@article{MTMT:34759290,
	title = {Investigating Vα7.2+/CD161− T Cell and MAIT Cell Profiles Using Flow Cytometry in Healthy Subjects and Subjects with Atopic Dermatitis},
	url = {https://m2.mtmt.hu/api/publication/34759290},
	author = {Parvind, Singh and Gáspár, Krisztián and Szegedi, Andrea and Sajtos, Laszlo and Baráth, Sándor and Hevessy Zsuzsanna, Dóra},
	doi = {10.3390/ijms25063486},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34759290},
	issn = {1661-6596},
	abstract = {This study investigates the roles of mucosal-associated invariant T (MAIT) cells and Vα7.2+/CD161− T cells in skin diseases, focusing on atopic dermatitis. MAIT cells, crucial for bridging innate and adaptive immunity, were analyzed alongside Vα7.2+/CD161− T cells in peripheral blood samples from 14 atopic dermatitis patients and 10 healthy controls. Flow cytometry and machine learning algorithms were employed for a comprehensive analysis. The results indicate a significant decrease in MAIT cells and CD69 subsets in atopic dermatitis, coupled with elevated CD38 and polyfunctional MAIT cells producing TNFα and Granzyme B (TNFα+/GzB+). Vα7.2+/CD161− T cells in atopic dermatitis exhibited a decrease in CD8 and IFNγ-producing subsets but an increase in CD38 activated and IL-22-producing subsets. These results highlight the distinctive features of MAIT cells and Vα7.2+/CD161− T cells and their different roles in the pathogenesis of atopic dermatitis and provide insights into their potential roles in immune-mediated skin diseases.},
	year = {2024},
	eissn = {1422-0067},
	pages = {3486}
}

@article{MTMT:34496858,
	title = {Get reliable laboratory findings – how to recognize the deceptive effects of angiotensin-converting enzyme inhibitor therapy in the laboratory diagnostics of sarcoidosis?},
	url = {https://m2.mtmt.hu/api/publication/34496858},
	author = {Szabó, Attila Ádám and Enyedi, Enikő Edit and Altorjay, István and Hajnal, Péter and Pintér, Tamás Bence and Mányiné Siket, Ivetta and Váradi, Csongor and Bányai, Emese and Tóth, Attila and Papp, Zoltán and Fagyas, Miklós},
	doi = {10.1515/cclm-2023-1288},
	journal-iso = {CLIN CHEM LAB MED},
	journal = {CLINICAL CHEMISTRY AND LABORATORY MEDICINE},
	unique-id = {34496858},
	issn = {1434-6621},
	abstract = {Objectives
		Serum angiotensin-converting enzyme (ACE) is the only biomarker routinely used in the laboratory diagnostics of sarcoidosis, and ACE inhibitor (ACEi) drugs are among the most prescribed drugs worldwide. Taking ACEi can mislead medical teams by lowering ACE activity, delaying diagnosis and giving a false impression of disease activity of sarcoidosis. We aimed to develop a simple method to detect the presence of ACEi drugs in samples, to investigate the ACEi medication-caused interference and consequences in a retrospective study.
		
		Methods
		ACE activity and the level of ACE inhibition were determined for 1823 patients with suspected sarcoidosis. These values were compared with the therapeutic information at the first and follow-up visits.
		
		Results
		A total of 302 patients had biochemical evidence of an ACEi drug effect during diagnostic ACE activity testing. In their case, ACE activity was significantly lower (median(IQR): 4.41 U/L(2.93–6.72)) than in patients not taking ACEi (11.32 U/L(8.79–13.92), p<0.01). In 62 sarcoidosis patients, the ACEi reduced ACE activity to the reference range or below. Only in 40 % of the cases was the medication list recorded in the outpatient chart and only in 3 cases was low ACE activity associated with ACEi use. 67 % of the repeated ACE activity measurements were also performed during ACEi therapy.
		
		Conclusions
		Our study revealed that the use of ACEi is common in patients with suspected sarcoidosis. The ACE activity lowering effect of ACEi drugs may escape the attention of medical teams which can lead to diagnostic errors and unnecessary tests. Nevertheless, these pitfalls can be avoided by using a method suggested by our team.},
	year = {2024},
	eissn = {1437-4331},
	orcid-numbers = {Váradi, Csongor/0000-0001-7332-1524; Fagyas, Miklós/0000-0003-3262-884X}
}

@article{MTMT:34441776,
	title = {Low factor XIII levels and altered fibrinolysis in patients with multiple myeloma},
	url = {https://m2.mtmt.hu/api/publication/34441776},
	author = {Harriet, Ghansah and Orbán-Kálmándi, Rita Angéla and Bekéné Debreceni, Ildikó and Katona, Éva and Rejtő, László and Váróczy, László and Lóczi, Linda and de Laat, Bas and Huskens, Dana and Kappelmayer, János and Bagoly, Zsuzsa},
	doi = {10.1016/j.thromres.2023.12.004},
	journal-iso = {THROMB RES},
	journal = {THROMBOSIS RESEARCH},
	volume = {234},
	unique-id = {34441776},
	issn = {0049-3848},
	year = {2024},
	eissn = {1879-2472},
	pages = {12-20},
	orcid-numbers = {Orbán-Kálmándi, Rita Angéla/0000-0002-2155-8279; Katona, Éva/0000-0003-3476-794X; Bagoly, Zsuzsa/0000-0001-5314-5607}
}

@article{MTMT:34769050,
	title = {The impact of a complete biochemical response on health-related quality of life in patients with autoimmune hepatitis: a multicentre prospective cross-sectional study},
	url = {https://m2.mtmt.hu/api/publication/34769050},
	author = {Snijders, Romee and Janik, Maciej K. and Mund, Meike and Gerussi, Alessio and Bolis, Francesca and Cristoferi, Laura and Invernizzi, Pietro and Kováts, Patrícia and Papp, Mária and Gronbaek, Lisbet and Gronbaek, Henning and Tjwa, E. T. T. L. and Aamann, Luise and Ytting, Henriette and Ronca, Vincenzo and Olsen, Katheryn and Oo, Ye Htun and Van, der Meer Adriaan and Madaleno, Joao and Canhao, Bernardo and Engel, Bastian and Campos-Murguia, Alejandro and Taubert, Richard and Koc, Ozgur and Kramer, Matthijs and Willemse, Jose and Loewe, Bernd and Lohse, Ansgar W. and Drenth, Joost P. H. and Schramm, Christoph and Milkiewicz, Piotr and Gevers, Tom},
	journal-iso = {J HEPATOL},
	journal = {JOURNAL OF HEPATOLOGY},
	volume = {78},
	unique-id = {34769050},
	issn = {0168-8278},
	year = {2023},
	eissn = {1600-0641},
	pages = {S982-S982},
	orcid-numbers = {Papp, Mária/0000-0003-3662-4010}
}

@article{MTMT:34768346,
	title = {Results of the prospective multicentre European R-LIVER registry reveal the unmet clinical needs of autoimmune hepatitis},
	url = {https://m2.mtmt.hu/api/publication/34768346},
	author = {Schregel, Ida and Papp, Mária and Sipeki, Nóra and Kováts, Patrícia and Taubert, Richard and Engel, Bastian and Campos-Murguia, Alejandro and Dalekos, George and Gatselis, Nikolaos and Zachou, Kalliopi and Milkiewicz, Piotr and Janik, Maciej K. and Raszeja-Wyszomirska, Joanna and Ytting, Henriette and Braun, Felix and Casar, Christian and Lohse, Ansgar W. and Schramm, Christoph},
	journal-iso = {J HEPATOL},
	journal = {JOURNAL OF HEPATOLOGY},
	volume = {78},
	unique-id = {34768346},
	issn = {0168-8278},
	year = {2023},
	eissn = {1600-0641},
	pages = {S45-S46},
	orcid-numbers = {Papp, Mária/0000-0003-3662-4010; Sipeki, Nóra/0000-0002-6806-2991}
}

@article{MTMT:34395283,
	title = {Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review},
	url = {https://m2.mtmt.hu/api/publication/34395283},
	author = {Kest, Michael and Ágoston, András and Szabó, Gábor Tamás and Kiss, Attila and Üveges, Áron and Czuriga, Dániel and Komócsi, András and Hizoh, István and Kőszegi, Zsolt},
	doi = {10.1007/s00392-023-02338-6},
	journal-iso = {CLIN RES CARDIOL},
	journal = {CLINICAL RESEARCH IN CARDIOLOGY},
	volume = {In press},
	unique-id = {34395283},
	issn = {1861-0684},
	year = {2023},
	eissn = {1861-0692},
	pages = {In press},
	orcid-numbers = {Czuriga, Dániel/0000-0002-6972-0781; Hizoh, István/0000-0001-5141-2070}
}

@article{MTMT:34394226,
	title = {A Microsurgical Arteriovenous Malformation Model on Saphenous Vessels in the Rat},
	url = {https://m2.mtmt.hu/api/publication/34394226},
	author = {Al-Smadi, Mohammad and Fazekas, László Ádám and Aslan, Siran and Bernát, Brigitta Renáta and Beqain, Anas and Al-Khafaji, Mustafa Qais Muhsin and Priksz, Dániel and Orlik, Brigitta and Németh, Norbert},
	doi = {10.3390/biomedicines11112970},
	journal-iso = {BIOMEDICINES},
	journal = {BIOMEDICINES},
	volume = {11},
	unique-id = {34394226},
	abstract = {Arteriovenous malformation (AVM) is an anomaly of blood vessel formation. Numerous models have been established to understand the nature of AVM. These models have limitations in terms of the diameter of the vessels used and the impact on the circulatory system. Our goal was to establish an AVM model that does not cause prompt and significant hemodynamic and cardiac alterations but is feasible for follow-up of the AVM’s progression. Sixteen female rats were randomly divided into sham-operated and AVM groups. In the AVM group, the saphenous vein and artery were interconnected using microsurgical techniques. The animals were followed up for 12 weeks. Anastomosis patency and the structural and hemodynamic changes of the heart were monitored. The hearts and vessels were histologically analyzed. During the follow-up period, shunts remained unobstructed. Systolic, diastolic, mean arterial pressure, and heart rate values slightly and non-significantly decreased in the AVM group. Echocardiogram results indicated minor systolic function impact, with slight and insignificant changes in aortic pressure and blood velocity, and minimal left ventricular wall enlargement. The small-caliber saphenous AVM model does not cause acute hemodynamic changes. Moderate but progressive alterations and venous dilatation confirmed AVM-like features. The model seems to be suitable for studying further the progression, enlargement, or destabilization of AVM.},
	year = {2023},
	eissn = {2227-9059},
	pages = {2970},
	orcid-numbers = {Aslan, Siran/0009-0007-4352-4102; Bernát, Brigitta Renáta/0000-0001-6090-1001; Németh, Norbert/0000-0002-1162-3778}
}

@article{MTMT:34323619,
	title = {Location-based prediction model for Crohn’s disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies},
	url = {https://m2.mtmt.hu/api/publication/34323619},
	author = {Sipeki, Nóra and Kováts, Patrícia and Deutschmann, Claudia and Schierack, Peter and Roggenbuck, Dirk and Papp, Mária},
	doi = {10.3748/wjg.v29.i42.5728},
	journal-iso = {WORLD J LGASTROENTEROL},
	journal = {WORLD JOURNAL OF GASTROENTEROLOGY},
	volume = {29},
	unique-id = {34323619},
	issn = {1007-9327},
	abstract = {Esophageal cancer (EC) has a high incidence and mortality rate and is emerging as one of the most common health problems globally. Owing to the lack of sensitive detection methods, uncontrollable rapid metastasis, and pervasive treatment resistance, EC is often diagnosed in advanced stages and is susceptible to local recurrence. Exosomes are important components of intercellular communication and the exosome-mediated crosstalk between the cancer and surrounding cells within the tumor microenvironment plays a crucial role in the metastasis, progression, and therapeutic resistance of EC. Considering the critical role of exosomes in tumor pathogenesis, this review focused on elucidating the impact of exosomes on EC metastasis and therapeutic resistance. Here, we summarized the relevant signaling pathways involved in these processes. In addition, we discussed the potential clinical applications of exosomes for the early diagnosis, prognosis, and treatment of EC.},
	year = {2023},
	eissn = {2219-2840},
	pages = {5728-5750},
	orcid-numbers = {Sipeki, Nóra/0000-0002-6806-2991; Papp, Mária/0000-0003-3662-4010}
}

@article{MTMT:34089998,
	title = {Human epididymis protein 4 (HE4) plasma concentration inversely correlates with the improvement of cystic fibrosis lung disease in p.Phe508del-CFTR homozygous cases treated with the CFTR modulator lumacaftor/ivacaftor combination},
	url = {https://m2.mtmt.hu/api/publication/34089998},
	author = {Pócsi, Marianna and Fejes, Zsolt and Bene, Zsolt and Nagy, Attila Csaba and Balogh, István and Amaral, Margarida D. and Macek, Milan and Nagy, Béla},
	doi = {10.1016/j.jcf.2023.04.001},
	journal-iso = {J CYST FIBROS},
	journal = {JOURNAL OF CYSTIC FIBROSIS},
	volume = {22},
	unique-id = {34089998},
	issn = {1569-1993},
	year = {2023},
	eissn = {1873-5010},
	pages = {1085-1092},
	orcid-numbers = {Nagy, Attila Csaba/0000-0002-0554-7350; Balogh, István/0000-0003-3397-2829; Amaral, Margarida D./0000-0002-0828-8630}
}

@article{MTMT:34011238,
	title = {Long-Term Changes in the Biomarkers of Left Atrial Fibrosis after Pulmonary Vein Isolation for Paroxysmal and Persistent Atrial Fibrillation},
	url = {https://m2.mtmt.hu/api/publication/34011238},
	author = {Szuromi, Lilla and Hajas, Orsolya and Nagy-Baló, Edina and Forgács, Ildikó Noémi and László, T. Nagy and Fagyas, Miklós and Tóth, Attila and Nagy, Béla and Kappelmayer, János and Csanádi, Zoltán},
	doi = {10.31083/j.rcm2406171},
	journal-iso = {REV CARDIOVASC MED},
	journal = {REVIEWS IN CARDIOVASCULAR MEDICINE},
	volume = {24},
	unique-id = {34011238},
	issn = {1530-6550},
	year = {2023},
	eissn = {2153-8174}
}