TY - JOUR AU - Máthé, Csaba AU - Bóka, Károly AU - Kónya, Zoltán AU - Erdődi, Ferenc AU - Vasas, Gábor AU - Freytag, Csongor AU - Garda, Tamás TI - Microcystin-LR, a cyanotoxin, modulates division of higher plant chloroplasts through protein phosphatase inhibition and affects cyanobacterial division JF - CHEMOSPHERE J2 - CHEMOSPHERE VL - 358 PY - 2024 PG - 11 SN - 0045-6535 DO - 10.1016/j.chemosphere.2024.142125 UR - https://m2.mtmt.hu/api/publication/34836717 ID - 34836717 LA - English DB - MTMT ER - TY - JOUR AU - Prati, Sebastian AU - Grabner, Daniel S. AU - Hupało, Kamil AU - Weiperth, András AU - Maciaszek, Rafał AU - Lipták, Boris AU - Bojko, Jamie AU - Bérces, Fanni AU - Sures, Bernd TI - Invisible invaders: range expansion of feral Neocaridina davidi offers new opportunities for generalist intracellular parasites JF - BIOLOGICAL INVASIONS J2 - BIOL INVASIONS VL - 1 PY - 2024 SP - 1 EP - 26 PG - 26 SN - 1387-3547 DO - 10.1007/s10530-024-03324-3 UR - https://m2.mtmt.hu/api/publication/34834630 ID - 34834630 AB - The release of ornamental pets and associated pathogens outside their native range might directly or indirectly impact the recipient community. In temperate regions, e.g., central Europe, feral freshwater species of tropical and sub-tropical origins are mainly constrained to thermally polluted waters and thermal springs. However, species with high environmental plasticity and reproduction rates, such as the shrimp Neocaridina davidi , may adapt to colder water regimes over time. A widening thermal niche may eventually overcome thermal barriers, further expanding the range and enhancing transmission opportunities for host generalist parasites. This study assesses the observed (field observations) and theoretical (species distribution models) range expansion of N. davidi and associated parasites in Europe. We report three newly established N. davidi populations from thermally polluted waters in central Europe (Germany, Hungary, and Slovakia) and provide further evidence of its range expansion into colder environments. Species distribution models predict thermally suitable habitats in the Mediterranean and a foreseeable expansion into Western Europe and the Balkans by 2050. We confirm the presence of the microsporidian parasite Ecytonucleospora hepatopenaei in feral N. davidi populations across Europe and expand the list of microsporidians found in this host from two to four. Furthermore, we provide the first evidence of parasite spillover from/to the invasive crayfish Procambarus clarkii, suggesting that parasite exchange with native biota might be possible. Such possibility, coupled with an ongoing range expansion of N. davidi bolstered by human-mediated introductions and climate change, will likely exacerbate the impact on native biota. LA - English DB - MTMT ER - TY - JOUR AU - Reicher, Vivien AU - Kovács, Tímea AU - Csibra, Barbara AU - Gácsi, Márta TI - Potential interactive effect of positive expectancy violation and sleep on memory consolidation in dogs JF - SCIENTIFIC REPORTS J2 - SCI REP VL - 14 PY - 2024 IS - 1 SN - 2045-2322 DO - 10.1038/s41598-024-60166-8 UR - https://m2.mtmt.hu/api/publication/34831542 ID - 34831542 N1 - Export Date: 2 May 2024 Correspondence Address: Reicher, V.; Clinical and Developmental Neuropsychology Research Group, Hungary; email: reicher.vivien@ttk.hu AB - In dogs, as in humans, both emotional and learning pretreatment affect subsequent behaviour and sleep. Although learning often occurs in an emotional-social context, the emotion-learning interplay in such context remain mainly unknown. Aims were to assess the effects of Controlling versus Permissive (emotional factors) training (learning factors) styles on dogs’ behaviour, learning performance, and sleep. Family dogs ( N = 24) participated in two command learning sessions employing the two training styles with each session followed by assessment of learning performance, a 2-h-long non-invasive sleep EEG measurement, and a retest of learning performance. Pre- to post-sleep improvement in learning performance was evident in dogs that received the Permissive training during the second learning session, indicating that dogs that experienced a more rewarding situation than expected (positive expectancy violation) during the second training session showed improved learning success after their afternoon sleep. These results possibly indicate an interactive effect of expectancy violation and sleep on enhancing learning. LA - English DB - MTMT ER - TY - JOUR AU - Puska, Gina AU - Szendi, Vivien AU - Dobolyi, Árpád TI - Lateral septum as a possible regulatory center of maternal behaviors JF - NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS J2 - NEUROSCI BIOBEHAV R VL - 161 PY - 2024 PG - 11 SN - 0149-7634 DO - 10.1016/j.neubiorev.2024.105683 UR - https://m2.mtmt.hu/api/publication/34828140 ID - 34828140 LA - English DB - MTMT ER - TY - JOUR AU - Abbaszade, Gorkhmaz AU - Toumi, Marwene AU - Farkas, Rózsa AU - Vajna, Balázs AU - Krett, Gergely AU - Dobosy, Péter AU - Szabó, Csaba AU - M Tóth, Erika TI - Corrigendum to “Exploring the relationship between metal(loid) contamination rate, physicochemical conditions, and microbial community dynamics in industrially contaminated urban soils” [Sci. Total Environ. 897 (2023) 166094] JF - SCIENCE OF THE TOTAL ENVIRONMENT J2 - SCI TOTAL ENVIRON VL - 928 PY - 2024 SN - 0048-9697 DO - 10.1016/j.scitotenv.2024.172532 UR - https://m2.mtmt.hu/api/publication/34826724 ID - 34826724 LA - English DB - MTMT ER - TY - JOUR AU - Chaves, Tiago AU - Török, Bibiána AU - Fazekas, Csilla Lea AU - Correia, Pedro AU - Bodóné Sipos, Eszter AU - Várkonyi, Dorottya AU - Tóth, Zsuzsanna AU - Dóra, Fanni AU - Dobolyi, Árpád AU - Zelena, Dóra TI - The Dopaminergic Cells in the Median Raphe Region Regulate Social Behavior in Male Mice. JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 8 PG - 22 SN - 1661-6596 DO - 10.3390/ijms25084315 UR - https://m2.mtmt.hu/api/publication/34825010 ID - 34825010 AB - According to previous studies, the median raphe region (MRR) is known to contribute significantly to social behavior. Besides serotonin, there have also been reports of a small population of dopaminergic neurons in this region. Dopamine is linked to reward and locomotion, but very little is known about its role in the MRR. To address that, we first confirmed the presence of dopaminergic cells in the MRR of mice (immunohistochemistry, RT-PCR), and then also in humans (RT-PCR) using healthy donor samples to prove translational relevance. Next, we used chemogenetic technology in mice containing the Cre enzyme under the promoter of the dopamine transporter. With the help of an adeno-associated virus, designer receptors exclusively activated by designer drugs (DREADDs) were expressed in the dopaminergic cells of the MRR to manipulate their activity. Four weeks later, we performed an extensive behavioral characterization 30 min after the injection of the artificial ligand (Clozapine-N-Oxide). Stimulation of the dopaminergic cells in the MRR decreased social interest without influencing aggression and with an increase in social discrimination. Additionally, inhibition of the same cells increased the friendly social behavior during social interaction test. No behavioral changes were detected in anxiety, memory or locomotion. All in all, dopaminergic cells were present in both the mouse and human samples from the MRR, and the manipulation of the dopaminergic neurons in the MRR elicited a specific social response. LA - English DB - MTMT ER - TY - JOUR AU - Gnecchi-Ruscone, Guido Alberto AU - Rácz, Zsófia AU - Samu, Levente AU - Szeniczey, Tamás AU - Faragó, Norbert AU - Knipper, Corina AU - Friedrich, Ronny AU - Zlámalová, Denisa AU - Traverso, Luca AU - Liccardo, Salvatore AU - Wabnitz, Sandra AU - Popli, Divyaratan AU - Wang, Ke AU - Radzeviciute, Rita AU - Gulyás, Bence AU - Koncz, István AU - Balogh, Csilla AU - Lezsák, Gabriella M. AU - Mácsai, Viktor AU - Bunbury, Magdalena M. E. AU - Spekker, Olga AU - le Roux, Petrus AU - Szécsényi-Nagy, Anna AU - Mende, Balázs Gusztáv AU - Colleran, Heidi AU - Hajdu, Tamás AU - Geary, Patrick AU - Pohl, Walter AU - Vida, Tivadar AU - Krause, Johannes AU - Hofmanová, Zuzana TI - Network of large pedigrees reveals social practices of Avar communities JF - NATURE J2 - NATURE PY - 2024 PG - 25 SN - 0028-0836 DO - 10.1038/s41586-024-07312-4 UR - https://m2.mtmt.hu/api/publication/34822257 ID - 34822257 AB - From ad 567–568, at the onset of the Avar period, populations from the Eurasian Steppe settled in the Carpathian Basin for approximately 250 years 1 . Extensive sampling for archaeogenomics (424 individuals) and isotopes, combined with archaeological, anthropological and historical contextualization of four Avar-period cemeteries, allowed for a detailed description of the genomic structure of these communities and their kinship and social practices. We present a set of large pedigrees, reconstructed using ancient DNA, spanning nine generations and comprising around 300 individuals. We uncover a strict patrilineal kinship system, in which patrilocality and female exogamy were the norm and multiple reproductive partnering and levirate unions were common. The absence of consanguinity indicates that this society maintained a detailed memory of ancestry over generations. These kinship practices correspond with previous evidence from historical sources and anthropological research on Eurasian Steppe societies 2 . Network analyses of identity-by-descent DNA connections suggest that social cohesion between communities was maintained via female exogamy. Finally, despite the absence of major ancestry shifts, the level of resolution of our analyses allowed us to detect genetic discontinuity caused by the replacement of a community at one of the sites. This was paralleled with changes in the archaeological record and was probably a result of local political realignment. LA - English DB - MTMT ER - TY - JOUR AU - Krenhardt, Katalin AU - Martínez-Padilla, Jesús AU - Canal, David AU - Jablonszky, Mónika AU - Hegyi, Gergely AU - Herényi, Márton AU - Laczi, Miklós AU - Markó, Gábor AU - Nagy, Gergely AU - Rosivall, Balázs AU - Szász, Eszter AU - Szöllősi, Eszter AU - Török, János AU - Vaskuti, Éva AU - Zsebők, Sándor AU - Garamszegi, László Zsolt TI - The effect of environmental variation on the relationship between survival and risk-taking behaviour in a migratory songbird JF - JOURNAL OF EVOLUTIONARY BIOLOGY J2 - J EVOLUTION BIOL PY - 2024 SN - 1010-061X DO - 10.1093/jeb/voae046 UR - https://m2.mtmt.hu/api/publication/34820583 ID - 34820583 AB - Temporal changes in environmental conditions may play a major role in the year-to-year variation in fitness consequences of behaviours. Identifying environmental drivers of such variation is crucial to understand the evolutionary trajectories of behaviours in natural contexts. However, our understanding of how environmental variation influences behaviours in the wild remains limited. Using data collected over 14 breeding seasons from a collared flycatcher (Ficedula albicollis) population, we examined the effect of environmental variation on the relationship between survival and risk-taking behaviour, a highly variable behavioural trait with great evolutionary and ecological significance. Specifically, using annual recapture probability as a proxy of survival, we evaluated the specific effect of predation pressure, food availability and mean temperature on the relationship between annual recapture probability and risk-taking behaviour (measured as flight initiation distance, FID). We found a negative trend, as the relationship between annual recapture probability and FID decreased over the study years, and changed from positive to negative. Specifically, in the early years of the study, risk-avoiding individuals exhibited a higher annual recapture probability, whereas in the later years, risk-avoiders had a lower annual recapture probability. However, we did not find evidence that any of the considered environmental factors mediated the variation in the relationship between survival and risk-taking behaviour. LA - English DB - MTMT ER - TY - JOUR AU - el Battioui, Kamal AU - Chakraborty, Sohini AU - Wacha, András AU - Molnár, Dániel AU - Quemé-Peña, Mayra AU - Szigyártó, Imola Cs. AU - Szabó, Csenge Lilla AU - Bodor, Andrea AU - Horváti, Kata AU - Gyulai, Gergő AU - Bősze, Szilvia AU - Mihály, Judith AU - Jezsó, Bálint AU - Románszki, Loránd AU - Tóth, Judit AU - Varga, Zoltán AU - Mándity, István AU - Juhász, Tünde AU - Beke-Somfai, Tamás TI - In situ captured antibacterial action of membrane-incising peptide lamellae JF - NATURE COMMUNICATIONS J2 - NAT COMMUN VL - 15 PY - 2024 IS - 1 PG - 14 SN - 2041-1723 DO - 10.1038/s41467-024-47708-4 UR - https://m2.mtmt.hu/api/publication/34819821 ID - 34819821 AB - Developing unique mechanisms of action are essential to combat the growing issue of antimicrobial resistance. Supramolecular assemblies combining the improved biostability of non-natural compounds with the complex membrane-attacking mechanisms of natural peptides are promising alternatives to conventional antibiotics. However, for such compounds the direct visual insight on antibacterial action is still lacking. Here we employ a design strategy focusing on an inducible assembly mechanism and utilized electron microscopy (EM) to follow the formation of supramolecular structures of lysine-rich heterochiral β 3 -peptides, termed lamellin-2K and lamellin-3K, triggered by bacterial cell surface lipopolysaccharides. Combined molecular dynamics simulations, EM and bacterial assays confirmed that the phosphate-induced conformational change on these lamellins led to the formation of striped lamellae capable of incising the cell envelope of Gram-negative bacteria thereby exerting antibacterial activity. Our findings also provide a mechanistic link for membrane-targeting agents depicting the antibiotic mechanism derived from the in-situ formation of active supramolecules. LA - English DB - MTMT ER - TY - JOUR AU - Blanvillain, Gaëlle AU - Lorch, Jeffrey M. AU - Joudrier, Nicolas AU - Bury, Stanislaw AU - Cuenot, Thibault AU - Franzen, Michael AU - Martínez-Freiría, Fernando AU - Guiller, Gaëtan AU - Halpern, Bálint AU - Kolanek, Aleksandra AU - Kurek, Katarzyna AU - Lourdais, Olivier AU - Michon, Alix AU - Musilová, Radka AU - Schweiger, Silke AU - Szulc, Barbara AU - Ursenbacher, Sylvain AU - Zinenko, Oleksandr AU - Hoyt, Joseph R. TI - Contribution of host species and pathogen clade to snake fungal disease hotspots in Europe JF - COMMUNICATIONS BIOLOGY J2 - COMMUN BIOL VL - 7 PY - 2024 IS - 1 SN - 2399-3642 DO - 10.1038/s42003-024-06092-x UR - https://m2.mtmt.hu/api/publication/34816315 ID - 34816315 AB - Infectious diseases are influenced by interactions between host and pathogen, and the number of infected hosts is rarely homogenous across the landscape. Areas with elevated pathogen prevalence can maintain a high force of infection and may indicate areas with disease impacts on host populations. However, isolating the ecological processes that result in increases in infection prevalence and intensity remains a challenge. Here we elucidate the contribution of pathogen clade and host species in disease hotspots caused by Ophidiomyces ophidiicola , the pathogen responsible for snake fungal disease, in 21 species of snakes infected with multiple pathogen strains across 10 countries in Europe. We found isolated areas of disease hotspots in a landscape where infections were otherwise low. O. ophidiicola clade had important effects on transmission, and areas with multiple pathogen clades had higher host infection prevalence. Snake species further influenced infection, with most positive detections coming from species within the Natrix genus. Our results suggest that both host and pathogen identity are essential components contributing to increased pathogen prevalence. LA - English DB - MTMT ER -