TY - CONF AU - Gube, Addisu Alemayehu AU - Murányi, Edit AU - Vitrai, József AU - Lohner, Szimonetta ED - Kovács, Bettina ED - Glázer-Kniesz, Adrienn ED - Tislér, Ádám TI - Inequity in uptake of maternal health care services in developing countries: a systematic review and meta-analysis T2 - Absztraktkötet: XII. Interdiszciplináris Doktorandusz Konferencia = Book of Abstract: XII. Interdisciplinary Doctoral Conference PB - Pécsi Tudományegyetem Doktorandusz Önkormányzat C1 - Pécs SN - 9789636262457 PY - 2024 SP - 27 EP - 27 PG - 1 UR - https://m2.mtmt.hu/api/publication/34813318 ID - 34813318 LA - English DB - MTMT ER - TY - CHAP AU - Maróti, Péter AU - Kiss, István ED - Vámos, Zoltán TI - A baleseti agysérülés epidemiológiája T2 - Súlyos baleseti agysérültek ellátása PB - Medicina Könyvkiadó CY - Budapest SN - 9789632269177 PY - 2024 SP - 9789632269177 UR - https://m2.mtmt.hu/api/publication/34794735 ID - 34794735 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Macharia, John Macharia AU - O. Pande, Daniel AU - Zand, Afshin AU - Budán, Ferenc Csaba AU - Káposztás, Zsolt AU - Kövesdi, Orsolya Liza AU - Varjas, Tímea AU - Raposa, Bence TI - In Vitro Inhibition of Colorectal Cancer Gene Targets by Withania somnifera L. Methanolic Extracts: A Focus on Specific Genome Regulation JF - NUTRIENTS J2 - NUTRIENTS VL - 16 PY - 2024 IS - 8 PG - 13 SN - 2072-6643 DO - 10.3390/nu16081140 UR - https://m2.mtmt.hu/api/publication/34788027 ID - 34788027 N1 - Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary Department of Biological Sciences and Biomedical Science & Technology, School of Science and Applied Technology, Laikipia University, Nyahururu P.O. Box 1100-20300, Kenya Department of Public Health Medicine, Medical School, University of Pécs, 7621 Pécs, Hungary Institute of Physiology, Medical School, University of Pécs, 7621 Pécs, Hungary Faculty of Health Sciences, University of Pécs, 7621 Pécs, Hungary Institute of Basics of Health Sciences, Midwifery and Health Visiting, Faculty of Health Sciences, University of Pécs, Vörösmarty Mihály Str. 4, 7621 Pécs, Hungary Export Date: 6 May 2024 LA - English DB - MTMT ER - TY - JOUR AU - Patrick Nyamemba, Nyakundi AU - Kiio, Juliana AU - Munyaka, Ann Wambui AU - Galgalo, Dahabo AU - Lohner, Szimonetta TI - Consumption Pattern of Tea Is Associated with Serum Ferritin Levels of Women of Childbearing Age in Nandi County, Kenya : A Cross-Sectional Study JF - ANNALS OF NUTRITION AND METABOLISM J2 - ANN NUTR METAB VL - 80 PY - 2024 IS - 2 SP - 109 EP - 116 PG - 8 SN - 0250-6807 DO - 10.1159/000536196 UR - https://m2.mtmt.hu/api/publication/34786852 ID - 34786852 N1 - Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Pecs, Hungary Department of Food, Nutrition and Dietetics, Kenyatta University, Nairobi, Kenya Department of Hospitality and Institutional Management, Nkabune Technical Training Institute, Meru, Kenya Department of Public Health Medicine, Medical School, University of Pécs, Pecs, Hungary Department of Public Health, Marsabit County Ministry of Health, Marsabit, Kenya Cochrane Hungary, Clinical Center of the University of Pécs, Medical School, University of Pécs, Pecs, Hungary Export Date: 22 April 2024 CODEN: ANUMD Correspondence Address: Nyakundi, P.N.; Doctoral School of Health Sciences, Hungary; email: info.nyamemba@gmail.com AB - Tea consumption with meals affects iron absorption, increasing the risk of iron deficiency. Our study investigated the association between tea consumption patterns and serum ferritin levels among women of childbearing age (WCA) in Nandi County, Kenya.We conducted a cross-sectional analytical study among 160 WCA selected using a systematic random sampling technique from Kapsabet Ward. Information on tea consumption practices was gathered using a researcher-administered questionnaire, and serum ferritin and C-reactive protein were measured. We assessed associations between tea consumption and iron status of respondents by multivariable regression analysis, adjusting for potential confounders, including parasitic infections and recent severe blood losses.The prevalence of anaemia and iron deficiency among the study participants were 86.2% and 45%, respectively. Majority (90.6%) of the respondents consumed tea or coffee, with an infusion time of more than 5 min (60.0%) and a moderate tea strength (64.1%), within 1 h before or after meals. Iron deficiency was associated the number of teacups consumed (adjusted odds ratio = 7.282, 95% CI = 3.580-14.812).High tea consumption is positively associated with iron deficiency among WCA. Lower tea infusion strength, shorter tea infusion duration, and a lower number of teacups overall consumed, as well as consuming tea 1 h before or after meals instead of with meals, may be recommended for better outcomes in iron status among WCA. LA - English DB - MTMT ER - TY - JOUR AU - Schandelmaier, Stefan AU - Guyatt, Gordon TI - Same Old Challenges in Subgroup Analysis-Should We Do More About Methods Implementation? JF - JAMA NETWORK OPEN J2 - JAMA NETW OPEN VL - 7 PY - 2024 IS - 3 PG - 3 SN - 2574-3805 DO - 10.1001/jamanetworkopen.2024.3339 UR - https://m2.mtmt.hu/api/publication/34763929 ID - 34763929 N1 - Export Date: 18 April 2024 LA - English DB - MTMT ER - TY - JOUR AU - Bérczi, Bálint AU - Borbásné Farkas, Kornélia AU - Hegyi, Péter AU - Tóth, Barbara AU - Csupor, Dezső AU - Németh, Balázs AU - Lukács, Anita AU - Czumbel, László Márk AU - Kerémi, Beáta AU - Kiss, István AU - Szabó, Andrea AU - Varga, Gábor AU - Gerber, Gábor AU - Gyöngyi, Zoltán TI - Aromatase Inhibitors and Plasma Lipid Changes in Postmenopausal Women with Breast Cancer: A Systematic Review and Meta-Analysis JF - JOURNAL OF CLINICAL MEDICINE J2 - J CLIN MED VL - 13 PY - 2024 IS - 6 PG - 20 SN - 2077-0383 DO - 10.3390/jcm13061818 UR - https://m2.mtmt.hu/api/publication/34760472 ID - 34760472 N1 - Journal Article; Review AB - Background: Women are typically diagnosed with estrogen receptor-positive breast cancer around the postmenopausal period when declining estrogen levels initiate changes in lipid profiles. Aromatase inhibitors (AI) are used to prevent the progression of cancer; however, a further reduction in estrogen levels may have detrimental effects on lipid levels, which was our working hypothesis. Methods: Our meta-analysis was conducted on the lipid profiles of postmenopausal breast cancer patients at baseline and at different treatment time points. Results: We identified 15 studies, including 1708 patients. Studies using anastrozole (ANA), exemestane (EXE), letrozole (LET), and tamoxifen (TMX) were involved. Subgroup analyses revealed that 3- and 12-month administrations of LET and EXE lead to negative changes in lipid profiles that tend to alter the lipid profile undesirably, unlike ANA and TMX. Conclusions: Our results suggest that, despite statistically significant results, EXE and LET may not be sufficient to cause severe dyslipidemia in patients without cardiovascular comorbidities according to the AHA/ACC Guideline on the Management of Blood Cholesterol. However, the results may raise the question of monitoring the effects of AIs in patients, especially those with pre-existing cardiovascular risk factors such as dyslipidemia. LA - English DB - MTMT ER - TY - JOUR AU - Hirt, Julian AU - Ewald, Hannah AU - Briel, Matthias AU - Schandelmaier, Stefan TI - Searching a methods topic: practical challenges and implications for search design JF - JOURNAL OF CLINICAL EPIDEMIOLOGY J2 - J CLIN EPIDEMIOL VL - 166 PY - 2024 PG - 7 SN - 0895-4356 DO - 10.1016/j.jclinepi.2023.10.017 UR - https://m2.mtmt.hu/api/publication/34743842 ID - 34743842 N1 - Note LA - English DB - MTMT ER - TY - JOUR AU - Zand, Afshin AU - Sodbuyan, Enkhbilguun AU - Macharia, John Macharia AU - Varajti, Krisztina AU - Szabó, István AU - Gerencsér, Gellért AU - Tisza, Boglárka Bernadett AU - Raposa, Bence AU - Gyöngyi, Zoltán AU - Varjas, Tímea TI - Betanin Attenuates Epigenetic Mechanisms and UV-Induced DNA Fragmentation in HaCaT Cells: Implications for Skin Cancer Chemoprevention JF - NUTRIENTS J2 - NUTRIENTS VL - 16 PY - 2024 IS - 6 PG - 15 SN - 2072-6643 DO - 10.3390/nu16060860 UR - https://m2.mtmt.hu/api/publication/34741555 ID - 34741555 N1 - Funding Agency and Grant Number: University of Pecs, Medical School Funding text: No Statement Available LA - English DB - MTMT ER - TY - JOUR AU - Kang, Sunjoo AU - Rákosy, Zsuzsa AU - Park, Se Eun AU - Nguyen, Thi Anh Phuong TI - Editorial : Women in science: public health education and promotion 2023 JF - FRONTIERS IN PUBLIC HEALTH J2 - FRONT PUBLIC HEALTH VL - 12 PY - 2024 PG - 3 SN - 2296-2565 DO - 10.3389/fpubh.2024.1368704 UR - https://m2.mtmt.hu/api/publication/34725861 ID - 34725861 N1 - Editorial LA - English DB - MTMT ER - TY - JOUR AU - Bérczi, Bálint AU - Nusser, Nóra AU - Péter, Iván AU - Németh, Balázs AU - Gyöngyi, Zoltán TI - Association Between AIRE Polymorphisms rs870881(C>T), rs1003854(T>C) and Rheumatoid Arthritis Risk : A Hungarian Case-control Study JF - IN VIVO J2 - IN VIVO VL - 38 PY - 2024 IS - 2 SP - 774 EP - 784 PG - 11 SN - 0258-851X DO - 10.21873/invivo.13501 UR - https://m2.mtmt.hu/api/publication/34725857 ID - 34725857 N1 - Department of Public Health Medicine, Medical School, University of Pécs, Pécs, Hungary Harkány Thermal Rehabilitation Centre, Harkány, Hungary Export Date: 18 March 2024 CODEN: IVIVE Correspondence Address: Nemeth, B.; Department of Public Health Medicine, Szigeti str. 12, Hungary; email: balazs.nemeth@aok.pte.hu AB - Autoimmune regulator (AIRE) is a transcription factor that plays pivotal role in controlling autoimmunity. In the thymus, it supports the presentation of peripheral tissue antigens to developing T cells, where recognition of these self-antigens negatively selects the autoimmune naïve T-cells by central tolerance. Studies demonstrated that single-nucleotide polymorphisms (SNPs) in AIRE alter transcription and propagate clonal survival of autoimmune T cells, therefore increase susceptibility to autoimmune diseases. This study intended to identify SNPs in exon and intron sequences that determine AIRE transcription, where their genotypes are associated with rheumatoid arthritis (RA) risk and clinical parameters.After a thorough in silico research, we enrolled 100 patients with RA and 100 healthy controls to analyze the association of SNP rs870881(C>T) and rs1003854(T>C) in AIRE coding sequence with RA risk by using five different genetic models and selected clinical parameters. Multiplex quantitative polymerase chain reaction was used to determine allelic discrimination of SNPs. RA risk was assessed by odds ratios (ORs) and confidence intervals (CIs).In a recessive model of rs878081, minor allele TT homozygotes were associated with RA (p=0.032, OR=5.44, 95%CI=1.16-25.52); in a recessive model of rs1003854, minor allele CC homozygotes were associated with RA (p=0.047, OR=4.84, 95%CI=1.02-23.02). Higher C-reactive protein (CRP) levels in patients with RA were significantly associated with minor allele homozygotes in recessive and codominant genetic models (p=0.029 and p=0.043, respectively) of rs1003854.Genotypes for minor alleles of rs878081 and rs1003854 might be involved in RA pathogenesis and risk prediction. LA - English DB - MTMT ER -