@article{MTMT:34474549, title = {Microstructural differences in migraine: A diffusion-tensor imaging study}, url = {https://m2.mtmt.hu/api/publication/34474549}, author = {Dobos, Dóra and Kökönyei, Gyöngyi and Gyebnár, Gyula and Szabó, Edina and Kocsel, Natália and Galambos, Attila and Gecse, Kinga and Baksa, Dániel and Kozák, Lajos Rudolf and Juhász, Gabriella}, doi = {10.1177/03331024231216456}, journal-iso = {CEPHALALGIA}, journal = {CEPHALALGIA}, volume = {43}, unique-id = {34474549}, issn = {0333-1024}, year = {2023}, eissn = {1468-2982}, orcid-numbers = {Dobos, Dóra/0000-0002-2291-8854; Kökönyei, Gyöngyi/0000-0001-6750-2644; Szabó, Edina/0000-0003-4087-5373; Kocsel, Natália/0000-0001-6892-796X; Galambos, Attila/0000-0002-4587-9288; Gecse, Kinga/0000-0002-3512-2572; Baksa, Dániel/0000-0002-7826-9179; Kozák, Lajos Rudolf/0000-0003-0368-3663; Juhász, Gabriella/0000-0002-5975-4267} } @article{MTMT:33895542, title = {Központi idegrendszeri vasculitises eseteink retrospektív vizsgálata}, url = {https://m2.mtmt.hu/api/publication/33895542}, author = {Dobner, Sarolta and Szabó, Léna and Hudák, Mária and Benke, Péter and Constantin, Tamás and Varga, Edit and Liptai, Zoltán}, journal-iso = {IDEGGYÓGY SZEMLE PROC}, journal = {IDEGGYÓGYÁSZATI SZEMLE PROCEEDINGS / CLINICAL NEUROSCIENCE PROCEEDINGS}, volume = {7}, unique-id = {33895542}, issn = {2498-6240}, year = {2022}, pages = {193}, orcid-numbers = {Szabó, Léna/0000-0003-2621-1378; Constantin, Tamás/0000-0002-0146-3045; Varga, Edit/0000-0002-0215-0702} } @article{MTMT:32754998, title = {Diagnostic value of MRI in the presurgical evaluation of patients with epilepsy. influence of field strength and sequence selection: a systematic review and meta-analysis from the E-PILEPSY Consortium.}, url = {https://m2.mtmt.hu/api/publication/32754998}, author = {Rados, Matea and Mouthaan, Brian and Barsi, Péter and Carmichael, David and Heckemann, Rolf A and Kelemen, Anna and Kobulashvili, Teia and Kuchukhidze, Giorgi and Marusic, Petr and Minkin, Krasimir and Tisdall, Martin and Trinka, Eugen and Veersema, Tim and Vos, Sjoerd B and Wagner, Jan and Braun, Kees and van Eijsden, Pieter}, doi = {10.1684/epd.2021.1399}, journal-iso = {EPILEPTIC DISORD}, journal = {EPILEPTIC DISORDERS}, volume = {24}, unique-id = {32754998}, issn = {1294-9361}, abstract = {MRI is a cornerstone in presurgical evaluation of epilepsy. Despite guidelines, clinical practice varies. In light of the E-PILEPSY pilot reference network, we conducted a systematic review and meta-analysis on the diagnostic value of MRI in the presurgical evaluation of epilepsy patients. We included original research articles on diagnostic value of higher MRI field strength and guideline-recommended and additional MRI sequences in detecting an epileptogenic lesion in adult or paediatric epilepsy surgery candidates. Lesion detection rate was used as a metric in meta-analysis. Eighteen studies were included for MRI field strength and 25 for MRI sequences, none were free from bias. In patients with normal MRI at lower-field strength, 3T improved lesion detection rate by 18% and 7T by 23%. Field strengths higher than 1.5T did not have higher lesion detection rates in patients with hippocampal sclerosis (HS). The lesion detection rate of epilepsy-specific MRI protocols was 83% for temporal lobe epilepsy (TLE) patients. Dedicated MRI protocols and evaluation by an experienced epilepsy neuroradiologist increased lesion detection. For HS, 3DT1, T2, and FLAIR each had a lesion detection rate at around 90%. Apparent diffusion coefficient indices had a lateralizing value of 33% for TLE. DTI fractional anisotropy and mean diffusivity had a localizing value of 8% and 34%. A dedicated MRI protocol and expert evaluation benefits lesion detection rate in epilepsy surgery candidates. If patients remain MRI negative, imaging at higher-field strength may reveal lesions. In HS, apparent diffusion coefficient indices may aid lateralization and localization more than increasing field strength. DTI can add further diagnostic information. For other additional sequences, the quality and number of studies is insufficient to draw solid conclusions. Our findings may be used as evidence base for developing new high-quality MRI studies and clinical guidelines.}, keywords = {Magnetic Resonance Imaging; Diagnostic Imaging; REFRACTORY EPILEPSY; Lesion}, year = {2022}, eissn = {1950-6945}, pages = {323-342}, orcid-numbers = {Barsi, Péter/0000-0002-3574-9973; Kelemen, Anna/0000-0003-3942-3409} } @article{MTMT:32704613, title = {Factors affecting postural instability after more than one-year bilateral subthalamic stimulation in Parkinson's disease: A cross-sectional study}, url = {https://m2.mtmt.hu/api/publication/32704613}, author = {Kelemen, Andrea Judit and Halász, László and Erőss, Loránd and Rudas, Gábor and Muthuraman, Muthuraman and Zádori, Dénes and Laczó, Bence and Kis, Dávid and Klivényi, Péter and Fekete, Gábor and Bognár, László and Bereczki, Dániel and Tamás, Gertrúd}, doi = {10.1371/journal.pone.0264114}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {17}, unique-id = {32704613}, issn = {1932-6203}, abstract = {Balance impairment in Parkinson's disease is multifactorial and its changes due to subthalamic stimulation vary in different studies.We aimed to analyze the combination of predictive clinical factors of balance impairment in patients with Parkinson's disease treated with bilateral subthalamic stimulation for at least one year.We recruited 24 patients with Parkinson's disease treated with bilateral subthalamic stimulation and 24 healthy controls. They wore an Opal monitor (APDM Inc.) consisting of three-dimensional gyroscopes and accelerometers in the lumbar region. We investigated four stimulation conditions (bilateral stimulation OFF, bilateral stimulation ON, and unilateral right- and left-sided stimulation ON) with four tests: stance on a plain ground with eyes open and closed, stance on a foam platform with eyes open and closed. Age, disease duration, the time elapsed after implantation, levodopa, and stimulation responsiveness were analyzed. The distance of stimulation location from the subthalamic motor center was calculated individually in each plane of the three dimensions. We analyzed the sway values in the four stimulation conditions in the patient group and compared them with the control values. We explored factor combinations (with age as confounder) in the patient group predictive for imbalance with cluster analysis and a machine-learning-based multiple regression method.Sway combined from the four tasks did not differ in the patients and controls on a group level. The combination of the disease duration, the preoperative levodopa responsiveness, and the stimulation responsiveness predicted individual stimulation-induced static imbalance. The more affected patients had more severe motor symptoms; primarily, the proprioceptive followed by visual sensory feedback loss provoked imbalance in them when switching on the stimulation.The duration of the disease, the severity of motor symptoms, the levodopa responsiveness, and additional sensory deficits should be carefully considered during preoperative evaluation to predict subthalamic stimulation-induced imbalance in Parkinson's disease.}, year = {2022}, eissn = {1932-6203}, orcid-numbers = {Kelemen, Andrea Judit/0000-0002-7969-9197; Erőss, Loránd/0000-0002-5796-5546; Zádori, Dénes/0000-0003-0749-7980; Klivényi, Péter/0000-0002-5389-3266; Bereczki, Dániel/0000-0002-8374-0500; Tamás, Gertrúd/0000-0001-8054-3678} } @article{MTMT:32635795, title = {Joint involvement, disease activity and quality of life in pediatric Crohn's disease - a cross-sectional study}, url = {https://m2.mtmt.hu/api/publication/32635795}, author = {Dérfalvi, Beáta and Boros, Kriszta Katinka and Szabó, Dolóresz and Bozsaki, Gabor and Cseh, Áron and Rudas, Gábor and Müller, Katalin Eszter and Veres, Gábor}, doi = {10.1186/s12969-022-00664-z}, journal-iso = {PEDIATR RHEUMATOL}, journal = {PEDIATRIC RHEUMATOLOGY}, volume = {20}, unique-id = {32635795}, issn = {1546-0096}, abstract = {Few published data describe how joint involvement, the most prevalent extraintestinal manifestation, affects quality of life (QoL) of children with Crohn's disease (CD). Arthritis and arthralgia rates in pediatric CD patients are reportedly 3-24% and 17-22%, respectively, but studies on pre-emptive and systematic screening of joint involvement with detailed musculoskeletal rheumatological exam are lacking. More detailed data collection on joint involvement improves our understanding of how arthropathy relates to disease activity and QoL measured by the Pediatric CD Activity Index (PCDAI) and IMPACT-III questionnaire. Our study aims were to assess joint involvement in pediatric CD and correlate it with the PCDAI and IMPACT-III.In this cross-sectional, observational study, a pediatric gastroenterologist assessed consecutively-seen pediatric CD patients at a tertiary care center. Patients were screened for prevalence of current and previous arthropathy, including arthritis, enthesitis and arthralgia. A single experienced pediatric rheumatologist evaluated detailed musculoskeletal history, joint status, and modified Juvenile Arthritis Multidimensional Assessment Reports (JAMAR). PCDAI, IMPACT-III, sacroiliac MRI, and HLA-B27 genetic testing were also completed.A total of 82 (male:female, 1.2:1; age, 13.7 ± 3.2 years) patients were involved in this study. Mean disease duration at time of study was 21.6 ± 21 months; eight of the patients were newly-diagnosed. Of the 82 patients, 29 (35%) had evidence of arthritis; for 24 of those, this was revealed by physical exam during cross-sectional screening, and by prior documentation for the remaining five patients. Joint examination confirmed active arthritis in 8/24 (33%), active enthesitis in 1/24 (4%), and evidence of previous arthritis in 15/24 (62.5%) patients. Hip (41%) and knee (38%) joints were most commonly affected. Cumulative incidence of arthralgia was 48% (39/82), and 46% (18/39) of those patients had only arthralgia without arthritis, usually affecting the knee. Axial involvement was present in 10/82 (12%) patients. Joint involvement correlated with more severe CD disease activity, specifically higher PCDAI and lower IMPACT-III scores, and increased requirement for infliximab treatment. Sacroiliitis and HLA-B27 positivity were insignificant factors in this cohort.When a rheumatologist performed the assessment, joint involvement in pediatric CD was more prevalent than previously reported, in this cross-sectional study. Arthritis was associated with more severe CD disease activity and lower QoL.}, keywords = {ARTHRITIS; Quality of Life; arthralgia; JOINT INVOLVEMENT; pediatric Crohn's disease; Pediatric Crohn's disease activity index}, year = {2022}, eissn = {1546-0096}, orcid-numbers = {Dérfalvi, Beáta/0000-0001-9208-312X; Boros, Kriszta Katinka/0000-0002-7635-4628; Szabó, Dolóresz/0000-0001-5557-1861; Cseh, Áron/0000-0003-1659-3173; Müller, Katalin Eszter/0000-0001-5355-4224; Veres, Gábor/0000-0002-0911-1941} } @article{MTMT:32606943, title = {Regular Practice of Autogenic Training Reduces Migraine Frequency and Is Associated With Brain Activity Changes in Response to Fearful Visual Stimuli}, url = {https://m2.mtmt.hu/api/publication/32606943}, author = {Dobos, Dóra and Szabó, Edina and Baksa, Dániel and Gecse, Kinga and Kocsel, Natália and Pap, Dorottya and Zsombók, Terézia Ibolya and Kozák, Lajos Rudolf and Kökönyei, Gyöngyi and Juhász, Gabriella}, doi = {10.3389/fnbeh.2021.780081}, journal-iso = {FRONT BEHAV NEUROSCI}, journal = {FRONTIERS IN BEHAVIORAL NEUROSCIENCE}, volume = {15}, unique-id = {32606943}, year = {2022}, eissn = {1662-5153}, orcid-numbers = {Dobos, Dóra/0000-0002-2291-8854; Szabó, Edina/0000-0003-4087-5373; Baksa, Dániel/0000-0002-7826-9179; Gecse, Kinga/0000-0002-3512-2572; Kocsel, Natália/0000-0001-6892-796X; Zsombók, Terézia Ibolya/0000-0002-7535-0465; Kozák, Lajos Rudolf/0000-0003-0368-3663; Kökönyei, Gyöngyi/0000-0001-6750-2644; Juhász, Gabriella/0000-0002-5975-4267} } @article{MTMT:32594100, title = {Regular practice of autogenic training reduces migraine frequency and associated with brain activity changes in response to fearful visual stimuli.}, url = {https://m2.mtmt.hu/api/publication/32594100}, author = {Dobos, Dóra and Szabó, Edina and Baksa, Dániel and Gecse, Kinga and Kocsel, Natália and Pap, Dorottya and Zsombók, Terézia Ibolya and Kozák, Lajos Rudolf and Kökönyei, Gyöngyi and Juhász, Gabriella}, journal-iso = {J HEADACHE PAIN}, journal = {JOURNAL OF HEADACHE AND PAIN}, volume = {22}, unique-id = {32594100}, issn = {1129-2369}, year = {2021}, eissn = {1129-2377}, pages = {48-49}, orcid-numbers = {Dobos, Dóra/0000-0002-2291-8854; Szabó, Edina/0000-0003-4087-5373; Baksa, Dániel/0000-0002-7826-9179; Gecse, Kinga/0000-0002-3512-2572; Kocsel, Natália/0000-0001-6892-796X; Zsombók, Terézia Ibolya/0000-0002-7535-0465; Kozák, Lajos Rudolf/0000-0003-0368-3663; Kökönyei, Gyöngyi/0000-0001-6750-2644; Juhász, Gabriella/0000-0002-5975-4267} } @misc{MTMT:32592204, title = {Increased mPFC-ACC functional connectivity is associated with increased pain perception in migraine.}, url = {https://m2.mtmt.hu/api/publication/32592204}, author = {Kökönyei, Gyöngyi and Galambos, Attila and Gecse, Kinga and Dobos, Dóra and Aranyi, Sándor Csaba and Emri, Miklós and Kozák, Lajos Rudolf and Bagdy, György and Juhász, Gabriella}, unique-id = {32592204}, year = {2021}, orcid-numbers = {Kökönyei, Gyöngyi/0000-0001-6750-2644; Galambos, Attila/0000-0002-4587-9288; Gecse, Kinga/0000-0002-3512-2572; Dobos, Dóra/0000-0002-2291-8854; Aranyi, Sándor Csaba/0000-0001-9569-5404; Kozák, Lajos Rudolf/0000-0003-0368-3663; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267} } @article{MTMT:32554831, title = {Inter-individual differences in pain anticipation and pain perception in migraine: Neural correlates of migraine frequency and cortisol-to-dehydroepiandrosterone sulfate (DHEA-S) ratio}, url = {https://m2.mtmt.hu/api/publication/32554831}, author = {Kökönyei, Gyöngyi and Galambos, Attila and Kocsel, Natália and Szabó, Edina and Édes, Andrea Edit and Gecse, Kinga and Baksa, Dániel and Pap, Dorottya and Kozák, Lajos Rudolf and Bagdy, György and Juhász, Gabriella}, doi = {10.1371/journal.pone.0261570}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {16}, unique-id = {32554831}, issn = {1932-6203}, year = {2021}, eissn = {1932-6203}, orcid-numbers = {Kökönyei, Gyöngyi/0000-0001-6750-2644; Galambos, Attila/0000-0002-4587-9288; Kocsel, Natália/0000-0001-6892-796X; Szabó, Edina/0000-0003-4087-5373; Gecse, Kinga/0000-0002-3512-2572; Baksa, Dániel/0000-0002-7826-9179; Kozák, Lajos Rudolf/0000-0003-0368-3663; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267} } @article{MTMT:32062144, title = {New Insights of Phospholipase A2 Associated Neurodegeneration Phenotype Based on the Long-Term Follow-Up of a Large Hungarian Family}, url = {https://m2.mtmt.hu/api/publication/32062144}, author = {Tóth-Bencsik, Renáta and Balicza, Péter and Varga, Edina Tímea and Lengyel, Andras and Rudas, Gábor and Gál, Anikó and Molnár, Mária Judit}, doi = {10.3389/fgene.2021.628904}, journal-iso = {FRONT GENET}, journal = {FRONTIERS IN GENETICS}, volume = {12}, unique-id = {32062144}, year = {2021}, eissn = {1664-8021}, orcid-numbers = {Tóth-Bencsik, Renáta/0000-0003-0527-8979; Balicza, Péter/0000-0001-8555-5467; Varga, Edina Tímea/0000-0002-9365-3689; Gál, Anikó/0000-0002-2059-5748; Molnár, Mária Judit/0000-0001-9350-1864} }