TY - JOUR AU - Nemes, Attila AU - Gyenes, Nándor AU - Kormányos, Árpád AU - Vágvölgyi, Anna AU - Ambrus, Nóra AU - Balogh, László AU - Pucsok, József Márton AU - Lengyel, Csaba Attila TI - Left ventricular deformation in athletes playing sports with high dynamics—insights from the three-dimensional speckle-tracking echocardiographic MAGYAR-Sport Study JF - QUANTITATIVE IMAGING IN MEDICINE AND SURGERY J2 - QUANT IMAG MED SURG (QUIMS) VL - 13 PY - 2023 IS - 1 SP - 320 EP - 328 PG - 9 SN - 2223-4292 DO - 10.21037/qims-22-417 UR - https://m2.mtmt.hu/api/publication/33262894 ID - 33262894 N1 - Funding Agency and Grant Number: Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund; TKP2021-EGA funding scheme; [TKP2021-EGA-20] Funding text: The abstract of the manuscript has been presented on the 2021 congress of the European Society of Cardiology. Funding: Project no. TKP2021-EGA-20 has been implemented with the support provided by the Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund, financed under the TKP2021-EGA funding scheme. AB - Background: Earlier results suggest the role of speckle-tracking echocardiography (STE)-derived left ventricular (LV) strains in screening and could help better understanding of adaptation to exercise. The present retrospective cohort study aimed to investigate three-dimensional STE-derived LV strains representing its deformation in athletes playing sports with high dynamics with different grades of static components of their training. Methods. The study consisted of 67 athletes (mean age: 23.6±6.4 years, 39 males). This group of athletes was further divided into the following groups: Group C.I. (high dynamic/low static) (n=12), Group C.II. (high dynamic/moderate static) (n=22) and Group C.III. (high dynamic/high static) (n=33). The control group comprised 83 age- and gender-matched non-athletic healthy volunteers (mean age: 23.6±3.2 years, 50 males). Results: Global LV longitudinal strain (LS) representing LV lengthening or shortening (-18.5%±3.0% vs. -16.3%±2.3%, P<0.05), LV circumferential strain (CS) representing LV widening or narrowing (-29.9%±5.2% vs. -28.1%±4.8%, P<0.05) and LV area strain (AS; combination of LS and CS; -43.7%±5.4% vs. -40.9%±4.8%, P<0.05) were increased in elite athletes as compared to those of non-athlete controls. All apical LV strains proved to be increased in all athletes with enhanced basal radial strain (RS, representing LV thickening and thinning) and LS and midventricular LS, AS and 3D strain (3DS, combination of RS, LS and CS). Conclusions: Increased LV-LS, LV-CS and LV-AS represents enhanced LV deformation in longitudinal and circumferential directions in athletes playing sports with high dynamics. This enhancement is not related to the grade of the static component of training. Some regional differences in LV strains could be detected. LA - English DB - MTMT ER - TY - CONF AU - Varga, Árpád AU - Görög, Marietta AU - Madácsy, Tamara AU - Pallagi, Petra AU - Szabó, Viktória AU - Kiss, Aletta Kata AU - Susánszki, Petra AU - Jójárt, Boldizsár AU - Tél, Bálint AU - Balázs, Anita AU - Farkas, Gyula Jr. AU - Szederkényi, Edit AU - Lázár, György ifj AU - Maléth, József TI - CFTR activity is determined by the store-independent activation of SPCA2/STIM1/ORAI1 complex in secretory epithelial cells T2 - European Cystic Fibrosis Society 17th ECFS Basic Science Conference C1 - Albufeira PY - 2022 SP - 56 UR - https://m2.mtmt.hu/api/publication/34657311 ID - 34657311 LA - English DB - MTMT ER - TY - THES AU - Szalóki, Tibor TI - The value of indigo carmine staining in endoscopy and endoscopic mucosal resection in the human stomach PB - Szegedi Tudományegyetem (SZTE) PY - 2008 SP - 43 UR - https://m2.mtmt.hu/api/publication/30793668 ID - 30793668 LA - English DB - MTMT ER - TY - THES AU - Venglovecz, Viktória TI - Examination of primary epithelial cells under normal and pathophysiological conditions PB - Szegedi Tudományegyetem (SZTE) PY - 2008 SP - 52 UR - https://m2.mtmt.hu/api/publication/23164513 ID - 23164513 LA - English DB - MTMT ER - TY - THES AU - Ózsvári, Béla TI - The role of trypsin and bile acids in acute and chronic pancreatitis PB - Szegedi Tudományegyetem (SZTE) PY - 2008 SP - 50 UR - https://m2.mtmt.hu/api/publication/20753649 ID - 20753649 LA - English DB - MTMT ER - TY - THES AU - Farkas, Gyula Jr. TI - The essence of cytokines from experimental acute pancreatitis through organ preserving pancreatic head resection PB - Szegedi Tudományegyetem (SZTE) PY - 2008 SP - 50 UR - https://m2.mtmt.hu/api/publication/2430896 ID - 2430896 LA - English DB - MTMT ER - TY - JOUR AU - Ignath, I AU - Rakonczay, Zoltán AU - Takács, Tamás AU - Schnúr, Andrea AU - Venglovecz, Viktória AU - Szepes, A AU - Szepes, Zoltán AU - Czakó, László AU - Tiszai, Andrea AU - Rosztóczy, András AU - Molnár, Tamás AU - Izbéki, Ferenc AU - Lonovics, János AU - Varró, András AU - Hegyi, Péter TI - Characterization of acid/base transporters in parietal cells isolated from human gastric biopsy samples JF - ZEITSCHRIFT FÜR GASTROENTEROLOGIE J2 - Z GASTROENTEROL VL - 45 PY - 2007 SP - 431 PG - 1 SN - 0044-2771 DO - 10.1055/s-2007-982669 UR - https://m2.mtmt.hu/api/publication/1249452 ID - 1249452 LA - English DB - MTMT ER - TY - JOUR AU - Tóth-Molnár, Edit AU - Venglovecz, Viktória AU - Ózsvári, Béla AU - Rakonczay, Zoltán AU - Varró, András AU - Papp, Gyula AU - Tóth, András AU - Lonovics, János AU - Takács, Tamás AU - Ignáth, Imre AU - Iványi, Béla AU - Hegyi, Péter TI - New experimental method to study acid/base transporters and their regulation in lacrimal gland ductal epithelia JF - INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE J2 - INVEST OPHTH VIS SCI VL - 48 PY - 2007 IS - 8 SP - 3746 EP - 3755 PG - 10 SN - 0146-0404 DO - 10.1167/iovs.06-1291 UR - https://m2.mtmt.hu/api/publication/1132580 ID - 1132580 N1 - * Megosztott szerzőség AB - PURPOSE. The main function of the lacrimal gland is to produce the most aqueous component of the tear film covering the surfaces of the cornea and the conjunctiva. Studies have been conducted that characterize the mixed fluid and protein secretion of isolated acini, but no methods have been developed to characterize lacrimal gland ductal cell (LGDC) secretion. Secretory mechanisms of ductal epithelia may play physiological roles in the maintenance of the standard environments for the cornea and the conjunctiva. METHODS. In this study, the authors developed a rapid method to isolate large quantities of intact lacrimal ducts. The preparation of isolated intact lacrimal gland ducts for the first time enabled the performance of real-time functional experiments on cleaned ducts. Electron microscopy and fluorescence measurements were used to evaluate the viability of lacrimal ducts. RESULTS. Fluorescence measurements showed that LGDCs express functionally active Na+/H+ exchanger (NHE) and Cl+/HCO3- exchanger (AE). Parasympathomimetic stimulation by carbachol stimulated NHE and AE through the elevation of intracellular calcium concentration. This mechanism can play a role in the regulation of ion and water secretion by LGDCs. CONCLUSIONS. The authors have described a lacrimal gland duct isolation technique in which the intact ducts remain viable and the role of duct cells in tear film secretion can be characterized. These data combined with the novel isolation facilitated understanding of the regulation mechanisms of ductal cell secretion at cellular and molecular levels under normal and pathologic conditions. LA - English DB - MTMT ER - TY - JOUR AU - Czakó, László AU - Szabolcs, Annamária AU - Vajda, A AU - Csáti, S AU - Venglovecz, Viktória AU - Rakonczay, Zoltán AU - Hegyi, Péter AU - Tiszlavicz, László AU - Csont, Tamás Bálint AU - Pósa, Anikó AU - Magyariné, Berkó Anikó AU - Varga, Csaba AU - Szőllősi Varga, Ilona AU - Boros, Imre Miklós AU - Lonovics, János TI - Hyperlipidemia induced by a cholesterol-rich diet aggravates necrotizing pancreatitis in rats JF - EUROPEAN JOURNAL OF PHARMACOLOGY J2 - EUR J PHARMACOL VL - 572 PY - 2007 IS - 1 SP - 74 EP - 81 PG - 8 SN - 0014-2999 DO - 10.1016/j.ejphar.2007.05.064 UR - https://m2.mtmt.hu/api/publication/1129064 ID - 1129064 LA - English DB - MTMT ER - TY - JOUR AU - Börcsök, É AU - Várkonyi, Tamás AU - Takács, Róbert AU - Róka, Richárd László AU - Lengyel, Csaba Attila AU - Lázár, M AU - Papós, Miklós AU - Pávics, László AU - Kempler, Péter AU - Lonovics, János TI - Az autonóm és szenzoros neuropathia, valamint a gyomorürülés jellemzőinek összevetése rövid és hosszú ideje fennálló 1-es típusú diabetesben JF - MAGYAR BELORVOSI ARCHIVUM J2 - MBA VL - 59 PY - 2006 IS - Suppl.4 SP - 49 EP - 51 PG - 3 SN - 0133-5464 UR - https://m2.mtmt.hu/api/publication/1329472 ID - 1329472 LA - Hungarian DB - MTMT ER -