Nóra and Juhász, Gabriella and Petschner, Péter},
	doi = {10.1016/j.euroneuro.2022.07.446},
	journal-iso = {EUR NEUROPSYCHOPHARM},
	journal = {EUROPEAN NEUROPSYCHOPHARMACOLOGY},
	volume = {63},
	unique-id = {33648554},
	issn = {0924-977X},
	year = {2022},
	eissn = {1873-7862},
	pages = {e249-e250},
	orcid-numbers = {Török, Dóra/0000-0001-9213-4345; Gál, Zsófia/0000-0002-9441-1497; Gecse, Kinga/0000-0002-3512-2572; Eszlári, Nóra/0000-0003-4913-028X; Juhász, Gabriella/0000-0002-5975-4267; Petschner, Péter/0000-0002-3198-858X}
}

@misc{MTMT:33643403,
	title = {Alterations of tryptophan pathway and cytokine profile in migraine patients},
	url = {https://m2.mtmt.hu/api/publication/33643403},
	author = {Gecse, Kinga and Tamás, Nagy and Bagdy, György and Juhász, Gabriella},
	unique-id = {33643403},
	year = {2022},
	orcid-numbers = {Gecse, Kinga/0000-0002-3512-2572; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267}
}

@article{MTMT:33643393,
	title = {Decreased plasma RANTES/CCL5 concentration in headache-free episodic migraine patients},
	url = {https://m2.mtmt.hu/api/publication/33643393},
	author = {Gecse, Kinga and Nagy, T. and Környei, Z. and Dénes, Á. and Bagdy, György and Juhász, Gabriella},
	journal-iso = {J HEADACHE PAIN},
	journal = {JOURNAL OF HEADACHE AND PAIN},
	volume = {23},
	unique-id = {33643393},
	issn = {1129-2369},
	keywords = {Clinical Neurology},
	year = {2022},
	eissn = {1129-2377},
	orcid-numbers = {Gecse, Kinga/0000-0002-3512-2572; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267}
}

@article{MTMT:33641776,
	title = {Why is my headache different? Functional connectivity alterations of periaqueductal gray matter in migraine and tension-type headache patients},
	url = {https://m2.mtmt.hu/api/publication/33641776},
	author = {Gecse, Kinga and K., Norbert and Dobos, Dóra and Baksa, Dániel and C., Aranyi and M., Emri and Kökönyei, Gyöngyi and Bagdy, György and Juhász, Gabriella},
	doi = {10.1016/j.nsa.2022.100552},
	journal-iso = {NEUROSCI APPL},
	journal = {NEUROSCIENCE APPLIED},
	volume = {1},
	unique-id = {33641776},
	issn = {2772-4085},
	year = {2022},
	orcid-numbers = {Gecse, Kinga/0000-0002-3512-2572; Dobos, Dóra/0000-0002-2291-8854; Baksa, Dániel/0000-0002-7826-9179; Kökönyei, Gyöngyi/0000-0001-6750-2644; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267}
}

@article{MTMT:33641764,
	title = {Tension-type headache frequency correlates with periaqueductal gray matter functional connectivity},
	url = {https://m2.mtmt.hu/api/publication/33641764},
	author = {Gecse, Kinga and Dobos, Dóra and N., Károlyi and Baksa, Dániel and C.S., Aranyi and M., Emri and Kökönyei, Gyöngyi and Bagdy, György and Juhász, Gabriella},
	doi = {10.1016/j.nsa.2022.100082},
	journal-iso = {NEUROSCI APPL},
	journal = {NEUROSCIENCE APPLIED},
	volume = {1},
	unique-id = {33641764},
	issn = {2772-4085},
	year = {2022},
	orcid-numbers = {Gecse, Kinga/0000-0002-3512-2572; Dobos, Dóra/0000-0002-2291-8854; Baksa, Dániel/0000-0002-7826-9179; Kökönyei, Gyöngyi/0000-0001-6750-2644; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267}
}