@CONFERENCE{MTMT:34016892,
	title = {Új prosztatarák diagnosztikai módszer fejlesztése},
	url = {https://m2.mtmt.hu/api/publication/34016892},
	author = {Reider, Balázs},
	booktitle = {Pannon Innovációs Nap},
	unique-id = {34016892},
	year = {2023}
}

@article{MTMT:33707474,
	title = {Capillary Gel Electrophoresis of Proteins: Historical overview and recent advances},
	url = {https://m2.mtmt.hu/api/publication/33707474},
	author = {Hajba, László and Jeong, Sunkyung and Chung, Doo Soo and Guttman, András},
	doi = {10.1016/j.trac.2023.117024},
	journal-iso = {TRAC-TREND ANAL CHEM},
	journal = {TRAC-TRENDS IN ANALYTICAL CHEMISTRY},
	volume = {162},
	unique-id = {33707474},
	issn = {0165-9936},
	abstract = {This review summarizes the fundamental principles, basic methodologies, strength and weaknesses of capillary gel electrophoresis of proteins by providing both a short historical overview and highlighting new developments and applications in biopharmaceutical, biomedical as well as food and agriculture fields. The subsets of the method including native capillary gel electrophoresis, SDS capillary gel electrophoresis, capillary gel isoelectric focusing, capillary gel isotachophoresis and capillary affinity gel electrophoresis of proteins are all critically reviewed. Relevant protein labeling techniques are also addressed.},
	year = {2023},
	eissn = {1879-3142},
	orcid-numbers = {Hajba, László/0000-0001-7937-4854; Guttman, András/0000-0002-7838-082X}
}

@article{MTMT:33573245,
	title = {Nano-Spray-Dried Levocetirizine Dihydrochloride with Mucoadhesive Carriers and Cyclodextrins for Nasal Administration},
	url = {https://m2.mtmt.hu/api/publication/33573245},
	author = {Mirankó, Mirella and Tóth, Judit and Bartos, Csilla and Ambrus, Rita and Feczkó, Tivadar},
	doi = {10.3390/pharmaceutics15020317},
	journal-iso = {PHARMACEUTICS},
	journal = {PHARMACEUTICS},
	volume = {15},
	unique-id = {33573245},
	issn = {1999-4923},
	abstract = {Antihistamines such as levocetirizine dihydrochloride (LC) are commercially used in oral tablets and oral drops to reduce allergic symptoms. In this study, LC was nano-spray-dried using three mucoadhesive polymers and four cyclodextrin species to form composite powders for nasal administration. The product was composed of hydroxypropyl methylcellulose polymer, including LC as a zwitterion, after neutralization by NaOH, and XRD investigations verified its amorphous state. This and a sulfobutylated-beta-cyclodextrin sodium salt-containing sample showed crystal peaks due to NaCl content as products of the neutralization reaction in the solutions before drying. The average particle size of the spherical microparticles was between 2.42 and 3.44 µm, except for those containing a polyvinyl alcohol excipient, which were characterized by a medium diameter of 29.80 µm. The drug was completely and immediately liberated from all the samples at pH 5.6 and 32 °C; i.e., the carriers did not change the good dissolution behavior of LC. A permeability test was carried out by dipping the synthetic cellulose ester membrane in isopropyl myristate using modified horizontal diffusion cells. The spray-dried powder with β-cyclodextrin showed the highest permeability (188.37 µg/cm2/h), as this additive was the least hydrophilic. Products prepared with other cyclodextrins (randomly methylated-beta-cyclodextrin, sulfobutylated-beta-cyclodextrin sodium salt and (hydroxypropyl)-beta-cyclodextrin) showed similar or slightly higher penetration abilities than LC. Other polymer excipients resulted in lower penetration of the active agent than the pure LC.},
	year = {2023},
	eissn = {1999-4923},
	orcid-numbers = {Ambrus, Rita/0000-0001-5496-1710}
}

@article{MTMT:32840673,
	title = {The Role of IgG Fc Region N-Glycosylation in the Pathomechanism of Rheumatoid Arthritis},
	url = {https://m2.mtmt.hu/api/publication/32840673},
	author = {Gyebrovszki, Balázs and Ács, András and Szabó, Dániel and Auer, Felícia and Novozánszki, Soma and Rojkovich, Bernadette and Magyar, Anna (Biczókné) and Hudecz, Ferenc and Vékey, Károly and Drahos, László and Sármay, Gabriella},
	doi = {10.3390/ijms23105828},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {23},
	unique-id = {32840673},
	issn = {1661-6596},
	abstract = {Anti-citrullinated protein antibodies (ACPAs) are involved in the pathogenesis of rheumatoid arthritis. N-glycosylation pattern of ACPA-IgG and healthy IgG Fc differs. The aim of this study is to determine the relative sialylation and galactosylation level of ACPAs and control IgG to assess their capability of inducing TNF alpha production, and furthermore, to analyze the correlations between the composition of Fc glycans and inflammatory markers in RA. We isolated IgG from sera of healthy volunteers and RA patients, and purified ACPAs on a citrulline-peptide column. Immunocomplexes (IC) were formed by adding an F(ab)(2) fragment of anti-human IgG. U937 cells were used to monitor the binding of IC to Fc gamma R and to trigger TNF alpha release determined by ELISA. To analyze glycan profiles, control IgG and ACPA-IgG were digested with trypsin and the glycosylation patterns of glycopeptides were analyzed by determining site-specific N-glycosylation using nano-UHPLC-MS/MS. We found that both sialylation and galactosylation levels of ACPA-IgG negatively correlate with inflammation-related parameters such as CRP, ESR, and RF. Functional assays show that dimerized ACPA-IgG significantly enhances TNF alpha release in an Fc gamma RI-dependent manner, whereas healthy IgG does not. TNF alpha production inversely correlates with the relative intensities of the GO glycoform, which lacks galactose and terminal sialic acid moieties.},
	year = {2022},
	eissn = {1422-0067},
	orcid-numbers = {Szabó, Dániel/0000-0003-3375-395X; Auer, Felícia/0000-0001-8347-7637; Hudecz, Ferenc/0000-0001-5128-9498; Drahos, László/0000-0001-9589-6652; Sármay, Gabriella/0000-0002-3066-7768}
}

@{MTMT:32637715,
	title = {Integrated method for urinary prostate specific antigen N-glycosylation profiling by capillary electrophoresis},
	url = {https://m2.mtmt.hu/api/publication/32637715},
	author = {Járvás, Gábor and Reider, Balázs and Jankovics, Hajnalka and Vonderviszt, Ferenc and Guttman, András},
	unique-id = {32637715},
	year = {2022},
	orcid-numbers = {Járvás, Gábor/0000-0002-9289-6304; Jankovics, Hajnalka/0000-0002-9746-9424; Vonderviszt, Ferenc/0000-0002-6498-8172; Guttman, András/0000-0002-7838-082X}
}

@book{MTMT:32915469,
	title = {A Triple-Internal Standard Based Glycan Structural Assignment Method For Capillary Electrophoresis Analysis Of Carbohydrates},
	url = {https://m2.mtmt.hu/api/publication/32915469},
	author = {Járvás, Gábor and Szigeti, Márton and Guttman, András and Chapman, Jeff},
	unique-id = {32915469},
	abstract = {A separation device receives a known or unknown glycan that is co-injected with three different oligomers maltooligosaccharide (MOL). A detector measures the separated glycan and the separated three different oligomers as intensity peaks that are a function of migration time. The migration times of a plurality of other oligomers of MOL are calculated from the migration times of the three different oligomers. Glucose unit (GU) values for the intensity peaks of the separated glycan are calculated by comparing their migration times to the calculated migration times of the plurality of other oligomers of MOL. The processor identifies the structure of the glycan by comparing the calculated GU values of the intensity peaks of the separated glycan to a database of GU values for known glycan structures.},
	year = {2021},
	orcid-numbers = {Járvás, Gábor/0000-0002-9289-6304; Szigeti, Márton/0000-0001-5136-8479; Guttman, András/0000-0002-7838-082X}
}

@article{MTMT:32487497,
	title = {Integrated workflow for urinary prostate specific antigen N-glycosylation analysis using sdAb partitioning and downstream capillary electrophoresis separation},
	url = {https://m2.mtmt.hu/api/publication/32487497},
	author = {Reider, Balázs and Gacsi, Eszter and Jankovics, Hajnalka and Vonderviszt, Ferenc and Szarvas, Tibor and Guttman, András and Járvás, Gábor},
	doi = {10.1016/j.aca.2021.338892},
	journal-iso = {ANAL CHIM ACTA},
	journal = {ANALYTICA CHIMICA ACTA},
	volume = {1184},
	unique-id = {32487497},
	issn = {0003-2670},
	abstract = {Prostate cancer represents the second highest malignancy rate in men in all cancer diagnoses worldwide. The development and progression of prostate cancer is not completely understood yet at molecular level, but it has been reported that changes in the N-glycosylation of prostate-specific antigen (PSA) occur during tumor genesis. In this paper we report on the development and implementation of a highthroughput capillary electrophoresis based glycan analysis workflow for urinary PSA analysis. The technology utilizes selective, high yield single domain antibody based PSA capture, followed by preconcentration and capillary electrophoresis coupled with laser-induced fluorescence detection, resulting in high resolution N-glycan profiles. Urinary PSA glycan profiles were compared to a commercially available PSA standard revealing differences in their a2,3-and a2,6-sialylated isomers, proving the excellent selectivity of the suggested workflow. This is important as sialylation classification plays an important role in the differentiation between indolent, significant and aggressive forms of prostate cancer. (c) 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).},
	keywords = {SERUM; Prostate cancer; Serum biomarkers; N-Linked glycans; urinary biomarkers},
	year = {2021},
	eissn = {1873-4324},
	orcid-numbers = {Jankovics, Hajnalka/0000-0002-9746-9424; Vonderviszt, Ferenc/0000-0002-6498-8172; Szarvas, Tibor/0000-0002-6321-0799; Guttman, András/0000-0002-7838-082X; Járvás, Gábor/0000-0002-9289-6304}
}

@article{MTMT:31929285,
	title = {Thermoresponsive Poly(N,N-diethylacrylamide-co-glycidyl methacrylate) Copolymers and Its Catalytically Active α-Chymotrypsin Bioconjugate with Enhanced Enzyme Stability},
	url = {https://m2.mtmt.hu/api/publication/31929285},
	author = {Kasza, György and Stumphauser, Tímea and Bisztrán, Márk and Szarka, Györgyi Éva and Hegedüs, Imre and Nagy, Endre and Iván, Béla},
	doi = {10.3390/polym13060987},
	journal-iso = {POLYMERS-BASEL},
	journal = {POLYMERS},
	volume = {13},
	unique-id = {31929285},
	year = {2021},
	eissn = {2073-4360},
	orcid-numbers = {Kasza, György/0000-0003-3335-8730; Hegedüs, Imre/0000-0002-1438-3511; Nagy, Endre/0000-0002-3863-4194; Iván, Béla/0000-0003-2475-6841}
}

@article{MTMT:31921234,
	title = {Flagellin-based electrochemical sensing layer for arsenic detection in water},
	url = {https://m2.mtmt.hu/api/publication/31921234},
	author = {Jankovics, Hajnalka and Szekér, P. and Tóth, Éva and Kakasi, Balázs and Lábadi, Zoltán and Saftics, András and Kalas, Benjamin and Fried, Miklós and Petrik, Péter and Vonderviszt, Ferenc},
	doi = {10.1038/s41598-021-83053-y},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {11},
	unique-id = {31921234},
	issn = {2045-2322},
	year = {2021},
	eissn = {2045-2322},
	orcid-numbers = {Jankovics, Hajnalka/0000-0002-9746-9424; Tóth, Éva/0000-0001-9788-6757; Kakasi, Balázs/0000-0001-6066-0527; Fried, Miklós/0000-0002-9194-735X; Petrik, Péter/0000-0002-5374-6952; Vonderviszt, Ferenc/0000-0002-6498-8172}
}

@article{MTMT:31886736,
	title = {The Need for Accurate Osmotic Pressure and Mass Transfer Resistances in Modeling Osmotically Driven Membrane Processes},
	url = {https://m2.mtmt.hu/api/publication/31886736},
	author = {Nagy, Endre and Hegedüs, Imre and Rehman, Danyal and Wei, Quantum J. and Ahdab, Yvana D. and Lienhard, John H.},
	doi = {10.3390/membranes11020128},
	journal-iso = {MEMBRANES-BASEL},
	journal = {MEMBRANES (BASEL)},
	volume = {11},
	unique-id = {31886736},
	year = {2021},
	eissn = {2077-0375},
	orcid-numbers = {Nagy, Endre/0000-0002-3863-4194; Hegedüs, Imre/0000-0002-1438-3511; Rehman, Danyal/0000-0001-9457-191X; Lienhard, John H./0000-0002-2901-0638}
}