@article{MTMT:34779723, title = {Olfactory genes affect major depression in highly educated, emotionally stable, lean women: a bridge between animal models and precision medicine}, url = {https://m2.mtmt.hu/api/publication/34779723}, author = {Eszlári, Nóra and Hullám, Gábor István and Gál, Zsófia and Török, Dóra and Nagy, Tamás and Millinghoffer, András Dániel and Baksa, Dániel and Gonda, Xénia and Antal, Péter and Bagdy, György and Juhász, Gabriella}, doi = {10.1038/s41398-024-02867-2}, journal-iso = {TRANSL PSYCHIAT}, journal = {TRANSLATIONAL PSYCHIATRY}, volume = {14}, unique-id = {34779723}, issn = {2158-3188}, abstract = {Most current approaches to establish subgroups of depressed patients for precision medicine aim to rely on biomarkers that require highly specialized assessment. Our present aim was to stratify participants of the UK Biobank cohort based on three readily measurable common independent risk factors, and to investigate depression genomics in each group to discover common and separate biological etiology. Two-step cluster analysis was run separately in males ( n = 149,879) and females ( n = 174,572), with neuroticism (a tendency to experience negative emotions), body fat percentage, and years spent in education as input variables. Genome-wide association analyses were implemented within each of the resulting clusters, for the lifetime occurrence of either a depressive episode or recurrent depressive disorder as the outcome. Variant-based, gene-based, gene set-based, and tissue-specific gene expression test were applied. Phenotypically distinct clusters with high genetic intercorrelations in depression genomics were found. A two-cluster solution was the best model in each sex with some differences including the less important role of neuroticism in males. In females, in case of a protective pattern of low neuroticism, low body fat percentage, and high level of education, depression was associated with pathways related to olfactory function. While also in females but in a risk pattern of high neuroticism, high body fat percentage, and less years spent in education, depression showed association with complement system genes. Our results, on one hand, indicate that alteration of olfactory pathways, that can be paralleled to the well-known rodent depression models of olfactory bulbectomy, might be a novel target towards precision psychiatry in females with less other risk factors for depression. On the other hand, our results in multi-risk females may provide a special case of immunometabolic depression.}, year = {2024}, eissn = {2158-3188}, orcid-numbers = {Eszlári, Nóra/0000-0003-4913-028X; Hullám, Gábor István/0000-0002-4765-2351; Gál, Zsófia/0000-0002-9441-1497; Török, Dóra/0000-0001-9213-4345; Nagy, Tamás/0000-0002-0137-4341; Baksa, Dániel/0000-0002-7826-9179; Gonda, Xénia/0000-0001-9015-4203; Bagdy, György/0000-0001-8141-3410; Juhász, Gabriella/0000-0002-5975-4267} } @article{MTMT:34752694, title = {The relationship between alexithymia, rumination and binge drinking among university students}, url = {https://m2.mtmt.hu/api/publication/34752694}, author = {Alpay, Pelin and Kocsel, Natália and Galambos, Attila and Kökönyei, Gyöngyi}, doi = {10.1016/j.paid.2024.112621}, journal-iso = {PERS INDIV DIFFER}, journal = {PERSONALITY AND INDIVIDUAL DIFFERENCES}, volume = {223}, unique-id = {34752694}, issn = {0191-8869}, year = {2024}, eissn = {1873-3549}, orcid-numbers = {Kökönyei, Gyöngyi/0000-0001-6750-2644} } @article{MTMT:34740737, title = {Reconceptualising depression along the endogenuous-reactive spectrum: GWAS shows involvement of different genes in depression depending on presence vs absence of exposure to stress. SP40.02}, url = {https://m2.mtmt.hu/api/publication/34740737}, author = {Gonda, Xénia}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740737}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203} } @article{MTMT:34740442, title = {Larks under pressure: The genetic background of the morning chronotype may contribute to depression in interaction with stress. EPV0407}, url = {https://m2.mtmt.hu/api/publication/34740442}, author = {Csikos, Mate and Krause, Sándor and Gal, Zsofia and Bagdy, Gyorgy and Juhasz, Gabriella. and Gonda, Xénia and Torok, Dora}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740442}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Krause, Sándor/0000-0002-1953-4980; Gonda, Xénia/0000-0001-9015-4203} } @article{MTMT:34740426, title = {Psychological understanding of Anorexia nervosa gained from combined clinical care. EPV0455}, url = {https://m2.mtmt.hu/api/publication/34740426}, author = {Biliczki, Judit and Bognár, Judit and B. Pólya, Dorottya and Somogyi, Szilvia and Sutori, Sára and Gonda, Xénia and Hamvas, Szilárd and Réthelyi, János}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740426}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203} } @article{MTMT:34740415, title = {Multidimensional assessment of personality disorders using different theoretical models: a comparison of the Young Schema Questionnaire, the SCID-5-AMPD structured diagnostic interview, and the PDS-ICD-11 self-report questionnaire. EPP0024}, url = {https://m2.mtmt.hu/api/publication/34740415}, author = {Pribula, Viktoria and Kiraly, Lilien and Biliczki, Judit and Pongracz, Fanni and Ruscsak, Peter and B. Vadon, Nikolett and Erdelyi- Hamza, Berta and A. Renko, Tamara and Szocs, Henrietta and Vizin, Gabriella and Gonda, Xénia}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740415}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203} } @article{MTMT:34740399, title = {GWAS in interaction with childhood traumas implicates novel variants and genes previously associated with suiciderelated factors in the background of suicidal ideation. EPP0586}, url = {https://m2.mtmt.hu/api/publication/34740399}, author = {Gonda, Xénia and Krause, Sándor and Erdelyi-Hamza, Berta and Sutori, Sara and Gal, Zsofia and Eszlari, Nora and Bagdy, Gyorgy and Juhasz, Gabriella and Torok, Dora}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740399}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Gonda, Xénia/0000-0001-9015-4203; Krause, Sándor/0000-0002-1953-4980} } @article{MTMT:34740391, title = {Mental health competencies are stronger determinants of well-being than mental disorder symptoms even in psychiatric samples}, url = {https://m2.mtmt.hu/api/publication/34740391}, author = {Zábó, Virág and Erát, Dávid and Vargha, András and Harangozó, Judit and Iváncsics, Máté László and Vincze, Ágnes and Farkas, Judit and Balogh, Gábor and Cowden, Richard and Pongrácz, Fanni and Bognár, Judit and Nagy, Enikő and Purebl, György and Gonda, Xénia}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740391}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Erát, Dávid/0000-0001-9681-2713; Iváncsics, Máté László/0009-0004-5122-2436; Vincze, Ágnes/0000-0002-3433-3722; Purebl, György/0000-0002-9750-2001; Gonda, Xénia/0000-0001-9015-4203} } @article{MTMT:34740378, title = {Psychological immunity: A new mental health test for psychiatric samples. EPP0053}, url = {https://m2.mtmt.hu/api/publication/34740378}, author = {Zábó, Virág and Erát, Dávid and Gonda, Xénia and Harangozó, Judit and Iváncsics, Máté László and Vincze, Ágnes and Farkas, Judit and Balogh, Gábor and Cowden, Richard and Oláh, Attila and Kéri, Szabolcs and Purebl, György and Vargha, András}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740378}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Erát, Dávid/0000-0001-9681-2713; Gonda, Xénia/0000-0001-9015-4203; Iváncsics, Máté László/0009-0004-5122-2436; Vincze, Ágnes/0000-0002-3433-3722; Kéri, Szabolcs/0000-0001-7638-1741; Purebl, György/0000-0002-9750-2001} } @article{MTMT:34740356, title = {Dominant depressive, anxious and cyclothymic affective temperaments lower the chance of infertility treatment success. EPV1127}, url = {https://m2.mtmt.hu/api/publication/34740356}, author = {Szabó, Georgina Irén and Szigeti F., Judit and Sipos, Miklos and Varbiro, Szabolcs and Gonda, Xénia}, journal-iso = {EUR PSYCHIAT}, journal = {EUROPEAN PSYCHIATRY}, unique-id = {34740356}, issn = {0924-9338}, year = {2024}, eissn = {1778-3585}, orcid-numbers = {Szabó, Georgina Irén/0000-0001-6809-9674; Gonda, Xénia/0000-0001-9015-4203} }