@article{MTMT:34481386, title = {Translucent monolithic zirconia titanium-supported FP1 full-arch prosthesis: A novel proof of concept to address esthetic, functional, and biologic challenges}, url = {https://m2.mtmt.hu/api/publication/34481386}, author = {Pelekanos, Stavros and Ntovas, Panagiotis and Rizou, Vasiliki and Pozzi, Alessandro}, doi = {10.1111/jerd.13167}, journal-iso = {J ESTHET RESTOR DENT}, journal = {JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY}, volume = {36}, unique-id = {34481386}, issn = {1496-4155}, abstract = {Objective: Despite the wide clinical use of translucent zirconia for full-arch implant prostheses, reduced flexural strength and fracture toughness compared with high-strength opaque zirconia needs to be addressed. A novel proof of concept for FP1 full-arch prosthesis featured by translucent monolithic zirconia and titanium framework was presented. Clinical Considerations: Computer-guided implant planning and surgery were executed and digitally designed FP1 temporary prosthesis prefabricated. Implant and prosthetic placement were achieved with a set of three-dimensional (3D)-printed templates. Implants were immediately loaded. After 4 months intraoral optical scan was taken to record implant coordinates, soft tissue anatomy, and temporary FP1 prosthesis. A novel digital workflow was used to design and mill overlaying translucent zirconia and anatomically shaped titanium framework with a scalloped soft-tissue interface. Final FP1 prosthesis was assembled cementing zirconia jacket on titanium counterpart. Conclusions: Translucent zirconia supported by titanium framework can address esthetic and mechanical requirements of FP1 full-arch prosthesis, minimizing risk of fracture and providing a rigid and passive joint with supporting implants. The smooth and highly polished titanium surface with an anatomic design, tightly matching scalloped soft tissue interface, can limit food impaction, air and saliva leakage and contribute to overall biologic integration of FP1 full-arch prosthesis. Clinical Significance: Translucent monolithic zirconia featured with anatomically shaped titanium framework with scalloped transmucosal part, combining a pleasant esthetic outcome with increased flexural strength and fracture toughness, may be indicated to increase the clinical performance of FP1 full-arch prosthesis.}, keywords = {BRIDGES; Dental prostheses; Immediate loading; Dental implant; IMPLANT PLACEMENT; Digital workflow; Fixed prosthesis; full-arch; FP1; titanium framework}, year = {2024}, eissn = {1708-8240}, pages = {197-206}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:34118614, title = {Accuracy of intraoral optical scan versus stereophotogrammetry for complete-arch digital implant impression: An in vitro study}, url = {https://m2.mtmt.hu/api/publication/34118614}, author = {Pozzi, Alessandro and Agliardi, Enrico and Lio, Fabrizio and Nagy, Katalin and Nardi, Alessandra and Arcuri, Lorenzo}, doi = {10.2186/jpr.JPR_D_22_00251}, journal-iso = {J PROSTHODONT RES}, journal = {JOURNAL OF PROSTHODONTIC RESEARCH}, volume = {68}, unique-id = {34118614}, issn = {1883-1958}, abstract = {To assess and compare the accuracies of intraoral scanners (IOS) and stereophotogrammetry (SPG) devices for complete-arch digital implant impressions.A 4-analog model was digitized using a desk scanner to obtain a reference file. Thirty test scans were conducted using the investigated IOS device, while an additional 30 scans were performed using the SPG device. Using the best-fit algorithm, the resulting 60 test files were aligned with the reference file. Linear (ΔX, ΔY, and ΔZ-axis) and angular deviations (ΔANGLE) were evaluated. Three-dimensional (3D) deviation was calculated based on the Euclidean distance (ΔEUC). The analysis was stratified according to the scanning device and implant position. Fisher's F and t-tests were used to compare the variances and expected values of the two scanning systems.IOS expressed a higher 3D (ΔEUC) mean deviation than SPG (52.8 µm vs. 33.4 µm, P < 0.0001), with extreme measurements up to 181.9 µm. A significantly higher standard deviation (SD) was associated with IOS (37.1 µm vs. 17.7 µm, P < 0.0001). Considering angular deviations, the IOS showed slightly higher angular mean deviations (ΔANGLE) than the SPG (0.28° vs. 0.24°, P = 0.0022), with extreme measurements of up to 0.73°. The SPG SD values were significantly lower than the IOS SD values (0.14° vs. 0.04°, P < 0.0001).The SPG showed significantly higher 3D and angular accuracies for complete arch implant impressions, with consistent repeatability. IOS scanning revealed significantly higher extreme deviations exceeding the acceptable threshold value. Despite study limitations, SPG appears more feasible than IOS for complete-arch digital implant impressions.}, keywords = {stereophotogrammetry; digital impression; intraoral scanner; complete arch}, year = {2024}, eissn = {2212-4632}, pages = {172-180}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186; Nagy, Katalin/0000-0001-9383-5952} } @mastersthesis{MTMT:35089014, title = {The accuracy of stereophotogrammetry for complete-arch digital implant impression in vitro and in vivo}, url = {https://m2.mtmt.hu/api/publication/35089014}, author = {Pozzi, Alessandro}, doi = {10.14232/phd.11917}, publisher = {University of Szeged}, unique-id = {35089014}, year = {2023}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:34118622, title = {Mandibular Flexure and Its Significance: An In Vivo Cone Beam-Computed Tomography Proof-of-Concept Study}, url = {https://m2.mtmt.hu/api/publication/34118622}, author = {Londono, Jimmy and Schoenbaum, Todd R. and Varilla Ortiz, Alma Veronica and Franco-Romero, Guillermo and Villalobos, Vanessa and Carosi, Paolo and Mijiritsky, Eitan and Pozzi, Alessandro}, doi = {10.3390/jcm12124149}, journal-iso = {J CLIN MED}, journal = {JOURNAL OF CLINICAL MEDICINE}, volume = {12}, unique-id = {34118622}, abstract = {The aim of this study was to assess intra-arch mandibular dimensional changes that may occur during mouth opening using cone beam-computed tomography (CBCT). Fifteen patients in need of any type of treatment whose execution considered a pre- and post-CBCT assessment consented and were enrolled. CBCTs were taken with the following settings: 90 kV, 8 mA, field of view (FOV) 140 by 100 mm (height and diameter), Voxel size 0.25 mm (high resolution). The pre-CBCT was executed in the maximum mandibular opening (MO), while the post-CBCT was in the maximum intercuspation (MI). A thermoplastic stent with radiopaque fiducial markers (steel ball bearings) was fabricated for each patient. Measurements were made using radiographic markers between contralateral canines and contralateral first molars and between ipsilateral canines and first molars on both sides. Paired t-tests were performed to evaluate the difference between open and closed positions on these four measurements. In the MO position were registered a significative tightening of the mandible at the canine (-0.49 mm, SD 0.54 mm; p < 0.001) and molar points (-0.81 mm, SD 0.63 mm; p < 0.001) and a significative shortening of the mandible on the right (-0.84 mm, SD 0.80 mm; p < 0.001) and left sides (-0.87 mm, SD 0.49 mm; p < 0.001). Within the study limitations, mandibular flexure determined a significant shortening and tightening between maximum intercuspation to maximum opening positions. Mandibular dimensional changes should be considered in light of other patient factors in the treatment planning of implant positioning and long-span complete arch implant-supported fixed prostheses in order to avoid technical complications.}, keywords = {Dental Implants; CBCT; fixed dental prosthesis; mandibular flexure}, year = {2023}, eissn = {2077-0383}, orcid-numbers = {Carosi, Paolo/0000-0002-2442-1091; Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:34083928, title = {Accuracy of complete-arch digital implant impression with intraoral optical scanning and stereophotogrammetry: An in vivo prospective comparative study}, url = {https://m2.mtmt.hu/api/publication/34083928}, author = {Pozzi, Alessandro and Carosi, P. and Gallucci, G.O. and Nagy, Katalin and Nardi, A. and Arcuri, L.}, doi = {10.1111/clr.14141}, journal-iso = {CLIN ORAL IMPLANTS RES}, journal = {CLINICAL ORAL IMPLANTS RESEARCH}, volume = {34}, unique-id = {34083928}, issn = {0905-7161}, abstract = {Objectives: To assess accuracy of intraoral optical scanning (IOS) and stereophotogrammetry (SPG), complete-arch digital implant impressions in vivo. Materials and Methods: Consecutive patients needing implant-supported screw-retained zirconia complete-arch fixed-dental prostheses (ISZ-FDP) were recruited. For each patient, three impressions were taken: IOS, SPG (tests), and open-tray plaster (reference). Linear (ΔX, ΔY, and ΔZ), three-dimensional (ΔEUC), and angular deviations (ΔANGLE) were evaluated and stratified according to scanning technology for each implant. Potential effects of impression device (IOS and SPG), arch (maxilla and mandible), and implant number (4 and 6) were evaluated through multivariable analysis. Significance level was set at.05. Results: A total of 11 complete arches (5 maxillae, 6 mandibles) in 11 patients were rehabilitated with ISZ-FDPs supported by 4 (n = 8) and 6 implants (n = 3). A total of 50 implants and 100 implant positions were captured by two investigated devices and compared to respective reference (mean ΔEUC IOS 137.2, SPG 87.6 μm; mean ΔANGLE 0.79, 0.38°). Differences between measurements (SPG-IOS) were computed for each implant, with negative values indicating better SPG accuracy. Significant mean ΔEUC difference of −49.60 μm (p =.0143; SD 138.15) and mean ΔANGLE difference of −0.40° (p <.0001; SD 0.65) were observed in favor of SPG. Multivariable analysis showed significant effect on ΔEUC (p =.0162) and ΔANGLE (p =.0001) only for impression devices, with SPG performing better. Conclusions: SPG experienced significantly higher linear and angular accuracy. No effect of type of arch or implant number was detected. Higher extreme deviations were experienced for IOS. SPG can be feasible for complete-arch digital impressions with caution, and rigid prototype try-in is recommended before screw-retained prosthesis manufacturing. © 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.}, keywords = {stereophotogrammetry; Dental implant; digital impression; intraoral scanner; complete arch}, year = {2023}, eissn = {1600-0501}, pages = {1106-1117}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186; Nagy, Katalin/0000-0001-9383-5952} } @article{MTMT:33859091, title = {Long-term survival and success of zirconia screw-retained implant-supported prostheses for up to 12 years: A retrospective multicenter study}, url = {https://m2.mtmt.hu/api/publication/33859091}, author = {Pozzi, Alessandro and Arcuri, L. and Fabbri, G. and Singer, G. and Londono, J.}, doi = {10.1016/j.prosdent.2021.04.026}, journal-iso = {J PROSTHET DENT}, journal = {JOURNAL OF PROSTHETIC DENTISTRY}, volume = {129}, unique-id = {33859091}, issn = {0022-3913}, abstract = {Statement of problem: Despite the broad clinical application of zirconia for fixed implant-supported prostheses, evidence of long-term performance is sparse. Purpose: The purpose of this retrospective study was to evaluate the long-term clinical and radiographic outcomes of zirconia-based partial and complete screw-retained implant-supported zirconia fixed dental prostheses (ISZFDPs). Material and methods: Records of patients treated with dental implants and ISZFDPs between December 2004 and June 2017 were screened. Eligible study participants, according to inclusion criteria, were contacted and invited to undergo clinical and radiographic examinations. Outcomes were evaluated as implant and prosthetic survival rates, prosthetic success rate, complications, marginal bone level (MBL) change, and soft tissue condition. Along with the effects of zirconia prosthesis type and level, the effects of implant type and connection, type of loading, and follow-up on MBL were tested with a generalized linear effects model (GLEM) (α=.05). Results: A total of 118 patients were identified, of whom 20 (16.9%) were not available for clinical examination for various reasons. Ninety-eight participants (mean age 60.7 ±11.7 years) with 337 implants were included, of which 176 (52.2%) had been immediately loaded. A total of 111 ISZFDPs (96 zirconia connection and 15 titanium base) were investigated: 24 complete ISZFDPs with a zirconia connection (12.9 ±0.97 dental units, minimum 12, maximum 14), 72 partial with a zirconia connection (3.11 ±1.12, minimum 2, maximum 7), 15 partial with a titanium base (3.62 ±1.02, minimum 2, maximum 5). Forty ISZFDPs had been in function for ≥10 years (36%), 38 for 5 to 9 years (34.2%), and 33 for 2 to 4 years (22.8%). The mean follow-up time was 7.2 ±3.4 years. No zirconia fractures were identified. Two implants and 2 ISZFDPs failed, with chipping being the most common complication (13.5%). The implant survival rate was 99.4%, and the prosthetic survival rate was 98.2%. The cumulative prosthetic success rate was 91.9%. MBL change was -0.18 ±0.59 mm. Thirteen implants were treated for peri-implantitis (3.8%), and 9 for mucositis (2.7%), but presented healthy peri-implant soft tissues at the follow-up examination. A significant difference was found between the implant-level and abutment-level prostheses (P=.013), with less marginal bone loss observed in ISZFDPs delivered at the implant level. Conclusions: Zirconia-based screw-retained implant-supported prosthesis can be considered a reliable long-term treatment option for partial and complete edentulism. No zirconia fractures were experienced. Stable bone levels and low peri-implantitis rates were reported regardless of the ISZFDP type and level, implant type and connection, and type of loading. © 2021 Editorial Council of the Journal of Prosthetic Dentistry}, keywords = {Aged; Aged; Middle Aged; Middle Aged; Humans; human; Retrospective Studies; clinical trial; retrospective study; multicenter study; Bone Screws; TITANIUM; TITANIUM; Dental Restoration Failure; Dental Implants; Dental Prosthesis, Implant-Supported; bone screw; Peri-implantitis; tooth implant; periimplantitis; dental restoration; implant-supported denture}, year = {2023}, eissn = {1097-6841}, pages = {96-108}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:33859089, title = {Effect of splinting scan bodies on trueness of complete-arch implant impression using different intraoral scanners: an in vitro study}, url = {https://m2.mtmt.hu/api/publication/33859089}, author = {Retana, L. and Nejata, A.H. and Pozzi, Alessandro}, doi = {10.3290/j.ijcd.b2599297}, journal-iso = {INT J COMPUT DENT}, journal = {INTERNATIONAL JOURNAL OF COMPUTERIZED DENTISTRY}, volume = {26}, unique-id = {33859089}, issn = {1463-4201}, abstract = {Aim: To evaluate the trueness of seven different intraoral scanners (IOSs) in making a completearch digital scan with and without splinting the scan bodies. Materials and methods: A polyurethane cast of an edentu lous mandible with four dental implant analogs was pre pared. A reference scan was made using a laboratory scan ner. The reference model was scanned with each of the seven investigated IOSs (control groups, n = 10 per scanner), and scanned again after splinting the scan bodies (study groups, n = 10 per scanner). Each scan was exported as a standard tessellation language (STL) file and transferred to a compre hensive metrology software program (Geomagic Control X). In order to measure the trueness, four points (A, B, C, and D) were determined on the scan bodies, and the distance between point A and the other points (DAB, DAC, and DAD) was measured. The measurements were tested for normality using the KolmogorovSmirnov test and probability plots. Trueness was compared using threeway analysis of variance (ANOVA), and pairwise comparisons were performed using the post hoc Tukey and paired sample t tests. Statistical analyses were twosided, and the significance level was set at 5%. Results: Splinting the scan bodies improved the trueness values of the digital scans, while increasing the interimplant distance decreased them. A significant association was found between the trueness values and all three tested vari ables, including splinting the scan bodies, type of IOS, and interimplant distance (P < 0.001). Conclusion: Based on the present findings, splinting the scan bodies can improve the trueness of completearch digi tal implant scans due to the improvement in morphologic landmarks by the stitching process, regardless of the type of IOS or the interimplant distance. (Int J Comput Dent 2023;26(1): 19–28; doi: 10.3290/j.ijcd.b2599297) © 2023, Quintessenz Verlags-GmbH}, keywords = {Humans; human; Imaging, Three-Dimensional; Computer aided design; Dental Implants; Dental Impression Technique; dental impression; Computer-Aided Design; Dental implant; tooth implant; Trueness; intraoral scanner; splinting; Three-Dimensional Imaging; digital scan; scan body; Models, Dental}, year = {2023}, eissn = {1463-4201}, pages = {19-28}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:33858959, title = {Clinical outcomes of full-arch immediate fixed prostheses supported by two axial and two tilted implants: A retrospective cohort study with 12-15 years of follow-up}, url = {https://m2.mtmt.hu/api/publication/33858959}, author = {Agliardi, Enrico Luigi and Pozzi, Alessandro and Romeo, Davide and Del, Fabbro Massimo}, doi = {10.1111/clr.14047}, journal-iso = {CLIN ORAL IMPLANTS RES}, journal = {CLINICAL ORAL IMPLANTS RESEARCH}, volume = {34}, unique-id = {33858959}, issn = {0905-7161}, abstract = {PurposeTo retrospectively assess clinical and radiographic outcomes of immediately loaded full-arch fixed prostheses supported by axial and tilted implants up to 15 years of function. Materials and MethodsPatients with one completely edentulous arch received an immediate full-arch fixed prosthesis supported by two anterior axial and two posterior tilted implants. Definitive prosthesis consisting of a CAD-CAM titanium framework and acrylic teeth was delivered 6 months later. Patients were regularly followed to assess clinical parameters and marginal bone level (MBL) change. Multilevel regression analysis was performed to investigate factors affecting implant failure and MBL. ResultsSix hundred ninety-two implants were placed in 72 maxillae and 101 mandibles. Seven maxillary implants (5 axial and 2 tilted) in 6 patients and 12 mandibular implants (6 axial and 6 tilted) in 5 patients failed. 15-year cumulative implant survival was 97.51% and 96.91% in maxilla and mandible, respectively (p = .64). After 10 years, the difference in MBL between axial and tilted implants was not significant in the maxilla (p = .47, 65 patients), while it was in the mandible (p < .001, 80 patients). Significant higher bone loss was reported in the mandible at both 5- and 10-year follow-up (p < .001 and p = .004, respectively). Mixed-effect multilevel linear regression evidenced a correlation between arch and bone loss at 5- and 10-year follow-up, while no correlation was found with age, gender, smoking, diabetes, and history of periodontal disease. ConclusionThis long-term study suggests that the present technique can be considered a viable treatment modality for the immediate rehabilitation of both maxilla and mandible.}, keywords = {SURVIVAL; PROPOSAL; SUCCESS; periodontitis; Dental Implants; rehabilitation; Immediate loading; Dentistry, Oral Surgery & Medicine; Marginal bone loss; axial implants; full-arch fixed prosthesis; EDENTULOUS MAXILLAE; MARGINAL BONE}, year = {2023}, eissn = {1600-0501}, pages = {351-366}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186} } @article{MTMT:33858964, title = {Immediately provisionalized tapered conical connection implants for single-tooth restorations in the maxillary esthetic zone: a 5-year prospective single-cohort multicenter analysis}, url = {https://m2.mtmt.hu/api/publication/33858964}, author = {Baer, Russell A. and Noelken, Robert and Colic, Snjezana and Heydecke, Guido and Mirzakhanian, Christine and Behneke, Alexandra and Behneke, Nikolaus and Gottesman, Edward and Ottria, Liliana and Pozzi, Alessandro and Fuegl, Alexander and Zechner, Werner}, doi = {10.1007/s00784-021-04328-2}, journal-iso = {CLIN ORAL INVEST}, journal = {CLINICAL ORAL INVESTIGATIONS}, volume = {26}, unique-id = {33858964}, issn = {1432-6981}, abstract = {Objectives This open, single-cohort, multicenter, prospective study investigated the efficacy of immediately provisionalized tapered conical connection implant for single-tooth restorations in the anterior and premolar regions of the maxilla after 5 years of function. Materials and methods All implants were placed in healed sites and immediately provisionalized. MBLs, soft-tissue parameters, and oral-health impact profile (OHIP) were evaluated at implant insertion, 6, 12, 24, 36, and 60 months. Paired Wilcoxon signed-rank tests and Kaplan-Meier survival analysis was used for statistical and implant survival/success analyses, respectively. Results Seventy-seven patients (81 implants) completed the 5-year follow-up. The 5-year cumulative survival and success rates were 97.8%, and the mean MBL change from implant insertion to 5 years was - 0.80 +/- 1.13 mm. Optimal papilla index scores were observed at 90.1% of sites at 5 years compared with 32.8% of sites at insertion. Pink esthetic score, modified bleeding and plaque indices, and OHIP showed statistically significant improvement at the 5-year follow-up. Conclusions Immediately provisionalized tapered conical connection implants promote marginal bone stability and excellent esthetic outcomes after 5 years of function.}, keywords = {SITES; EXTRACTION; FOLLOW-UP; PLACEMENT; bone remodeling; Crowns; SOFT-TISSUE; ANTERIOR MAXILLA; ANTERIOR MAXILLA; immediate provisionalization; Conical connection; Soft tissue response; VARIABLE-THREAD}, year = {2022}, eissn = {1436-3771}, pages = {3593-3604}, orcid-numbers = {Pozzi, Alessandro/0000-0002-3052-8186; Zechner, Werner/0000-0002-4142-9992} } @article{MTMT:33858963, title = {Accuracy of Computer-Assisted Flapless Implant Placement by Means of Mucosa-Supported Templates in Complete-Arch Restorations: A Systematic Review}, url = {https://m2.mtmt.hu/api/publication/33858963}, author = {Carosi, Paolo and Lorenzi, Claudia and Lio, Fabrizio and Cardelli, Pierluigi and Pinto, Alessandro and Laureti, Andrea and Pozzi, Alessandro}, doi = {10.3390/ma15041462}, journal-iso = {MATERIALS}, journal = {MATERIALS}, volume = {15}, unique-id = {33858963}, abstract = {The aim of this study was to systematically review the current scientific literature regarding the accuracy of fully guided flapless implant positioning for complete-arch rehabilitations in edentulous patients and to assess if there was any statistically significant correlation between linear deviation at shoulder point, at apex point and angular deviation. The electronic and manual literature search of clinical studies was carried out using specified indexing terms. A total of 13 studies were eligible for qualitative analysis and 277 edentulous patients were rehabilitated with 1556 implants patients by means of fully guided mucosa-supported template-assisted flapless surgery. Angular deviation was 3.42 degrees (95% CI 2.82-4.03), linear deviation at shoulder point 1.23 mm (95% CI 0.97-1.49) and linear deviation at apex point 1.46 mm (95% CI 1.17-1.74). No statistically significant correlations were found between the linear and angular deviations. A statistically significant correlation was found between the two linear deviations (correlation coefficient 0.91) that can be summarized by the regression equation y = 0.03080 + 0.8254x. Computer-assisted flapless implant placement by means of mucosa-supported templates in complete arch restorations can be considered a reliable and predictable treatment choice despite the potential effects that flapless approach could bring to the overall treatment.}, keywords = {Bone; Chemistry, Physical; Dental Implants; prosthesis; rehabilitation; RETROSPECTIVE ANALYSIS; RANDOMIZED CLINICAL-TRIAL; Immediate loading; GUIDED SURGERY; Materials Science, Multidisciplinary; Physics, Applied; Metallurgy & Metallurgical Engineering; edentulous maxilla; Digital workflow; computer-guided-surgery; STEREOLITHOGRAPHIC SURGICAL TEMPLATES}, year = {2022}, eissn = {1996-1944}, orcid-numbers = {Carosi, Paolo/0000-0002-2442-1091; Lorenzi, Claudia/0000-0003-3555-8146; Lio, Fabrizio/0000-0001-7071-3127; Pozzi, Alessandro/0000-0002-3052-8186} }