TY - JOUR AU - Laczi, Miklós AU - Sarkadi, Fanni AU - Herényi, Márton AU - Nagy, Gergely AU - Hegyi, Gergely AU - Jablonszky, Mónika AU - Könczey, Réka AU - Krenhardt, Katalin AU - Markó, Gábor AU - Rosivall, Balázs AU - Szász, Eszter AU - Szöllősi, Eszter AU - Tóth, László AU - Zsebők, Sándor AU - Török, János TI - Responses in the breeding parameters of the collared flycatcher to the changing climate JF - SCIENCE OF THE TOTAL ENVIRONMENT J2 - SCI TOTAL ENVIRON VL - 926 PY - 2024 SN - 0048-9697 DO - 10.1016/j.scitotenv.2024.171945 UR - https://m2.mtmt.hu/api/publication/34787582 ID - 34787582 N1 - HUN-REN–ELTE–MTM Integrative Ecology Research Group, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest, H-1117, Hungary Behavioural Ecology Group, Department of Systematic Zoology and Ecology, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest, H-1117, Hungary The Barn Owl Foundation, Temesvári út 8., Orosztony, H-8744, Hungary Doctoral School of Biology, Institute of Biology, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest, H-1117, Hungary Department of Zoology and Ecology, Institute for Wildlife Management and Nature Conservation, Hungarian University of Agriculture and Life Sciences, Páter Károly utca 1, Gödöllő, H-2103, Hungary Evolutionary Ecology Research Group, Institute of Ecology and Botany, Centre for Ecological Research, Alkotmány út 4., Vácrátót, H-2163, Hungary Hungarian Institute for Educational Research and Development, Eszterházy Károly University, Rákóczi út 70, Budapest, H-1074, Hungary Department of Plant Pathology, Institute of Plant Protection, Hungarian University of Agriculture and Life Sciences, Ménesi út 44., Budapest, H-1118, Hungary Institute for Rural Development and Landscape Management, Faculty of Agricultural and Rural Development, Eszterházy Károly University, Mátrai út 36., Gyöngyös, H-3200, Hungary Export Date: 15 April 2024 CODEN: STEVA Correspondence Address: Laczi, M.; HUN-REN–ELTE–MTM Integrative Ecology Research Group, Pázmány Péter sétány 1/C, Hungary; email: miklos.laczi@ttk.elte.hu LA - English DB - MTMT ER - TY - JOUR AU - Horváth, Lilla AU - Biri-Kovács, Beáta AU - Baranyai, Zsuzsa AU - Stipsicz, Bence András AU - Méhes, Előd AU - Jezsó, Bálint AU - Krátký, Martin AU - Vinšová, Jarmila AU - Bősze, Szilvia TI - New Salicylanilide Derivatives and Their Peptide Conjugates as Anticancer Compounds: Synthesis, Characterization, and In Vitro Effect on Glioblastoma JF - ACS OMEGA J2 - ACS OMEGA VL - 9 PY - 2024 IS - 15 SP - 16927 EP - 16948 PG - 22 SN - 2470-1343 DO - 10.1021/acsomega.3c05727 UR - https://m2.mtmt.hu/api/publication/34777528 ID - 34777528 LA - English DB - MTMT ER - TY - JOUR AU - Rani, Varsha AU - Horváth, Zsófia AU - Nejstgaard, Jens C. AU - Fierpasz, Ádám AU - Pálffy, Károly AU - Vad, Csaba Ferenc TI - Food density drives diet shift of the invasive mysid shrimp, Limnomysis benedeni JF - ECOLOGY AND EVOLUTION J2 - ECOL EVOL VL - 14 PY - 2024 IS - 4 SN - 2045-7758 DO - 10.1002/ece3.11202 UR - https://m2.mtmt.hu/api/publication/34774857 ID - 34774857 N1 - Submitted to Ecology and Evolution October 04, 2023; Review(s) Completed, Editorial Evaluation Pending 22 Nov 2023. https://doi.org/10.22541/au.169642823.39376932/v1 AB - Understanding the diet preferences and food selection of invasive species is crucial to better predict their impact on community structure and ecosystem functioning. Limnomysis benedeni , a Ponto‐Caspian invasive mysid shrimp, is one of the most successful invaders in numerous European river and lake ecosystems. While existing studies suggest potentially strong trophic impact due to high predation pressure on native plankton communities, little is known of its food selectivity between phyto‐ and zooplankton, under different food concentrations. Here, we therefore investigated the feeding selectivity of L . benedeni on two commonly occurring prey organisms in freshwaters, the small rotifer zooplankton Brachionus calyciflorus together with the microphytoplankton Cryptomonas sp. present in increasing densities. Our results demonstrated a clear shift in food selection, with L. benedeni switching from B. calyciflorus to Cryptomonas sp. already when the two prey species were provided in equal biomasses. Different functional responses were observed for the two food types, indicating somewhat different foraging mechanisms for each food type. These findings provide experimental evidence on the feeding flexibility of invasive mysid shrimps and potential implications for trophic interactions in invaded ecosystems. LA - English DB - MTMT ER - TY - JOUR AU - Tóth, Attila István AU - Keserű, Dóra AU - Pethő, Máté AU - Détári, László AU - Bencsik, Norbert AU - Dobolyi, Árpád AU - Hajnik, Tünde TI - Sleep and local field potential effect of the D2 receptor agonist bromocriptine during the estrus cycle and postpartum period in female rats JF - PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR J2 - PHARMACOL BIOCHEM BE VL - 239 PY - 2024 SN - 0091-3057 DO - 10.1016/j.pbb.2024.173754 UR - https://m2.mtmt.hu/api/publication/34755849 ID - 34755849 N1 - In vivo Electrophysiology Research Group, Department of Physiology and Neurobiology, Eötvös Loránd University, Hungary Cellular Neurobiology Research Group, Department of Physiology and Neurobiology, Eötvös Loránd University, Hungary Laboratory of Molecular and Systems Neurobiology, Department of Physiology and Neurobiology, Eötvös Loránd University, Hungary Export Date: 23 April 2024 CODEN: PBBHA Correspondence Address: Tóth, A.; Department of Physiology and Neurobiology, Pázmány Péter sétány 1/C, Hungary; email: attila.toth@ttk.elte.hu LA - English DB - MTMT ER - TY - JOUR AU - Paczkó, Mátyás AU - Vörös, Dániel AU - Szabó, Péter AU - Jékely, Gáspár AU - Szathmáry, Eörs AU - Szilágyi, András TI - A neural network-based model framework for cell-fate decisions and development JF - COMMUNICATIONS BIOLOGY J2 - COMMUN BIOL VL - 7 PY - 2024 IS - 1 SN - 2399-3642 DO - 10.1038/s42003-024-05985-1 UR - https://m2.mtmt.hu/api/publication/34743931 ID - 34743931 N1 - Institute of Evolution, HUN-REN Centre for Ecological Research, Konkoly-Thege M. út 29-33, Budapest, 1121, Hungary Doctoral School of Biology, Institute of Biology, ELTE Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest, 1117, Hungary Living Systems Institute, University of Exeter, Stocker Road 4QD, Exeter, EX4, United Kingdom Center for the Conceptual Foundations of Science, Parmenides Foundation, Hindenburgstr. 15, Pöcking, 82343, Germany Department of Plant Systematics, Ecology and Theoretical Biology, Eötvös Loránd University, Pázmány Péter sétány 1/C, Budapest, 1117, Hungary Export Date: 17 April 2024 Correspondence Address: Szathmáry, E.; Institute of Evolution, Konkoly-Thege M. út 29-33, Hungary; email: szathmary.eors@ecolres.hu AB - Gene regulatory networks (GRNs) fulfill the essential function of maintaining the stability of cellular differentiation states by sustaining lineage-specific gene expression, while driving the progression of development. However, accounting for the relative stability of intermediate differentiation stages and their divergent trajectories remains a major challenge for models of developmental biology. Here, we develop an empirical data-based associative GRN model (AGRN) in which regulatory networks store multilineage stage-specific gene expression profiles as associative memory patterns. These networks are capable of responding to multiple instructive signals and, depending on signal timing and identity, can dynamically drive the differentiation of multipotent cells toward different cell state attractors. The AGRN dynamics can thus generate diverse lineage-committed cell populations in a robust yet flexible manner, providing an attractor-based explanation for signal-driven cell fate decisions during differentiation and offering a readily generalizable modelling tool that can be applied to a wide variety of cell specification systems. LA - English DB - MTMT ER - TY - JOUR AU - Liszkai-Peres, Krisztina AU - Budai, Zsófia AU - Adrienn, Kocsis AU - Jurányi, Zsolt AU - Pogány, Ákos AU - Kampis, György AU - Miklósi, Ádám AU - Konok, Veronika TI - Association between mobile touchscreen devices (MTSDs) and the quality of parent-child interaction in preschoolers JF - Frontiers in Child and Adolescent Psychiatry VL - 3 PY - 2024 SN - 2813-4540 DO - 10.3389/frcha.2024.1330243 UR - https://m2.mtmt.hu/api/publication/34726766 ID - 34726766 LA - English DB - MTMT ER - TY - JOUR AU - Boros, Marianna AU - Magyari, Lilla AU - Morvai, Boglárka AU - Raúl, Hernandez-Perez AU - Dror, Shany AU - Andics, Attila TI - Neural evidence for referential understanding of object words in dogs JF - CURRENT BIOLOGY J2 - CURR BIOL VL - 34 PY - 2024 IS - 8 SP - 1750 EP - 1754 PG - 5 SN - 0960-9822 DO - 10.1016/j.cub.2024.02.029 UR - https://m2.mtmt.hu/api/publication/34726473 ID - 34726473 N1 - Export Date: 24 April 2024 CODEN: CUBLE Correspondence Address: Boros, M.; Neuroethology of Communication Lab, Pázmány Péter sétány 1/C, Hungary; email: marianna.cs.boros@gmail.com Correspondence Address: Magyari, L.; Neuroethology of Communication Lab, Pázmány Péter sétány 1/C, Hungary; email: lilla.magyari@uis.no AB - Using words to refer to objects in the environment is a core feature of the human language faculty. Referential understanding assumes the formation of mental representations of these words1,2. Such understanding of object words has not yet been demonstrated as a general capacity in any non-human species,3 despite multiple behaviour-based case reports.4–10 In human event-related potential (ERP) studies, object word knowledge is typically tested using the semantic violation paradigm, where words are presented either with their referent (match) or another object (mismatch).11,12 Such mismatch elicits an N400 effect, a well-established neural correlate of semantic processing.12,13 Reports of preverbal infant N400 evoked by semantic violations14 asserts the use of this paradigm to probe mental representations of object words in nonverbal populations. Here, measuring dogs’ (Canis familiaris) ERPs to objects primed with matching or mismatching object words, we found a mismatch effect at a frontal electrode, with a latency (206-606 ms) comparable to the human N400. A greater difference for words that dogs knew better, according to owner reports, further supported a semantic interpretation of this effect. Semantic expectations emerged irrespective of vocabulary size, demonstrating the prevalence of referential understanding in dogs. These results provide the first neural evidence for object word knowledge in a non-human animal. LA - English DB - MTMT ER - TY - GEN AU - Turek, Cezary AU - Olbei, Marton AU - Stirling, Tamás AU - Fekete, Gergely AU - Tasnádi, Ervin Áron AU - Gul, Leila AU - Bohár, Balázs AU - Papp, Balázs AU - Jurkowski, Wiktor AU - Ari, Eszter TI - mulea - an R package for enrichment analysis using multiple ontologies and empirical FDR correction PY - 2024 UR - https://m2.mtmt.hu/api/publication/34718081 ID - 34718081 AB - Traditional gene set enrichment analyses are typically limited to a few ontologies and do not account for the interdependence of gene sets or terms, resulting in overcorrected p-values. To address these challenges, we introduce mulea, an R package offering comprehensive overrepresentation and functional enrichment analysis. mulea employs an innovative empirical false discovery rate (eFDR) correction method, specifically designed for interconnected biological data, to accurately identify significant terms within diverse ontologies. mulea expands beyond traditional tools by incorporating a wide range of ontologies, encompassing Gene Ontology, pathways, regulatory elements, genomic locations, and protein domains. This flexibility enables researchers to tailor enrichment analysis to their specific questions, such as identifying enriched transcriptional regulators in gene expression data or overrepresented protein domains in protein sets. To facilitate seamless analysis, mulea provides gene sets (in standardised GMT format) for 27 model organisms, covering 16 databases and various identifiers resulting in almost 900 files. Additionally, the muleaData ExperimentData Bioconductor package simplifies access to these pre-defined ontologies. Finally, mulea's architecture allows for easy integration of user-defined ontologies, expanding its applicability across diverse research areas. Availability and Implementation: Software for the tools demonstrated in this article is available as an R package on GitHub: https://github.com/ELTEbioinformatics/mulea. LA - English DB - MTMT ER - TY - JOUR AU - Fodor, Erika Gabriella AU - Javan, Okendo AU - Nóra, Szabó AU - Kata, Szabó AU - Czimer, Dávid Gyula AU - Anita, Tarján-Rácz AU - Szeverényi, Ildikó AU - Bi, Wei Low AU - Jia, Huan Liew AU - Sergey, Koren AU - Arang, Rhie AU - Orbán, László AU - Miklósi, Ádám AU - Varga, Máté AU - Shawn, M. Burgess TI - The reference genome of paradise fish (Macropodus opercularis) JF - SCIENTIFIC DATA J2 - SCI DATA PY - 2024 SN - 2052-4463 UR - https://m2.mtmt.hu/api/publication/34714841 ID - 34714841 LA - English DB - MTMT ER - TY - JOUR AU - Ecsédi, Péter AU - Pálinkás, János AU - Kovács, Zoltán AU - Harami, Gábor AU - Juhasz, Tunde AU - Jezsó, Bálint AU - Erfalvy, David AU - Mahmudova, Lamiya AU - Házy, Eszter AU - Beke-Somfai, Tamas AU - Kovács, Mihály TI - Functional contribution of condensate formation by single-stranded DNA binding protein (SSB) to bacterial genome maintenance JF - BIOPHYSICAL JOURNAL J2 - BIOPHYS J VL - 123 PY - 2024 IS - 3 SP - 79a EP - 80a SN - 0006-3495 DO - 10.1016/j.bpj.2023.11.547 UR - https://m2.mtmt.hu/api/publication/34685848 ID - 34685848 LA - English DB - MTMT ER -