@mastersthesis{MTMT:32860647,
	title = {Challenges in the treatment and follow up of acute pancreatitis [Kihívások az akut pancreatitis kezelésében és utánkövetésében]},
	url = {https://m2.mtmt.hu/api/publication/32860647},
	author = {Szabó-Halász, Adrienn},
	doi = {10.14232/phd.11073},
	publisher = {SZTE},
	unique-id = {32860647},
	year = {2022}
}

@article{MTMT:32823615,
	title = {Early prediction of acute necrotizing pancreatitis by artificial intelligence : a prospective cohort-analysis of 2387 cases},
	url = {https://m2.mtmt.hu/api/publication/32823615},
	author = {Kiss, Szabolcs and Pintér, József and Molontay, Roland and Nagy, Marcell and Borbásné Farkas, Kornélia and Sipos, Zoltán and Fehérvári, Péter and Pecze, László and Földi, Mária and Vincze, Áron and Takács, Tamás and Czakó, László and Szabó-Halász, Adrienn and Boros, Eszter and Hamvas, József and Varga, Márta and Mickevicius, Artautas and Faluhelyi, Nándor and Farkas, Orsolya and Váncsa, Szilárd and Nagy, Rita and Bunduc, Stefania and Hegyi, Péter Jenő and Márta, Katalin and Borka, Katalin and Doros, Attila and Hosszúfalusi, Nóra and Zubek, László and Erőss, Bálint Mihály and Molnár, Zsolt and Párniczky, Andrea and Hegyi, Péter and Szentesi, Andrea Ildikó and Izbéki, Ferenc},
	doi = {10.1038/s41598-022-11517-w},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {12},
	unique-id = {32823615},
	issn = {2045-2322},
	abstract = {Pancreatic necrosis is a consistent prognostic factor in acute pancreatitis (AP). However, the clinical scores currently in use are either too complicated or require data that are unavailable on admission or lack sufficient predictive value. We therefore aimed to develop a tool to aid in necrosis prediction. The XGBoost machine learning algorithm processed data from 2387 patients with AP. The confidence of the model was estimated by a bootstrapping method and interpreted via the 10th and the 90th percentiles of the prediction scores. Shapley Additive exPlanations (SHAP) values were calculated to quantify the contribution of each variable provided. Finally, the model was implemented as an online application using the Streamlit Python-based framework. The XGBoost classifier provided an AUC value of 0.757. Glucose, C-reactive protein, alkaline phosphatase, gender and total white blood cell count have the most impact on prediction based on the SHAP values. The relationship between the size of the training dataset and model performance shows that prediction performance can be improved. This study combines necrosis prediction and artificial intelligence. The predictive potential of this model is comparable to the current clinical scoring systems and has several advantages over them.},
	year = {2022},
	eissn = {2045-2322},
	orcid-numbers = {Molontay, Roland/0000-0002-0666-5279; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Sipos, Zoltán/0000-0001-7845-8116; Vincze, Áron/0000-0003-2217-7686; Czakó, László/0000-0002-6331-0802; Váncsa, Szilárd/0000-0002-9347-8163; Nagy, Rita/0000-0002-2663-4912; Márta, Katalin/0000-0002-2213-4865; Borka, Katalin/0000-0002-8956-0770; Doros, Attila/0000-0002-6496-9895; Hosszúfalusi, Nóra/0000-0002-9469-372X; Zubek, László/0000-0003-0583-3290; Erőss, Bálint Mihály/0000-0003-3658-8427; Hegyi, Péter/0000-0003-0399-7259; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Németh, Balázs/0000-0001-5338-7577; Papp, Mária/0000-0003-3662-4010; Szakács, Zsolt/0000-0002-7035-941X; Izbéki, Ferenc/0000-0001-7767-4319}
}

@article{MTMT:31815619,
	title = {Evidence for diagnosis of early chronic pancreatitis after three episodes of acute pancreatitis: a cross-sectional multicentre international study with experimental animal model},
	url = {https://m2.mtmt.hu/api/publication/31815619},
	author = {Hegyi, Péter Jenő and Soós, Alexandra and Tóth, Emese and Ébert, Attila and Venglovecz, Viktória and Márta, Katalin and Mátrai, Péter and Mikó, Alexandra and Bajor, Judit and Sarlós, Patrícia and Vincze, Áron and Szabó-Halász, Adrienn and Izbéki, Ferenc and Szepes, Zoltán and Czakó, László and Kovács, György and Papp, Mária and Dubravcsik, Zsolt and Varga, Márta and Hamvas, József and Németh, Balázs and Macarie, Melania and Ince, Ali Tüzün and Bordin, Dmitry S and Dubtsova, Elena A and Kiryukova, Mariya A and Khatkov, Igor E and Bideeva, Tanya and Mickevicius, Artautas and Ramírez-Maldonado, Elena and Sallinen, Ville and Erőss, Bálint Mihály and Pécsi, Dániel and Szentesi, Andrea Ildikó and Párniczky, Andrea and Tiszlavicz, László and Hegyi, Péter},
	doi = {10.1038/s41598-020-80532-6},
	journal-iso = {SCI REP},
	journal = {SCIENTIFIC REPORTS},
	volume = {11},
	unique-id = {31815619},
	issn = {2045-2322},
	abstract = {Chronic pancreatitis (CP) is an end-stage disease with no specific therapy; therefore, an early diagnosis is of crucial importance. In this study, data from 1315 and 318 patients were analysed from acute pancreatitis (AP) and CP registries, respectively. The population from the AP registry was divided into AP (n = 983), recurrent AP (RAP, n = 270) and CP (n = 62) groups. The prevalence of CP in combination with AP, RAP2, RAP3, RAP4 and RAP5 + was 0%, 1%, 16%, 50% and 47%, respectively, suggesting that three or more episodes of AP is a strong risk factor for CP. Laboratory, imaging and clinical biomarkers highlighted that patients with RAP3 + do not show a significant difference between RAPs and CP. Data from CP registries showed 98% of patients had at least one AP and the average number of episodes was four. We mimicked the human RAPs in a mouse model and found that three or more episodes of AP cause early chronic-like morphological changes in the pancreas. We concluded that three or more attacks of AP with no morphological changes to the pancreas could be considered as early CP (ECP).The new diagnostic criteria for ECP allow the majority of CP patients to be diagnosed earlier. They can be used in hospitals with no additional costs in healthcare.},
	year = {2021},
	eissn = {2045-2322},
	orcid-numbers = {Venglovecz, Viktória/0000-0002-2316-7247; Márta, Katalin/0000-0002-2213-4865; Sarlós, Patrícia/0000-0002-5086-9455; Vincze, Áron/0000-0003-2217-7686; Izbéki, Ferenc/0000-0001-7767-4319; Szepes, Zoltán/0000-0002-9466-8719; Czakó, László/0000-0002-6331-0802; Papp, Mária/0000-0003-3662-4010; Dubravcsik, Zsolt/0000-0002-7231-3300; Németh, Balázs/0000-0001-5338-7577; Erőss, Bálint Mihály/0000-0003-3658-8427; Pécsi, Dániel/0000-0003-0499-6004; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Tiszlavicz, László/0000-0003-1134-6587; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31822032,
	title = {The new definition of early chronic pancreatitis},
	url = {https://m2.mtmt.hu/api/publication/31822032},
	author = {Hegyi, P and Soós, A and Tóth, Emese and Ébert, Attila and Venglovecz, Viktória and Márta, K and Mátrai, P and Mikó, A and Bajor, Judit and Sarlós, P and Szabó-Halász, Adrienn and Izbéki, F and Szepes, Zoltán and Czakó, László and Kovács, G and Papp, M and Dubravcsik, Zsolt and Varga, M and Hamvas, J and Németh, Balázs and Macarie, Mq and Tüzün, A and Bordin, D and Kiryukova, M and Khatkov, I and Bideeva, T and Mickevicius, A and Ramírez-Maldonado, E and Sallinen, V and ErÖss, B and Pécsi, Dániel and Szentesi, Andrea Ildikó and Párniczky, A and Hegyi, Péter},
	doi = {10.1016/j.pan.2020.07.071},
	journal-iso = {PANCREATOLOGY},
	journal = {PANCREATOLOGY},
	volume = {20},
	unique-id = {31822032},
	issn = {1424-3903},
	year = {2020},
	eissn = {1424-3911},
	pages = {S56-S58},
	orcid-numbers = {Venglovecz, Viktória/0000-0002-2316-7247; Szepes, Zoltán/0000-0002-9466-8719; Czakó, László/0000-0002-6331-0802; Dubravcsik, Zsolt/0000-0002-7231-3300; Németh, Balázs/0000-0001-5338-7577; Pécsi, Dániel/0000-0003-0499-6004; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31819813,
	title = {The use of early achievable severity (EASY) index is beneficial for rapid risk stratification in acute pancreatitis at hospital admission},
	url = {https://m2.mtmt.hu/api/publication/31819813},
	author = {Kui, Balázs and Gódi, S and Bajor, J and Török, I and Macaria, M and Farkas, H and Mickevicius, A and Sallinen, V and Maldonado, E and Papp, M and Kovács, G and Fehér, E and Sarlós, P and Galeev, S and Németh, Balázs and Vincze, Á and Pencik, P and Ozola-Zalite, I and Pukitis, A and Litvin, A and Kovalskaya, I and Czimmer, J and Pár, G and Hritz, István and Illés, Dóra and Szentesi, Andrea Ildikó and Lakatos, L and Capurso, G and Patai, Á and Stilidi, E and Peserico, G and Zadorozhna, K and Sonmez, E and Tüzün, Ince A and Vishalkumar, S and Horibe, M and Ihász, M and Erőss, B and Márta, K and Szakács, Zsolt and Farkas, N and Gede, N and Szabó-Halász, Adrienn and Gajdán, L and Izbéki, F and Poropat, G and Robu, G and Jinga, M and Hegyi, Péter},
	journal-iso = {CENT EUR J GASTRO HEPATOL},
	journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE},
	volume = {6},
	unique-id = {31819813},
	year = {2020},
	eissn = {2415-9107},
	pages = {62-63},
	orcid-numbers = {Németh, Balázs/0000-0001-5338-7577; Hritz, István/0000-0002-8763-6006; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31819695,
	title = {Risk prediction model for developing pancreatic necrosis},
	url = {https://m2.mtmt.hu/api/publication/31819695},
	author = {Kiss, Szabolcs and Farkas, N and Fehérvári, P and Pecze, L and Földi, Mária and Vincze, Á and Gódi, S and Bajor, J and Czimmer, J and Sarlós, P and Hágendorn, R and Takács, Tamás and Izbéki, F and Szabó-Halász, Adrienn and Hamvas, J and Varga, M and Crai, S and Mickevicius, A and Patai, Á and Ihász, M and Varjú, P and Faluhelyi, N and Farkas, O and Miseta, A and Kelemen, Dezső and Papp, R and Hegyi, P and Szentesi, Andrea Ildikó and Párniczky, A and Hegyi, Péter},
	journal-iso = {CENT EUR J GASTRO HEPATOL},
	journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE},
	volume = {6},
	unique-id = {31819695},
	year = {2020},
	eissn = {2415-9107},
	pages = {61},
	orcid-numbers = {Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31784556,
	title = {The new definition of early chronic pancreatitis},
	url = {https://m2.mtmt.hu/api/publication/31784556},
	author = {Hegyi, P and Soós, A and Tóth, Emese and Ébert, Attila and Venglovecz, Viktória and Márta, K and Mikó, A and Bajor, J and Sarlós, P and Vincze, Á and Szabó-Halász, Adrienn and Izbéki, F and Szepes, Zoltán and Czakó, László and Kovács, L. Gábor and Papp, Mária and Dubravcsik, Zsolt and Varga, M and Hamvas, J and Németh, Balázs and Erőss, B and Pécsi, D and Szentesi, Andrea Ildikó and Párniczky, A and Hegyi, Péter},
	journal-iso = {CENT EUR J GASTRO HEPATOL},
	journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE},
	volume = {6},
	unique-id = {31784556},
	year = {2020},
	eissn = {2415-9107},
	pages = {54-54},
	orcid-numbers = {Venglovecz, Viktória/0000-0002-2316-7247; Szepes, Zoltán/0000-0002-9466-8719; Czakó, László/0000-0002-6331-0802; Kovács, L. Gábor/0000-0001-5298-5401; Papp, Mária/0000-0003-3662-4010; Dubravcsik, Zsolt/0000-0002-7231-3300; Németh, Balázs/0000-0001-5338-7577; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31280739,
	title = {Hypertriglyceridemia-induced acute pancreatitis: A prospective, multicenter, international cohort analysis of 716 acute pancreatitis cases},
	url = {https://m2.mtmt.hu/api/publication/31280739},
	author = {Mosztbacher, Dóra and Hanák, Lilla and Borbásné Farkas, Kornélia and Szentesi, Andrea Ildikó and Mikó, Alexandra and Bajor, Judit and Sarlós, Patrícia and Czimmer, József and Vincze, Áron and Hegyi, Péter Jenő and Erőss, Bálint Mihály and Takács, Tamás and Czakó, László and Németh, Balázs and Izbéki, Ferenc and Szabó-Halász, Adrienn and Gajdán, László and Hamvas, József and Papp, Mária and Földi, Ildikó and Fehér, Krisztina Eszter and Varga, Márta and Csefkó, Klára and Török, Imola and Farkas, Hunor Pál and Mickevicius, Artautas and Maldonado, Elena Ramirez and Sallinen, Ville and Novák, János and Ince, Ali Tüzün and Galeev, Shamil and Bod, Barnabás and Sümegi, János and Pencik, Petr and Dubravcsik, Zsolt and Illés, Dóra and Gódi, Szilárd and Kui, Balázs and Márta, Katalin and Pécsi, Dániel and Varjú, Péter and Szakács, Zsolt and Darvasi, Erika and Párniczky, Andrea and Hegyi, Péter},
	doi = {10.1016/j.pan.2020.03.018},
	journal-iso = {PANCREATOLOGY},
	journal = {PANCREATOLOGY},
	volume = {20},
	unique-id = {31280739},
	issn = {1424-3903},
	abstract = {Background Hypertriglyceridemia is the third most common cause of acute pancreatitis (AP). It has been shown that hypertriglyceridemia aggravates the severity and related complications of AP; however, detailed analyses of large cohorts are inadequate and contradictory. Our aim was to investigate the dose-dependent effect of hypertriglyceridemia on AP. Methods AP patients over 18 years old who underwent triglyceride measurement within the initial three days were included into our cohort analysis from a prospective international, multicenter AP registry operated by the Hungarian Pancreatic Study Group. Data on 716 AP cases were analyzed. Six groups were created based on the highest triglyceride level (<1.7 mmol/l, 1.7–2.19 mmol/l, 2.2–5.59 mmol/l, 5.6–11.29 mmol/l, 11.3–22.59 mmol/l, ≥22.6 mmol/l). Results Hypertriglyceridemia (≥1.7 mmol/l) presented in 30.6% of the patients and was significantly and dose-dependently associated with younger age and male gender. In 7.7% of AP cases, hypertriglyceridemia (≥11.3 mmol/l) was considered as a causative etiological factor; however, 43.6% of these cases were associated with other etiologies (alcohol and biliary). Hypertriglyceridemia was significantly and dose-dependently related to obesity and diabetes. The rates of local complications, organ failure and maximum CRP level were significantly and dose-dependently raised by hypertriglyceridemia. Triglyceride above 11.3 mmol/l was linked to a significantly higher incidence of moderately severe AP and longer hospital stay, whereas triglyceride over 22.6 mmol/l was significantly associated with severe AP as well. Conclusion Hypertriglyceridemia dose-dependently aggravates the severity and related complications of AP. Diagnostic workup for hypertriglyceridemia requires better awareness regardless of the etiology of AP.},
	keywords = {ETIOLOGY; HYPERTRIGLYCERIDEMIA; COHORT; SEVERITY; Acute pancreatitis},
	year = {2020},
	eissn = {1424-3911},
	pages = {608-616},
	orcid-numbers = {Mosztbacher, Dóra/0000-0002-2446-9247; Borbásné Farkas, Kornélia/0000-0002-5349-6527; Szentesi, Andrea Ildikó/0000-0003-2097-6927; Sarlós, Patrícia/0000-0002-5086-9455; Czimmer, József/0000-0001-7831-3523; Vincze, Áron/0000-0003-2217-7686; Erőss, Bálint Mihály/0000-0003-3658-8427; Czakó, László/0000-0002-6331-0802; Németh, Balázs/0000-0001-5338-7577; Papp, Mária/0000-0003-3662-4010; Dubravcsik, Zsolt/0000-0002-7231-3300; Márta, Katalin/0000-0002-2213-4865; Pécsi, Dániel/0000-0003-0499-6004; Szakács, Zsolt/0000-0002-7035-941X; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31627571,
	title = {Antibiotic therapy in acute pancreatitis: from global overuse to evidence based recommendations},
	url = {https://m2.mtmt.hu/api/publication/31627571},
	author = {Párniczky, Andrea and Lantos, Tamás and Tóth, Eszter Margit and Szakács, Zsolt and Gódi, Szilárd and Hágendorn, Roland and Illés, Dóra and Koncz, Balázs and Márta, Kata and Mikó, Alexandra and Mosztbacher, Dora and Németh, Balázs and Pécsi, Dániel and Szabó, Anikó and Szűcs, Ákos and Varjú, Péter and Szentesi, Andrea and Darvasi, Erika and Erőss, Bálint and Izbéki, Ferenc and Gajdán, László and Szabó-Halász, Adrienn and Vincze, Aron and Szabó, Imre and Pár, Gabriella and Bajor, Judit and Sarlós, Patrícia and Czimmer, József and Hamvas, József and Takács, Tamás and Szepes, Zoltán and Czakó, László and Varga, Márta and Novák, János and Bod, Barnabás and Szepes, Attila and Sümegi, János and Papp, Mária and Góg, Csaba and Török, Imola and Huang, Wei and Xia, Qing and Xue, Ping and Li, Weiqin and Chen, Weiwei and Shirinskaya, Natalia V. and Poluektov, Vladimir L. and Shirinskaya, Anna V. and Hegyi, Péter and Bátovsky, Marian and Rodriguez-Oballe, Juan A. and Salas, Isabel Miguel and Lopez-Diaz, Javier and Dominguez-Munoz, J Enrique and Molero, Xavier and Pando, Elizabeth and Ruiz-Rebollo, Maria Lourdes and Burgueño-Gómez, Beatriz and Chang, Yu-Ting and Chang, Ming-Chu and Sud, Ajay and Moore, Danielle and Sutton, Robert and Gougol, Amir and Papachristou, Georgios and Susak, Yaroslav Mykhailovych and Tiuliukin, Illia Olehovych and Gomes, António P. and Oliveira, Maria Jesus and Aparício, Davis Joao and Tantau, Marcell and Kurti, Floreta and Kovacheva-Slavova, Mila and Strecher, Stephanie-Susanne and Mayerle, Julia and Poporat, Goran and Das, Kshaunish and Marino, Marco Vito and Capurso, Gabriele and Małecka-Panas, Ewa and Zatorski, Hubert and Gasiorowska, Anita and Fabisiak, Natalia and Ceranowicz, Piotr and Kuśnierz-Cabala, Beata and Carvalho, Johana Rita and Fernandes, Samuel Raimundo and Chang, Jae Hyuck and Choi, Eun Kwang and Han, Jimin and Bertilsson, Sara and Jumaa, Hanaz and Sandblom, Gabriel and Kacar, Sabite and Baltatzis, Minas and Varabei, Aliaksandr Vladimir and Yeshi, Vizhynis and Chooklin, Serge and Kozachenko, Andriy and Veligotsky, Nikolay and Hegyi, Péter},
	doi = {10.1016/j.pan.2019.05.401},
	journal-iso = {PANCREATOLOGY},
	journal = {PANCREATOLOGY},
	volume = {19},
	unique-id = {31627571},
	issn = {1424-3903},
	year = {2019},
	eissn = {1424-3911},
	pages = {S148-S150},
	orcid-numbers = {Szakács, Zsolt/0000-0002-7035-941X; Németh, Balázs/0000-0001-5338-7577; Izbéki, Ferenc/0000-0001-7767-4319; Szepes, Zoltán/0000-0002-9466-8719; Czakó, László/0000-0002-6331-0802; Hegyi, Péter/0000-0003-0399-7259}
}

@article{MTMT:31627542,
	title = {A Multicenter, International Cohort Analysis of 1435 Patients to Support Clinical Trial Design in Acute Pancreatitis},
	url = {https://m2.mtmt.hu/api/publication/31627542},
	author = {Erőss, Bálint and Farkas, Nelli and Hanák, Lilla and Mikó, Alexandra and Vincze, Aron and Gódi, Szilárd and Sarlós, Patrícia and Czimmer, József and Bajor, Judit and Pécsi, Dániel and Varjú, Péter and Márta, Kata and Hegyi, Péter and Szentesi, Andrea and Párniczky, Andrea and Hamvas, József and Bod, Barnabás and Török, Imola and Hunor-Pál, Farkas and Izbéki, Ferenc and Szabó-Halász, Adrienn and Dunás, Veronika and Gajdán, László and Czakó, László and Illés, Dóra and Takács, Tamás and Németh, Balázs and Kui, Balázs and Darvasi, Erika and Papp, Mária and Földi, Ildikó and Fehér, Eszter and Varga, Márta and Csefkó, Klára and Novák, János and Sümegi, János and Szepes, Attila and Mickevicius, Artautas and Maldonado, Elena Ramirez and Sallinen, Ville and Ince, Ali Tüzün and Galeev, Shamil and Pencik, Petr and Hegyi, Péter},
	doi = {10.1016/j.pan.2019.05.399},
	journal-iso = {PANCREATOLOGY},
	journal = {PANCREATOLOGY},
	volume = {19},
	unique-id = {31627542},
	issn = {1424-3903},
	year = {2019},
	eissn = {1424-3911},
	pages = {S147-S148},
	orcid-numbers = {Czakó, László/0000-0002-6331-0802; Németh, Balázs/0000-0001-5338-7577; Hegyi, Péter/0000-0003-0399-7259}
}