TY - JOUR AU - Tóth, Kinga AU - Damjanova, I. AU - Laczkó, Levente AU - Buzgó, L. AU - Lesinszki, V. AU - Ungvári, E. AU - Jánvári, L. AU - Hanczvikkel, A. AU - Tóth, Á. AU - Szabó, Dóra TI - Genomic Epidemiology of C2/H30Rx and C1-M27 Subclades of Escherichia coli ST131 Isolates from Clinical Blood Samples in Hungary JF - ANTIBIOTICS J2 - ANTIBIOTICS-BASEL VL - 13 PY - 2024 IS - 4 PG - 18 SN - 2079-6382 DO - 10.3390/antibiotics13040363 UR - https://m2.mtmt.hu/api/publication/34838258 ID - 34838258 N1 - Institute of Medical Microbiology, Faculty of Medicine, Semmelweis University, Budapest, 1089, Hungary Department of Bacteriology, Parasitology and Mycology, National Center for Public Health and Pharmacy, Budapest, 1097, Hungary One Health Institute, Faculty of Health Sciences, University of Debrecen, Debrecen, 4032, Hungary HUN-REN-DE Conservation Biology Research Group, University of Debrecen, Debrecen, 4032, Hungary HUN-REN-SE Human Microbiota Research Group, Budapest, 1052, Hungary Neurosurgical and Neurointervention Clinic, Semmelweis University, Budapest, 1083, Hungary Export Date: 8 May 2024 Correspondence Address: Tóth, K.; Institute of Medical Microbiology, Hungary; email: toth.kinga@phd.semmelweis.hu LA - English DB - MTMT ER - TY - JOUR AU - Jones, S. AU - Juhász, Alexandra Csilla AU - Makaula, P. AU - Cunningham, L. J. AU - Archer, J. AU - Nkolokosa, C. AU - Namacha, G. AU - Kambewa, E. AU - Lally, D. AU - Kapira, D. R. AU - Chammudzi, P. AU - Kayuni, S. A. AU - Musaya, J. AU - Stothard, J. Russell TI - A first report of Pseudosuccinea columella (Say, 1817), an alien intermediate host for liver fluke, in Malawi JF - PARASITES AND VECTORS J2 - PARASITE VECT VL - 17 PY - 2024 IS - 1 PG - 5 SN - 1756-3305 DO - 10.1186/s13071-024-06241-5 UR - https://m2.mtmt.hu/api/publication/34833210 ID - 34833210 AB - Starting in October 2021, quarterly malacological surveys have been undertaken in Malawi, with the sampling of 12 specified freshwater habitats throughout a calendar year. Each survey monitors the presence of aquatic intermediate snail hosts of medical and veterinary importance. In March 2023, the alien lymnaeid species Pseudosuccinea columella was encountered for the first time in the surveys, in Nsanje District. This species identity was later confirmed upon DNA analysis of mitochondrial ribosomal 16S sequences. In July 2023, P. columella was also noted at single sites within Mangochi and Chikwawa Districts, and again in Nsanje District, with an additional location observed. Of particular importance, our sampled location in Mangochi District was directly connected to Lake Malawi, which expands the species list of invasive molluscs in this lake. While P. columella is a well-known intermediate snail host for human and animal fascioliasis, screening collected snails for trematode cercariae, alongside molecular xenomonitoring, did not yield equivocal evidence of active fluke infection. However, the newly recognized presence of this alien intermediate snail host within Lake Malawi, and along the Shire River Valley, flags a new concern in altered local transmission potential for human and animal fascioliasis. LA - English DB - MTMT ER - TY - JOUR AU - Monyók, Ádám AU - Mansour, Bassel AU - Vadnay, István AU - Makra, Nóra AU - Dunai, Zsuzsanna A. AU - Nemes-Nikodém, Éva AU - Stercz, Balázs AU - Szabó, Dóra AU - Ostorházi, Eszter TI - Change in Tissue Microbiome and Related Human Beta Defensin Levels Induced by Antibiotic Use in Bladder Carcinoma JF - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES J2 - INT J MOL SCI VL - 25 PY - 2024 IS - 8 PG - 16 SN - 1661-6596 DO - 10.3390/ijms25084562 UR - https://m2.mtmt.hu/api/publication/34824221 ID - 34824221 AB - It is now generally accepted that the success of antitumor therapy can be impaired by concurrent antibiotic therapy, the presence of certain bacteria, and elevated defensin levels around the tumor tissue. The aim of our current investigation was to identify the underlying changes in microbiome and defensin levels in the tumor tissue induced by different antibiotics, as well as the duration of this modification. The microbiome of the tumor tissues was significantly different from that of healthy volunteers. Comparing only the tumor samples, no significant difference was confirmed between the untreated group and the group treated with antibiotics more than 3 months earlier. However, antibiotic treatment within 3 months of analysis resulted in a significantly modified microbiome composition. Irrespective of whether Fosfomycin, Fluoroquinolone or Beta-lactam treatment was used, the abundance of Bacteroides decreased, and Staphylococcus abundance increased. Large amounts of the genus Acinetobacter were observed in the Fluoroquinolone-treated group. Regardless of the antibiotic treatment, hBD1 expression of the tumor cells consistently doubled. The increase in hBD2 and hBD3 expression was the highest in the Beta-lactam treated group. Apparently, antibiotic treatment within 3 months of sample analysis induced microbiome changes and defensin expression levels, depending on the identity of the applied antibiotic. LA - English DB - MTMT ER - TY - JOUR AU - Archer, J. AU - Yeo, S.M. AU - Gadd, G. AU - Pennance, T. AU - Cunningham, L.J. AU - Juhász, Alexandra Csilla AU - Jones, S. AU - Chammudzi, P. AU - Kapira, D.R. AU - Lally, D. AU - Namacha, G. AU - Mainga, B. AU - Makaula, P. AU - LaCourse, J.E. AU - Kayuni, S.A. AU - Musaya, J. AU - Stothard, J.R. AU - Webster, B.L. TI - Development, validation, and pilot application of a high throughput molecular xenomonitoring assay to detect Schistosoma mansoni and other trematode species within Biomphalaria freshwater snail hosts JF - CURRENT RESEARCH IN PARASITOLOGY & VECTOR-BORNE DISEASES J2 - Current Research in Parasitology & Vector-Borne Diseases VL - 5 PY - 2024 PG - 9 SN - 2667-114X DO - 10.1016/j.crpvbd.2024.100174 UR - https://m2.mtmt.hu/api/publication/34795482 ID - 34795482 LA - English DB - MTMT ER - TY - JOUR AU - Huber, Annamária AU - Kovács, Eszter AU - Horváth, Andrea AU - Sahin-Tóth, Judit AU - Kaptás, Ákos AU - Juhász, Emese AU - Kristóf, Katalin AU - Dobay, Orsolya TI - Prevalence, serogroup distribution and risk factors of Neisseria meningitidis carriage in high school and university students in Hungary JF - VACCINE J2 - VACCINE VL - 42 PY - 2024 IS - 9 SP - 2271 EP - 2277 PG - 7 SN - 0264-410X DO - 10.1016/j.vaccine.2024.02.064 UR - https://m2.mtmt.hu/api/publication/34770075 ID - 34770075 LA - English DB - MTMT ER - TY - JOUR AU - Farkas, Csaba AU - Juhász, Alexandra Csilla AU - Fekete, Balázs AU - Egri, Borisz TI - Comparative Analysis of Ascaris suum and Macracanthorhynchus hirudinaceus Infections in Free-Ranging and Captive Wild Boars (Sus scrofa) in Hungary JF - ANIMALS J2 - ANIMALS-BASEL VL - 14 PY - 2024 IS - 6 PG - 14 SN - 2076-2615 DO - 10.3390/ani14060932 UR - https://m2.mtmt.hu/api/publication/34767269 ID - 34767269 AB - Ascaris suum and Macracanthorhynchus hirudinaceus cause a large loss of yield in farm animals as well as in free-living and captive wild boar herds, thereby causing economic damage. This study compared A. suum and M. hirudinaceus infections in free-ranging and captive wild boars (Sus scrofa) in Hungary. The authors measured the A. suum and M. hirudinaceus infections of a 248-hectare wild boar garden and an 11,893-hectare free-living wild boar herd in the sample area. In all cases, samples were collected from shot wild boars. In total, 216 wild boars were examined from June 2015 to June 2023 in Hungary. Of the 173 dissected wild boars from the wild, 57 (32.9%) were infected with A. suum, while 30 (69.8%) of the 43 individuals from the captive area were infected. The prevalence of M. hirudinaceus in the free-living area population was 9.25% (16 wild boars), while that of the captive population was 34.89% (15 wild boars). In the case of the examined helminths, the captive herd was 36.9% more infected than the herd living in the open area. LA - English DB - MTMT ER - TY - JOUR AU - Vasilakopoulou, A. AU - Naas, T. AU - Gonzalez, C. AU - Vila, J. AU - Szabó, Dóra AU - Riccobono, E. AU - Kamotsay, K. AU - Reissier, S. AU - Berbel, D. AU - Aszalós, Zoltán AU - Rosenmoller, M. AU - Stankov-Puges, M. AU - Georgiou, P.-C. AU - Vourli, S. AU - Volland, H. AU - Pournaras, S. TI - A multicentre evaluation of the NG-test DetecTool OXA-23 for the rapid detection of OXA-23 carbapenemase directly from blood cultures JF - JAC-ANTIMICROBIAL RESISTANCE J2 - JAC-ANTIMICROB RESIST VL - 6 PY - 2024 IS - 2 PG - 4 SN - 2632-1823 DO - 10.1093/jacamr/dlae029 UR - https://m2.mtmt.hu/api/publication/34744814 ID - 34744814 LA - English DB - MTMT ER - TY - JOUR AU - Juhász, Alexandra Csilla AU - Nkolokosa, C. AU - Kambewa, E. AU - Jones, S. AU - Cunningham, L.J. AU - Chammudzi, P. AU - Kapira, D. AU - Namacha, G. AU - Lally, D. AU - Kayuni, S.A. AU - Makaula, P. AU - Musaya, J. AU - Stothard, J.R. TI - An alien intermediate snail host in Malawi - Orientogalba viridis (Quoy and Gaimard, 1832) - A new concern for schistosomiasis transmission in Africa? JF - INTERNATIONAL JOURNAL FOR PARASITOLOGY – PARASITES AND WILDLIFE J2 - INT J PARASITOL-PAR VL - 23 PY - 2024 PG - 4 SN - 2213-2244 DO - 10.1016/j.ijppaw.2024.100919 UR - https://m2.mtmt.hu/api/publication/34744560 ID - 34744560 LA - English DB - MTMT ER - TY - JOUR AU - Kerr, O. AU - Juhász, Alexandra Csilla AU - Jones, S. AU - Stothard, J.R. TI - Human cercarial dermatitis (HCD) in the UK: an overlooked and under-reported nuisance? JF - PARASITES AND VECTORS J2 - PARASITE VECT VL - 17 PY - 2024 IS - 1 PG - 6 SN - 1756-3305 DO - 10.1186/s13071-024-06176-x UR - https://m2.mtmt.hu/api/publication/34719221 ID - 34719221 LA - English DB - MTMT ER - TY - JOUR AU - Fernandez-Pittol, Mariana AU - Bosch, Jordi AU - Balleste-Delpierre, Clara AU - Gonzalez, Camille AU - Vasilakopoulou, Alexandra AU - Berbel, Damaris AU - Riccobono, Eleonora AU - Gatermann, Soeren AU - Kamotsay, Katalin AU - Reissier, Sophie AU - Szabó, Dóra AU - Aszalós, Zoltán AU - Francius, Laura AU - Volland, Herve AU - Stankov-Puges, Milovan AU - Rosenmoller, Magda AU - Naas, Thierry AU - Vila, Jordi TI - Multicenter study to assess the use of BL-DetecTool for the detection of CTX-M-type ESBLs and carbapenemases directly from clinical specimens JF - JOURNAL OF CLINICAL MICROBIOLOGY J2 - J CLIN MICROBIOL PY - 2024 PG - 9 SN - 0095-1137 DO - 10.1128/jcm.01136-23 UR - https://m2.mtmt.hu/api/publication/34666768 ID - 34666768 LA - English DB - MTMT ER -