@article{MTMT:34558800,
	title = {The oral microbiome of a family including Papillon-Lefèvre-syndrome patients and clinically healthy members},
	url = {https://m2.mtmt.hu/api/publication/34558800},
	author = {Vályi, Péter and Wirth, Roland and Minárovits, János and Strang, Orsolya and Maróti, Gergely and Kovács, Kornél Lajos},
	doi = {10.1186/s12903-024-03856-z},
	journal-iso = {BMC ORAL HEALTH},
	journal = {BMC ORAL HEALTH},
	volume = {24},
	unique-id = {34558800},
	issn = {1472-6831},
	abstract = {The oral microbiota composition of patients diagnosed with Papillon-Lefèvre-syndrome and treated for several years were compared to those existing in the oral cavity of the clinically healthy family members and a cohort of patients having various stages of chronic periodontitis.},
	year = {2024},
	eissn = {1472-6831},
	orcid-numbers = {Vályi, Péter/0000-0002-9594-2038; Wirth, Roland/0000-0002-2383-2323; Strang, Orsolya/0000-0002-0259-9091; Maróti, Gergely/0000-0002-3705-0461; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:34130955,
	title = {Regulation of the methanogenesis pathways by hydrogen at transcriptomic level in time},
	url = {https://m2.mtmt.hu/api/publication/34130955},
	author = {Szuhaj, Márk and Kakuk, Balázs and Wirth, Roland and Rákhely, Gábor and Kovács, Kornél Lajos and Bagi, Zoltán},
	doi = {10.1007/s00253-023-12700-3},
	journal-iso = {APPL MICROBIOL BIOT},
	journal = {APPLIED MICROBIOLOGY AND BIOTECHNOLOGY},
	volume = {107},
	unique-id = {34130955},
	issn = {0175-7598},
	abstract = {The biomethane formation from 4 H-2 + CO2 by pure cultures of two methanogens, Methanocaldococcus fervens and Methanobacterium thermophilum, has been studied. The goal of the study was to understand the regulation of the enzymatic steps associated with biomethane biosynthesis by H-2, using metagenomic, pan-genomic, and transcriptomic approaches. Methanogenesis in the autotrophic methanogen M. fervens could be easily "switched off" and "switched on" by H-2/CO2 within about an hour. In contrast, the heterotrophic methanogen M. thermophilum was practically insensitive to the addition of the H-2/CO2 trigger although this methanogen also converted H-2/CO2 to CH4. From practical points of view, the regulatory function of H-2/CO2 suggests that in the power-to-gas (P2G) renewable excess electricity conversion and storage systems, the composition of the biomethane-generating methanogenic community is essential for sustainable operation. In addition to managing the specific hydrogenotrophic methanogenesis biochemistry, H-2/CO2 affected several, apparently unrelated, metabolic pathways. The redox-regulated overall biochemistry and symbiotic relationships in the methanogenic communities should be explored in order to make the P2G technology more efficient.},
	keywords = {metabolism; IDENTIFICATION; HYDROGEN; REDUCTION; METHANE; ACETATE; STRAINS; ANAEROBIC-DIGESTION; methanogenesis; Dehydrogenases; Hydrogenotrophic methanogens; Power to gas; THERMOPHILICUM},
	year = {2023},
	eissn = {1432-0614},
	pages = {6315-6324},
	orcid-numbers = {Szuhaj, Márk/0000-0001-7160-3173; Kakuk, Balázs/0000-0002-4314-5707; Wirth, Roland/0000-0002-2383-2323; Rákhely, Gábor/0000-0003-2557-3641; Kovács, Kornél Lajos/0000-0002-3926-0497; Bagi, Zoltán/0000-0001-7795-2024}
}

@article{MTMT:34108330,
	title = {Bioelectrochemical Systems (BES) for Biomethane Production-Review},
	url = {https://m2.mtmt.hu/api/publication/34108330},
	author = {Horváth-Gönczi, Noémi Nikolett and Bagi, Zoltán and Szuhaj, Márk and Rákhely, Gábor and Kovács, Kornél Lajos},
	doi = {10.3390/fermentation9070610},
	journal-iso = {FERMENTATION-BASEL},
	journal = {FERMENTATION},
	volume = {9},
	unique-id = {34108330},
	abstract = {Bioelectrochemical systems (BESs) have great potential in renewable energy production technologies. BES can generate electricity via Microbial Fuel Cell (MFC) or use electric current to synthesize valuable commodities in Microbial Electrolysis Cells (MECs). Various reactor configurations and operational protocols are increasing rapidly, although industrial-scale operation still faces difficulties. This article reviews the recent BES related to literature, with special attention to electrosynthesis and the most promising reactor configurations. We also attempted to clarify the numerous definitions proposed for BESs. The main components of BES are highlighted. Although the comparison of the various fermentation systems is, we collected useful and generally applicable operational parameters to be used for comparative studies. A brief overview links the appropriate microbes to the optimal reactor design.},
	keywords = {CARBON-DIOXIDE; WASTE-WATER TREATMENT; ANAEROBIC-DIGESTION; STAINLESS-STEEL; Biomethane; FUEL-CELL; Microbial electrolysis cell (MEC); Microbial electrolysis cell; Biotechnology & Applied Microbiology; SINGLE-CHAMBER; Ion-exchange membranes; bioelectrochemical system (BES); electro-fermentation; Reactor configurations; ENHANCED METHANE PRODUCTION},
	year = {2023},
	eissn = {2311-5637},
	orcid-numbers = {Bagi, Zoltán/0000-0001-7795-2024; Szuhaj, Márk/0000-0001-7160-3173; Rákhely, Gábor/0000-0003-2557-3641; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:34092103,
	title = {Machine-Learning-Guided Multi-Omics Investigation of Industrial-Scale Biogas Plants Reveals Inter-Kingdom Interactions and Stability of Methanogens},
	url = {https://m2.mtmt.hu/api/publication/34092103},
	author = {Wirth, Roland and Bagi, Z and Shetty, Prateek and Szuhaj, M and Cheung, S and Kovács, Kornél Lajos and Maróti, Gergely},
	journal-iso = {ACTA MICROBIOL IMMUNOL HUNG},
	journal = {ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA},
	volume = {70},
	unique-id = {34092103},
	issn = {1217-8950},
	year = {2023},
	eissn = {1588-2640},
	pages = {87-88},
	orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Kovács, Kornél Lajos/0000-0002-3926-0497; Maróti, Gergely/0000-0002-3705-0461}
}

@article{MTMT:34011308,
	title = {Inter-kingdom interactions and stability of methanogens revealed by machine-learning guided multi-omics analysis of industrial-scale biogas plants},
	url = {https://m2.mtmt.hu/api/publication/34011308},
	author = {Wirth, Roland and Bagi, Zoltán and Shetty, Prateek and Szuhaj, Márk and Cheung, Teur Teur Sally and Kovács, Kornél Lajos and Maróti, Gergely},
	doi = {10.1038/s41396-023-01448-3},
	journal-iso = {ISME J},
	journal = {ISME JOURNAL},
	volume = {17},
	unique-id = {34011308},
	issn = {1751-7362},
	abstract = {Multi-omics analysis is a powerful tool for the detection and study of inter-kingdom interactions, such as those between bacterial and archaeal members of complex biogas-producing microbial communities. In the present study, the microbiomes of three industrial-scale biogas digesters, each fed with different substrates, were analysed using a machine-learning guided genome-centric metagenomics framework complemented with metatranscriptome data. This data permitted us to elucidate the relationship between abundant core methanogenic communities and their syntrophic bacterial partners. In total, we detected 297 high-quality, non-redundant metagenome-assembled genomes (nrMAGs). Moreover, the assembled 16 S rRNA gene profiles of these nrMAGs showed that the phylum Firmicutes possessed the highest copy number, while the representatives of the archaeal domain had the lowest. Further investigation of the three anaerobic microbial communities showed characteristic alterations over time but remained specific to each industrial-scale biogas plant. The relative abundance of various microorganisms as revealed by metagenome data was independent from corresponding metatranscriptome activity data. Archaea showed considerably higher activity than was expected from their abundance. We detected 51 nrMAGs that were present in all three biogas plant microbiomes with different abundances. The core microbiome correlated with the main chemical fermentation parameters, and no individual parameter emerged as a predominant shaper of community composition. Various interspecies H 2 /electron transfer mechanisms were assigned to hydrogenotrophic methanogens in the biogas plants that ran on agricultural biomass and wastewater. Analysis of metatranscriptome data revealed that methanogenesis pathways were the most active of all main metabolic pathways.},
	year = {2023},
	eissn = {1751-7370},
	pages = {1326-1339},
	orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Bagi, Zoltán/0000-0001-7795-2024; Szuhaj, Márk/0000-0001-7160-3173; Cheung, Teur Teur Sally/0009-0007-9541-5231; Kovács, Kornél Lajos/0000-0002-3926-0497; Maróti, Gergely/0000-0002-3705-0461}
}

@article{MTMT:34002270,
	title = {Biohydrogen production through dark fermentation from waste biomass: Current status and future perspectives on biorefinery development},
	url = {https://m2.mtmt.hu/api/publication/34002270},
	author = {D' Silva, Tinku Casper and Khan, Sameer Ahmad and Kumar, Subodh and Kumar, Dushyant and Isha, Adya and Deb, Saptashish and Yadav, Saurabh and Illathukandy, Biju and Chandra, Ram and Vijay, Virendra Kumar and Subbarao, Paruchuri M.V. and Bagi, Zoltán and Kovács, Kornél Lajos and Yu, Liang and Gandhi, Bhushan P. and Semple, Kirk T.},
	doi = {10.1016/j.fuel.2023.128842},
	journal-iso = {FUEL},
	journal = {FUEL},
	volume = {350},
	unique-id = {34002270},
	issn = {0016-2361},
	year = {2023},
	eissn = {1873-7153},
	orcid-numbers = {Bagi, Zoltán/0000-0001-7795-2024; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:33334260,
	title = {Cold-adapted culturing of the microalga Monoraphidium sp. in thin-layer raceway pond for biomass production},
	url = {https://m2.mtmt.hu/api/publication/33334260},
	author = {Lakatos, Gergely Ernő and Ranglová, Karolína and Bárcenas-Pérez, Daniela and Grivalský, Tomáš and Manoel, João Câmara and Mylenko, Mykola and Cheel, José and Nyári, József and Wirth, Roland and Kovács, Kornél Lajos and Kopecký, Jiří and Nedbalová, Linda and Masojídek, Jiří},
	doi = {10.1016/j.algal.2022.102926},
	journal-iso = {ALGAL RES},
	journal = {ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS},
	volume = {69},
	unique-id = {33334260},
	issn = {2211-9264},
	abstract = {Three cultivation regimes were tested in cold-adapted cultures of the green microalga Monoraphidium in an outdoor thin-layer raceway pond: cultivation under sunlight; its combination with continuous supplementary illumination; and nitrogen depletion using both light sources. The highest volumetric and areal productivity, 0.16 g L−1 d−1 and 3.22 g m−2 d−1, respectively corresponding to the specific growth rate μ of 0.191 d−1 were achieved when sunlight was combined with supplementary illumination. The maximum total fatty acid content, 20.29 % of DW, rich in oleic acid, 54 % of total fatty acid content, was achieved under nitrogen depletion stress. An outstanding amount of lutein, 26.39 mg lutein g−1 DW, was detected grown under sunlight in the first trial. From the harvested and fermented biomass in the second trial 236 mLN g−1oTS of methane was generated.},
	year = {2023},
	eissn = {2211-9264},
	orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:33284109,
	title = {Deep learning-guided genome resolved metagenome and metatranscriptome analysis of microbial community in three full-size biogas plants},
	url = {https://m2.mtmt.hu/api/publication/33284109},
	author = {Wirth, Roland and Bagi, Zoltán and Prateek, Shetty and Szuhaj, Márk and Sally, Cheung and Kovács, Kornél Lajos and Maróti, Gergely},
	journal-iso = {ACTA MICROBIOL IMMUNOL HUNG},
	journal = {ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA},
	volume = {70},
	unique-id = {33284109},
	issn = {1217-8950},
	year = {2023},
	eissn = {1588-2640},
	pages = {50-51},
	orcid-numbers = {Wirth, Roland/0000-0002-2383-2323; Bagi, Zoltán/0000-0001-7795-2024; Szuhaj, Márk/0000-0001-7160-3173; Kovács, Kornél Lajos/0000-0002-3926-0497; Maróti, Gergely/0000-0002-3705-0461}
}

@article{MTMT:33189748,
	title = {Pretreatment of lignocellulosic biogas substrates by filamentous fungi},
	url = {https://m2.mtmt.hu/api/publication/33189748},
	author = {Kovács, Etelka and Szűcs, Csilla and Farkas, Attila and Szuhaj, Márk and Maróti, Gergely and Bagi, Zoltán and Rákhely, Gábor and Kovács, Kornél Lajos},
	doi = {10.1016/j.jbiotec.2022.10.013},
	journal-iso = {J BIOTECHNOL},
	journal = {JOURNAL OF BIOTECHNOLOGY},
	volume = {360},
	unique-id = {33189748},
	issn = {0168-1656},
	year = {2022},
	eissn = {1873-4863},
	pages = {160-170},
	orcid-numbers = {Kovács, Etelka/0000-0003-0969-5964; Szuhaj, Márk/0000-0001-7160-3173; Maróti, Gergely/0000-0002-3705-0461; Bagi, Zoltán/0000-0001-7795-2024; Rákhely, Gábor/0000-0003-2557-3641; Kovács, Kornél Lajos/0000-0002-3926-0497}
}

@article{MTMT:33131368,
	title = {Significance of Intermittent Mixing in Mesophilic Anaerobic Digester},
	url = {https://m2.mtmt.hu/api/publication/33131368},
	author = {SINGH, BUTA and Kovács, Kornél Lajos and Bagi, Zoltán and Petrik, Máté and Szepesi L., Gábor and Siménfalvi, Zoltán and Szamosi, Zoltán},
	doi = {10.3390/fermentation8100518},
	journal-iso = {FERMENTATION-BASEL},
	journal = {FERMENTATION},
	volume = {8},
	unique-id = {33131368},
	abstract = {The mixing of slurry in an anaerobic digester (AD) is one of many key parameters, which have a significant effect on specific biogas yield (BY) and volatile solid (VS) removal rate. The determination of the optimum mixing regime in a digester is very complex as it depends on a large number of internal and external factors such as microbial community, the rheology of slurry, digester and impeller design, mixing intensity, and mixing intervals. The novelty of this study is the investigation of the optimum mixing regime in a lab-scale digester under semi-continuous mixing regimes by the continuous monitoring of the physicochemical properties of the digestate. In this study, a helical ribbon (HR) impeller was used for the agitation of the slurry operated at 67 rpm for 5 min under various agitation intervals (1 h, 2 h, 3 h, and 4 h). The results showed a 6–12% reduction in BY as the time between mixing operations increased. The highest BY was observed at a mixing frequency of 5 min/h, which produced a total of 54.1 L of biogas as compared to the mixing frequencies of 2 h, 3 h, and 4 h, where the BYs were recorded as 51.2 L, 49.8 L, and 47.3 L, respectively. Volatile fatty acids (VFAs) and FOS/TAC ratio were stabilized at 5–7 Gl−1 and 0.3–0.5, respectively. The appropriate mixing intensity was determined to obtain the highest biogas production, which could lead to lower power consumption for mixing operations.},
	year = {2022},
	eissn = {2311-5637},
	orcid-numbers = {Kovács, Kornél Lajos/0000-0002-3926-0497; Bagi, Zoltán/0000-0001-7795-2024; Petrik, Máté/0000-0003-0034-464X; Szepesi L., Gábor/0000-0003-0942-374X; Siménfalvi, Zoltán/0000-0003-2641-9638; Szamosi, Zoltán/0000-0002-5494-0212}
}