TY - JOUR AU - Ko, Young-Chang AU - Lee, Jungwon AU - Urbán, István András AU - Seol, Yang-Jo AU - Lee, Yong-Moo AU - Koo, Ki-Tae TI - The adjunctive effect of polydeoxyribonucleotide on bone formation in alveolar ridge preservation: A pre-clinical in vivo study JF - JOURNAL OF CLINICAL PERIODONTOLOGY J2 - J CLIN PERIODONTOL PY - 2024 PG - 10 SN - 0303-6979 DO - 10.1111/jcpe.13988 UR - https://m2.mtmt.hu/api/publication/34818825 ID - 34818825 AB - AimThis study investigated the adjunctive effect of polydeoxyribonucleotide (PDRN) on bone formation in alveolar ridge preservation (ARP) sockets.Materials and MethodsBoth mandibular second, third and fourth premolars of eight beagle dogs were randomly divided into ARP and ARP/PDRN groups. Following tooth extraction, ARP procedures were conducted using collagenized alloplastic graft material and bilayer collagen membrane soaked with normal saline (ARP group) or PDRN (ARP/PDRN group) for 10 min before application. Both groups were also randomly allocated to 2-, 4- or 12-week healing subgroups. The primary endpoint of this study was to compare histomorphometric differences between ARP and ARP/PDRN. The secondary endpoints of this study were to compare micro-CT analysis and three-dimensional volumetric measurement between the two groups.ResultsIn the histomorphometric analysis, the ARP/PDRN group exhibited greater new bone formation at coronal, middle and total position compared with the ARP group at 2-week healing. The number of newly formed blood vessels was higher in the ARP/PDRN group than in the ARP group at 2- and 4-week healing. In micro-CT analysis, the mean new bone volume/total bone volume between ARP and ARP/PDRN was statistically significant at 2-week healing. Ridge volume alterations were significantly decreased in the ARP/PDRN group during entire healing time compared with the ARP group, especially on the buccal side.ConclusionsThe application of PDRN in ARP might provide additional benefits for early bone regeneration and maintenance of buccal ridge volume. LA - English DB - MTMT ER - TY - JOUR AU - Lászlófy, Csaba AU - Joób-Fancsaly, Árpád AU - Baráth, Zoltán Lajos TI - Csontpótlás és sinus elevatio: csont vagy csontpótló anyag? Csontpótlás a mindennapi gyakorlatban = Grefa osoasă și ridicarea sinusurilor: os sau substitut osos? Substituenți osoși în practica de zi cu zi = Bone grafting and sinus elevation: Bone or bone substitute? Bone substitutes in everyday practice JF - BULLETIN OF MEDICAL SCIENCES / ORVOSTUDOMÁNYI ÉRTESÍTŐ J2 - ORVOSTUDOMÁNYI ÉRTESÍTŐ VL - 97 PY - 2024 IS - 1. Klnsz. SP - 27 EP - 27 PG - 1 SN - 1453-0953 UR - https://m2.mtmt.hu/api/publication/34806245 ID - 34806245 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Lászlófy, Csaba AU - Joób-Fancsaly, Árpád AU - Baráth, Zoltán Lajos TI - Fogatlan szájüreg implantációs-protetikai ellátása: 25 éves az ALL-ON® kezelési koncepció = Îngrijirea implanto-protetică a cavității edentate: 25 de ani de concept de tratament ALL-ON-4® = Complex implant-prosthetic treatment of the edentulous oral cavity: 25 years of the ALL-ON® treatment concept JF - BULLETIN OF MEDICAL SCIENCES / ORVOSTUDOMÁNYI ÉRTESÍTŐ J2 - ORVOSTUDOMÁNYI ÉRTESÍTŐ VL - 97 PY - 2024 IS - 1. Klnsz. SP - 27 EP - 27 PG - 1 SN - 1453-0953 UR - https://m2.mtmt.hu/api/publication/34806243 ID - 34806243 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Antal, Márk Ádám AU - Kiscsatári, Ramóna AU - Braunitzer, Gábor AU - Piffkó, József AU - Varga, Endre AU - Eliaz, Noam TI - Assessment of a novel electrochemically deposited smart bioactive trabecular coating (SBTC®): a randomized controlled clinical trial JF - HEAD AND FACE MEDICINE J2 - HEAD FACE MED VL - 20 PY - 2024 IS - 1 PG - 14 SN - 1746-160X DO - 10.1186/s13005-024-00426-0 UR - https://m2.mtmt.hu/api/publication/34794084 ID - 34794084 LA - English DB - MTMT ER - TY - JOUR AU - Rajnics, Zsolt AU - Pammer, Dávid AU - Kőnigné Péter, Anikó AU - Turzó, Kinga Mónika AU - Marada, Gyula AU - Radnai, Márta TI - Push-Out Bond Strength of Glass Fiber Endodontic Posts with Different Diameters JF - MATERIALS J2 - MATERIALS VL - 17 PY - 2024 IS - 7 PG - 10 SN - 1996-1944 DO - 10.3390/ma17071492 UR - https://m2.mtmt.hu/api/publication/34771068 ID - 34771068 N1 - Faculty of Medicine, Dental School, University of Pécs, Pécs, 7623, Hungary Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, 1111, Hungary Institute of Bioanalysis, Medical School, University of Pécs, Pécs, 7624, Hungary Department of Prosthodontics, Faculty of Dentistry, University of Szeged, Szeged, 6720, Hungary Export Date: 22 April 2024 Correspondence Address: Rajnics, Z.; Faculty of Medicine, Hungary; email: rajnics.zsolt@pte.hu AB - (1) Background: The retention of intraradicular posts is an important factor for the prognosis of endodontically treated teeth. The purpose of this study was to evaluate the push-out bond strength (PBS) of the posts relating to their diameter and region of the root. (2) Methods: A total of 40 premolar teeth (decoronated and root canal-filled) were divided into four groups (n = 10). After post-space preparation, different sizes (1.0, 1.2, 1.5, and 2.0 mm) of glass fiber posts were luted with resin cement into the root canals. After placement, 2 mm thick slices were cut from the roots according to their apical, middle, and coronal regions (n = 116). Push-out tests were carried out in a universal testing machine on each slice. A statistical evaluation of the data was applied. (3) Results: When comparing the diameter, the 2.0 mm posts had the highest PBS (111.99 ± 10.40 N), while the 1.0 mm posts had the lowest PBS (99.98 ± 8.05 N). Divided by the surface of the bonded area, the average PBS value was the highest for the 1.0 mm posts (18.20 ± 1.67 MPa) and the lowest for the 2.0 mm posts (12.08 ± 1.05 MPa). (4) Conclusions: Within the limitations of the study, when comparing the regions of the roots, no significant differences were found among the PBS values of the three regions (p = 0.219). When comparing the diameters, significant differences were shown between the PBS values of the four groups (p = 0.023 and p = 0.003, respectively). LA - English DB - MTMT ER - TY - JOUR AU - Sadid‐Zadeh, Ramtin AU - Lin, Kevin AU - Li, Rui AU - Nagy, Katalin TI - Fracture strength of screw‐retained zirconia crowns assembled on zirconia and titanium implants JF - JOURNAL OF PROSTHODONTICS-IMPLANT ESTHETIC AND RECONSTRUCTIVE DENTISTRY J2 - J PROSTHODONT VL - 33 PY - 2024 IS - 3 SP - 273 EP - 280 PG - 8 SN - 1059-941X DO - 10.1111/jopr.13683 UR - https://m2.mtmt.hu/api/publication/34752686 ID - 34752686 LA - English DB - MTMT ER - TY - JOUR AU - Kushkevych, Ivan AU - Martínková, Kristýna AU - Mráková, Lenka AU - Giudici, Francesco AU - Baldi, Simone AU - Novak, David AU - Gajdács, Márió AU - Vítězová, Monika AU - Dordevic, Dani AU - Amedei, Amedeo AU - Rittmann, Simon K.-M. R. TI - Comparison of microbial communities and the profile of sulfate-reducing bacteria in patients with ulcerative colitis and their association with bowel diseases: a pilot study JF - MICROBIAL CELL J2 - MICROBIAL CELL VL - 11 PY - 2024 IS - 1 SP - 79 EP - 89 PG - 11 SN - 2311-2638 DO - 10.15698/mic2024.03.817 UR - https://m2.mtmt.hu/api/publication/34741193 ID - 34741193 AB - Considerable evidence has accumulated regarding the molecular relationship between gut microbiota (GM) composition and the onset (clinical presentation and prognosis of ulcerative colitis (UC)). In addition, it is well documented that short-chain fatty acid (SCFA)-producing bacteria may play a fundamental role in maintaining an anti-inflammatory intestinal homeostasis, but sulfate- and sulfite reducing bacteria may be responsible for the production of toxic metabolites, such as hydrogen sulfide and acetate. Hence, the present study aimed to assess the GM composition – focusing on sulfate-reducing bacteria (SRB) – in patients with severe, severe-active and moderate UC. Each one of the six enrolled patients provided two stool samples in the following way: one sample was cultivated in a modified SRB-medium before 16S rRNA sequencing and the other was not cultivated. Comparative phylogenetic analysis was conducted on each sample. Percentage of detected gut microbial genera showed considerable variation based on the patients’ disease severity and cultivation in the SRB medium. In detail, samples without cultivation from patients with moderate UC showed a high abundance of the genera Bacteroides, Bifidobacterium and Ruminococcus, but after SRB cultivation, the dominant genera were Bacteroides, Klebsiella and Bilophila. On the other hand, before SRB cultivation, the main represented genera in patients with severe UC were Escherichia-Shigella, Proteus, Methanothermobacter and Methanobacterium. However, after incubation in the SRB medium Bacteroides, Proteus, Alistipes and Lachnoclostridium were predominant. Information regarding GM compositional changes in UC patients may aid the development of novel therapeutic strategies (e.g., probiotic preparations containing specific bacterial strains) to counteract the mechanisms of virulence of harmful bacteria and the subsequent inflammatory response that is closely related to the pathogenesis of inflammatory bowel diseases. LA - English DB - MTMT ER - TY - JOUR AU - Lászlófy, Csaba AU - Fazekas, Gyorgy AU - Baráth, Zoltán Lajos AU - Vajó, Zoltán TI - Evaluation of Vaccine Immunogenicity—Correlates to Real-World Protection: Influenza JF - VIRUSES J2 - VIRUSES-BASEL VL - 16 PY - 2024 IS - 3 PG - 11 SN - 1999-4915 DO - 10.3390/v16030441 UR - https://m2.mtmt.hu/api/publication/34734568 ID - 34734568 LA - English DB - MTMT ER - TY - JOUR AU - Aghasizadeh Sherbaf, Reza AU - Kaposvári, George Michel AU - Nagy, Katalin AU - Álmos, Péter Zoltán AU - Baráth, Zoltán Lajos AU - Matusovits, Danica TI - Oral Health Status and Factors Related to Oral Health in Patients with Schizophrenia: A Matched Case-Control Observational Study JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 6 PG - 13 SN - 2077-0383 DO - 10.3390/jcm13061584 UR - https://m2.mtmt.hu/api/publication/34728780 ID - 34728780 LA - English DB - MTMT ER - TY - JOUR AU - Pallós, Péter AU - Gajdács, Márió AU - Zsoldiné Urbán, Edit AU - Szabados, Yvett AU - Szalai, Klaudia AU - Hevesi, Lívia AU - Horváth, Anna AU - Kuklis, Anna AU - Morjaria, Devina AU - Iffat, Wajiha AU - Hetta, Helal F. AU - Piredda, Nicola AU - Donadu, Matthew Gavino TI - Characterization of antibiotic and disinfectant susceptibility in biofilm-forming Acinetobacter baumannii: A focus on environmental isolates JF - EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY J2 - EUR J MICROBIOL IMMU PY - 2024 SN - 2062-509X DO - 10.1556/1886.2024.00014 UR - https://m2.mtmt.hu/api/publication/34721811 ID - 34721811 N1 - Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Tisza Lajos krt. 64-66., Szeged, 6720, Hungary Department of Medical Microbiology and Immunology, University of Pécs Medical School, Szigeti út 12, Pécs, 7624, Hungary Department of Pharmaceutics, Dow College of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Dow University of Health Sciences, OJHA Campus, Karachi, Pakistan Department of Natural Products and Alternative Medicine, Division of Microbiology and Immunology, Faculty of Pharmacy, University of Tabuk, Tabuk, 71491, Saudi Arabia Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt Radiology Unit, Giovanni Paolo II Hospital, ASL Gallura, Olbia, 07026, Italy Hospital Pharmacy, Giovanni Paolo II Hospital, ASL Gallura, Olbia, 07026, Italy Department of Medicine, Surgery and Pharmacy, Scuola di Specializzazione in Farmacia Ospedaliera, University of Sassari, Sassari, 07100, Italy Export Date: 19 April 2024 Correspondence Address: Gajdács, M.; Department of Oral Biology and Experimental Dental Research, Tisza Lajos krt. 64-66., Hungary; email: mariopharma92@gmail.com Funding details: Nemzeti Kutatási, Fejlesztési és Innovaciós Alap, NKFIA, ÚNKP-23-1-SZTE-146 Funding text 1: A.K. was supported by the New National Excellence Program of the Ministry for Culture and Innovation from the source of the National Research Development and Innovation Fund (ÚNKP-23-1-SZTE-146). The authors are thankful for the support of the Study Group for Dental Research Methodology and Health Sciences, University of Szeged. AB - The clinical role of Acinetobacter baumannii has been highlighted in numerous infectious syndromes with a high mortality rate, due to the high prevalence of multidrug-resistant (MDR) isolates. The treatment and eradication of this pathogen is hindered by biofilm-formation, providing protection from noxious environmental factors and antimicrobials. The aim of this study was to assess the antibiotic susceptibility, antiseptic susceptibility and biofilm-forming capacity using phenotypic methods in environmental A. baumannii isolates. One hundred and fourteen ( n = 114) isolates were collected, originating from various environmental sources and geographical regions. Antimicrobial susceptibility testing was carried out using the disk diffusion method, while antiseptic susceptibility was performed using the agar dilution method. Determination of biofilm-forming capacity was carried out using a microtiter-plate based method. Resistance in environmental A. baumannii isolates were highest for ciprofloxacin (64.03%, n = 73), levofloxacin (62.18%, n = 71) and trimethoprim-sulfamethoxazole (61.40%, n = 70), while lowest for colistin (1.75%, n = 2). Efflux pump overexpression was seen in 48.25% of isolates ( n = 55), 49.12% ( n = 56) were classified as MDR. 6.14% ( n = 7), 9.65% ( n = 11), 24.65% ( n = 28) and 59.65% ( n = 68) of isolates were non-biofilm producers, weak, medium, and strong biofilm producers, respectively. No significant differences were observed between non-MDR vs. MDR isolates regarding their distribution of biofilm-producers ( P = 0.655). The MIC ranges for the tested antiseptics were as follows: benzalkonium chloride 16–128 μg mL −1 , chlorhexidine digluconate 4–128 μg mL −1 , formaldehyde 64–256 μg mL −1 and triclosan 2–16 μg mL −1 , respectively. The conscientious use of antiseptics, together with periodic surveillance, is essential to curb the spread of these bacteria, and to maintain current infection prevention capabilities. LA - English DB - MTMT ER -