@article{MTMT:33699902, title = {Case report: Metastatic pancreatic neuroendocrine tumour associated with portal vein thrombosis; successful management with subsequent pregnancies}, url = {https://m2.mtmt.hu/api/publication/33699902}, author = {Sira, Lívia and Zsíros, Noémi and Bidiga, László and Barna, Sándor Kristóf and Kanyári, Zsolt and Nagy, Edit B. and Guillaume, Nicolas and Wild, Damian and Rázsó, Katalin and Andó, Szilvia and Balogh, István and Nagy, Endre and Balogh, Zoltán}, doi = {10.3389/fendo.2023.1095815}, journal-iso = {FRONT ENDOCRINOL}, journal = {FRONTIERS IN ENDOCRINOLOGY}, volume = {14}, unique-id = {33699902}, issn = {1664-2392}, abstract = {Background: Splanchnic vein thrombosis due to co-existing metastatic pancreatic neuroendocrine tumour (pNET) and JAK2V617F mutation is a rare condition. Case report: Here we present a case of a young woman with complete remission of a non-functioning grade 2 pNET with unresectable liver metastases, coexisting with JAK2V617F mutation. Splenectomy and distal pancreatectomy were performed. Neither surgical removal, nor radiofrequency ablation of the liver metastases was possible. Therefore, somatostatin analogue (SSA) and enoxaparine were started. Peptide receptor radionuclide therapy (PRRT) was given in 3 cycles 6-8 weeks apart. Genetic testing revealed no multiple endocrine neoplasia type 1 (MEN-1) gene mutations. After shared decision making with the patient, she gave birth to two healthy children, currently 2 and 4 years old. On pregnancy confirmation, SSA treatment was interrupted and resumed after each delivery. Ten years after the diagnosis of pNET, no tumour is detectable by MRI or somatostatin receptor scintigraphy. PRRT followed by continuous SSA therapy, interrupted only during pregnancies, resulted in complete remission and enabled the patient to complete two successful pregnancies.}, year = {2023}, eissn = {1664-2392} } @article{MTMT:32815076, title = {A MODY jelentősége a diabéteszes betegek ellátásában: irodalmi áttekintés egy eset kapcsán}, url = {https://m2.mtmt.hu/api/publication/32815076}, author = {Zsíros, Noémi and Paragh, György and Balogh, István and Harangi, Mariann}, journal-iso = {METABOLIZMUS}, journal = {METABOLIZMUS}, volume = {20}, unique-id = {32815076}, issn = {1589-7311}, year = {2022}, pages = {51-58} }