@article{MTMT:34066780, title = {Delta 9-tetrahydrocannabinol conserves cardiovascular functions in a rat model of endotoxemia: Involvement of endothelial molecular mechanisms and oxidativenitrative stress}, url = {https://m2.mtmt.hu/api/publication/34066780}, author = {Bányai, Bálint Péter and Répás, C. and Miklós, Zsuzsanna and Johnsen, J. and Horvath, Eszter Mária and Benkő, Rita}, doi = {10.1371/journal.pone.0287168}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {18}, unique-id = {34066780}, year = {2023}, eissn = {1932-6203}, orcid-numbers = {Bányai, Bálint Péter/0000-0001-5531-0661; Miklós, Zsuzsanna/0000-0001-8577-4475; Horvath, Eszter Mária/0000-0002-0517-1269; Benkő, Rita/0000-0001-7740-9128} } @{MTMT:31359099, title = {Guidelines for Local Hyperthermia Treatment in Oncology}, url = {https://m2.mtmt.hu/api/publication/31359099}, author = {Szász, Attila Marcell and Árkosy, Péter and Arrojo, EE and Bakacs, T and Balogh, A and Barich, J and Borbényi, Erika and Chi, KH and Csoszi, T and Daniilidis, L and Douwes, F and Eller, YG and Fiorentini, G and Forika, Gertrud and Herzog, A and Kleef, R and Krenács, Tibor and Lee, SY and Minnaar, CA and Ou, J and Pang, CLK and Papastravrou, A and Parmar, G and Szentmártoni, Gyöngyvér and Szigeti, Gyula Péter and Van, Gool S and Wust, P and Dank, Magdolna}, booktitle = {Challenges and Solutions of Oncological Hyperthermia}, unique-id = {31359099}, year = {2020}, pages = {32-71}, orcid-numbers = {Szász, Attila Marcell/0000-0003-2739-4196; Borbényi, Erika/0000-0002-0425-5540; Forika, Gertrud/0000-0001-9622-1040; Krenács, Tibor/0000-0001-9164-065X; Szentmártoni, Gyöngyvér/0000-0003-1093-4619; Szigeti, Gyula Péter/0000-0003-0411-9992; Dank, Magdolna/0000-0002-4442-8733} } @article{MTMT:31637466, title = {Effects of Testosterone Deficiency and Angiotensin II-Induced Hypertension on the Biomechanics of Intramural Coronary Arteries}, url = {https://m2.mtmt.hu/api/publication/31637466}, author = {Jósvai, Attila and Török, Marianna and Mátrai, Máté and Hetthéssy, Judit and Monori-Kiss, Anna and Makk, Jennifer and Székács, Béla and Nádasy, György László and Várbíró, Szabolcs}, doi = {10.1016/j.jsxm.2020.09.003}, journal-iso = {J SEX MED}, journal = {JOURNAL OF SEXUAL MEDICINE}, volume = {17}, unique-id = {31637466}, issn = {1743-6095}, abstract = {Andropause and hypertension also increase the risk of coronary artery damage.To investigate the effect of testosterone deficiency and hypertension on intramural coronary vessels.4 groups of 8-week-old Sprague-Dawley rats were studied: control male (Co, n=10), orchidectomized male (OCT, n=13), angiotensin (AII) hypertensive male (AII, n=10), and AII hypertensive and OCT (AII + OCT, n=8). Surgical orchidectomy was performed, and an osmotic minipump was inserted for chronic angiotensin II infusion (100 ng/min/kg). After 4 weeks, spontaneous tone and biomechanical properties of the intramural coronary resistance artery were investigated in vitro, by pressure microarteriography.Morphology and biomechanics of the intramural coronaries were evaluated: the outer diameter, wall thickness-to-lumen diameter ratio, and tangential wall stress in the contracted and relaxed states.The outer diameter was reduced in OCT and AII + OCT groups (on 50 mmHg 315 ± 20 Co; 237 ± 21 OCT; 291 ± 16 AII, and 166 ± 12 μm AII + OCT). The increased wall thickness-to-lumen diameter ratio resulted in lower tangential wall stress in AII + OCT rats (on 50 mmHg 19 ± 2 Co; 24 ± OCT; 26 ± 5 AII, and 9 ± 1 kPa AII + OCT). Spontaneous tone was increased in the hypertensive rats (AII and AII + OCT groups) (on 50 mmHg 7.7 ± 1.8 Co; 6.1 ± 1.4 OCT; 14.5 ± 3.0 AII, and 17.4 ± 4.1 % AII + OCT).Andropause alone can be considered as a cardiovascular risk factor that will further exacerbate vascular damage in hypertension.A limitation of our study is that it was performed on relatively young rats, and the conclusions might not apply to coronary remodelling in older animals with slower adaptation processes.Testosterone deficiency and hypertension damage the mechanical adaptation of the vessel wall additively: double noxa caused inward eutrophic remodeling and increased tone. Jósvai A, Török M, Mátrai M, et al. Effects of Testosterone Deficiency and Angiotensin II-Induced Hypertension on the Biomechanics of Intramural Coronary Arteries. J Sex Med 2020;XX:XXX-XXX.}, keywords = {HYPERTENSION; testosterone; Biomechanics; Castration; Rat Andropause Model; Resistance Coronary Artery}, year = {2020}, eissn = {1743-6109}, pages = {2322-2330}, orcid-numbers = {Jósvai, Attila/0000-0002-2793-9152; Török, Marianna/0000-0002-2832-0626; Hetthéssy, Judit/0000-0001-8274-5257; Monori-Kiss, Anna/0000-0002-4315-8743; Székács, Béla/0000-0002-3007-8568; Nádasy, György László/0000-0003-2057-2391; Várbíró, Szabolcs/0000-0002-7109-6906} } @article{MTMT:3328964, title = {Hyperthermia dosing and depth of effect}, url = {https://m2.mtmt.hu/api/publication/3328964}, author = {Szász, Olivér and Szigeti, Gyula Péter and Vancsik, Tamás and Szász, András}, doi = {10.4236/ojbiphy.2018.81004}, journal-iso = {OPEN J BIOPHYS}, journal = {OPEN JOURNAL OF BIOPHYSICS}, volume = {8}, unique-id = {3328964}, issn = {2164-5396}, year = {2018}, eissn = {2164-5388}, pages = {31-48}, orcid-numbers = {Szigeti, Gyula Péter/0000-0003-0411-9992} } @article{MTMT:3380109, title = {Foszfolipáz C epszilon szerepe a nitrogén-monoxid hiányhoz kapcsolódó hipertóniában [The role of phospholipase C epsilon in nitric oxide deficiency associated hypertension]}, url = {https://m2.mtmt.hu/api/publication/3380109}, author = {Németh, Tamás and Ruisanchez, Éva and Hricisák, László and Fülöp, Ágnes and Iring, András and Káldi, Krisztina and Várnai, Péter and Smrcka, Alan V and Merkely, Béla Péter and Offermanns, Stefan and Benyó, Zoltán}, journal-iso = {CARDIOL HUNG}, journal = {CARDIOLOGIA HUNGARICA}, volume = {48}, unique-id = {3380109}, issn = {0133-5596}, year = {2018}, eissn = {1588-0230}, pages = {C35-C36}, orcid-numbers = {Ruisanchez, Éva/0000-0001-7779-226X; Hricisák, László/0000-0001-8320-2166; Iring, András/0000-0002-3087-4337; Várnai, Péter/0000-0002-7777-806X; Merkely, Béla Péter/0000-0001-6514-0723; Benyó, Zoltán/0000-0001-6015-0359} } @article{MTMT:3200408, title = {Connections between Warburg's and Szentgyorgyi's Approach about the Causes of Cancer}, url = {https://m2.mtmt.hu/api/publication/3200408}, author = {Szigeti, Gyula Péter and Szasz, O and Hegyi, Gabriella}, journal-iso = {JOURNAL OF NEOPLASM}, journal = {JOURNAL OF NEOPLASM}, volume = {1}, unique-id = {3200408}, year = {2017}, eissn = {2576-3903}, orcid-numbers = {Szigeti, Gyula Péter/0000-0003-0411-9992} } @article{MTMT:30345075, title = {Electrokinetics of Temperature for Development and Treatment of Effusions}, url = {https://m2.mtmt.hu/api/publication/30345075}, author = {Szasz, Oliver and Szigeti, Gyula Péter and Szász, Attila Marcell}, doi = {10.4236/abb.2017.811032}, journal-iso = {ADV BIOS BIO}, journal = {ADVANCES IN BIOSCIENCE AND BIOTECHNOLOGY}, volume = {8}, unique-id = {30345075}, issn = {2156-8456}, year = {2017}, eissn = {2156-8502}, pages = {434-449}, orcid-numbers = {Szigeti, Gyula Péter/0000-0003-0411-9992; Szász, Attila Marcell/0000-0003-2739-4196} } @article{MTMT:3073859, title = {Estrogen therapy may counterbalance eutrophic remodeling of coronary arteries and increase bradykinin relaxation in a rat model of menopausal hypertension.}, url = {https://m2.mtmt.hu/api/publication/3073859}, author = {Mátrai, Máté and Hetthéssy, Judit and Nádasy, György László and Székács, Béla and Mericli, M and Ács, Nándor and Monos, Emil and Arbib, N and Várbíró, Szabolcs}, doi = {10.1097/GME.0000000000000654}, journal-iso = {MENOPAUSE}, journal = {MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY}, volume = {23}, unique-id = {3073859}, issn = {1072-3714}, abstract = {OBJECTIVE: Hypertension causes adverse remodeling and vasomotor alterations in coronaries. Hormones such as estrogen may help counterbalance some of these effects. The aim of this study was to analyze the effects of ovariectomy and estrogen therapy in a rat model of menopausal hypertension induced by angiotensin II (AII). METHODS: We investigated diameter, tone, and mechanics of intramural coronaries taken from ovariectomized female rats (n = 11) that received chronic AII treatment to induce hypertension, and compared the results with those found in female rats that were also given estrogen therapy (n = 11). The "hypertensive control" group (n = 11) underwent an abdominal sham operation, and received AII. After 4 weeks of AII treatment, side branches of left anterior descendent coronary (approximately 200 mum in diameter) were isolated, cannulated with plastic microcannulas at both ends, and studied in vitro in a vessel chamber. The inner and outer diameter of the arteries were measured by microangiometry, and spontenuous tone, wall thickness, wall cross-sectional area, tangential stress, incremental distensibility, circumferential incremental elastic modulus, thromboxane agonist-induced tone, and bradykinin-induced dilation were calculated. RESULTS: In hypertension, intramural small coronaries show inward eutrophic remodeling after ovariectomy comparing with hypertensive controls. Estrogen therapy had an opposite effect on vessel diameter. Hormone therapy led to an increase in spontaneous tone, allowing for greater dilatative capacity. CONCLUSIONS: Estrogen may therefore be considered to counterbalance some of the adverse changes seen in the wall of intramural coronaries in the early stages of chronic hypertension.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0.}, year = {2016}, eissn = {1530-0374}, pages = {778-783}, orcid-numbers = {Hetthéssy, Judit/0000-0001-8274-5257; Nádasy, György László/0000-0003-2057-2391; Székács, Béla/0000-0002-3007-8568; Ács, Nándor/0000-0002-1919-1869; Monos, Emil/0000-0001-5423-3887; Várbíró, Szabolcs/0000-0002-7109-6906} } @misc{MTMT:3085400, title = {KÉT HÓNAPOS QUERCETIN SZUPPLEMENTÁCIÓ MÉRSÉKELI A KORONÁRIA ARTERIOLÁK HÁLÓZATI TULAJDONSÁGAINAK HIPERTÓNIA INDUKÁLTA KÓROS ÁTÉPÜLÉSÉT}, url = {https://m2.mtmt.hu/api/publication/3085400}, author = {Monori-Kiss, Anna and Lónyi, F and Nádasy, György László}, unique-id = {3085400}, year = {2016}, pages = {148-148}, orcid-numbers = {Monori-Kiss, Anna/0000-0002-4315-8743; Nádasy, György László/0000-0003-2057-2391} } @article{MTMT:3090568, title = {Connections between the Specific Absorption Rate and the local Temperature}, url = {https://m2.mtmt.hu/api/publication/3090568}, author = {Szász, Olivér and Szigeti, Gyula Péter and Szász, András}, journal-iso = {OPEN J BIOPHYS}, journal = {OPEN JOURNAL OF BIOPHYSICS}, volume = {6}, unique-id = {3090568}, issn = {2164-5396}, year = {2016}, eissn = {2164-5388}, pages = {53-74}, orcid-numbers = {Szigeti, Gyula Péter/0000-0003-0411-9992} }