@misc{MTMT:32118490, title = {The indirect effect of FFFS sensitivity on substance use through negative affectivity is moderated by BIS sensitivity and inattention symptoms in adolescents.}, url = {https://m2.mtmt.hu/api/publication/32118490}, author = {Rádosi, Alexandra and Sebők-Welker, Tünde Éva and Kovács-Posta, Evelyn Csenge and Hámori, György and Zubovics, Evelin Alexa and Ágrez, Kristóf and Pászthy, Bea and Réthelyi, János and Ulbert, István and Bunford, Nóra}, unique-id = {32118490}, year = {2021}, orcid-numbers = {Rádosi, Alexandra/0000-0003-1004-6611; Sebők-Welker, Tünde Éva/0000-0002-2007-6657; Ágrez, Kristóf/0000-0002-4896-5966; Pászthy, Bea/0000-0002-8009-3811; Réthelyi, János/0000-0002-3641-012X; Ulbert, István/0000-0001-9941-9159; Bunford, Nóra/0000-0002-9645-604X} } @article{MTMT:31612951, title = {A novel virtual reality‐based Theory of Mind intervention for outpatients with schizophrenia: a proof-of-concept pilot study}, url = {https://m2.mtmt.hu/api/publication/31612951}, author = {Vass, Edit and Simon, Viktória and Fekete, Zita and Lencse, Laura and Ecseri, Mária and Kis, Balázs and Simon, Lajos}, doi = {10.1002/cpp.2519}, journal-iso = {CLIN PSYCHOL PSYCHOT}, journal = {CLINICAL PSYCHOLOGY & PSYCHOTHERAPY}, volume = {28}, unique-id = {31612951}, issn = {1063-3995}, year = {2021}, eissn = {1099-0879}, pages = {727-738}, orcid-numbers = {Vass, Edit/0000-0002-8858-7277; Simon, Lajos/0000-0002-5180-9040} } @article{MTMT:31604240, title = {Neuropsychiatric symptoms, quality of life and caregivers’ burden in dementia}, url = {https://m2.mtmt.hu/api/publication/31604240}, author = {Majer, Réka and Adeyi, Olar and Bagoly, Zsuzsa and Simon, Viktória and Csiba, László and Kardos, László and Hortobágyi, Tibor and Frecska, Ede}, doi = {10.1515/med-2020-0124}, journal-iso = {OPEN MED-WARSAW}, journal = {OPEN MEDICINE}, volume = {15}, unique-id = {31604240}, issn = {2391-5463}, year = {2020}, eissn = {2391-5463}, pages = {905-914}, orcid-numbers = {Bagoly, Zsuzsa/0000-0001-5314-5607; Hortobágyi, Tibor/0000-0001-5732-7942} } @article{MTMT:3401876, title = {Interventions for the treatment of theory of mind deficits in schizophrenia: Systematic literature review}, url = {https://m2.mtmt.hu/api/publication/3401876}, author = {Vass, Edit and Fekete, Zita and Simon, Viktória and Simon, Lajos}, doi = {10.1016/j.psychres.2018.05.001}, journal-iso = {PSYCHIAT RES}, journal = {PSYCHIATRY RESEARCH}, volume = {267}, unique-id = {3401876}, issn = {0165-1781}, abstract = {Theory of Mind (ToM) plays a central role in regulating social interactions and its impairment is consistently reported in schizophrenia. Regarding schizophrenia, ToM is usually discussed as a sub-domain of social cognition. Since social cognitive deficits have drawn the attention of researchers, a variety of novel treatment techniques and approaches targeting social cognitive deficits have been developed. Encouraging results have repeatedly been reported on the modifiability of social cognitive impairment through these techniques. However, emotional perception seems to be over-represented in these approaches at the expense of other areas, such as ToM. This article presents a systematic review on the social cognitive interventions of the last 10 years, which focused on the remediation of ToM or used techniques primarily focusing on one or more social cognitive domains other than ToM, but with hypothetical effects on it. The aim of our systematic review was to compare these intervention techniques in order to see how effective they are in the remediation of ToM, and to find the best techniques to ameliorate ToM deficits in schizophrenia. According to our findings targeted ToM intervention produced more improvement in ToM tasks, while data regarding non-ToM interventions showed contradictory results with limited effects on ToM.}, year = {2018}, eissn = {1872-7123}, pages = {37-47}, orcid-numbers = {Vass, Edit/0000-0002-8858-7277; Simon, Lajos/0000-0002-5180-9040} } @article{MTMT:31261034, title = {Münchhausen by proxy-szindróma : a gyermekbántalmazás igen veszélyes formája}, url = {https://m2.mtmt.hu/api/publication/31261034}, author = {Baran, Brigitta and Czenner, Zsuzsa}, journal-iso = {MEDICAL TRIBUNE}, journal = {MEDICAL TRIBUNE}, volume = {15}, unique-id = {31261034}, issn = {1589-1283}, abstract = {A Münchhausen-szindróma speciális formája a gyermekek sérelmére elkövetett Münchhausen by proxy-szindróma, amelynek a felismerése és a megfelelő intézkedések megtétele alapvető fontosságú a bántalmazott gyermekek súlyos egészségkárosodásának, szélsőséges esetben halálának a megelőzése érdekében. A szindróma jogi és igazságügyi pszichiátriai szakértői megítélése ellentmondásos.}, keywords = {Pszichiátria; MÜNCHAUSEN-SZINDRÓMA; GYERMEKKÍNZÁS}, year = {2017}, pages = {10-11}, orcid-numbers = {Baran, Brigitta/0000-0002-3473-0680} } @article{MTMT:3117382, title = {Treatment patterns of schizophrenia based on the data from seven Central and Eastern European Countries.}, url = {https://m2.mtmt.hu/api/publication/3117382}, author = {Szkultecka-Debek, M and Miernik, K and Stelmachowski, J and Jakovljevic, M and Jukic, V and Aadamsoo, K and Janno, S and Bitter, István and Tolna, Judit and Jarema, M and Jankovic, S and Pecenak, J and Vavrusova, L and Tavcar, R and Walczak, J and Talbot, D and Augustynska, J}, journal-iso = {PSYCHIAT DANUB}, journal = {PSYCHIATRIA DANUBINA}, volume = {28}, unique-id = {3117382}, issn = {0353-5053}, abstract = {OBJECTIVE: The aim is to analyze how schizophrenia is pharmacologically treated in seven CEE countries: Croatia, Estonia, Hungary, Poland, Serbia, Slovakia and Slovenia. METHODS: Psychiatrists from selected centers in each of participating countries were asked to complete a pre-defined questionnaire on their current clinical practice. Information on protocols and resource utilization in schizophrenia treatment was included and derived from randomly selected patient medical records. Expert opinions on country-wide treatment patterns were additionally sought. This sub-analysis focuses on pharmacological treatment patterns in the last six months and over the course of the disease. RESULTS: 961 patients' data show that during last six months the most commonly prescribed medications were oral atypical antipsychotics: olanzapine (n=268), clozapine (n=234) and risperidone (n=160). The most frequently prescribed atypical antipsychotics over course of disease were: risperidone (54.5%), olanzapine (52.4%) and clozapine (35.1%), along with haloperidol (39.3%). Experts reported risperidone (four countries) and olanzapine (three countries) as first-line treatment, with the same two medications prescribed as second-line treatment. Clozapine was the most reported medication for refractory patients. Approximately 22% of patients received polypharmacy with antipsychotics in at least one period over the disease course. Mean time since diagnosis was 13.1 years and on average 4.8 treatment courses received during that period. Anxiolytics (70%), antidepressants (42%), mood-stabilizers (27%) were also prescribed, with diazepam (35.4%), sertraline (10.5%), valproic acid (17.5%) the most commonly reported, respectively, in each group. The most frequently reported treatment change was switch from one oral atypical antipsychotic to another (51%). CONCLUSION: Oral atypical antipsychotics, mostly older drugs (risperidone, olanzapine, clozapine), were most commonly prescribed for schizophrenia treatment in participating countries. Given that results are from the first large-scale analysis of RWD, we believe these findings can be a benchmark for future real-world studies, which could contribute to the optimization of treatment for this debilitating disease.}, year = {2016}, eissn = {1849-0867}, pages = {234-242}, orcid-numbers = {Bitter, István/0000-0002-9464-4709; Tolna, Judit/0000-0002-2358-7292} } @article{MTMT:3098562, title = {Catatonia in disulfiram intoxication - a case report and a brief overview of the literature [Diszulfirám mérgezéshez társuló katatónia – esetismertetés és rövid irodalmi áttekintés]}, url = {https://m2.mtmt.hu/api/publication/3098562}, author = {Takács, Rozália and Milan, F and Ungvari, GS and Faludi, Gábor and Gazdag Gábor, László}, journal-iso = {NEUROPSYCHOPHARM HUNG}, journal = {NEUROPSYCHOPHARMACOLOGIA HUNGARICA}, volume = {18}, unique-id = {3098562}, issn = {1419-8711}, abstract = {Catatonic syndromes could accompany a variety of psychiatric and medical conditions. The most common conditions underlying catatonia are affective disorders followed by schizophrenia, but several medical conditions including intoxications affecting the central nervous system can also present with catatonic signs and symptoms. Therapeutic doses of disulfiram could induce catatonia with or without accompanying psychosis or mood disorder. A case of disulfiram intoxication manifesting with catatonia is reported here together with a brief overview of the literature. A patient was admitted to the toxicology ward after a suicide attempt with approximately 20 g of disulfiram. On transfer to the psychiatric ward, she was sitting still, in a semi-stuporous state and displayed motiveless resistance to instructions or attempts to move (active negativism). She was unresponsive to most of the questions (mutism), occasionally verbigerated 1-2 words and stared for more than 20 seconds between shifting attention. After developing a comatosus state her treatment continued at the toxicology ward, where a contrast-enhanced computer tomography scan revealed bilateral emollition of 1.5 cm diameter in both nucleus lentiformis at the level of the third ventricle. Following treatment her condition improved and she benefited of rehabilitation facility and a second psychiatric treatment. She was discharged free of neurological and psychiatric symptoms. In conclusion, we underscore the importance of accurate diagnosis of the underlying psychiatric or medical condition when encountering a fast emerging catatonic syndrome and focus first on treating the causative condition while simultaneously attempting symptomatic treatment of catatonia.}, year = {2016}, pages = {110-114}, orcid-numbers = {Faludi, Gábor/0000-0002-1117-0510; Gazdag Gábor, László/0000-0002-6914-8041} } @article{MTMT:3084398, title = {Schizophrenia causes significant burden to patients' and caregivers' lives}, url = {https://m2.mtmt.hu/api/publication/3084398}, author = {Szkultecka-Debek, M and Miernik, K and Stelmachowski, J and Jakovljevic, M and Jukic, V and Aadamsoo, K and Janno, S and Bitter, István and Tolna, Judit and Jarema, M and Jankovic, S and Pecenak, J and Vavrusova, L and Tavcar, R and Walczak, J and Talbot, D and Augustynska, J}, journal-iso = {PSYCHIAT DANUB}, journal = {PSYCHIATRIA DANUBINA}, volume = {28}, unique-id = {3084398}, issn = {0353-5053}, abstract = {BACKGROUND: Schizophrenia is a serious public health problem and is ranked among the most disabling diseases in the world. The sub-study presented here was part of a larger project to characterize the burden of schizophrenia on healthcare systems and on individuals living with the disease in Central and Eastern Europe (CEE). AIMS: This sub-study aimed to assess and analyze the impact of schizophrenia on many aspects of the lives of patients and caregivers. METHODS: Psychiatrists from selected centers in seven Central and Eastern European countries were asked to complete a questionnaire in order to collect information about the disease history, characteristics, treatment protocols and resources used for each randomly selected patient. All data were statistically analyzed and compared between countries. RESULTS: Data from 961 patients with schizophrenia (mean age 40.7 years, 45.1% female) were included in the analysis. The mean number of days spent in hospital per patient per year across all seven countries was 25.3 days. Hospitalization occurred on average once per year, with psychiatrist visits 9.4 times per year. Of the patients in the study, 61% were single, 12% divorced and 22% married or cohabiting. Almost 84% were living with relatives or a partner; only 17% lived alone and, on average, 25% of patients received support from social workers. Relatives provided care for approximately 60% of patients and 4% of them had to stop working in order to do so. Twenty-nine percent of the patients were unemployed, and 56% received a disability pension or were retired, with only 19% in full-time employment or education. CONCLUSION: Schizophrenia has a significant effect on the lives of patients and caregivers and impacts their social integration.}, year = {2016}, eissn = {1849-0867}, pages = {104-110}, orcid-numbers = {Bitter, István/0000-0002-9464-4709; Tolna, Judit/0000-0002-2358-7292} } @article{MTMT:3071718, title = {Pszichogén nem epilepsziás rosszullétek a klinikai gyakorlatban [Psychogenic nonepileptic seizures: Overview and implications for practice]}, url = {https://m2.mtmt.hu/api/publication/3071718}, author = {Szita, Bernadett and Hidasi, Zoltán}, doi = {10.1556/650.2016.30428}, journal-iso = {ORV HETIL}, journal = {ORVOSI HETILAP}, volume = {157}, unique-id = {3071718}, issn = {0030-6002}, abstract = {Psychogenic nonepileptic seizures are enigmatic disorders at the interface of neurology and psychiatry. Seizures resemble epileptic seizures but are not associated with electrical discharges in the brain. Symptoms typically start in early adulthood and women are far more affected than men. Video-EEG is widely considered to be the gold standard for diagnosis. Still psychogenic nonepileptic seizures are often misdiagnosed and treated as epilepsy for years that is burdensome to patients and costly to the healthcare system. Patients having psychogenic nonepileptic seizures show a high prevalence of traumatic life events, therefore, psychosocial factors are thought to play an important role in the etiology. Neurobiological factors may also contribute to the development of seizures as a subgroup of patients are characterized by cognitive impairment and subtle structural and functional brain abnormalities. Treatment includes psychotherapeutic procedures, particularly cognitive behavioral therapy and additional pharmacological interventions. This article presents an overview of the clinical context, diagnosis, etiology and treatment of psychogenic nonepileptic seizures.}, keywords = {ETIOLOGY; treatment; SEMIOLOGY; video-EEG; Psychogenic nonepileptic seizures}, year = {2016}, eissn = {1788-6120}, pages = {767-775}, orcid-numbers = {Hidasi, Zoltán/0000-0002-7798-0145} } @article{MTMT:3071304, title = {Altered response-preparation in patients with adult ADHD: A high-density ERP study.}, url = {https://m2.mtmt.hu/api/publication/3071304}, author = {Kakuszi, Brigitta and Tombor, László and Papp, Szilvia and Bitter, István and Czobor, Pál}, doi = {10.1016/j.pscychresns.2016.02.008}, journal-iso = {PSYCHIAT RES-NEUROIM}, journal = {PSYCHIATRY RESEARCH-NEUROIMAGING}, volume = {249}, unique-id = {3071304}, issn = {0925-4927}, abstract = {Aberrations in early-developing bottom-up processes, such as stimulus-driven response preparation, are thought to play a critical role in the onset of ADHD, and in its persistence over time. Electrophysiology offers a unique tool to gain insight into response preparation, since response preparation has been associated with distinctive ERP changes, including negative potential-shifts which occur predominantly over frontal brain areas. We examined response-preceding negative potential shifts (RPNS) as a probe of response-preparation in adult ADHD patients by obtaining high-density event-related potentials from 33 ADHD and 29 matched healthy subjects during a Go/Nogo task using a 128-channel BioSemi recording-system. Compared to controls, ADHD patients showed enhancement of the RPNS in fronto-central brain regions in the Go condition during correct responses. This change was associated with poor performance in the Stroop incongruency-task: the greater the enhancement, the higher the proportion of errors. Moreover, the ERP-enhancement showed association with the severity of ADHD-symptoms; and with heightened response-variability. Thus, ADHD patients demonstrate neurophysiological alterations in response-preparation and response-preceding brain activity, suggestive of excessive activation of prefrontal neural circuits. Given the correlation with neuropsychological and psychopathological measures, these changes may constitute a pathway for core symptoms of ADHD, including premature and impaired response-preparation and motor-hyperactivity.}, year = {2016}, eissn = {1872-7506}, pages = {57-66}, orcid-numbers = {Kakuszi, Brigitta/0000-0002-9102-4096; Tombor, László/0000-0001-9410-5732; Papp, Szilvia/0000-0002-6270-6952; Bitter, István/0000-0002-9464-4709; Czobor, Pál/0000-0002-6361-8006} }