TY  - JOUR
AU  - Sira, Lívia
AU  - Zsíros, Noémi
AU  - Bidiga, László
AU  - Barna, Sándor Kristóf
AU  - Kanyári, Zsolt
AU  - Nagy, Edit B.
AU  - Guillaume, Nicolas
AU  - Wild, Damian
AU  - Rázsó, Katalin
AU  - Andó, Szilvia
AU  - Balogh, István
AU  - Nagy, Endre
AU  - Balogh, Zoltán
TI  - Case report: Metastatic pancreatic neuroendocrine tumour associated with portal vein thrombosis; successful management with subsequent pregnancies
JF  - FRONTIERS IN ENDOCRINOLOGY
J2  - FRONT ENDOCRINOL
VL  - 14
PY  - 2023
PG  - 7
SN  - 1664-2392
DO  - 10.3389/fendo.2023.1095815
UR  - https://m2.mtmt.hu/api/publication/33699902
ID  - 33699902
AB  - Background: Splanchnic vein thrombosis due to co-existing metastatic pancreatic neuroendocrine tumour (pNET) and JAK2V617F mutation is a rare condition. Case report: Here we present a case of a young woman with complete remission of a non-functioning grade 2 pNET with unresectable liver metastases, coexisting with JAK2V617F mutation. Splenectomy and distal pancreatectomy were performed. Neither surgical removal, nor radiofrequency ablation of the liver metastases was possible. Therefore, somatostatin analogue (SSA) and enoxaparine were started. Peptide receptor radionuclide therapy (PRRT) was given in 3 cycles 6-8 weeks apart. Genetic testing revealed no multiple endocrine neoplasia type 1 (MEN-1) gene mutations. After shared decision making with the patient, she gave birth to two healthy children, currently 2 and 4 years old. On pregnancy confirmation, SSA treatment was interrupted and resumed after each delivery. Ten years after the diagnosis of pNET, no tumour is detectable by MRI or somatostatin receptor scintigraphy. PRRT followed by continuous SSA therapy, interrupted only during pregnancies, resulted in complete remission and enabled the patient to complete two successful pregnancies.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Zsíros, Noémi
AU  - Paragh, György
AU  - Balogh, István
AU  - Harangi, Mariann
TI  - A MODY jelentősége a diabéteszes betegek ellátásában: irodalmi áttekintés egy eset kapcsán
JF  - METABOLIZMUS
J2  - METABOLIZMUS
VL  - 20
PY  - 2022
IS  - 2
SP  - 51
EP  - 58
PG  - 8
SN  - 1589-7311
UR  - https://m2.mtmt.hu/api/publication/32815076
ID  - 32815076
LA  - Hungarian
DB  - MTMT
ER  -