@article{MTMT:34797745,
	title = {RevCAR-expressing immune effector cells for targeting of Fn14-positive glioblastoma},
	url = {https://m2.mtmt.hu/api/publication/34797745},
	author = {Saleh, H.A. and Mitwasi, N. and R., Loureiro L. and Kegler, A. and Soto, K.E.G. and Hoffmann, L. and Crespo, E. and Arndt, C. and Bergmann, Ralf Konrad and Bachmann, M. and Feldmann, A.},
	doi = {10.1038/s41417-024-00766-8},
	journal-iso = {CANCER GENE THER},
	journal = {CANCER GENE THERAPY},
	unique-id = {34797745},
	issn = {0929-1903},
	year = {2024},
	eissn = {1476-5500}
}

@article{MTMT:34794477,
	title = {A meta-analysis on first-trimester blood count parameters—is the neutrophil-to-lymphocyte ratio a potentially novel method for first-trimester preeclampsia screening?},
	url = {https://m2.mtmt.hu/api/publication/34794477},
	author = {Mészáros, Balázs and Veres, Dániel and Nagyistók, Luca and Kovács, Bence Géza and Kukor, Zoltán and Valent, Sándor},
	doi = {10.3389/fmed.2024.1336764},
	journal-iso = {FRONT MED},
	journal = {FRONTIERS IN MEDICINE},
	volume = {11},
	unique-id = {34794477},
	year = {2024},
	eissn = {2296-858X},
	orcid-numbers = {Veres, Dániel/0000-0002-9687-3556; Kovács, Bence Géza/0000-0002-5578-1858; Kukor, Zoltán/0000-0002-7250-2160; Valent, Sándor/0000-0003-1098-1861}
}

@article{MTMT:34789637,
	title = {Water-Insoluble, Thermostable, Crosslinked Gelatin Matrix for Soft Tissue Implant Development},
	url = {https://m2.mtmt.hu/api/publication/34789637},
	author = {Varga, Viktória Dóra and Smeller, László and Várdai, Róbert and Kocsis, Bence and Zsoldos, Ibolya and Cruciani, Sara and Pala, Renzo and Hornyák, István},
	doi = {10.3390/ijms25084336},
	journal-iso = {INT J MOL SCI},
	journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES},
	volume = {25},
	unique-id = {34789637},
	issn = {1661-6596},
	abstract = {In this present study, the material science background of crosslinked gelatin (GEL) was investigated. The aim was to assess the optimal reaction parameters for the production of a water-insoluble crosslinked gelatin matrix suitable for heat sterilization. Matrices were subjected to enzymatic degradation assessments, and their ability to withstand heat sterilization was evaluated. The impact of different crosslinkers on matrix properties was analyzed. It was found that matrices crosslinked with butanediol diglycidyl ether (BDDE) and poly(ethylene glycol) diglycidyl ether (PEGDE) were resistant to enzymatic degradation and heat sterilization. Additionally, at 1 v/v % crosslinker concentration, the crosslinked weight was lower than the starting weight, suggesting simultaneous degradation and crosslinking. The crosslinked weight and swelling ratio were optimal in the case of the matrices that were crosslinked with 3% and 5% v/v BDDE and PEGDE. FTIR analysis confirmed crosslinking, and the reduction of free primary amino groups indicated effective crosslinking even at a 1% v/v crosslinker concentration. Moreover, stress–strain and compression characteristics of the 5% v/v BDDE crosslinked matrix were comparable to native gelatin. Based on material science measurements, the crosslinked matrices may be promising candidates for scaffold development, including properties such as resistance to enzymatic degradation and heat sterilization.},
	keywords = {Biomaterials; Material science; crosslinked gelatin; scaffold development},
	year = {2024},
	eissn = {1422-0067},
	orcid-numbers = {Varga, Viktória Dóra/0009-0005-8769-1653; Smeller, László/0000-0002-3643-3268; Hornyák, István/0000-0002-7183-8973}
}

@article{MTMT:34788583,
	title = {Hyaluronate acid plus platelet-rich plasma is superior to steroids for pain relief less than 6 months using injection therapy of partial rotator cuff tears : A systematic review and network meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34788583},
	author = {Weninger, Viktor and Agócs, Gergely and Kovács, Norbert and Váncsa, Szilárd and Hergár, Luca and Baek, Chan Ju and Hegyi, Péter and Holnapy, Gergely and Skaliczki, Gábor},
	doi = {10.1016/j.arthro.2024.03.035},
	journal-iso = {ARTHROSCOPY},
	journal = {ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY},
	unique-id = {34788583},
	issn = {0749-8063},
	abstract = {We conducted our network meta-analysis to compare the efficacy of the steroid injections to other injectable therapies in partial-thickness rotator cuff tears (PTRCTs).A systematic literature search was performed until October 25, 2021 in three databases (CENTRAL, Embase, MEDLINE). Eligible studies compared the efficacy of steroid, hyaluronic acid (HA), platelet-rich plasma (PRP), the combination of HA and PRP (HA+PRP), and adipose-derived regenerative cells (ADRC) in RC tears. The primary outcomes were the Visual Analogue Scale (VAS), Constant Murley Score (CMS), and American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form. Using paired and network meta-analysis, we calculated pooled mean differences (MDs) with 95% confidence intervals (CIs).We included a total of seven articles in the quantitative synthesis. In shorter periods, the HA+PRP combination was superior to the other substances we investigated (HA+PRP: VAS (0-4 weeks): MD: -0.99 [CI = -1.62, -0.36]; CMS (0-3 months): 20.56 [CI = 16.18, 24.94]. This combination was followed by the use of HA or PRP alone, depending on the duration of follow-up and the outcome being studied. In our study, short-term results suggest that saline is superior to steroids for partial tears, but this trend is reversed at six-month follow-up.Our results suggest the combination of HA and PRP to be a more effective therapeutic option for partial RC ruptures for short terms, but there is no significant difference after 6 months.II, Included of Level of Evidence studies I-II.},
	keywords = {rotator cuff; Conservative therapy; Injection therapy; subacromial injection; shoulder surgery; partial rotator cuff tear; [Meta-analysis]},
	year = {2024},
	eissn = {1526-3231},
	orcid-numbers = {Weninger, Viktor/0000-0001-8192-4632; Agócs, Gergely/0000-0003-2489-3790; Váncsa, Szilárd/0000-0002-9347-8163; Hegyi, Péter/0000-0003-0399-7259; Skaliczki, Gábor/0000-0002-8555-5114}
}

@article{MTMT:34788581,
	title = {Nonoperative Treatment as an Option for Isolated Anterior Cruciate Ligament Injury : A Systematic Review and Meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34788581},
	author = {de Jonge, Robert and Máté, Miklós and Kovács, Norbert and Imrei, Marcell and Pap, Károly and Agócs, Gergely and Váncsa, Szilárd and Hegyi, Péter and Pánics, Gergely},
	doi = {10.1177/23259671241239665},
	journal-iso = {ORTHOP J SPORTS MED},
	journal = {ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE},
	volume = {12},
	unique-id = {34788581},
	abstract = {An anterior cruciate ligament (ACL) tear is a risk factor for early osteoarthritis (OA) onset. Generally, ACL reconstruction (ACLR) is associated with better outcomes. However, there is a lack of evidence regarding the effect of operative versus nonoperative treatment for preventing premature knee OA in isolated ACL tears while achieving good functional outcomes.The purpose of the study was to compare the outcomes of ACLR to primarily nonoperative management of isolated ACL tears. It was hypothesized that the outcomes between treatment types would be similar.Systematic review; Level of evidence, 3.This systematic review was registered on the International Prospective Register of Systematic Reviews (PROSPERO) (registration No. CRD42021285901) and was conducted according to the Cochrane Handbook guidelines. We systematically searched for randomized and nonrandomized studies that compared ACLR with nonoperative treatments in isolated ACL tears in 3 databases until October 25, 2021. The risk of bias and quality of evidence of the included studies was assessed in accordance with the Cochrane guidelines. The primary outcome was radiologic signs of OA, and the secondary outcomes were functional parameters. Using the common effects model, we calculated pooled mean differences (MDs) and odds ratios (ORs) with 95% CIs.Five studies-2 randomized controlled trials (RCTs) and 3 retrospective non-RCTs-were included. There was a moderate risk of bias in 2 studies and a serious risk of bias in 1 study. The quality of evidence was rated low because of the higher risk of bias and inconsistency. Nonoperatively treated knees showed a trend toward lower odds of developing radiological signs of OA (OR, 1.84 [95% CI, 0.90 to 3.75]); however, surgically reconstructed knees had significantly better stability (MD, -2.44 [95% CI, -3.21 to -1.66 ]) and a trend toward better but clinically not meaningful Lysholm scores (MD, 2.88 [95% CI, -1.09 to 6.85]). The qualitative synthesis showed that surgical reconstruction was protective against subsequent injuries but not superior when returning to previous activity levels or various functional tests.Findings indicated that there is no certain evidence that ACLR for an isolated ACL tear is superior to nonoperative treatment. Clinicians should consider nonoperative treatments with a well-designed rehabilitative program as a primary option. However, these findings must be interpreted with caution because of low study quality and high risk of bias.},
	keywords = {RECONSTRUCTION; Cartilage; surgery; KNEE; anterior cruciate ligament; Conservative; nonoperative; [Meta-analysis]},
	year = {2024},
	eissn = {2325-9671},
	orcid-numbers = {Imrei, Marcell/0000-0003-0175-7462; Pap, Károly/0000-0003-1063-4026; Agócs, Gergely/0000-0003-2489-3790; Váncsa, Szilárd/0000-0002-9347-8163; Hegyi, Péter/0000-0003-0399-7259; Pánics, Gergely/0000-0002-4504-3923}
}

@article{MTMT:34763940,
	title = {Morphology of the papilla can predict procedural safety and efficacy of ERCP-a systematic review and meta-analysis.},
	url = {https://m2.mtmt.hu/api/publication/34763940},
	author = {Tari, Edina and Gagyi , Endre and Rancz, Anett and Veres, Dániel and Váncsa, Szilárd and Hegyi, Péter Jenő and Hagymási, Krisztina and Hegyi, Péter and Erőss, Bálint Mihály},
	doi = {10.1038/s41598-024-57758-9},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {14},
	unique-id = {34763940},
	issn = {2045-2322},
	abstract = {Endoscopic Retrograde Cholangiopancreatography (ERCP) is the primary therapeutic procedure for pancreaticobiliary disorders, and studies highlighted the impact of papilla anatomy on its efficacy and safety. Our objective was to quantify the influence of papilla morphology on ERCP outcomes. We systematically searched three medical databases in September 2022, focusing on studies detailing the cannulation process or the rate of adverse events in the context of papilla morphology. The Haraldsson classification served as the primary system for papilla morphology, and a pooled event rate with a 95% confidence interval was calculated as the effect size measure. Out of 17 eligible studies, 14 were included in the quantitative synthesis. In studies using the Haraldsson classification, the rate of difficult cannulation was the lowest in type I papilla (26%), while the highest one was observed in the case of type IV papilla (41%). For post-ERCP pancreatitis, the event rate was the highest in type II papilla (11%) and the lowest in type I and III papilla (6-6%). No significant difference was observed in the cannulation failure and post-ERCP bleeding event rates between the papilla types. In conclusion, certain papilla morphologies are associated with a higher rate of difficult cannulation and post-ERCP pancreatitis.},
	keywords = {[Meta-analysis]},
	year = {2024},
	eissn = {2045-2322},
	orcid-numbers = {Tari, Edina/0000-0002-8540-0614; Veres, Dániel/0000-0002-9687-3556; Váncsa, Szilárd/0000-0002-9347-8163; Hagymási, Krisztina/0000-0002-5859-1320; Hegyi, Péter/0000-0003-0399-7259; Erőss, Bálint Mihály/0000-0003-3658-8427}
}

@article{MTMT:34724664,
	title = {PtdIns4p is required for the autophagosomal recruitment of STX17 (syntaxin 17) to promote lysosomal fusion},
	url = {https://m2.mtmt.hu/api/publication/34724664},
	author = {Laczkó-Dobos, Hajnalka and Bhattacharjee, Arindam and Maddali, Asha Kiran and Kincses, András and Abuammar, Hussein and Sebőkné Nagy, Krisztina and Páli, Tibor and Dér, András and Hegedűs, Tamás and Csordás, Gábor and Juhász, Gábor},
	doi = {10.1080/15548627.2024.2322493},
	journal-iso = {AUTOPHAGY},
	journal = {AUTOPHAGY},
	volume = {AiP},
	unique-id = {34724664},
	issn = {1554-8627},
	year = {2024},
	eissn = {1554-8635},
	orcid-numbers = {Páli, Tibor/0000-0003-1649-1097; Hegedűs, Tamás/0000-0002-0331-9629; Csordás, Gábor/0000-0001-6871-6839; Juhász, Gábor/0000-0001-8548-8874}
}

@article{MTMT:34687462,
	title = {Arthroscopic capsular release is more effective in pain relief than conservative treatment in patients with frozen shoulder},
	url = {https://m2.mtmt.hu/api/publication/34687462},
	author = {Skaliczki, Gábor and Kovács, Krisztián and Antal, Imre and Sallai, Imre and Kovács, B. and Nyőgér, Z. and Géresi, Á. and Kiss, Balázs and Várnagy, Anna},
	doi = {10.1186/s12891-024-07275-7},
	journal-iso = {BMC MUSCULOSKEL DIS},
	journal = {BMC MUSCULOSKELETAL DISORDERS},
	volume = {25},
	unique-id = {34687462},
	issn = {1471-2474},
	year = {2024},
	eissn = {1471-2474},
	orcid-numbers = {Skaliczki, Gábor/0000-0002-8555-5114; Sallai, Imre/0000-0003-4123-1289; Kiss, Balázs/0000-0002-2347-5928}
}

@article{MTMT:34682498,
	title = {The risk of developing splanchnic vein thrombosis in acute pancreatitis increases 3 days after symptom onset: A systematic review and meta-analysis},
	url = {https://m2.mtmt.hu/api/publication/34682498},
	author = {Borbély, Ruben Zsolt and Szalai, Eszter and Philip, Bryan Mangalath and Dobszai, Dalma and Teutsch, Brigitta and Zolcsák, Ádám and Veres, Dániel and Erőss, Bálint Mihály and Gellért, Bálint and Hegyi, Péter Jenő and Hegyi, Péter and Faluhelyi, Nándor},
	doi = {10.1002/ueg2.12550},
	journal-iso = {UEG JOURNAL},
	journal = {UNITED EUROPEAN GASTROENTEROLOGY JOURNAL},
	unique-id = {34682498},
	issn = {2050-6406},
	abstract = {Abstract Background Splanchnic vein thrombosis is a complication of acute pancreatitis (AP) and is likely often underdiagnosed. Objectives We aimed to understand the time course and risk factors of splanchnic vein thrombosis in the early phase of AP. Methods A systematic search was conducted using the PRISMA guidelines (PROSPERO registration CRD42022367578). Inclusion criteria were appropriate imaging techniques in adult AP patients, studies that reported splanchnic vein thrombosis data from the early phase, and reliable information on the timing of imaging in relation to the onset of pancreatitis symptoms or hospital admission. The proportion of patients with thrombosis with 95% confidence intervals (CI) was calculated using random-effects meta-analyses, and multiple subgroup analyses were performed. Results Data from 1951 patients from 14 studies were analyzed. The proportion of patients with splanchnic vein thrombosis within 12 days after symptom onset was 0.13 (CI 0.07?0.23). The occurrence was lowest at 0.06 (CI 0.03?0.1) between 0 and 3 days after symptom onset, and increased fourfold to 0.23 (CI 0.16?0.31) between 3 and 11 days. On hospital admission, the proportion of patients affected was 0.12 (CI 0.02?0.49); it was 0.17 (CI 0.03?0.58) 1?5 days after admission. The prevalence in mild, moderate, and severe AP was 0.15 (CI 0.05?0.36), 0.26 (CI 0.15?0.43), and 0.27 (CI 0.17?0.4), respectively. Alcoholic etiology (0.31, CI 0.13?0.58) and pancreatic necrosis (0.55, CI 0.29?0.78, necrosis above 30%) correlated with increased SVT prevalence. Conclusion The risk of developing splanchnic vein thrombosis is significant in the early stages of AP and may affect up to a quarter of patients. Alcoholic etiology, pancreatic necrosis, and severity may increase the prevalence of splanchnic vein thrombosis.},
	keywords = {portal vein thrombosis; splenic vein thrombosis; Superior mesenteric vein thrombosis; portosplenomesenteric venous thrombosis; [Meta-analysis]},
	year = {2024},
	eissn = {2050-6414},
	orcid-numbers = {Teutsch, Brigitta/0000-0002-9530-7886; Zolcsák, Ádám/0000-0002-9128-4867; Veres, Dániel/0000-0002-9687-3556; Erőss, Bálint Mihály/0000-0003-3658-8427; Gellért, Bálint/0009-0002-7896-1541; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:34675150,
	title = {FLT3-directed UniCAR T-cell therapy of acute myeloid leukaemia (vol 202, pg 1137, 2023)},
	url = {https://m2.mtmt.hu/api/publication/34675150},
	author = {Peschke, J. C. and Bergmann, Ralf Konrad and Mehnert, M. and Soto, K. E. Gonzalez and Loureiro, L. R. and Mitwasi, N. and Kegler, A. and Altmann, H. and Wobus, M. and Neuber, C. and Máthé, Domokos and Szigeti, Krisztián and Feldmann, A. and Bornhaeuser, M. and Bachmann, M. and Fasslrinner, F. and Arndt, C.},
	doi = {10.1111/bjh.19328},
	journal-iso = {BRIT J HAEMATOL},
	journal = {BRITISH JOURNAL OF HAEMATOLOGY},
	unique-id = {34675150},
	issn = {0007-1048},
	year = {2024},
	eissn = {1365-2141}
}