TY - JOUR AU - Cserni, Gábor AU - Bori, Rita AU - Ambrózay, Éva AU - Serfőző, Orsolya TI - Histological Patterns and Mammographic Presentation of Invasive Lobular Carcinoma Show No Obvious Associations JF - CANCERS J2 - CANCERS VL - 16 PY - 2024 IS - 9 PG - 17 SN - 2072-6694 DO - 10.3390/cancers16091640 UR - https://m2.mtmt.hu/api/publication/34821848 ID - 34821848 AB - Invasive lobular carcinoma of the breast has different mammographic appearances, including spiculated or lobulated masses, architectural distortion, increased breast density, and the possibility of also being occult. Histologically, the morphology is also variable, as several patterns have been described beside the classical one, including the solid, the alveolar, the trabecular, the one with tubular elements, and others. Of 146 ILC cases, 141 were reviewed for mammographic appearance and 136 for histological patterns by two radiologist and two pathologists, respectively; 132 common cases were analyzed for possible associations between mammographic presentation and the histological patterns. Interobserver agreement on the presence or absence of a given mammographic morphology ranged from 45% (increased density) to 95% (occult lesion); the most common radiomorphology was that of a spiculated mass. Interobserver agreement on the presence or absence of a given histological pattern ranged between 79% (solid) and 99% (classical) but was worse when semi-quantification was also included. The mammography–pathology correlation was less than optimal. Multifocality was more commonly detected by histology. The identification of a mammographic mass lesion often coincided with a mass-like lesion on the histological slides and vice versa, but nearly half of the mammographically occult lesions were felt to have masses on histological slides assessed grossly. Histological patterns showed no obvious associations with one or the other mammographic appearance. LA - English DB - MTMT ER - TY - JOUR AU - Ferenczi, Ádám AU - Kuthi, Levente AU - Sejben, István AU - Sejben, Anita TI - Colonic tubular adenoma with clear cell change – case report with whole exome sequencing and updated review of the literature JF - PATHOBIOLOGY J2 - PATHOBIOLOGY VL - & PY - 2024 SP - & SN - 1015-2008 DO - 10.1159/000538705 UR - https://m2.mtmt.hu/api/publication/34774854 ID - 34774854 AB - Introduction: Colorectal tubular adenomas displaying clear cell change are rare entities, with unknown clinical relevance, prognosis, immunohistochemical, and molecular features. Case presentation: Hereby we report a case of a 43-year-old female patient with a rectosigmoid polyp. Histologically, conventional dysplasia was visible with scattered areas displaying clear cell change. Whole exome sequencing (WES) was carried out and revealed high tumour mutation burden, and 7 pathogenic mutations, including TP53, APC, FGFR4, EHBP1, IL4R, TYR, and ACTN3.Conclusion: Clear cell change may only be present in less than 0,1% of adenomas. Aetiology is not well understood, additionally, few authors suggest autolysis or fixation problems. Our WES resulted in newly found pathogenic mutations, and high mutation burden, proving the lesion’s neoplastic origin. Hitherto, neither special stainings, nor immunohistochemical markers proved to be useful in the diagnostic process. From a differential diagnostic perspective, enteroblastic differentiation, primary and secondary clear cell adenocarcinoma has to be excluded. LA - English DB - MTMT ER - TY - JOUR AU - Szűcs, Diána AU - Monostori, Tamás AU - Vanda, Miklós AU - Páhi, Zoltán Gábor AU - Szilard, Poliska AU - Kemény, Lajos AU - Veréb, Zoltán TI - Licensing effects of inflammatory factors and TLR ligands on the regenerative capacity of adipose-derived mesenchymal stem cells JF - FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY J2 - FRONT CELL DEV BIOL VL - 12 PY - 2024 PG - 15 SN - 2296-634X DO - 10.3389/fcell.2024.1367242 UR - https://m2.mtmt.hu/api/publication/34757445 ID - 34757445 N1 - Regenerative Medicine and Cellular Pharmacology Laboratory, Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Doctoral School of Clinical Medicine, University of Szeged, Szeged, Hungary Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Szeged, Hungary Biobank, University of Szeged, Szeged, Hungary Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), University of Szeged, Szeged, Hungary Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary Genomic Medicine and Bioinformatics Core Facility, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary Hungarian Centre of Excellence for Molecular Medicine-USz Skin Research Group, University of Szeged, Szeged, Hungary Export Date: 26 April 2024 Correspondence Address: Veréb, Z.; Regenerative Medicine and Cellular Pharmacology Laboratory, Hungary; email: vereb.zoltan@med.u-szeged.hu LA - English DB - MTMT ER - TY - JOUR AU - Bacsur, Péter AU - Wetwittayakhlang, Panu AU - Resál, Tamás AU - Földi, Emese AU - Vasas, Béla AU - Farkas, Bernadett AU - Rutka, Mariann AU - Bessissow, Talat AU - Afif, Waqqas AU - Bálint, Anita AU - Fábián, Anna AU - Bor, Renáta AU - Szepes, Zoltán AU - Farkas, Klaudia AU - Lakatos, Péter László AU - Molnár, Tamás TI - Accuracy of the Pancolonic Modified Mayo Score in predicting the long-term outcomes of ulcerative colitis: a promising scoring system JF - THERAPEUTIC ADVANCES IN GASTROENTEROLOGY J2 - THER ADV GASTROENTER VL - 17 PY - 2024 PG - 11 SN - 1756-283X DO - 10.1177/17562848241239606 UR - https://m2.mtmt.hu/api/publication/34752035 ID - 34752035 N1 - First published online March 21, 2024 LA - English DB - MTMT ER - TY - JOUR AU - Ébert, Attila AU - Gál, Eleonóra AU - Tóth, Emese AU - Szögi, Titanilla AU - Hegyi, Péter AU - Venglovecz, Viktória TI - Role of CFTR in diabetes‐induced pancreatic ductal fluid and HCO 3 − secretion JF - JOURNAL OF PHYSIOLOGY-LONDON J2 - J PHYSIOL-LONDON VL - 602 PY - 2024 IS - 6 SP - 1065 EP - 1083 PG - 19 SN - 0022-3751 DO - 10.1113/JP285702 UR - https://m2.mtmt.hu/api/publication/34677129 ID - 34677129 N1 - Funding Agency and Grant Number: CF-Trust CFRD-SRC [SRC 007]; National Research, Development and Innovation Office [SNN134497]; New National Excellence Program Of The Ministry Of Human Capacities [UNKP-18-4] Funding text: We are grateful for support for this study provided by the CF-Trust CFRD-SRC Grant (No.: SRC 007) and the National Research, Development and Innovation Office (SNN134497) and New National Excellence Program Of The Ministry Of Human Capacities (UNKP-18-4 to VV). LA - English DB - MTMT ER - TY - JOUR AU - Magyar, Dániel AU - Fábián, Anna AU - Vasas, Béla AU - Nacsev, Krisztián AU - Dubravcsik, Zsolt AU - Bősze, Zsófia AU - Tóth, Tibor AU - Bacsur, Péter AU - Bálint, Anita AU - Farkas, Klaudia AU - Molnár, Tamás AU - Resál, Tamás AU - Bor, Renáta AU - Szepes, Zoltán TI - Szűrő kolonoszkópos vizsgálatok hatékonyságának és biztonságosságának értékelése a Szegedi Tudományegyetemen és a Bács-Kiskun Vármegyei Oktatókórházban 2019 és 2022 között [Analysis of efficacy and safety of colonoscopic screening program at the University of Szeged and the Bács-Kiskun County Teaching Hospital between 2019 and 2022] JF - ORVOSI HETILAP J2 - ORV HETIL VL - 165 PY - 2024 IS - 6 SP - 221 EP - 231 PG - 11 SN - 0030-6002 DO - 10.1556/650.2024.32979 UR - https://m2.mtmt.hu/api/publication/34635367 ID - 34635367 N1 - Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szeged, Hungary Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szent-Györgyi Albert Klinikai Központ, Belgyógyászati Klinika, Szeged, Hungary Szegedi Tudományegyetem, Általános Orvostudományi Kar, Szent-Györgyi Albert Klinikai Központ, Patológiai Intézet, Szeged, Hungary Bács-Kiskun Vármegyei Oktatókórház, Kecskemét, Hungary Kálvária sgt. 57., 6725, Szeged, Hungary Export Date: 17 March 2024 CODEN: ORHEA Chemicals/CAS: midazolam, 59467-70-8, 59467-96-8 LA - Hungarian DB - MTMT ER - TY - GEN AU - Indira, Pla AU - Botond, L. Szabolcs AU - Petra, Nikolett Péter AU - Zsuzsanna, Ujfaludi AU - Yonghyo, Kim AU - Peter, Horvatovich AU - Aniel, Sanchez AU - Krzysztof, Pawlowski Elisabet Wieslander AU - Jéssica, Guedes AU - Dorottya, MP Pál AU - Anna, A. Ascsillán AU - Lazaro, Hiram Betancourt AU - István, Balázs Németh AU - Jeovanis, Gil AU - Natália, Pinto de Almeida AU - Beáta, Szeitz AU - Leticia, Szadai AU - Viktória, Doma AU - Nicole, Woldmar AU - Áron, Bartha AU - Zoltan, Pahi AU - Pankotai, Tibor AU - Balázs, Győrffy AU - A., Marcell Szasz AU - Gilberto, Domont AU - Fábio, Nogueira AU - Ho, Jeong Kwon AU - Roger, Appelqvist AU - Sarolta, Kárpáti AU - David, Fenyö AU - Johan, Malm AU - György, Marko-Varga AU - Lajos, V. Kemény TI - Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction PY - 2024 UR - https://m2.mtmt.hu/api/publication/34588333 ID - 34588333 N1 - bioRxiv LA - English DB - MTMT ER - TY - JOUR AU - Vereckei, András AU - Besenyi, Zsuzsanna AU - Nagy, Viktória AU - Radics, Bence AU - Vágó, Hajnalka AU - Jenei, Zsigmond AU - Katona, Gábor AU - Sepp, Róbert TI - Cardiac Sarcoidosis: A Comprehensive Clinical Review JF - REVIEWS IN CARDIOVASCULAR MEDICINE J2 - REV CARDIOVASC MED VL - 25 PY - 2024 IS - 2 PG - 18 SN - 1530-6550 DO - 10.31083/j.rcm2502037 UR - https://m2.mtmt.hu/api/publication/34557470 ID - 34557470 N1 - Department of Medicine and Hematology, Semmelweis University, Budapest, 1088, Hungary Department of Nuclear Medicine, University of Szeged, Szeged, 6720, Hungary Division of Non-Invasive Cardiology, Department of Medicine, University of Szeged, Szeged, 6720, Hungary Department of Pathology, University of Szeged, Szeged, 6720, Hungary Heart and Vascular Center, Semmelweis University, Budapest, 1122, Hungary Export Date: 19 March 2024 CODEN: RCMEC Correspondence Address: Vereckei, A.; Department of Medicine and Hematology, Hungary; email: vereckei.andras@med.semmelweis-univ.hu LA - English DB - MTMT ER - TY - JOUR AU - Pancsa, Tamás AU - Dénes, Borbála AU - Somorácz, Áron AU - Kelemen, Dóra AU - Salamon, Ferenc AU - Sánta, Fanni Viktória AU - Kuthi, Levente TI - Primary follicular dendritic cell sarcoma of the kidney – a case report of a rare tumor with emphasis on diagnostic pitfalls JF - DIAGNOSTIC PATHOLOGY J2 - DIAGN PATHOL VL - 19 PY - 2024 IS - 1 PG - 6 SN - 1746-1596 DO - 10.1186/s13000-024-01444-x UR - https://m2.mtmt.hu/api/publication/34547544 ID - 34547544 N1 - Szövegében 3 oldalnál rövidebb esetismertetés, ezért besorolása rövid közlemény az MTA V. Osztályának ajánlása alapján. (SzF, SZTE admin5, 2024-01-31) LA - English DB - MTMT ER - TY - JOUR AU - Jójárt, Boldizsár AU - Csákány-Papp, Noémi AU - Laub, H AU - Vasas, Béla AU - Barta, B AU - Szabó, Viktória AU - Bagyánszki, Mária AU - Mándity, I AU - Heltovics, G AU - Pallagi, Petra AU - Maléth, József TI - P072 LDN-071, a novel first-in-class amino acid-based PAI-1 inhibitor, significantly reduces the severity of experimental colitis in mice JF - JOURNAL OF CROHNS & COLITIS J2 - J CROHNS COLITIS VL - 18 PY - 2024 IS - Supplement_1 SP - i342 EP - i342 PG - 1 SN - 1873-9946 DO - 10.1093/ecco-jcc/jjad212.0202 UR - https://m2.mtmt.hu/api/publication/34538600 ID - 34538600 LA - English DB - MTMT ER -