TY - GEN AU - Gera, János AU - Fülöp, Lívia AU - Paragi, Gábor TI - Pontmutációk hatása az amiloid béta monomer konformációs terére PY - 2018 UR - https://m2.mtmt.hu/api/publication/31624656 ID - 31624656 LA - Hungarian DB - MTMT ER - TY - GEN AU - Bogár, Ferenc AU - Fülöp, Lívia AU - Penke, Botond TI - Szigma-1 receptor ligandumok kötődésének molekuladinamikai vizsgálata PY - 2018 UR - https://m2.mtmt.hu/api/publication/31624655 ID - 31624655 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Masa, Roland AU - Imre-Deák, Ágota AU - Braunitzer, Gábor AU - Tóth, Zsolt AU - Heszlerné Kopniczky, Judit AU - Pelsőczi-Kovács, István AU - Ungvári, Krisztina AU - Dékány, Imre AU - Turzó, Kinga Mónika TI - TiO2/Ag–TiO2 Nanohybrid Films are Cytocompatible with Primary Epithelial Cells of Human Origin: An In Vitro Study JF - JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY J2 - J NANOSCI NANOTECHNO VL - 18 PY - 2018 IS - 6 SP - 3916 EP - 3924 PG - 9 SN - 1533-4880 DO - 10.1166/jnn.2018.15261 UR - https://m2.mtmt.hu/api/publication/3301587 ID - 3301587 N1 - Összes idézések száma a WoS-ban: 0 LA - English DB - MTMT ER - TY - CONF AU - Kálomista, Ildikó AU - Kéri, Albert AU - Ungor, Ditta Anita AU - Csapó, Edit AU - Dékány, Imre AU - Galbács, Gábor ED - Corozzi, Alessandro TI - Extending the applicability of the single particle ICP-MS technique to the investigation of nanorods and nanoalloys T2 - Book of abstracts of the 9th Euro-Mediterranean Symposium on LIBS (EMSLIBS) and Colloquium Spectroscopicum Internationale (CSI) XL PB - Asti Incentives & Congressi (AIC) C1 - Pisa PY - 2017 SP - 525 EP - 525 PG - 1 UR - https://m2.mtmt.hu/api/publication/3299783 ID - 3299783 LA - English DB - MTMT ER - TY - JOUR AU - Mándity, István AU - Nekkaa, Imane AU - Paragi, Gábor AU - Fülöp, Ferenc TI - Homochirality of beta-Peptides: A Significant Biomimetic Property of Unnatural Systems JF - CHEMISTRYOPEN J2 - CHEMISTRYOPEN VL - 6 PY - 2017 IS - 4 SP - 492 EP - 496 PG - 5 SN - 2191-1363 DO - 10.1002/open.201700078 UR - https://m2.mtmt.hu/api/publication/3266869 ID - 3266869 AB - Homochirality, an interesting phenomenon of life, is mainly an unresolved problem and was thought to be a property of living matter. Herein, we show that artificial beta-peptides have the tendency toward homochiral diastereoselective chain elongation. Chain-length-dependent stereochemical discrimination was investigated in the synthesis of foldamers with various side chains and secondary structures. It was found that there is a strong tendency toward the synthesis of homochiral oligomers. The size of the side chain drastically influenced the selectivity of the stereodiscriminative chain-elongation reaction. It is noteworthy that water as the co-solvent increases the selectivity. Such behavior is a novel fundamental biomimetic property of foldamers with a potential of future industrial application. LA - English DB - MTMT ER - TY - JOUR AU - Csapó, Edit AU - Ungor, Ditta Anita AU - Kele, Zoltán AU - Baranyai, Péter AU - Deák, Andrea Beáta AU - Juhász, Ádám AU - Janovák, László AU - Dékány, Imre TI - Influence of pH and aurate/amino acid ratios on the tuneable optical features of gold nanoparticles and nanoclusters JF - COLLOIDS AND SURFACES A : PHYSICOCHEMICAL AND ENGINEERING ASPECTS J2 - COLLOID SURFACE A VL - 532 PY - 2017 IS - 5 SP - 601 EP - 608 PG - 8 SN - 0927-7757 DO - 10.1016/j.colsurfa.2017.02.047 UR - https://m2.mtmt.hu/api/publication/3257484 ID - 3257484 N1 - MTA-SZTE Supramolecular and Nanostructured Materials Research Group, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Department of Physical Chemistry and Materials Sciences, University of Szeged, Aradi v.t.1, Szeged, H-6720, Hungary Department of Medical Chemistry, Faculty of Medicine, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Hungarian Academy of Sciences, MTA TTK SZKI Lendület Supramolecular Chemistry Research Group, Magyar tudósok körútja 2, Budapest, H-1117, Hungary Cited By :17 Export Date: 6 September 2023 CODEN: CPEAE Correspondence Address: Csapó, E.; MTA-SZTE Supramolecular and Nanostructured Materials Research Group, Dóm tér 8, Hungary; email: tidecs2000@yahoo.co.uk AB - Blue-and green-emitting gold nanostructures have been synthesized by spontaneous interactions ofthe tetrachloroaurate anions (AuCl4-) withL-histidine (His) and L-tryptophan (Trp) at 37 degrees C in aqueousmedium. The dominant role of AuCl4-/amino acid molar ratios as well as the pH in the formation ofgold nanoparticles (Au NPs) or nanoclusters (Au NCs) was confirmed by numerous spectroscopic techniques. We demonstrate that without additional reducing agents the His and Trp show different reductionbehaviour with AuCl4-which supports the fact that the unique optical features originate from diversestructures. Because of the pH-dependent complexation and reduction capability of the studied aminoacids the dominant presence of polynuclear fluorescent gold(I) complexes (quantum yield (QY%) similar to 4%) with a well-ordered structure is presumable for His-directed Au system confirmed by mass spectrometry, X-ray diffraction and infrared experiments. The existence of d = 8 nm-sized Au NPs or subnanometer-sized(d < 2 nm) Au NCs (Au3-Au5) that have tuneable blue or green photoluminescence (lambda(emission)= 470-500 nm) was identified in the samples containing Trp depending on the applied AuCl4-/Trp ratios. The blueemitting Au/His nanohybrid system as potential bioimaging agent was used to visualize fluorescentlyalbuminand chitosan-based carrier composite particles. (C) 2017 Elsevier B. V. All rights reserved. LA - English DB - MTMT ER - TY - JOUR AU - Janovák, László AU - Imre-Deák, Ágota AU - Tallósy, Szabolcs Péter AU - Sebők, Dániel AU - Csapó, Edit AU - Bohinc, K AU - Abram, A AU - Pálinkó, István AU - Dékány, Imre TI - Hydroxyapatite-enhanced structural, photocatalytic and antibacterial properties of photoreactive TiO2/HAp/polyacrylate hybrid thin films JF - SURFACE AND COATINGS TECHNOLOGY J2 - SURF COAT TECH VL - 326 PY - 2017 SP - 316 EP - 326 PG - 11 SN - 0257-8972 DO - 10.1016/j.surfcoat.2017.07.072 UR - https://m2.mtmt.hu/api/publication/3252197 ID - 3252197 N1 - Megjegyzés-27479479 N1 Funding details: MTA, Magyar Tudományos Akadémia N1 Funding details: OTKA) K 116323, OTKA, Országos Tudományos Kutatási Alapprogramok N1 Funding details: PD 116224, OTKA, Országos Tudományos Kutatási Alapprogramok N1 Funding details: GINOP-2.3.2-15-2016-00013, OTKA, Országos Tudományos Kutatási Alapprogramok N1 Funding text: The authors are very thankful for the financial support from the Hungarian Scientific Research Fund (OTKA) K 116323, NK 106234, PD 116224 and the project named GINOP-2.3.2-15-2016-00013. This paper was supported by the J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences. Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich B. tér 1, Szeged, H-6720, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, Ljubljana, 1000, Slovenia Department for Nanostructured Materials, ‘Jožef Stefan’ Institute, Jamova cesta 39, Ljubljana, 1000, Slovenia Jožef Stefan International Postgraduate School, Jamova cesta 39, Ljubljana, 1000, Slovenia Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Cited By :8 Export Date: 28 August 2020 Correspondence Address: Janovák, L.; Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich B. tér 1, Hungary; email: janovakl@chem.u-szeged.hu Funding details: Hungarian Scientific Research Fund, OTKA Funding details: Magyar Tudományos Akadémia, MTA Funding details: Hungarian Scientific Research Fund, OTKA, PD 116224, K 116323, NK 106234, GINOP-2.3.2-15-2016-00013 Funding text 1: The authors are very thankful for the financial support from the Hungarian Scientific Research Fund (OTKA) K 116323, NK 106234, PD 116224 and the project named GINOP-2.3.2-15-2016-00013. This paper was supported by the J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences. Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich B. tér 1, Szeged, H-6720, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, Ljubljana, 1000, Slovenia Department for Nanostructured Materials, ‘Jožef Stefan’ Institute, Jamova cesta 39, Ljubljana, 1000, Slovenia Jožef Stefan International Postgraduate School, Jamova cesta 39, Ljubljana, 1000, Slovenia Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Cited By :11 Export Date: 10 January 2021 Correspondence Address: Janovák, L.; Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich B. tér 1, Hungary; email: janovakl@chem.u-szeged.hu Funding details: Magyar Tudományos Akadémia, MTA Funding details: Hungarian Scientific Research Fund, OTKA Funding details: Hungarian Scientific Research Fund, OTKA, PD 116224, K 116323, NK 106234, GINOP-2.3.2-15-2016-00013 Funding text 1: The authors are very thankful for the financial support from the Hungarian Scientific Research Fund (OTKA) K 116323, NK 106234, PD 116224 and the project named GINOP-2.3.2-15-2016-00013. This paper was supported by the J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences. Department of Physical Chemistry and Materials Science, University of Szeged, Rerrich B. tér 1, Szeged, H-6720, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Faculty of Health Sciences, University of Ljubljana, Zdravstvena pot 5, Ljubljana, 1000, Slovenia Department for Nanostructured Materials, ‘Jožef Stefan’ Institute, Jamova cesta 39, Ljubljana, 1000, Slovenia Jožef Stefan International Postgraduate School, Jamova cesta 39, Ljubljana, 1000, Slovenia Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, H-6720, Hungary Cited By :11 Export Date: 10 March 2021 Correspondence Address: Janovák, L.; Department of Physical Chemistry and Materials Science, Rerrich B. tér 1, Hungary; email: janovakl@chem.u-szeged.hu Funding details: Hungarian Scientific Research Fund, OTKA, GINOP-2.3.2-15-2016-00013, K 116323, NK 106234, PD 116224 Funding details: Magyar Tudományos Akadémia, MTA Funding text 1: The authors are very thankful for the financial support from the Hungarian Scientific Research Fund (OTKA) K 116323, NK 106234, PD 116224 and the project named GINOP-2.3.2-15-2016-00013. This paper was supported by the J?nos Bolyai Research Scholarship of the Hungarian Academy of Sciences. LA - English DB - MTMT ER - TY - JOUR AU - Ungor, Ditta Anita AU - Csapó, Edit AU - Kismárton, Barbara AU - Juhász, Ádám AU - Dékány, Imre TI - Nucleotide-directed syntheses of gold nanohybrid systems with structure-dependent optical features: Selective fluorescence sensing of Fe3+ ions JF - COLLOIDS AND SURFACES B: BIOINTERFACES J2 - COLLOID SURFACE B VL - 155 PY - 2017 SP - 135 EP - 141 PG - 7 SN - 0927-7765 DO - 10.1016/j.colsurfb.2017.04.013 UR - https://m2.mtmt.hu/api/publication/3212724 ID - 3212724 AB - Abstract This study demonstrates a one-step synthesis for the preparation of both adenosine monophosphate (AMP)-stabilized colloidal gold nanoparticles (AMP-Au NPs) and fluorescent gold nanoclusters (AMP-Au NCs). The dominant role of AMP:AuCl4− molar ratios in the formation of diverse nanosized Au products was proved. The size, the structure and the unique structure-dependent optical properties of the NPs and NCs were determined based on the results of numerous spectroscopic (UV–vis, fluorescence, infrared, x-ray photoelectron), high resolution electron microscopy (HRTEM) and dynamic light scattering (DLS) techniques. Stabile AMP-Au NPs with diameter of ca. 11 nm and ultra-small AMP-Au NCs having blue fluorescence (λem = 480 nm) were identified. In addition, the AMP-Au NCs have been utilized to develop a selective sensor for the detection of Fe3+ ions in aqueous medium based on fluorescence quenching. Several essential metal ions and anions have been tested but our results clearly supported that dominant quenching was observed only for Fe3+ ions. Based on the determined limit of detection (LOD = 2.0 μM) our system is capable of detecting Fe3+ ions in drinking water. The Stern-Volmer constants (KSV) and various thermodynamic parameters (ΔG, ΔH°, ΔS°, ΔCp) of the quenching process have also been determined by the Stern-Volmer fitting of the fluorescence data in order to better understand the quenching mechanism. LA - English DB - MTMT ER - TY - JOUR AU - Mihalik, Balázs AU - Pálvölgyi, Adrienn AU - Bogár, Ferenc AU - Megyeri, Katalin AU - Ling, István AU - Barkóczy, József AU - Bartha, Ferenc AU - Martinek, Tamás AU - Gacsályi, István AU - Antoni, Ferenc András TI - Loop-F of the alpha-subunit determines the pharmacologic profile of novel competitive inhibitors of GABA(A) receptors JF - EUROPEAN JOURNAL OF PHARMACOLOGY J2 - EUR J PHARMACOL VL - 798 PY - 2017 SP - 129 EP - 136 PG - 8 SN - 0014-2999 DO - 10.1016/j.ejphar.2017.01.033 UR - https://m2.mtmt.hu/api/publication/3193426 ID - 3193426 N1 - Funding Agency and Grant Number: Lendulet (Momentum) program of the Hungarian Academy of Sciences\n Funding text: With the exception of FBc, FBd and TM all authors were employees of Egis Pharmaceuticals PLC, Budapest, Hungary. The work of TM is supported by the Lendulet (Momentum) program of the Hungarian Academy of Sciences. We thank Dr. Patricia Machado (Les Laboratoires Servier, Suresnes, France) for helpful comments on the manuscript.\n Division of Preclinical Research, Egis Pharmaceuticals PLC, Hungary Chemical Research Division, Egis Pharmaceuticals PLC, Budapest, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group of HAS, University of Szeged, Hungary Department of Medical Chemistry, University of Szeged, Hungary Institute of Pharmaceutical Analysis, SZTE-MTA Lendület Foldamer Research Group, University of Szeged, Szeged, Hungary Cited By :5 Export Date: 22 May 2020 CODEN: EJPHA Correspondence Address: Antoni, F.A.Hungary; email: franzantoni@gmail.com Chemicals/CAS: bicuculline, 485-49-4; etomidate, 15301-65-2, 33125-97-2, 51919-80-3; 4 aminobutyric acid, 28805-76-7, 56-12-2; Benzodiazepines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Oxazoles; Protein Subunits; Receptors, GABA-A Division of Preclinical Research, Egis Pharmaceuticals PLC, Hungary Chemical Research Division, Egis Pharmaceuticals PLC, Budapest, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group of HAS, University of Szeged, Hungary Department of Medical Chemistry, University of Szeged, Hungary Institute of Pharmaceutical Analysis, SZTE-MTA Lendület Foldamer Research Group, University of Szeged, Szeged, Hungary Cited By :5 Export Date: 1 January 2021 CODEN: EJPHA Correspondence Address: Antoni, F.A.Hungary; email: franzantoni@gmail.com Chemicals/CAS: bicuculline, 485-49-4; etomidate, 15301-65-2, 33125-97-2, 51919-80-3; 4 aminobutyric acid, 28805-76-7, 56-12-2; Benzodiazepines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Oxazoles; Protein Subunits; Receptors, GABA-A Division of Preclinical Research, Egis Pharmaceuticals PLC, Hungary Chemical Research Division, Egis Pharmaceuticals PLC, Budapest, Hungary MTA-SZTE Supramolecular and Nanostructured Materials Research Group of HAS, University of Szeged, Hungary Department of Medical Chemistry, University of Szeged, Hungary Institute of Pharmaceutical Analysis, SZTE-MTA Lendület Foldamer Research Group, University of Szeged, Szeged, Hungary Cited By :5 Export Date: 31 May 2021 CODEN: EJPHA Correspondence Address: Antoni, F.A.Hungary; email: franzantoni@gmail.com Chemicals/CAS: bicuculline, 485-49-4; etomidate, 15301-65-2, 33125-97-2, 51919-80-3; 4 aminobutyric acid, 28805-76-7, 56-12-2; Benzodiazepines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Oxazoles; Protein Subunits; Receptors, GABA-A LA - English DB - MTMT ER - TY - JOUR AU - Juhász, Ádám AU - Csapó, Edit AU - Vécsei, László AU - Dékány, Imre TI - Modelling and Characterization of the Sorption of Kynurenic Acid on Protein Surfaces JF - PERIODICA POLYTECHNICA-CHEMICAL ENGINEERING J2 - PERIOD POLYTECH CHEM ENG VL - 61 PY - 2017 IS - 1 SP - 3 EP - 9 PG - 7 SN - 0324-5853 DO - 10.3311/PPch.10185 UR - https://m2.mtmt.hu/api/publication/3181824 ID - 3181824 LA - English DB - MTMT ER -