@article{MTMT:34794084, title = {Assessment of a novel electrochemically deposited smart bioactive trabecular coating (SBTC®): a randomized controlled clinical trial}, url = {https://m2.mtmt.hu/api/publication/34794084}, author = {Antal, Márk Ádám and Kiscsatári, Ramóna and Braunitzer, Gábor and Piffkó, József and Varga, Endre and Eliaz, Noam}, doi = {10.1186/s13005-024-00426-0}, journal-iso = {HEAD FACE MED}, journal = {HEAD AND FACE MEDICINE}, volume = {20}, unique-id = {34794084}, issn = {1746-160X}, year = {2024}, eissn = {1746-160X}, orcid-numbers = {Antal, Márk Ádám/0000-0002-4109-9356; Braunitzer, Gábor/0000-0001-8983-5175; Piffkó, József/0000-0001-7119-2685} } @article{MTMT:34450467, title = {Intraoperative Assessment of Resection Margin in Oral Cancer: The Potential Role of Spectroscopy}, url = {https://m2.mtmt.hu/api/publication/34450467}, author = {Vlocskó, Máté and Piffkó, József and Janovszky, Ágnes}, doi = {10.3390/cancers16010121}, journal-iso = {CANCERS}, journal = {CANCERS}, volume = {16}, unique-id = {34450467}, abstract = {In parallel with the increasing number of oncological cases, the need for faster and more efficient diagnostic tools has also appeared. Different diagnostic approaches are available, such as radiological imaging or histological staining methods, but these do not provide adequate information regarding the resection margin, intraoperatively, or are time consuming. The purpose of this review is to summarize the current knowledge on spectrometric diagnostic modalities suitable for intraoperative use, with an emphasis on their relevance in the management of oral cancer. The literature agrees on the sensitivity, specificity, and accuracy of spectrometric diagnostic modalities, but further long-term prospective, multicentric clinical studies are needed, which may standardize the intraoperative assessment of the resection margin and the use of real-time spectroscopic approaches.}, year = {2024}, eissn = {2072-6694}, orcid-numbers = {Piffkó, József/0000-0001-7119-2685} } @article{MTMT:34119738, title = {Comparison of the Three-Dimensional Accuracy of Guided Apicoectomy Performed with a Drill or a Trephine: An In Vitro Study}, url = {https://m2.mtmt.hu/api/publication/34119738}, author = {Kiscsatári, Ramóna and Nagy, Eszter and Szabó, Máté and Braunitzer, Gábor and Piffkó, József and Fráter, Márk Tibor and Antal, Márk Ádám}, doi = {10.3390/app13179642}, journal-iso = {APPL SCI-BASEL}, journal = {APPLIED SCIENCES-BASEL}, volume = {13}, unique-id = {34119738}, abstract = {Guided apicoectomy performed with 3D-printed polymer-based static surgical guides is an emerging trend in endodontic surgery. Static-guided apicoectomy is carried out with either a drill or a trephine. The aim of this in vitro study was to assess the accuracy of osteotomy and apicoectomy performed through a polymer guide, with both drill and trephine, and to compare the accuracy achievable with the two instruments. Six plaster models of a maxilla master model with extracted human maxillary teeth in polymethyl-methacrylate resin were used. The modeled osteotomies were performed in these. The master model was CBCT-scanned, and digital surgical plans were prepared, based on which the surgical guides were printed. The plans contained both drill and trephine apicoectomies. Digital three-dimensional position analysis was performed with dedicated algorithms. A total of 39 drill and 47 trephine osteotomies were analyzed. A statistically significant difference between the two instruments was found only in the global deviation of the distal endpoint, indicating lower deviation for the trephine procedure (1.53 mm vs. 1.31 mm, p = 0.038). Nevertheless, from a clinical perspective, this distinction is inconsequential. The results suggest that, for all practical purposes, the two approaches to apicoectomy allow the same level of accuracy.}, year = {2023}, eissn = {2076-3417}, orcid-numbers = {Braunitzer, Gábor/0000-0001-8983-5175; Piffkó, József/0000-0001-7119-2685; Fráter, Márk Tibor/0000-0002-0365-1613; Antal, Márk Ádám/0000-0002-4109-9356} } @article{MTMT:34035935, title = {Whole-Exome Sequencing Identified Two Novel Pathogenic Mutations in the PTCH1 Gene in BCNS}, url = {https://m2.mtmt.hu/api/publication/34035935}, author = {Pál, Margit and Vetró, Éva and Nagy, Nikoletta and Nagy, Dóra and Ferdinandyné Horváth, Emese and Bokor, Barbara Anna and Varga, Anita and Seres, László and Oláh, Judit Magdolna and Piffkó, József and Széll, Márta}, doi = {10.3390/cimb45070336}, journal-iso = {CURR ISSUES MOL BIOL}, journal = {CURRENT ISSUES IN MOLECULAR BIOLOGY}, volume = {45}, unique-id = {34035935}, issn = {1467-3037}, abstract = {Basal cell nevus syndrome (BCNS, OMIM 109400) is a familial cancer syndrome characterized by the development of numerous basal cell cancers and various other developmental abnormalities, including epidermal cysts of the skin, calcified dural folds, keratocysts of the jaw, palmar and plantar pits, ovarian fibromas, medulloblastomas, lymphomesenteric cysts, and fetal rhabdomyomas. BCNS shows autosomal dominant inheritance and is caused by mutations in the patched 1 (PTCH1) gene and the suppressor of the fused homolog (SUFU) gene. In a few cases, variants of patched 2 (PTCH2) have been found in patients who met the criteria for BCNS. In an investigation of 11 Hungarian families who fulfilled the diagnostic criteria for BCNS, whole-exome sequencing (WES) and multiplex ligation-dependent probe amplification (MLPA) identified two novel pathogenic variants (c.2994C>A; p.Cys998Ter and c.814_818del; p.Asn272SerfsTer11), one recently identified variant (c.1737_1745del p.Val580_Val582del), and three recurrent disease-causing variants of the PTCH1 gene with a diagnosis rate of 63.6%. Disease-causing variants were not found for the SUFU and PTCH2 genes. These applied methods could not fully elucidate the genetic background of all the BCNS cases that we investigated. To uncover the missing heritability of BCNS, whole-genome sequencing or an epigenetic approach might be considered in the future.}, year = {2023}, eissn = {1467-3045}, pages = {5293-5304}, orcid-numbers = {Piffkó, József/0000-0001-7119-2685; Széll, Márta/0000-0002-0730-714X} } @article{MTMT:33790411, title = {A novel approach for determining instantaneous centers of rotation of the mandible with an intraoral scanner: A preliminary study}, url = {https://m2.mtmt.hu/api/publication/33790411}, author = {Sáfrány-Fárk, Árpád and Laczi, Balázs and Nagy, Antal and Lengyel, Laura and Piffkó, József and Segatto, Emil}, doi = {10.1371/journal.pone.0285162}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {18}, unique-id = {33790411}, issn = {1932-6203}, year = {2023}, eissn = {1932-6203}, orcid-numbers = {Sáfrány-Fárk, Árpád/0000-0002-9345-5164; Nagy, Antal/0000-0003-4558-8330; Piffkó, József/0000-0001-7119-2685; Segatto, Emil/0000-0002-5817-2855} } @article{MTMT:33680226, title = {Challenges in the complex management of neglected cutaneous melanomas in the head and neck area: a single center experience}, url = {https://m2.mtmt.hu/api/publication/33680226}, author = {Lázár, Péter and Tóth-Molnár, Edit and Bende, Balázs and Vass, Gábor and Baltás, Eszter and Paczona, Róbert and Varga, Erika and Piffkó, József and Kemény, Lajos and Oláh, Judit Magdolna and Kis, Erika}, doi = {10.3390/jcm12051910}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {12}, unique-id = {33680226}, abstract = {Familiar controversies in the management of head and neck melanomas are more remarkable in locally advanced cases, and they represent a treatment challenge both surgically and oncologically. In our retrospective study, patients with surgically treated primary malignant melanoma of the head and neck region larger than 3 cm in diameter were included. Five patients met our inclusion criteria. In all cases, wide excision and immediate reconstruction were performed without sentinel lymph node biopsy. The defect on the scalp was covered by a split skin graft, with local flaps chosen for reconstruction on the face on an individual basis. After a 2–6 year follow-up, a good oncological, functional, and esthetic result was achieved. Our results show that in the case of large, locally advanced melanomas, surgical treatment still plays a crucial role that can provide long-term local control and support the effect of systemic treatment.}, year = {2023}, eissn = {2077-0383}, orcid-numbers = {Tóth-Molnár, Edit/0000-0001-7989-1616; Vass, Gábor/0000-0003-0787-8679; Baltás, Eszter/0000-0003-0357-7393; Piffkó, József/0000-0001-7119-2685; Kemény, Lajos/0000-0002-2119-9501} } @article{MTMT:33194226, title = {Odontogén tályogok diagnosztikája és kezelése a nemzetközi ajánlások tükrében [Current approaches to the diagnosis and management of odontogenic abscesses]}, url = {https://m2.mtmt.hu/api/publication/33194226}, author = {Vetró, Éva and Vlocskó, Máté and Piffkó, József and Janovszky, Ágnes}, doi = {10.1556/650.2022.32587}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {163}, unique-id = {33194226}, issn = {0030-6002}, abstract = {A wide scale of medical professionals including general practitioners, dentists, maxillofacial surgeons, otolaryngologists or even emergency physicians frequently encounter patients suffering from abscesses of odontogenic origin. These dental infections spreading along the fascial planes into the adjacent anatomical spaces or by the lymphatic vessels and veins may result in life-threatening situations. It is essential to prevent and - in the case of an evolved disease pattern - to treat them properly, since improper or delayed treatment may entail avoidable burdens on the healthcare system. Our aim was to review the current literature regarding the development, diagnostics and treatment of odontogenic infections. A review of the English and Hungarian literature was performed. Considerations regarding the surgical management of dental abscesses have well-tried, traditional routes. Prompt intervention is considered mandatory with surgical decompression of the swelling by performing incision and drainage. A rapid improvement of radiology has provided the possibility to realize and avoid fatal consequences of this disorder. The administration route, necessity and duration of empiric antibiotic therapy are still "debated", protocols vary across studies. Based on inconsistency in findings among the studies and lack of high-quality prospective studies, future research should evaluate evidence-based and effective management of dental abscesses. Orv Hetil. 2022; 163(37): 1455-1463.}, keywords = {Odontogenic abscess; Empiric antibiotic therapy; contrast-enhanced head and neck CT; deep spaces of the head and neck; empirikus antibiotikumkezelés; kontrasztos koponya- és nyaki CT-vizsgálat; nyaki spatiumok; odontogén abscessus}, year = {2022}, eissn = {1788-6120}, pages = {1455-1463}, orcid-numbers = {Piffkó, József/0000-0001-7119-2685} } @article{MTMT:33152214, title = {A szájüregi daganatok korszerű kezelése}, url = {https://m2.mtmt.hu/api/publication/33152214}, author = {Paczona, Róbert and Csenki, Melinda and Hideghéty, Katalin and Piffkó, József}, journal-iso = {KLINIKAI ONKOLÓGIA}, journal = {KLINIKAI ONKOLÓGIA}, volume = {9}, unique-id = {33152214}, issn = {2064-5058}, year = {2022}, pages = {253-261}, orcid-numbers = {Hideghéty, Katalin/0000-0001-7080-2365; Piffkó, József/0000-0001-7119-2685} } @article{MTMT:33055740, title = {Állcsontnövekedési zavarokra specifikus életminőség-kérdőív magyar nyelvű adaptálása [Translation and validation of the Hungarian version of the Orthognathic Quality of Life Questionnaire]}, url = {https://m2.mtmt.hu/api/publication/33055740}, author = {Mucsi, Marietta and Mányai, A. and Mészáros, Bence and Piffkó, József and Seres, László}, doi = {10.1556/650.2022.32533}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {163}, unique-id = {33055740}, issn = {0030-6002}, year = {2022}, eissn = {1788-6120}, pages = {1275-1280}, orcid-numbers = {Mészáros, Bence/0000-0003-3522-6723; Piffkó, József/0000-0001-7119-2685} } @mastersthesis{MTMT:32858723, title = {Clinical Efficiency of Different Regenerative Surgical Approaches to Restore Vertical Defects of the Mandible and Maxilla [A mandibula és a maxilla vertikális defektusainak helyreállítására irányuló egyes regeneratív sebészeti megoldások klinikai hatékonysága]}, url = {https://m2.mtmt.hu/api/publication/32858723}, author = {Sass, Tamás}, doi = {10.14232/phd.11170}, publisher = {SZTE}, unique-id = {32858723}, year = {2022} }