@article{MTMT:34406348, title = {Thermodynamic Characterization of the Interaction of Biofunctionalized Gold Nanoclusters with Serum Albumin Using Two- and Three-Dimensional Methods}, url = {https://m2.mtmt.hu/api/publication/34406348}, author = {Juhász, Ádám and Gombár, Gyöngyi and F. Várkonyi, Egon and Wojnicki, Marek and Ungor, Ditta Anita and Csapó, Edit}, doi = {10.3390/ijms242316760}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {24}, unique-id = {34406348}, issn = {1661-6596}, abstract = {Fluorescent gold nanoclusters have been successfully used as fluorescent markers for imaging of cells and tissues, and their potential role in drug delivery monitoring is coming to the fore. In addition, the development of biosensors using structure-tunable fluorescent nanoclusters is also a prominent research field. In the case of these sensor applications, the typical goal is the selective identification of, e.g., metal ions, small molecules having neuroactive or antioxidant effects, or proteins. During these application-oriented developments, in general, there is not enough time to systematically examine the interaction between nanoclusters and relevant biomolecules/proteins from a thermodynamic viewpoint. In this way, the primary motivation of this article is to carry out a series of tests to partially fill this scientific gap. Besides the well-known fluorescent probes, the mentioned interactions were investigated using such unique measurement methods as surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC). These two-dimensional (at the solid/liquid interface) and three-dimensional (in the bulk phase) measuring techniques provide a unique opportunity for the thermodynamic characterization of the interaction between different gold nanoclusters containing various surface functionalizing ligands and bovine serum albumin (BSA).}, year = {2023}, eissn = {1422-0067}, orcid-numbers = {Juhász, Ádám/0000-0003-0033-7968; Wojnicki, Marek/0000-0002-1387-0000; Ungor, Ditta Anita/0000-0002-7659-0428; Csapó, Edit/0000-0002-6980-9524} } @article{MTMT:34393301, title = {Revisiting the hydrolysis of ampicillin catalyzed by Temoneira-1 β-lactamase, and the effect of Ni(II), Cd(II) and Hg(II)}, url = {https://m2.mtmt.hu/api/publication/34393301}, author = {Nafaee, Zeyad Hasan Abdullah and Egyed, Viktória and Jancsó, Attila and Tóth, Annamária and Gerami, Adeleh Mokhles and Dang, Thanh Thien and Heiniger-Schell, Juliana and Hemmingsen, Lars and Hunyadi-Gulyás Éva, Csilla and Peintler, Gábor and Gyurcsik, Béla}, doi = {10.1002/pro.4809}, journal-iso = {PROTEIN SCI}, journal = {PROTEIN SCIENCE}, volume = {32}, unique-id = {34393301}, issn = {0961-8368}, abstract = {Abstract ?-Lactamases grant resistance to bacteria against ?-lactam antibiotics. The active center of TEM-1 ?-lactamase accommodates a Ser-Xaa-Xaa-Lys motif. TEM-1 ?-lactamase is not a metalloenzyme but it possesses several putative metal ion binding sites. The sites composed of His residue pairs chelate borderline transition metal ions such as Ni(II). In addition, there are many sulfur-containing donor groups that can coordinate soft metal ions such as Hg(II). Cd(II) may bind to both types of the above listed donor groups. No significant change was observed in the circular dichroism spectra of TEM-1 ?-lactamase on increasing the metal ion content of the samples, with the exception of Hg(II) inducing a small change in the secondary structure of the protein. A weak nonspecific binding of Hg(II) was proven by mass spectrometry and 119mHg perturbed angular correlation spectroscopy. The hydrolytic process of ampicillin catalyzed by TEM-1 ?-lactamase was described by the kinetic analysis of the set of full catalytic progress curves, where the slow, yet observable conversion of the primary reaction product into a second one, identified as ampilloic acid by mass spectrometry, needed also to be considered in the applied model. Ni(II) and Cd(II) slightly promoted the catalytic activity of the enzyme while Hg(II) exerted a noticeable inhibitory effect. Hg(II) and Ni(II), applied at 10??M concentration, inhibited the growth of E. coli BL21(DE3) in M9 minimal medium in the absence of ampicillin, but addition of the antibiotic could neutralize this toxic effect by complexing the metal ions.}, keywords = {Mass spectrometry; Circular Dichroism; Reaction kinetics; 199mHg perturbed angular correlation spectroscopy of γ-rays; TEM-1 β-lactamase; toxic metal binding}, year = {2023}, eissn = {1469-896X}, orcid-numbers = {Jancsó, Attila/0000-0003-2362-0758; Peintler, Gábor/0000-0001-5171-5346; Gyurcsik, Béla/0000-0003-1894-7414} } @article{MTMT:34158958, title = {Photoelectrochemical hydrogen evolution on macroscopic electrodes of exfoliated SnSe flakes}, url = {https://m2.mtmt.hu/api/publication/34158958}, author = {Ba, Qianqian and Tóth, Péter Sándor and Vass, Ádám and Rajeshwar, Krishnan and Janáky, Csaba}, doi = {10.1016/j.apcata.2023.119233}, journal-iso = {APPL CATAL A-GEN}, journal = {APPLIED CATALYSIS A-GENERAL}, volume = {661}, unique-id = {34158958}, issn = {0926-860X}, year = {2023}, eissn = {1873-3875}, orcid-numbers = {Janáky, Csaba/0000-0001-5965-5173} } @mastersthesis{MTMT:34120545, title = {Foszforeszcens stroncium-aluminátok előállítása és fejlesztése [Synthesis and development of phosphorescent Strontium-aluminates]}, url = {https://m2.mtmt.hu/api/publication/34120545}, author = {Havasi, Viktor}, doi = {10.14232/phd.11259}, publisher = {Universití of Szeged}, unique-id = {34120545}, abstract = {A fény az emberiség életében a központi szerepet betöltő tényezők közé tartozik, éppen ezért a különböző természetes fényjelenségek és a fényjelenségeket mutató anyagok a történelmi idők kezdete óta foglalkoztatják az emberiséget. Ezen jelenségek és anyagok megértésére és leutánzására számtalan kísérlet történt és történik napjainkban is. Ma már lehetőségünk van szinte bármely természetben előforduló jelenség vagy anyag utánzására, vizsgálatára és a jelenségek modellezésére, így a fényjelenségekkel és a fényjelenségeket mutató anyagokkal kapcsolatos ismereteink bővítésére is. Ennek ellenére egyes jelenségek működése a mai napig is csak részben ismeretes, megértésük folyamatosan zajlik. A folyamatosan fejlesztett új anyagok új tulajdonságai fokozatosan analógiákra világítanak rá, így segítve a tapasztalt jelenségek mélyebb megértését is. A különböző lumineszcencia típusok között a foszforeszcencia az egyik legkomplexebb módon lejátszódó jelenség, amelyben az egyes részfolyamatok és azok szerepei még mindig csak részben tisztázottak. Mai tudásunkkal így is már előre tervezhetünk is olyan lumineszcens anyagokat, amelyek az igényeinknek leginkább megfelelnek. Ezek az igények széleskörűen változhatnak a felhasználás módjától függően, így szükséges lehet szélsőségesen hosszú, vagy éppen rövid utánvilágítási idővel rendelkező anyagokra, a kibocsájtott és elnyelt hullámhosszak manipulációja. A zöld szemlélet előretörésével, a lumineszcens anyagokkal szemben olyan új igények fogalmazódtak meg, mint a hosszú élettartam, az újrafelhasználhatóság, extrém kémiai és fizikai stabilitás, biztonságosabb felhasználhatóság vagy egyszerűen csak az olcsó és nagy volumenű előállíthatóság. Ezek biztosítása érdekében az új igényekhez új anyagok fejleszthetők, vagy régi anyagok továbbfejleszthetőek, az ismert anyagokhoz pedig új alkalmazásmódok társíthatóak. Napjainkban számos aktivált fotolumineszcens szervetlen oxidot ismerünk, melyek közül csak néhány példa: MAl2O4, M4Al14O25 M2ZnSiO7, MAlSiN3, MBPO5, M3PO4 (M = Mg, Ca, Sr, Ba). A szennyező (aktiváló/ko-aktiváló) ionok jelenléte általában szükséges; ezek a befogadó kristályszerkezettől függően egy vagy többféle ritkaföldfém, de átmeneti fém is lehetnek. Ezen anyagok egyik legnagyobb előnye a tartósságuk mellett az, hogy nem tartalmaznak radioaktív összetevőt. Azonban, a több száz ismert foszforeszcens anyagból csupán néhány képes napfényen is feltöltődni, majd órákig fényt kibocsájtani, ezért az erre együttesen képes anyagok különleges figyelmet élveznek.}, year = {2023} } @mastersthesis{MTMT:34120485, title = {Cinkujj fehérjék fémion-, és DNS-kötésének vizsgálata, módosításuk Ni(II)-indukált peptidhidrolízis segítségével [Investigation of metal ion and DNA binding of zinc finger proteins, modification by Ni(II)-induced peptide hydrolysis]}, url = {https://m2.mtmt.hu/api/publication/34120485}, author = {Hajdu, Bálint}, doi = {10.14232/phd.11642}, publisher = {Universití of Szeged}, unique-id = {34120485}, year = {2023} } @mastersthesis{MTMT:34120416, title = {Copper(II) and (η 5 -Cp*)rhodium(III) complexes of some imidazole and pyridine containing ligands}, url = {https://m2.mtmt.hu/api/publication/34120416}, author = {Hassoon, Azza Ahmed Mousad Megahed}, doi = {10.14232/phd.11585}, publisher = {Universití of Szeged}, unique-id = {34120416}, year = {2023} } @article{MTMT:34071578, title = {Hydrolytic Mechanism of a Metalloenzyme Is Modified by the Nature of the Coordinated Metal Ion}, url = {https://m2.mtmt.hu/api/publication/34071578}, author = {Nafaee, Zeyad Hasan Abdullah and Hajdu, Bálint and Hunyadi-Gulyás Éva, Csilla and Gyurcsik, Béla}, doi = {10.3390/molecules28145511}, journal-iso = {MOLECULES}, journal = {MOLECULES}, volume = {28}, unique-id = {34071578}, issn = {1420-3049}, abstract = {The nuclease domain of colicin E7 cleaves double-strand DNA non-specifically. Zn2+ ion was shown to be coordinated by the purified NColE7 as its native metal ion. Here, we study the structural and catalytic aspects of the interaction with Ni2+, Cu2+ and Cd2+ non-endogenous metal ions and the consequences of their competition with Zn2+ ions, using circular dichroism spectroscopy and intact protein mass spectrometry. An R447G mutant exerting decreased activity allowed for the detection of nuclease action against pUC119 plasmid DNA via agarose gel electrophoresis in the presence of comparable metal ion concentrations. It was shown that all of the added metal ions could bind to the apoprotein, resulting in a minor secondary structure change, but drastically shifting the charge distribution of the protein. Zn2+ ions could not be replaced by Ni2+, Cu2+ and Cd2+. The nuclease activity of the Ni2+-bound enzyme was extremely high in comparison with the other metal-bound forms, and could not be inhibited by the excess of Ni2+ ions. At the same time, this activity was significantly decreased in the presence of equivalent Zn2+, independent of the order of addition of each component of the mixture. We concluded that the Ni2+ ions promoted the DNA cleavage of the enzyme through a more efficient mechanism than the native Zn2+ ions, as they directly generate the nucleophilic OH− ion.}, year = {2023}, eissn = {1420-3049}, orcid-numbers = {Hajdu, Bálint/0000-0003-4024-116X; Hunyadi-Gulyás Éva, Csilla/0000-0003-2089-1499; Gyurcsik, Béla/0000-0003-1894-7414} } @article{MTMT:33911573, title = {Photoelectrochemistry of two-dimensional and layered materials: a brief review}, url = {https://m2.mtmt.hu/api/publication/33911573}, author = {Tóth, Péter Sándor and Ba, Qianqian and Janáky, Csaba}, doi = {10.1007/s10008-023-05503-z}, journal-iso = {J SOLID STATE ELECTR}, journal = {JOURNAL OF SOLID STATE ELECTROCHEMISTRY}, volume = {27}, unique-id = {33911573}, issn = {1432-8488}, abstract = {Two-dimensional (2D) materials have unique band structure and show a great promise for optoelectronic and solar energy harvesting applications. Photoelectrochemical (PEC) processes are intensively studied employing these materials, due to their high specific surface area, and the possibility of surface modification by defect engineering/catalyst deposition. The PEC activity of different 2D and layered materials was scrutinized for water oxidation/reduction and for inorganic ion oxidation by a statistical analysis to reveal any specific trends. Furthermore, some frequently studied performance improvement strategies (i.e., heterojunctions, tunnelling, and co-catalysts) are also discussed. Overall, exploring novel materials of 2D family, and new directions are both needed to initiate further discussions and additional research activity, which might enable to harness the full potential of these exciting materials.}, keywords = {Chalcogenides; Heterojunction; Light harvesting; Photoelectrocatalysis; Nanoflakes}, year = {2023}, eissn = {1433-0768}, pages = {1701-1715}, orcid-numbers = {Janáky, Csaba/0000-0001-5965-5173} } @article{MTMT:33763892, title = {Sustainable synthesis of azobenzenes, quinolines and quinoxalines via oxidative dehydrogenative couplings catalysed by reusable transition metal oxide–Bi( iii ) cooperative catalysts}, url = {https://m2.mtmt.hu/api/publication/33763892}, author = {Kocsis, Marianna and Baán, Kornélia and Ötvös, Sándor Balázs and Kukovecz, Ákos and Kónya, Zoltán and Sipos, Pál Miklós and Pálinkó, István and Varga, Gábor}, doi = {10.1039/D3CY00327B}, journal-iso = {CATAL SCIENCE & TECHNOLOGY}, journal = {CATALYSIS SCIENCE & TECHNOLOGY}, volume = {13}, unique-id = {33763892}, issn = {2044-4753}, abstract = {Heterogeneous catalytic oxidative dehydrogenative processes for N-heterocycles are presented, which enable waste-minimized (additive-, oxidant-, base-free), efficient cyclisations/couplings via transition metal oxide–Bi( iii ) cooperative catalysis.}, year = {2023}, eissn = {2044-4761}, pages = {3069-3083}, orcid-numbers = {Baán, Kornélia/0000-0001-7511-4422; Ötvös, Sándor Balázs/0000-0001-6673-1744; Kukovecz, Ákos/0000-0003-0716-9557; Kónya, Zoltán/0000-0002-9406-8596; Sipos, Pál Miklós/0000-0003-1407-0950; Pálinkó, István/0000-0002-8508-309X; Varga, Gábor/0000-0002-7131-1629} } @article{MTMT:33735013, title = {Vertical π-extension of dibenzopentalene: a combined experimental and computational study of a phenanthreno-benzopentalene derivative}, url = {https://m2.mtmt.hu/api/publication/33735013}, author = {Mayer, Péter József and Botlik, Bence B. and Meiszter, Enikő and Németh, Krisztina and Schürmann, Christian J. and Holczbauer, Tamás and London, Gábor}, doi = {10.1016/j.comptc.2023.114113}, journal-iso = {COMPUT THEOR CHEM}, journal = {COMPUTATIONAL AND THEORETICAL CHEMISTRY}, volume = {1224}, unique-id = {33735013}, issn = {2210-271X}, year = {2023}, eissn = {2210-2728} }