TY - JOUR AU - Veres, Szilárd AU - Martinovszky, Fruzsina AU - Di Giovanni, Márk AU - Budai, Bettina Katalin AU - Beszedics, Beatrix AU - Szabó, István AU - Butz, Henriett AU - Patócs, Attila Balázs AU - Török, Bálint AU - Ujlaki, Mátyás AU - Tárnoki, Dávid László AU - Tárnoki, Ádám Domonkos TI - Emlődenzitás vizsgálata emlőrákdiszkordáns ikerpárok esetében JF - MAGYAR ONKOLÓGIA J2 - MAGYAR ONKOLÓGIA VL - 68 PY - 2024 IS - 2 SP - 171 EP - 176 PG - 6 SN - 0025-0244 UR - https://m2.mtmt.hu/api/publication/35145110 ID - 35145110 N1 - Országos Onkológiai Intézet, Onkológiai Képalkotó és Invazív Diagnosztikai Központ, Budapest, Hungary Nemzeti Tumorbiológiai Laboratórium, Budapest, Hungary Molekuláris Genetikai Osztály, Budapest, Hungary Semmelweis Egyetem, Orvosi Képalkotó Klinika, Budapest, Hungary Export Date: 24 September 2024 CODEN: MGONA Correspondence Address: Domonkos, T.Á.; Országos Onkológiai Intézet, Ráth György u. 7–9, Hungary; email: tarnoki.adam@oncol.hu Chemicals/CAS: BRCA2 Protein AB - Previous twin studies show that genetic factors are responsible for 63% of the variability in breast density. We analyzed the mammographic images of 9 discordant twin pairs for breast cancer from the population-based Hungarian Twin Registry. We measured breast density using 3D Slicer software. Genetic variants predisposing to breast cancer were also examined. One of the examined twin pairs had a BRCA2 mutation in both members. There was no significant difference between the mean values of breast density in the tumor and non-tumor groups (p=0.323). In terms of parity and the presence of menopause, we found mostly no significant difference between the members of the twin pair. In our cohort of identical twins discordant for breast cancer, the average breast density showed no significant difference, which can be explained by the common genetic basis of breast cancer and breast density. LA - Hungarian DB - MTMT ER - TY - JOUR AU - Martinovszky, Fruzsina AU - Beszedics, Beatrix AU - Németh, Bálint AU - Salfiti, Juszef AU - Alijanpourotaghsara, Amirreza AU - Strelnikov, David AU - Török, Bálint AU - Ujlaki, Mátyás AU - Tárnoki, Dávid László AU - Tárnoki, Ádám Domonkos TI - Emlőtumor vizsgálata ikrekben JF - MAGYAR RADIOLÓGIA ONLINE J2 - MAGYAR RADIOLÓGIA ONLINE VL - 14 PY - 2023 IS - 2 SP - 36 SN - 2063-9481 UR - https://m2.mtmt.hu/api/publication/34161825 ID - 34161825 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Csala, Irén AU - Eleméry, Mónika AU - Martinovszky, Fruzsina AU - Döme, Péter AU - Döme, Balázs AU - Faludi, Gábor AU - Sándor, Imola AU - Győrffy, Zsuzsa AU - Birkás, Emma AU - Lazáry, Judit TI - Maternal bonding styles in smokers and non-smokers: a comparative study JF - ANNALS OF GENERAL PSYCHIATRY J2 - ANN GEN PSYCHIATRY VL - 15 PY - 2016 PG - 7 SN - 1744-859X DO - 10.1186/s12991-016-0118-y UR - https://m2.mtmt.hu/api/publication/3140530 ID - 3140530 N1 - Funding Agency and Grant Number: Norwegian Financial Mechanism [HU0125]; Hungarian Academy of Sciences Janos Bolyai Research Grant Funding text: This study was funded by the Norwegian Financial Mechanism (HU0125). Zsuzsa Gyorffy and Peter Dome were supported by the Hungarian Academy of Sciences Janos Bolyai Research Grant. AB - BACKGROUND: Parental bonding has been implicated in smoking behavior, and the quality of maternal bonding (MB) has been associated with poor mental health and substance use. However, little is known about the association of MB and the smoking of the offspring. METHODS: In our study, 129 smokers and 610 non-smoker medical students completed the parental bonding instrument, which measures MB along two dimensions: care and overprotection. Four categories can be created by high and low scores on care and overprotection: optimal parenting (OP; high care/low overprotection); affectionless control (ALC; low care/high overprotection); affectionate constraint (AC; high care/high overprotection), and neglectful parenting (NP; low care/low overprotection). Nicotine dependence was assessed by the Fagerstrom Nicotine Dependence Test, exhaled CO level, and daily cigarette consumption (CPD). RESULTS: Higher CPD was significantly associated with lower overprotection (p = 0.016) and higher care (p = 0.023) scores. The odds for being a smoker were significantly higher in the neglectful maternal bonding style compared to the other rearing styles (p = 0.022). Besides, smokers showed significantly higher care and lower overprotection scores with the Mann-Whitney U-test than non-smokers, although these associations did not remain significant in multiple regression models. CONCLUSION: Our results indicate that focusing on early life relationship between patient and mother can be important in psychotherapeutic interventions for smoking. Registration trials retrospectively registered. LA - English DB - MTMT ER - TY - JOUR AU - Tárnoki, Dávid László AU - Tárnoki, Ádám Domonkos AU - Kovács, Dániel Tamás AU - Forgó, Bianka AU - Martinovszky, Fruzsina AU - Gáll, Orsolya AU - Littvay, Levente AU - Losonczy, György AU - Kunos, László AU - Bikov, András TI - Az alvás alatti légzészavarok hátterében álló örökletes tényezők: egy ikervizsgálat tapasztalatai JF - MEDICINA THORACALIS (BUDAPEST) J2 - MED THORAC (BP) VL - 69 PY - 2016 IS - 2 SP - 87 EP - 95 PG - 9 SN - 0238-2571 UR - https://m2.mtmt.hu/api/publication/3081280 ID - 3081280 LA - Hungarian DB - MTMT ER - TY - JOUR AU - Martinovszky, Fruzsina AU - Zsolyomi, M AU - Tárnoki, Ádám Domonkos AU - Tárnoki, Dávid László AU - Losonczy, György AU - Kunos, László AU - Bikov, András TI - Overnight changes in lung function in patients with obstructive sleep apnoea JF - EUROPEAN RESPIRATORY JOURNAL J2 - EUR RESPIR J VL - 46 PY - 2015 IS - Suppl 59 SN - 0903-1936 DO - 10.1183/13993003.congress-2015.PA2367 UR - https://m2.mtmt.hu/api/publication/2989784 ID - 2989784 LA - English DB - MTMT ER - TY - JOUR AU - Lázár, Zsófia AU - Bikov, András AU - Martinovszky, Fruzsina AU - Gálffy, Gabriella AU - Losonczy, György AU - Horváth, Ildikó TI - A kilégzett levegő hőmérsékletének mérése stabil és exacerbált COPD-s betegekben JF - MEDICINA THORACALIS (BUDAPEST) J2 - MED THORAC (BP) VL - 68 PY - 2015 IS - 4 SP - 257 EP - 262 PG - 6 SN - 0238-2571 UR - https://m2.mtmt.hu/api/publication/2933721 ID - 2933721 LA - Hungarian DB - MTMT ER -