TY - JOUR AU - Seres, László AU - Varga, Norbert AU - Juhász, Ádám AU - Csapó, Edit TI - Novel approaches to monitoring the formation of self-assembled colloids composed of cationic surfactants and alginate polysaccharide JF - SURFACES AND INTERFACES J2 - SURF INTERFACES VL - 49 PY - 2024 SP - 104430 SN - 2468-0230 DO - 10.1016/j.surfin.2024.104430 UR - https://m2.mtmt.hu/api/publication/34832848 ID - 34832848 LA - English DB - MTMT ER - TY - JOUR AU - Hassan, Alharith A. A. AU - Sovány, Tamás AU - Pamlényi, Krisztián AU - Deák, Martin AU - Varga, Viktória AU - Csapó, Edit AU - Regdon, Géza (ifj.) AU - Pannonhalminé Csóka, Ildikó AU - Kristó, Katalin TI - QbD Approach-Based Preparation and Optimization of Hydrophobic Ion-Pairing Complex of Lysozyme with Sodium Dodecyl Sulphate to Enhance Stability in Lipid-Based Carriers JF - PHARMACEUTICS J2 - PHARMACEUTICS VL - 16 PY - 2024 IS - 5 SP - 589 SN - 1999-4923 DO - 10.3390/pharmaceutics16050589 UR - https://m2.mtmt.hu/api/publication/34832111 ID - 34832111 AB - Hydrophobic ion pairing (HIP) complexation was found to be an efficient approach in modulating the release and enhancing the stability and encapsulation of hydrophilic macromolecules such as proteins in hydrophobic nano/microcarriers. The present work strives to develop and optimize the preparation of the HIP complex of the antimicrobial enzyme lysozyme (LYZ) with the ion-pairing agent (IPA) sodium dodecyl sulphate (SDS) relying on the quality-by-design (QbD) approach. The quality target product profile (QTPP) includes the achievement of maximal lipophilicity in a reversible manner to enable the maintenance of biological activity. The related critical quality attributes (CQAs) were defined as complexation efficacy, complex stability, enzyme recovery and activity. Three risk assessment (RA) tools were used to identify and rank the critical process parameters (CPPs) and critical material attributes (CMAs). From this assessment, the pH of the medium, LYZ:SDS molar ratio and drying conditions were determined as high-risk factors that need to be investigated. To the best of our knowledge, for the first time, electrostatic titration was used as a smart approach to determine the optimum molar ratio at different pH values. Based on the predefined CQAs, pH 8 with an LYZ/SDS molar ratio of 1:8 was found to be the optimal condition for complexation efficiency and recovery (%) of a biologically active enzyme. A cost-effective drying process based on a ventilated oven was developed, which resulted in complex qualities comparable to those obtained by the commonly used freeze-drying method. In a nutshell, the optimum conditions for the preparation of the LYZ/SDS HIP complex were efficiently facilitated by the rational application of QbD principles and the utilization of efficient electrostatic titration and ventilated oven-drying methods. LA - English DB - MTMT ER - TY - JOUR AU - Petrovszki, Judit AU - Szilassi, Péter AU - Erős, Tibor TI - Mass tourism generated urban land expansion in the catchment of Lake Balaton, Hungary – analysis of long-term changes in characteristic socio-political periods JF - LAND USE POLICY J2 - LAND USE POLICY VL - 142 PY - 2024 SP - 107185 SN - 0264-8377 DO - 10.1016/j.landusepol.2024.107185 UR - https://m2.mtmt.hu/api/publication/34830186 ID - 34830186 LA - English DB - MTMT ER - TY - JOUR AU - Monis Ayyub, Mohd AU - Kormányos, Attila AU - Endrődi, Balázs AU - Janáky, Csaba TI - Electrochemical carbon monoxide reduction at high current density: Cell configuration matters JF - CHEMICAL ENGINEERING JOURNAL J2 - CHEM ENG J VL - online PY - 2024 SP - 151698 SN - 1385-8947 DO - 10.1016/j.cej.2024.151698 UR - https://m2.mtmt.hu/api/publication/34826023 ID - 34826023 LA - English DB - MTMT ER - TY - JOUR AU - Balog, Ádám AU - Kecsenovity, Egon AU - Samu, Gergely Ferenc AU - He, Jie AU - Fekete, Dávid AU - Janáky, Csaba TI - Paired photoelectrochemical conversion of CO2/H2O and glycerol at high rate JF - NATURE CATALYSIS J2 - NAT CATAL PY - 2024 SN - 2520-1158 DO - 10.1038/s41929-024-01134-3 UR - https://m2.mtmt.hu/api/publication/34825908 ID - 34825908 AB - Photoelectrochemistry holds the promise of directly converting sunlight to valuable chemical products. Photoelectrochemical (PEC) methods, however, lag behind their electrochemical counterparts in terms of current density. In this work, we demonstrate that, by using concentrated sunlight, we can achieve current densities similar to electrochemical methods, but with lower energy input. Specifically, we combined the direct PEC oxidation of glycerol with the dark hydrogen evolution or CO 2 reduction in a membrane-separated continuous-flow PEC cell. We achieved over 110 mA cm −2 photocurrent density, which is at least an order of magnitude larger than those typically reported in the literature. We demonstrated that the product distribution of glycerol oxidation is notably different in PEC and electrochemical scenarios at the same current density, and the parasitic oxygen evolution reaction can be suppressed in the PEC case. This approach raises opportunities to drive complex electrochemical reactions in a more selective manner. LA - English DB - MTMT ER - TY - CHAP AU - Kitti, Tari AU - Turbat, Adiyadolgor AU - Enkh-Amgalan, Jigjiddorj AU - Varga, Mónika AU - Vágvölgyi, Csaba AU - Szekeres, András ED - Ingrid, Melinda Gyalai ED - Szilárd, Czóbel TI - Revealing secondary metabolite alterations in fungal endophyte secretom T2 - 21st Wellmann International Scientific Conference PB - University of Szeged Faculty of Agriculture CY - Hódmezővásárhely SN - 9789633069806 PY - 2024 SP - 118 UR - https://m2.mtmt.hu/api/publication/34825686 ID - 34825686 LA - English DB - MTMT ER - TY - CHAP AU - Dániel, Hercegfalvi AU - Varga, Mónika AU - Allaga, Henrietta AU - Kredics, László AU - Vágvölgyi, Csaba AU - Szekeres, András ED - Ingrid, Melinda Gyalai ED - Szilárd, Czóbel TI - Analysis of surfactin components produced by Bacillus strains isolated from environmental samples T2 - 21st Wellmann International Scientific Conference PB - University of Szeged Faculty of Agriculture CY - Hódmezővásárhely SN - 9789633069806 PY - 2024 SP - 111 UR - https://m2.mtmt.hu/api/publication/34825669 ID - 34825669 LA - English DB - MTMT ER - TY - CHAP AU - Papp, Dóra Anna AU - Kitti, Tari AU - Kozma-Bognárné Hamari, Zsuzsanna AU - Szekeres, András AU - Vágvölgyi, Csaba AU - Varga, Mónika ED - Ingrid, Melinda Gyalai ED - Szilárd, Czóbel TI - Investigation of the metabolomic profile of Pseudomonas strains T2 - 21st Wellmann International Scientific Conference PB - University of Szeged Faculty of Agriculture CY - Hódmezővásárhely SN - 9789633069806 PY - 2024 SP - 60 UR - https://m2.mtmt.hu/api/publication/34825666 ID - 34825666 LA - English DB - MTMT ER - TY - JOUR AU - Kormányos, Attila AU - Szirmai, Adrienn AU - Endrődi, Balázs AU - Janáky, Csaba TI - Stable Operation of Paired CO2 Reduction/Glycerol Oxidation at High Current Density JF - ACS CATALYSIS J2 - ACS CATAL PY - 2024 SN - 2155-5435 DO - 10.1021/acscatal.3c05952 UR - https://m2.mtmt.hu/api/publication/34823504 ID - 34823504 LA - English DB - MTMT ER - TY - JOUR AU - Fazekas, Ákos Ferenc AU - Gyulavári, Tamás AU - Ágoston, Áron AU - Janovák, László AU - Heszlerné Kopniczky, Judit AU - László, Zsuzsanna AU - Veréb, Gábor TI - Enhanced Photocatalytic and Filtration Performance of TiO2-Ag Composite-Coated Membrane Used for the Separation of Oil Emulsions JF - SEPARATIONS J2 - SEPARATIONS VL - 11 PY - 2024 IS - 4 SP - 112 SN - 2297-8739 DO - 10.3390/separations11040112 UR - https://m2.mtmt.hu/api/publication/34823133 ID - 34823133 AB - Polyvinylidene fluoride (PVDF) membranes were coated with TiO2 and TiO2-Ag to enhance their efficiency for oil-in-water emulsion separation. The photocatalytic activities of the two modified membranes and their filtration performances were compared in detail. The significantly enhanced photocatalytic activity of the TiO2-Ag composite was proved using a methyl orange (MO) solution (c = 10−5 M) and a crude oil emulsion (c = 50 mg·L−1). The TiO2-Ag-coated membrane reduced the MO concentration by 87%, whereas the TiO2-modified membrane reached only a 46% decomposition. The photocatalytic reduction in the chemical oxygen demand of the emulsion was also ~50% higher using the TiO2-Ag-coated membrane compared to that of the TiO2-coated membrane. The photoluminescence measurements demonstrated a reduced electron/hole recombination, achieved by the Ag nanoparticle addition (TiO2-Ag), which also explained the enhanced photocatalytic activity. A significant improvement in the oil separation performance with the TiO2-Ag-coated membrane was also demonstrated: a substantial increase in the flux and flux recovery ratio (up to 92.4%) was achieved, together with a notable reduction in the flux decay ratio and the irreversible filtration resistance. Furthermore, the purification efficiency was also enhanced (achieving 98.5% and 99.9% COD and turbidity reductions, respectively). Contact angle, zeta potential, scanning electron microscopy (SEM), and atomic force microscopy (AFM) measurements were carried out to explain the results. SEM and AFM images revealed that on the TiO2-Ag-coated membrane, a less aggregated, more continuous, homogeneous, and smoother nanolayer was formed due to the ~50% more negative zeta potential of the TiO2-Ag nanocomposite compared to that of the TiO2. In summary, via Ag addition, a sufficiently hydrophilic, beneficially negatively charged, and homogeneous TiO2-Ag-coated PVDF membrane surface was achieved, which resulted in the presented advantageous filtration properties beyond the photocatalytic activity enhancement. LA - English DB - MTMT ER -