@inproceedings{MTMT:247717, title = {Mechanism of Neurodegeneration and Neuroprotection}, url = {https://m2.mtmt.hu/api/publication/247717}, author = {Penke, Botond and Datki, Zsolt László and Soós, Katalin and Zarándi, Márta}, booktitle = {Biologically Active Peptides : XIIth Conference, Collection Symposium Series}, unique-id = {247717}, year = {2011}, pages = {81-85}, orcid-numbers = {Penke, Botond/0000-0003-0938-0567; Datki, Zsolt László/0000-0002-2537-4741; Zarándi, Márta/0000-0002-2136-2946} } @article{MTMT:246981, title = {A krónikus agyi hipoperfúzió szerepe az Alzheimer-kór kialakulásában--tények és hipotézisek [The role of chronic brain hypoperfusion in the pathogenesis of Alzheimer's disease--facts and hypotheses]}, url = {https://m2.mtmt.hu/api/publication/246981}, author = {Zádori, Dénes and Datki, Zsolt László and Penke, Botond}, journal-iso = {IDEGGYOGY SZEMLE}, journal = {IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE}, volume = {60}, unique-id = {246981}, issn = {0019-1442}, year = {2007}, eissn = {2498-6208}, pages = {428-437}, orcid-numbers = {Zádori, Dénes/0000-0003-0749-7980; Datki, Zsolt László/0000-0002-2537-4741; Penke, Botond/0000-0003-0938-0567} } @article{MTMT:1329879, title = {Single Diastereomers of Polyhydroxylated 9-Oxa-1-azabicyclo[4.2.1]nonanes from Intramolecular 1,3-Dipolar Cycloaddition of ω-Unsaturated Nitrones}, url = {https://m2.mtmt.hu/api/publication/1329879}, author = {Pádár, Petra and Bokros, Attila and Paragi, Gábor and Forgó, Péter and Kele, Zoltán and Howarth, Nicola M and Kovács, Lajos}, doi = {10.1021/jo061503b}, journal-iso = {J ORG CHEM}, journal = {JOURNAL OF ORGANIC CHEMISTRY}, volume = {71}, unique-id = {1329879}, issn = {0022-3263}, year = {2006}, eissn = {1520-6904}, pages = {8669-8672}, orcid-numbers = {Paragi, Gábor/0000-0001-5408-1748; Forgó, Péter/0000-0002-0279-6896; Kele, Zoltán/0000-0002-4401-0302; Kovács, Lajos/0000-0002-0331-3980} } @article{MTMT:1070570, title = {Self-assembly of Alzheimer's disease-related amyloid peptides into highly ordered nanostructures}, url = {https://m2.mtmt.hu/api/publication/1070570}, author = {Fülöp, Lívia and Zarándi, Márta and Soós, Katalin and Penke, Botond}, doi = {10.1556/NANO.1.2006.1.3}, journal-iso = {NANOPAGES}, journal = {NANOPAGES}, volume = {1}, unique-id = {1070570}, issn = {1787-4033}, year = {2006}, eissn = {1788-0718}, pages = {69-83}, orcid-numbers = {Fülöp, Lívia/0000-0002-8010-0129; Zarándi, Márta/0000-0002-2136-2946; Penke, Botond/0000-0003-0938-0567} } @article{MTMT:1008544, title = {Combination of a modified scoring function with two-dimensional descriptors for calculation of binding affinities of bulky, flexible ligands to proteins}, url = {https://m2.mtmt.hu/api/publication/1008544}, author = {Hetényi, Csaba and Paragi, Gábor and Maran, U and Timár, Zoltán and Karelson, M and Penke, Botond}, doi = {10.1021/ja055804z}, journal-iso = {J AM CHEM SOC}, journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY}, volume = {128}, unique-id = {1008544}, issn = {0002-7863}, year = {2006}, eissn = {1520-5126}, pages = {1233-1239}, orcid-numbers = {Paragi, Gábor/0000-0001-5408-1748; Penke, Botond/0000-0003-0938-0567} } @article{MTMT:247670, title = {Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice}, url = {https://m2.mtmt.hu/api/publication/247670}, author = {Oksman, M and Livonen, H and Hogyes, E and Amtul, Z and Penke, Botond and Leenders, I and Broersen, L and Lutjohann, D and Hartmann, T and Tanila, H}, doi = {10.1016/j.nbd.2006.04.013}, journal-iso = {NEUROBIOL DIS}, journal = {NEUROBIOLOGY OF DISEASE}, volume = {23}, unique-id = {247670}, issn = {0969-9961}, year = {2006}, eissn = {1095-953X}, pages = {563-572}, orcid-numbers = {Penke, Botond/0000-0003-0938-0567} } @article{MTMT:247668, title = {Folded and unfolded conformations of the omega-3 polyunsaturated fatty acid family: CH3CH2[CH=CHCH2](B)[CH2](M)COOH. First principles study}, url = {https://m2.mtmt.hu/api/publication/247668}, author = {Law, JMS and Szőri, Milán and Izsak, R and Penke, Botond and Csizmadia, Imre Gyula and Viskolcz, Béla}, doi = {10.1021/jp058215o}, journal-iso = {J PHYS CHEM A}, journal = {JOURNAL OF PHYSICAL CHEMISTRY A}, volume = {110}, unique-id = {247668}, issn = {1089-5639}, keywords = {CLASSIFICATION; ARTICLE; CONFORMATION; Chemistry; Models, Biological; Mathematical models; computer simulation; Molecular Conformation; THERMODYNAMICS; fatty acids; biological model; molecular structure; chemical structure; ISOMERIZATION; Carboxylic acids; Fatty Acids, Omega-3; Thermodynamic properties; omega 3 fatty acid; Polymeric membranes; Thermodynamic function; Polyunsaturated fatty acids (PUFA); Chain fragment models}, year = {2006}, eissn = {1520-5215}, pages = {6100-6111}, orcid-numbers = {Szőri, Milán/0000-0003-4895-0999; Penke, Botond/0000-0003-0938-0567} } @article{MTMT:247664, title = {Density functional crystal orbital study of cyano-substituted poly(para-phenylene-vinylene) and poly(quinoxaline-vinylene)}, url = {https://m2.mtmt.hu/api/publication/247664}, author = {Bartha, Ferenc and Howard, IA and Geerlings, P and Van, Alsenoy C and Vanderzande, D and Cleij, TJ and Bogár, Ferenc}, doi = {10.1002/qua.20937}, journal-iso = {INT J QUANTUM CHEM}, journal = {INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY}, volume = {106}, unique-id = {247664}, issn = {0020-7608}, year = {2006}, eissn = {1097-461X}, pages = {1912-1923}, orcid-numbers = {Bogár, Ferenc/0000-0002-0611-1452} } @article{MTMT:246979, title = {Polypeptide and protein aggregates with neurotoxic properties in neurodegenerative disorders: Emphasis on beta-amyloid-induced dysfunction of receptor-mediated signal transduction pathways}, url = {https://m2.mtmt.hu/api/publication/246979}, author = {Verdier, Y and Penke, Botond}, doi = {10.2174/157436206775269208}, journal-iso = {CURR SIGNAL TRANSDUCT THER}, journal = {CURRENT SIGNAL TRANSDUCTION THERAPY}, volume = {1}, unique-id = {246979}, issn = {1574-3624}, abstract = {Polypeptides and proteins may undergo misfolding processes resulting in aggregates: oligomers and fibrils possessing toxic properties. In most cases a beta-structure will be formed with high tendency to form suprachemical structures, assemblies. The aggregation grade might play crucial role in the biological activities of protein assemblies. Protein aggregates bind to receptors or receptor complexes of neuronal and glial cells and activate signal transduction pathways. Beta amyloid may interact with Writ receptors as well as increases the intracellular Ca-ion level in neurons. GSK-3beta activation causes tau-hyperphosphorylation and collaps of the microtubular system. beta-amyloid triggers also a CD36 dependent signaling cascade and activates microglia. Other misfolded protein assemblies of alpha-synuclein, huntingtin and prion proteins similarly interact with receptor complexes and disturb signal transduction. Rational drug design may start after understanding these signalisation disturbances. Novel drugs will prevent receptor interaction with misfolded protein aggregates.}, year = {2006}, pages = {97-112}, orcid-numbers = {Penke, Botond/0000-0003-0938-0567} } @article{MTMT:140526, title = {The effect of breathing vibration on the charge carrier mobility of a guanine-cytosine base pair stack}, url = {https://m2.mtmt.hu/api/publication/140526}, author = {Beleznay, Ferenc and Szekeres, Z and Bogár, Ferenc and Ladik, J}, doi = {10.1016/j.cplett.2006.04.019}, journal-iso = {CHEM PHYS LETT}, journal = {CHEMICAL PHYSICS LETTERS}, volume = {424}, unique-id = {140526}, issn = {0009-2614}, year = {2006}, eissn = {1873-4448}, pages = {399-402}, orcid-numbers = {Bogár, Ferenc/0000-0002-0611-1452} }