TY - CONF AU - Marosvölgyi, Tamás AU - Mintál, Kitti AU - Borbásné Farkas, Kornélia AU - Makszin, Lilla AU - Szabó, Éva AU - Attila, Toth AU - Béla, Kocsis AU - Zoltan, Karadi AU - Bufa, Anita TI - Antibiotic-induced effects on the fatty acid composition of faeces in a rat model T2 - 2023 15th International ISSFAL Congress PY - 2023 SP - 269 UR - https://m2.mtmt.hu/api/publication/34797768 ID - 34797768 LA - English DB - MTMT ER - TY - BOOK AU - Pótó, László TI - Biometria. Kísérleti tankönyv az 1. félévi Biometria gyakorlathoz TS - Kísérleti tankönyv az 1. félévi Biometria gyakorlathoz PB - Pécsi Tudományegyetem Általános Orvostudományi Kar CY - Pécs PY - 2020 SP - 235 UR - https://m2.mtmt.hu/api/publication/32039615 ID - 32039615 LA - Hungarian DB - MTMT ER - TY - BOOK AU - Pótó, László TI - Biometrics. Workbook for the first course in statistics for medical students TS - Workbook for the first course in statistics for medical students PB - Pécsi Tudományegyetem Általános Orvostudományi Kar CY - Pécs PY - 2020 SP - 220 UR - https://m2.mtmt.hu/api/publication/32039604 ID - 32039604 LA - English DB - MTMT ER - TY - JOUR AU - Böröcz, Katalin AU - Hayden, Zsófia AU - Meszaros, V AU - Csizmadia, Zsuzsanna AU - Borbásné Farkas, Kornélia AU - Kellermayer, Zoltán AU - Balogh, Péter AU - Nagy, Ferenc AU - Berki, Tímea TI - Az autoimmun encephalitisek laboratóriumi vizsgálati lehetőségei JF - ORVOSI HETILAP J2 - ORV HETIL VL - 159 PY - 2018 IS - 3 SP - 107 EP - 112 PG - 6 SN - 0030-6002 DO - 10.1556/650.2018.30951 UR - https://m2.mtmt.hu/api/publication/3317990 ID - 3317990 N1 - TT: [Autoimmune encephalitis: possibilities in the laboratory investigation] AB - INTRODUCTION: The role of autoimmune responses against central nervous system (CNS) antigens in encephalitis presenting with non-classified neurologic or psychiatric symptoms has been appreciated in the past decade. Paraneoplastic limbic encephalitis has a poor prognosis and is most commonly associated with lung, ovarium, and testicular neoplasms, leading to immune reactions against intracellular antigens (anti-Hu/ANNA1, anti-Ri/ANNA2, anti-CV2/CRMP5 and anti-Ma2/Ta). In contrast, the recently described autoimmune encephalitis subtypes present with a broad spectrum of symptoms, respond to autoimmune therapies well and usually associate with autoantibodies against neuronal cell surface receptors (NMDAR, GABABR, AMPAR) or synaptic proteins (LGI1, CASPR2). AIM: Our aim is to bring to awareness the increasing number of autoimmune encephalitis patients requiring neurologic, psychiatric and intensive care and to emphasize the significance of detecting various autoantibodies in diagnosing patients. METHOD: In the past 6 years, our laboratory received 836 autoimmune encephalitis diagnostic test requests from a total of 717 patients. Serum and cerebrospinal fluid (CSF) samples were analysed with indirect immunofluorescence using a BIOCHIP consisting of cell lines transfected with 6 different receptor proteins. RESULTS: IgG autoantibodies against receptor proteins were present in 7.5% of patients. The frequency of positive samples was the following: NMDAR > LGI1 > GABABR > CASPR2. CONCLUSION: Detecting autoantibodies facilitates the diagnosis of autoimmune encephalitis in an early stage. Patients diagnosed early can be effectively treated with plasmapheresis and immunosuppressive drugs. The efficiency of therapies can be monitored by autoantibody detection. Therefore, the diagnostic immune laboratory plays an important role in proper diagnosis and in the prevention of rapidly progressing symptoms. Orv Hetil. 2018; 159(3): 107-112. LA - Hungarian DB - MTMT ER -