TY  - JOUR
AU  - Alijanpourotaghsara, Amirreza
AU  - Vessal, Arsalan
AU  - Alijanpour, Amirmasoud
AU  - Strelnikov, David
AU  - Piroska, Márton
AU  - Persely, Aliz
AU  - Jokkel, Zsófia
AU  - Szalontai, László
AU  - Forgo, Bianka
AU  - Kozák, Lajos Rudolf
AU  - Bekesy-Szabo, Adam
AU  - Maurovich-Horvat, Pál
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - Morphometric Analysis of Neocortical and Infratentorial Structures: Genetic and Environmental Insights from a Twin Neuroanatomical Study
JF  - MEDICINA-LITHUANIA
J2  - MED LITH
VL  - 61
PY  - 2025
IS  - 2
PG  - 18
SN  - 1010-660X
DO  - 10.3390/medicina61020261
UR  - https://m2.mtmt.hu/api/publication/35773338
ID  - 35773338
AB  - Background and Objective: Brain morphometry is shaped by a complex interplay of genetic and environmental factors, including physiological and neuropsychiatric conditions. These influences can vary across distinct brain regions, yet the precise contributions of genetics and environment to regional variation in healthy brains remain poorly understood. This study examines the heritability of specific brain structures to provide deeper insights into their development. Materials and Methods: We studied 118 healthy adult twins from the Hungarian Twin Registry using T1-weighted magnetic resonance imaging (T1W MRI) and the volBrain pipeline for structural measurements. Results: In all regions, monozygotic (MZ) twins showed a higher resemblance than dizygotic (DZ) twins in total brainstem and cerebellar volumes, with significant heritability (A: 90.5–92.6%) and minimal unique environmental effects (E: <1%). For supratentorial regions, regarding the total gray matter volume, all regions exhibited high heritability (A: 74.5–92.4%) and minimal environmental influence (E: <1.5%). In average cortical thickness analysis, the frontal lobe, temporal lobe, and pre-central gyrus were influenced by shared and unique environmental factors (C: 63–66.5%; E: 33.4–37%), whereas genetics were more prominent in the parietal lobe, occipital lobe, and post-central gyrus (A: 67.7–85%; E: 15–32.3%). Conclusions: Genetics strongly influence cortical gray matter volume in supratentorial regions (both total and regional), as well as the total brainstem volume and the total and cortical gray matter volumes of the cerebellum in infratentorial regions. This genetic influence extends to the average cortical thickness of the parietal lobe, post-central gyrus, and occipital lobe, while the frontal lobe, temporal lobe, and pre-central gyrus are more affected by environmental factors. These findings emphasize the importance of understanding region-specific genetic and environmental contributions to brain structure, which could guide personalized therapeutic and preventive strategies for neurological conditions.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Vessal, Arsalan
AU  - Alijanpourotaghsara, Amirreza
AU  - Strelnikov, David
AU  - Persely, Aliz
AU  - Piroska, Márton
AU  - Alijanpour, A.
AU  - Jokkel, Zsófia
AU  - Szalontai, László
AU  - Forgo, B.
AU  - Kozák, Lajos Rudolf
AU  - Bekesy-Szabo, A.
AU  - Maurovich-Horvat, Pál
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - The interplay of genetic and environmental factors on the morphology of the limbic cortex and hippocampal subfields: Insights from an MRI twin study
JF  - PSYCHIATRY RESEARCH-NEUROIMAGING
J2  - PSYCHIAT RES-NEUROIM
VL  - 345
PY  - 2024
PG  - 8
SN  - 0925-4927
DO  - 10.1016/j.pscychresns.2024.111909
UR  - https://m2.mtmt.hu/api/publication/35472997
ID  - 35472997
N1  - Medical Imaging Centre, Semmelweis University, Budapest1082, Hungary            
            Department of Radiology, Faculty of Medicine and Health, Örebro University, Örebro, 702 81, Sweden            
            Export Date: 28 January 2025            
            CODEN: PSREE            
            Correspondence Address: Tarnoki, A.D.; Medical Imaging Centre, Budapest, Hungary; email: tarnoki2@gmail.com
LA  - English
DB  - MTMT
ER  - 

TY  - GEN
AU  - Arsalan, Vessal
AU  - Strelnikov, David
AU  - Alijanpourotaghsara, Amirreza
AU  - Piroska, Márton
AU  - Szalontai, László
AU  - Forgó, Bianka
AU  - Jokkel, Zsófia
AU  - Persely, Aliz
AU  - Hernyes, Anita
AU  - Kozák, Lajos Rudolf
AU  - Szabó, Ádám György
AU  - Maurovich-Horvat, Pál
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - Genetic and environmental influences on limbic system grey matter structures: insights from an MRI twin study
PY  - 2023
UR  - https://m2.mtmt.hu/api/publication/34055774
ID  - 34055774
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Vessal, A
AU  - Alijanpourotaghsara, A
AU  - Strelnikov, David
AU  - Piroska, M
AU  - Szalontai, L
AU  - Forgo, B
AU  - Jokkel, Z
AU  - Persely, A
AU  - Hernyes, A
AU  - Kozak, LR
AU  - Szabo, A
AU  - Maurovich-Horvat, P
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - Exploring the Interplay of Genetic and Environmental Factors on the Morphology of the Limbic Cortex and Hippocampal Subfields: Insights from an MRI Twin Study
JF  - ARCHIVES OF THE HUNGARIAN MEDICAL ASSOCIATION OF AMERICA
J2  - ARCH HUNG MED ASSOC AM
VL  - 29
PY  - 2023
IS  - 1
SP  - 9
EP  - 10
PG  - 2
SN  - 1070-0773
UR  - https://m2.mtmt.hu/api/publication/34160959
ID  - 34160959
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Strelnikov, David
AU  - Alijanpourotaghsara, A
AU  - Vessal, A
AU  - Piroska, M
AU  - Szalontai, L
AU  - Forgo, B
AU  - Jokkel, Z
AU  - Persely, A
AU  - Hernyes, A
AU  - Kozak, LR
AU  - Szabo, A
AU  - Maurovich-Horvat, P
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - A Twin Study Examining the Volume of Subcortical Grey Matter Structures
JF  - ARCHIVES OF THE HUNGARIAN MEDICAL ASSOCIATION OF AMERICA
J2  - ARCH HUNG MED ASSOC AM
VL  - 29
PY  - 2023
IS  - 1
SP  - 30
EP  - 31
PG  - 1
SN  - 1070-0773
UR  - https://m2.mtmt.hu/api/publication/34160961
ID  - 34160961
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Szabó, I
AU  - Ghimessy, Áron
AU  - Andi, J
AU  - Török, Klára
AU  - Fillinger, János
AU  - Szőke, János
AU  - Báthory-Fülöp, László
AU  - Radeczky, Péter
AU  - Agócs, László
AU  - Turóczi-Kirizs, R
AU  - Kerpel-Fronius, Anna
AU  - Szalontai, L
AU  - Benczúr, A
AU  - Kerepesi, Csaba
AU  - Németh, B
AU  - Tóth, Bertalan
AU  - Alijanpourotaghsara, A
AU  - Strelnikov, David
AU  - Vessal, A
AU  - Gődény, Mária
AU  - Rényi-Vámos, Ferenc István
AU  - Tárnoki, Ádám Domonkos
AU  - Tárnoki, Dávid László
TI  - Tüdőtumorok radiogenomikai vizsgálata
JF  - MAGYAR RADIOLÓGIA ONLINE
J2  - MAGYAR RADIOLÓGIA ONLINE
VL  - 14
PY  - 2023
IS  - 2
SP  - 35
SN  - 2063-9481
UR  - https://m2.mtmt.hu/api/publication/34161824
ID  - 34161824
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Martinovszky, Fruzsina
AU  - Beszedics, Beatrix
AU  - Németh, Bálint
AU  - Salfiti, Juszef
AU  - Alijanpourotaghsara, Amirreza
AU  - Strelnikov, David
AU  - Török, Bálint
AU  - Ujlaki, Mátyás
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - Emlőtumor vizsgálata ikrekben
JF  - MAGYAR RADIOLÓGIA ONLINE
J2  - MAGYAR RADIOLÓGIA ONLINE
VL  - 14
PY  - 2023
IS  - 2
SP  - 36
SN  - 2063-9481
UR  - https://m2.mtmt.hu/api/publication/34161825
ID  - 34161825
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Szabo, I
AU  - Ghimessy, Áron
AU  - Andi, J
AU  - Török, Klára
AU  - Fillinger, János
AU  - Szőke, János
AU  - Báthory-Fülöp, László
AU  - Radeczky, Péter
AU  - Agócs, László
AU  - Turóczi-Kirizs, R
AU  - Kerpel-Fronius, Anna
AU  - Szalontai, L
AU  - Benczúr, A
AU  - Kerepesi, C
AU  - Németh, B
AU  - Tóth, B
AU  - Alijanpourotaghsara, A
AU  - Strelnikov, David
AU  - Vessal, A
AU  - Gődény, Mária
AU  - Rényi-Vámos, Ferenc István
AU  - Tárnoki, Ádám Domonkos
AU  - Tárnoki, Dávid László
TI  - Radiogenomic analysis of NSCLC
JF  - ARCHIVES OF THE HUNGARIAN MEDICAL ASSOCIATION OF AMERICA
J2  - ARCH HUNG MED ASSOC AM
VL  - 29
PY  - 2023
IS  - 1
SP  - 7
EP  - 7
PG  - 1
SN  - 1070-0773
UR  - https://m2.mtmt.hu/api/publication/34161831
ID  - 34161831
LA  - English
DB  - MTMT
ER  - 

TY  - CONF
AU  - Alijanpourotaghsara, A
AU  - Strelnikov, David
AU  - Vessal, A
AU  - Piroska, M
AU  - Szalontai, L
AU  - Forgo, B
AU  - Jokkel, Z
AU  - Persely, A
AU  - Hernyes, A
AU  - Kozak, LR
AU  - Szabo, A
AU  - Maurovich-Horvat, P
AU  - Tárnoki, Dávid László
AU  - Tárnoki, Ádám Domonkos
TI  - Genetic and environmental influences on limbic system grey matter structures: Insights from an MRI twin study
T2  - Abstract book of the Twins Congress 2023
C1  - Budapest
PY  - 2023
SP  - 76
UR  - https://m2.mtmt.hu/api/publication/34175695
ID  - 34175695
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Persely, Aliz
AU  - Beszedics, B.
AU  - Pálóczi, Krisztina
AU  - Piroska, Márton
AU  - Alijanpourotaghsara, Amirreza
AU  - Strelnikov, David
AU  - Vessal, A.
AU  - Szabó, Helga
AU  - Hernyes, Anita
AU  - Zöldi, Luca
AU  - Jokkel, Zsófia
AU  - Fekete, A.
AU  - Juhász, János
AU  - Makra, Nóra
AU  - Szabó, Dóra
AU  - Buzás, Edit Irén
AU  - Tárnoki, Ádám Domonkos
AU  - Tárnoki, Dávid László
TI  - Analysis of Genetic and MRI Changes, Blood Markers, and Risk Factors in a Twin Pair Discordant of Progressive Supranuclear Palsy
JF  - MEDICINA-LITHUANIA
J2  - MED LITH
VL  - 59
PY  - 2023
IS  - 10
PG  - 18
SN  - 1010-660X
DO  - 10.3390/medicina59101696
UR  - https://m2.mtmt.hu/api/publication/34271363
ID  - 34271363
N1  - Medical Imaging Centre, Semmelweis University, Budapest, 1082, Hungary            
            Neurology Department, Medical Centre Hungarian Defence Forces, Budapest, 1134, Hungary            
            Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, 1085, Hungary            
            Central Radiological Diagnostic Department, Medical Centre Hungarian Defence Forces, Budapest, 1134, Hungary            
            Institute of Medical Microbiology, Semmelweis University, Budapest, 1085, Hungary            
            Faculty of Information Technology and Bionics, Pazmany Peter Catholic University, Budapest, 1085, Hungary            
            Export Date: 23 January 2024            
            Correspondence Address: Tarnoki, D.L.; Medical Imaging Centre, Hungary; email: tarnoki4@gmail.com            
            Chemicals/CAS: Biomarkers
LA  - English
DB  - MTMT
ER  -