@article{MTMT:34679053, title = {A silica-supported organocatalyst for polycarbonate methanolysis under mild and economic conditions}, url = {https://m2.mtmt.hu/api/publication/34679053}, author = {Fehér, Zsuzsanna and Németh, Réka and Kiss, Johanna and Balterer, Bence and Verebélyi, Klára and Iván, Béla and Kupai, József}, doi = {10.1016/j.cej.2024.149832}, journal-iso = {CHEM ENG J}, journal = {CHEMICAL ENGINEERING JOURNAL}, volume = {485}, unique-id = {34679053}, issn = {1385-8947}, year = {2024}, eissn = {1873-3212}, orcid-numbers = {Németh, Réka/0009-0005-2477-745X; Kiss, Johanna/0000-0003-1969-5300; Iván, Béla/0000-0003-2475-6841; Kupai, József/0000-0002-4212-4517} } @article{MTMT:34191513, title = {Two-Photon Fluorescent Chemosensors Based on the GFP-Chromophore for the Detection of Zn2+ in Biological Samples – From Design to Application}, url = {https://m2.mtmt.hu/api/publication/34191513}, author = {Csomos, Attila and Kovács, Ervin and Madarász, Miklós and Fedor, Flóra Zsófia and Fülöp, Anna and Katona, Gergely and Rózsa J., Balázs and Mucsi, Zoltán}, doi = {10.1016/j.snb.2023.134753}, journal-iso = {SENSOR ACTUAT B CHEM}, journal = {SENSORS AND ACTUATORS B-CHEMICAL}, volume = {398}, unique-id = {34191513}, issn = {0925-4005}, keywords = {FLUORESCENCE; chemosensor; two-photon; Zinc); GFP-chromophore}, year = {2024}, eissn = {0925-4005}, orcid-numbers = {Kovács, Ervin/0000-0002-3939-6925; Madarász, Miklós/0000-0001-7057-303X; Fedor, Flóra Zsófia/0000-0003-4085-1419; Katona, Gergely/0000-0002-4173-0355; Mucsi, Zoltán/0000-0003-3224-8847} } @article{MTMT:34205650, title = {Effective Synthesis, Development and Application of a Highly Fluorescent Cyanine Dye for Antibody Conjugation and Microscopy Imaging}, url = {https://m2.mtmt.hu/api/publication/34205650}, author = {Szepesi Kovács, Dénes and Kontra, Bence and Chiovini, Balázs and Müller, Dalma and Tóth, Estilla Zsófia and Ábrányi-Balogh, Péter and Wittner, Lucia and Várady, György and Turczel, Gábor and Farkas, Ödön and Owen, Michael Christopher and Katona, Gergely and Győrffy, Balázs and Keserű, György Miklós and Mucsi, Zoltán and Rózsa J., Balázs and Kovács, Ervin}, doi = {10.1039/D3OB01471A}, journal-iso = {ORG BIOMOL CHEM}, journal = {ORGANIC & BIOMOLECULAR CHEMISTRY}, volume = {21}, unique-id = {34205650}, issn = {1477-0520}, abstract = {An asymmetric cyanine-type fluorescent dye was designed and synthesized via a versatile, multi-step process, aiming to conjugate with an Her2+ receptor specific antibody by an azide-alkyne click reaction. The aromaticity and the excitation and relaxation energetics of the fluorophore were characterized by computational methods. The synthesized dye exhibited excellent fluorescence properties for confocal microscopy, offering efficient applicability in in vitro imaging due to its merits such as a high molar absorption coefficient (36 816 M-1 cm-1), excellent brightness, optimal wavelength (627 nm), larger Stokes shift (26 nm) and appropriate photostability compared to cyanines. The conjugated cyanine-trastuzumab was constructed via an effective, metal-free, strain-promoted azide-alkyne click reaction leading to a regulated number of dyes being conjugated. This novel cyanine-labelled antibody was successfully applied for in vitro confocal imaging and flow cytometry of Her2+ tumor cells. An azido cyanine dye was synthesized and characterized by computational and experimental techniques and applied in tumor cell imaging.}, keywords = {RECEPTOR; REAGENTS; FUTURE}, year = {2023}, eissn = {1477-0539}, pages = {8829-8836}, orcid-numbers = {Kontra, Bence/0000-0001-8293-3637; Wittner, Lucia/0000-0001-6800-0953; Várady, György/0000-0003-2012-9680; Farkas, Ödön/0000-0002-4217-0150; Katona, Gergely/0000-0002-4173-0355; Győrffy, Balázs/0000-0002-5772-3766; Mucsi, Zoltán/0000-0003-3224-8847; Kovács, Ervin/0000-0002-3939-6925} } @article{MTMT:34016504, title = {Láthatóvá tenni a ráksejteket. Új festék a mikroszkópos tumordiagnosztikábanLáthatóvá tenni a ráksejteket/ Új festék a mikroszkópos tumordiagnosztikában}, url = {https://m2.mtmt.hu/api/publication/34016504}, author = {Kovács, Ervin and Szepesi Kovács, Dénes and Mucsi, Zoltán}, journal-iso = {TERMÉSZET VILÁGA}, journal = {TERMÉSZET VILÁGA}, volume = {154}, unique-id = {34016504}, issn = {0040-3717}, year = {2023}, pages = {259-263}, orcid-numbers = {Kovács, Ervin/0000-0002-3939-6925; Mucsi, Zoltán/0000-0003-3224-8847} } @article{MTMT:34015800, title = {Synthesis and Application of Two-Photon Active Fluorescent Rhodol Dyes for Antibody Conjugation and In Vitro Cell Imaging}, url = {https://m2.mtmt.hu/api/publication/34015800}, author = {Szepesi Kovács, Dénes and Chiovini, Balázs and Müller, Dalma and Tóth, Estilla Zsófia and Fülöp, Anna and Ábrányi-Balogh, Péter and Wittner, Lucia and Várady, György and Farkas, Ödön and Turczel, Gábor and Katona, Gergely and Győrffy, Balázs and Keserű, György Miklós and Mucsi, Zoltán and Rózsa J., Balázs and Kovács, Ervin}, doi = {10.1021/acsomega.3c01796}, journal-iso = {ACS OMEGA}, journal = {ACS OMEGA}, volume = {8}, unique-id = {34015800}, issn = {2470-1343}, year = {2023}, eissn = {2470-1343}, pages = {22836-22843}, orcid-numbers = {Wittner, Lucia/0000-0001-6800-0953; Várady, György/0000-0003-2012-9680; Farkas, Ödön/0000-0002-4217-0150; Katona, Gergely/0000-0002-4173-0355; Győrffy, Balázs/0000-0002-5772-3766; Mucsi, Zoltán/0000-0003-3224-8847; Kovács, Ervin/0000-0002-3939-6925} } @article{MTMT:33700517, title = {Csizmadia Imre Gyulára emlékezve}, url = {https://m2.mtmt.hu/api/publication/33700517}, author = {Kovács, Ervin and Mucsi, Zoltán}, journal-iso = {MAGY KEM LAP}, journal = {MAGYAR KÉMIKUSOK LAPJA}, volume = {78}, unique-id = {33700517}, issn = {0025-0163}, year = {2023}, eissn = {1588-1199}, pages = {30-31}, orcid-numbers = {Kovács, Ervin/0000-0002-3939-6925; Mucsi, Zoltán/0000-0003-3224-8847} } @article{MTMT:33700427, title = {A szerves kémia digitalizációjának úttörője – Megemlékezés Csizmadia Imre Gyula professzorról}, url = {https://m2.mtmt.hu/api/publication/33700427}, author = {Kovács, Ervin and Mucsi, Zoltán}, journal-iso = {TERMÉSZET VILÁGA}, journal = {TERMÉSZET VILÁGA}, volume = {154}, unique-id = {33700427}, issn = {0040-3717}, year = {2023}, pages = {102-107}, orcid-numbers = {Kovács, Ervin/0000-0002-3939-6925; Mucsi, Zoltán/0000-0003-3224-8847} } @article{MTMT:33687683, title = {Highly Efficient Cationic Polymerization of β-Pinene, a Bio-Based, Renewable Olefin, with TiCl4 Catalyst from Cryogenic to Energy-Saving Room Temperature Conditions}, url = {https://m2.mtmt.hu/api/publication/33687683}, author = {Verebélyi, Klára and Szabó, Ákos and Réti, Zsombor and Szarka, Györgyi Éva and Villányi, Ákos and Iván, Béla}, doi = {10.3390/ijms24065170}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {24}, unique-id = {33687683}, issn = {1661-6596}, abstract = {Polymers based on renewable monomers are projected to have a significant role in the sustainable economy, even in the near future. Undoubtedly, the cationically polymerizable β-pinene, available in considerable quantities, is one of the most promising bio-based monomers for such purposes. In the course of our systematic investigations related to the catalytic activity of TiCl4 on the cationic polymerization of this natural olefin, it was found that the 2-chloro-2,4,4-trimethylpentane (TMPCl)/TiCl4/N,N,N′,N′-tetramethylethylenediamine (TMEDA) initiating system induced efficient polymerization in dichloromethane (DCM)/hexane (Hx) mixture at both −78 °C and room temperature. At −78 °C, 100% monomer conversion was observed within 40 min, resulting in poly(β-pinene) with relatively high Mn (5500 g/mol). The molecular weight distributions (MWD) were uniformly shifted towards higher molecular weights (MW) in these polymerizations as long as monomer was present in the reaction mixture. However, chain–chain coupling took place after reaching 100% conversion, i.e., under monomer-starved conditions, resulting in considerable molecular weight increase and MWD broadening at −78 °C. At room temperature, the polymerization rate was lower, but chain coupling did not occur. The addition of a second feed of monomer in the polymerization system led to increasing conversion and polymers with higher MWs at both temperatures. 1H NMR spectra of the formed polymers indicated high in-chain double-bond contents. To overcome the polarity decrease by raising the temperature, polymerizations were also carried out in pure DCM at room temperature and at −20 °C. In both cases, rapid polymerization occurred with nearly quantitative yields, leading to poly(β-pinene)s with Mns in the range of 2000 g/mol. Strikingly, polymerization by TiCl4 alone, i.e., without any additive, also occurred with near complete conversion at room temperature within a few minutes, attributed to initiation by adventitious protic impurities. These results convincingly prove that highly efficient carbocationic polymerization of the renewable β-pinene can be accomplished with TiCl4 as catalyst under both cryogenic conditions, applied widely for carbocationic polymerizations, and the environmentally benign, energy-saving room temperature, i.e., without any additive and cooling or heating. These findings enable TiCl4-catalyzed eco-friendly manufacturing of poly(β-pinene)s, which can be utilized in various applications, and in addition, subsequent derivatizations could result in a range of high-added-value products.}, year = {2023}, eissn = {1422-0067}, orcid-numbers = {Iván, Béla/0000-0003-2475-6841} } @article{MTMT:33674915, title = {Investigation of poly(3,6-dioxa-1,8-octane-dithiol)-based organosulfur polymer as the positive electrode material in rechargeable Li-S battery}, url = {https://m2.mtmt.hu/api/publication/33674915}, author = {Ovc-Okene , Derek and Angamuthu, Gnanavel and Szabó, Ákos and Szarka, Györgyi Éva and Iván, Béla and Kun, Róbert}, doi = {10.1016/j.jelechem.2022.117113}, journal-iso = {J ELECTROANAL CHEM}, journal = {JOURNAL OF ELECTROANALYTICAL CHEMISTRY}, volume = {929}, unique-id = {33674915}, issn = {1572-6657}, year = {2023}, eissn = {1873-2569}, orcid-numbers = {Iván, Béla/0000-0003-2475-6841} } @article{MTMT:33532503, title = {Ring-Opening Metathesis Polymerization and Related Olefin Metathesis Reactions in Benzotrifluoride as an Environmentally Advantageous Medium}, url = {https://m2.mtmt.hu/api/publication/33532503}, author = {Kovács, Ervin and Balterer, Bence and Nguyen, Duc and Szarka, Györgyi Éva and Owen, Michael Christopher and Domján, Attila and Iván, Béla}, doi = {10.3390/ijms24010671}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {24}, unique-id = {33532503}, issn = {1661-6596}, abstract = {A tremendous number of solvents, either as liquids or vapors, contaminate the environment on a daily basis worldwide. Olefin metathesis, which has been widely used as high-yielding protocols for ring-opening metathesis polymerization (ROMP), ring-closing metathesis (RCM), and isomerization reactions, is typically performed in toxic and volatile solvents such as dichloromethane. In this study, the results of our systematic experiments with the Grubbs G1, G2, and Hoveyda-Grubbs HG2 catalysts proved that benzotrifluoride (BTF) can replace dichloromethane (DCM) in these reactions, providing high yields and similar or even higher reaction rates in certain cases. The ROMP of norbornene resulted not only in high yields but also in polynorbornenes with a high molecular weight at low catalyst loadings. Ring-closing metathesis (RCM) experiments proved that, with the exception of the G1 catalyst, RCM occurs with similar high efficiencies in BTF as in DCM. It was found that isomerization of (Z)-but-2-ene-1,4-diyl diacetate with the G2 and HG2 catalysts proceeds at significantly higher initial rates in BTF than in DCM, leading to rapid isomerization with high yields in a short time. Overall, BTF is a suitable solvent for olefin metathesis, such as polymer syntheses by ROMP and the ring-closing and isomerization reactions.}, keywords = {ISOMERIZATION; NORBORNENE; OLEFIN METATHESIS; Green solvent; ring-opening metathesis polymerization (ROMP); Benzotrifluoride; Homogenous catalysis; ring-closing metathesis (RCM)}, year = {2023}, eissn = {1422-0067}, orcid-numbers = {Kovács, Ervin/0000-0002-3939-6925} }