TY - CHAP AU - Alliquander, Anna AU - Fekete, Mónika AU - Fazekas-Pongor, Vince AU - Madarász, Bálint AU - Forrai, Judit AU - Varga, János Tamás AU - Ungvári, Zoltán István ED - Kryczyk-Poprawa, Agata ED - Forrai, Judit TI - The impact of nutrition on vascular health T2 - Health Preservation and Drug Safety - Progress, Trends and Methods PB - ZOZ Ośrodek UMEA SHINODA-KURACEJO CY - Krakkó SN - 9788395955488 PY - 2024 SP - 49 EP - 51 PG - 3 UR - https://m2.mtmt.hu/api/publication/35217953 ID - 35217953 N1 - [Poszter] LA - English DB - MTMT ER - TY - JOUR AU - Fekete, Mónika AU - Sánta, Balázs AU - Horváth, Alpár AU - Tomisa, Gábor AU - Fazekas-Pongor, Vince AU - Szőllősi, Gergő József AU - Varga, János Tamás TI - COPD-s betegek ambuláns ellátása Magyarországon. demográfiai és klinikai profilok elemzése TS - demográfiai és klinikai profilok elemzése JF - NÉPEGÉSZSÉGÜGY J2 - NÉPEGÉSZSÉGÜGY VL - 101 PY - 2024 IS - 2 SP - 133 EP - 133 PG - 1 SN - 0369-3805 UR - https://m2.mtmt.hu/api/publication/35179028 ID - 35179028 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Pikó, Péter AU - Kovács, Nóra AU - Ádány, Róza TI - Az időskori korlátozottság és azzal összefüggő betegségteher vizsgálata a magyar lakosság körében JF - NÉPEGÉSZSÉGÜGY J2 - NÉPEGÉSZSÉGÜGY VL - 101 PY - 2024 IS - 2 SP - 130 EP - 130 PG - 1 SN - 0369-3805 UR - https://m2.mtmt.hu/api/publication/35179018 ID - 35179018 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Forrai, Judit TI - Az orvos és az orvostörténész Vekerdi László • László Vekerdi – Physician and Medical Historian JF - MAGYAR TUDOMÁNY J2 - MAGYAR TUDOMÁNY VL - 185 PY - 2024 IS - 8 SP - 979 EP - 990 PG - 12 SN - 0025-0325 DO - 10.1556/2065.185.2024.8.2 UR - https://m2.mtmt.hu/api/publication/35178392 ID - 35178392 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ungvári, Zoltán István AU - Fekete, Mónika AU - Fekete, János Tibor AU - Grosso, Giuseppe AU - Ungvári, Anna Sára AU - Győrffy, Balázs TI - Adherence to the Mediterranean diet and its protective effects against colorectal cancer: a meta-analysis of 26 studies with 2,217,404 participants JF - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE) J2 - GEROSCIENCE VL - In press PY - 2024 PG - 17 SN - 2509-2715 DO - 10.1007/s11357-024-01296-9 UR - https://m2.mtmt.hu/api/publication/35162223 ID - 35162223 AB - Colorectal cancer (CRC) is a major global health concern and represents a significant public health challenge in Hungary, where it exhibits some of the highest morbidity and mortality rates in the European Union. The Mediterranean diet has been suggested to reduce the incidence of CRC, but comprehensive evidence from diverse study designs is needed to substantiate this effect. A systematic literature search was conducted in PubMed, ClinicalTrials.gov, CENTRAL, and the Web of Science to identify randomized controlled trials and human clinical trials from 2008 to 2024 to identify relevant studies. Statistical analysis was performed using the https://metaanalysisonline.com web application using a random effects model to estimate the pooled hazard rates (HRs). Forest plots, funnel plots, and Z -score plots were utilized to visualize results. We identified 15 clinical trials and 9 case–control studies, encompassing a total of 2,217,404 subjects. The pooled analysis indicated that adherence to the Mediterranean diet significantly reduced the prevalence of CRC (HR = 0.84, 95% CI = 0.78–0.91, p < 0.01). This protective effect was consistent across sexes, with HRs of 0.85 (95% CI = 0.75–0.97, p = 0.01) for males and 0.88 (95% CI = 0.79–0.99, p = 0.03) for females. Case–control studies specifically showed a substantial effect (HR = 0.51, 95% CI = 0.38–0.68, p < 0.01). Notable heterogeneity was observed across studies, yet the a priori information size was substantially below the cumulative sample size, ensuring sufficient data for reliable conclusions. The findings from this meta-analysis reinforce the protective role of the Mediterranean diet against CRC. The results of this meta-analysis will inform dietary interventions designed to mitigate CRC risk, which are conducted within the framework of the Semmelweis Study, an ongoing comprehensive cohort study at Semmelweis University, designed to explore the multifaceted causes of unhealthy aging in Hungary. These interventions aim to explore the practical application of Mediterranean dietary patterns in reducing CRC incidence among the Hungarian population. LA - English DB - MTMT ER - TY - JOUR AU - Owens, C.D. AU - Pinto, C.B. AU - Mukli, Péter AU - Gulej, R. AU - Velez, F.S. AU - Detwiler, S. AU - Olay, L. AU - Hoffmeister, J.R. AU - Szarvas, Zsófia AU - Murányi, Mihály AU - Péterfi, Anna AU - Pinaffi-Langley, A.C.D.C. AU - Adams, C. AU - Sharps, J. AU - Kaposzta, Z. AU - Prodan, C.I. AU - Kirkpatrick, A.C. AU - Tarantini, Stefano AU - Csiszar, Anna AU - Ungvári, Zoltán István AU - Olson, A.L. AU - Li, G. AU - Balasubramanian, P. AU - Galvan, V. AU - Bauer, A. AU - Smith, Z.A. AU - Dasari, T.W. AU - Whitehead, S. AU - Medapti, M.R. AU - Elahi, F.M. AU - Thanou, A. AU - Yabluchanskiy, A. TI - Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment JF - ALZHEIMERS & DEMENTIA J2 - ALZHEIMERS DEMENT VL - 20 PY - 2024 IS - 8 SP - 5590 EP - 5606 PG - 17 SN - 1552-5260 DO - 10.1002/alz.14072 UR - https://m2.mtmt.hu/api/publication/35113668 ID - 35113668 AB - INTRODUCTION: Mild cognitive impairment (MCI) is a prodromal stage of dementia. Understanding the mechanistic changes from healthy aging to MCI is critical for comprehending disease progression and enabling preventative intervention. METHODS: Patients with MCI and age-matched controls (CN) were administered cognitive tasks during functional near-infrared spectroscopy (fNIRS) recording, and changes in plasma levels of extracellular vesicles (EVs) were assessed using small-particle flow cytometry. RESULTS: Neurovascular coupling (NVC) and functional connectivity (FC) were decreased in MCI compared to CN, prominently in the left-dorsolateral prefrontal cortex (LDLPFC). We observed an increased ratio of cerebrovascular endothelial EVs (CEEVs) to total endothelial EVs in patients with MCI compared to CN, correlating with structural MRI small vessel ischemic damage in MCI. LDLPFC NVC, CEEV ratio, and LDLPFC FC had the highest feature importance in the random Forest group classification. DISCUSSION: NVC, CEEVs, and FC predict MCI diagnosis, indicating their potential as markers for MCI cerebrovascular pathology. Highlights: Neurovascular coupling (NVC) is impaired in mild cognitive impairment (MCI). Functional connectivity (FC) compensation mechanism is lost in MCI. Cerebrovascular endothelial extracellular vesicles (CEEVs) are increased in MCI. CEEV load strongly associates with cerebral small vessel ischemic lesions in MCI. NVC, CEEVs, and FC predict MCI diagnosis over demographic and comorbidity factors. © 2024 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association. LA - English DB - MTMT ER - TY - JOUR AU - Éberhardt, Eszter AU - Simek, Ágnes TI - A társadalmi megítélés hatása a drogfogyasztásra JF - MEDICUS UNIVERSALIS J2 - MED UNIV VL - 57 PY - 2024 IS - 1 SP - 45 EP - 53 PG - 9 SN - 0133-1973 UR - https://m2.mtmt.hu/api/publication/35087610 ID - 35087610 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Ungvári, Zoltán István AU - Murányi, Mihály AU - Gulej, Rafal AU - Negri, Sharon AU - Nyúl-Tóth, Ádám AU - Csik, Boglarka AU - Patai, Roland AU - Conley, Shannon AU - Milan, Madison AU - Bagwell, Jonathan AU - O’Connor, Daniel AU - Tarantini, Amber AU - Yabluchanskiy, Andriy AU - Tóth, Péter József AU - Csiszar, Anna AU - Ungvári, Anna Sára AU - Mukli, Péter AU - Tarantini, Stefano TI - Longitudinal detection of gait alterations associated with hypertension-induced cerebral microhemorrhages in mice: predictive role of stride length and stride time asymmetry and increased gait entropy JF - GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE) J2 - GEROSCIENCE VL - 46 PY - 2024 IS - 5 SP - 4743 EP - 4760 PG - 18 SN - 2509-2715 DO - 10.1007/s11357-024-01210-3 UR - https://m2.mtmt.hu/api/publication/35063232 ID - 35063232 LA - English DB - MTMT ER - TY - JOUR AU - Fekete, Mónika AU - Sánta, Balázs AU - Horváth, Alpár AU - Tomisa, Gábor AU - Szőllősi, Gergő József AU - Varga, János Tamás TI - COPD-s betegek ambuláns ellátása Magyarországon. demográfiai és klinikai profilok elemzése TS - demográfiai és klinikai profilok elemzése JF - MEDICINA THORACALIS (BUDAPEST) J2 - MED THORAC (BP) VL - 77 PY - 2024 IS - 3 SP - 207 EP - 207 PG - 1 SN - 0238-2571 UR - https://m2.mtmt.hu/api/publication/35050716 ID - 35050716 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Szarvas, Zsófia AU - Fekete, Mónika AU - Szőllősi, Gergő József AU - Kup, Katica Anna AU - Horváth, Rita AU - Shimizu, Maya AU - Tsuhiya, Fuko AU - Choi, Ha Eun AU - Wu, Huang-Tzu AU - Fazekas-Pongor, Vince AU - Pete, Kinga AU - Cserjési, Renáta AU - Gőbel, Orsolya AU - Kovács, Orsolya AU - Gyöngyösi, Kata AU - Pintér, Renáta AU - Kolozsvári, Dóra AU - Jáky-Kováts, Zsuzsanna Ágnes AU - Ungvári, Zoltán István AU - Tarantini, Stefano AU - Horváth, Gábor AU - Müller, Veronika AU - Varga, János Tamás TI - A cardiopulmonalis rehabilitáció időtartamának optimalizálása long-COVID szindrómás betegeknél JF - MEDICINA THORACALIS (BUDAPEST) J2 - MED THORAC (BP) VL - 77 PY - 2024 IS - 3 SP - 180 EP - 181 PG - 2 SN - 0238-2571 UR - https://m2.mtmt.hu/api/publication/35050683 ID - 35050683 LA - Hungarian DB - MTMT ER -