@article{MTMT:34483970,
	title = {Points of Interest in the Chemistry of the Levomepromazine Drug Substance: Recycling of Undesired Enantiomer, Identification of New Phenothiazine Dimers, Synthesis of a Pharmacopeial Impurity, and an Unexpected Rearrangement},
	url = {https://m2.mtmt.hu/api/publication/34483970},
	author = {Poszávácz, László and Porcs-Makkay, Márta and Halász, Judit and Mórász, Tamás and Nagy, Tamás and Kátainé Fadgyas, Katalin and Simig, Gyula and Volk, Balázs},
	doi = {10.1021/acs.oprd.3c00368},
	journal-iso = {ORG PROCESS RES DEV},
	journal = {ORGANIC PROCESS RESEARCH & DEVELOPMENT},
	volume = {28},
	unique-id = {34483970},
	issn = {1083-6160},
	year = {2024},
	eissn = {1520-586X},
	pages = {281-292},
	orcid-numbers = {Simig, Gyula/0000-0002-2569-6476; Volk, Balázs/0000-0002-2019-1874}
}

@article{MTMT:33585454,
	title = {New, scalable process for the preparation of 5-acetyl-1H-pyrazole-3-carboxylic acid, a key intermediate of darolutamide},
	url = {https://m2.mtmt.hu/api/publication/33585454},
	author = {Poszávácz, László and Nagy, Tamás and Kátainé Fadgyas, Katalin and Volk, Balázs},
	doi = {10.1055/a-2016-4337},
	journal-iso = {SYNTHESIS-STUTTGART},
	journal = {SYNTHESIS-STUTTGART},
	volume = {55},
	unique-id = {33585454},
	issn = {0039-7881},
	abstract = {A new, efficient process for the synthesis of 5-acetyl-1H-pyrazole-3-carboxylic acid, a versatile building block and the key intermediate of darolutamide, using diethyl pyrazole-3,5-dicarboxylate as the starting material is described. Contrary to the synthetic routes known from the literature, this procedure does not apply explosive diazo reagents, moreover it is simple and safe, thereby suitable for scale-up.},
	year = {2023},
	eissn = {1437-210X},
	pages = {2061-2069},
	orcid-numbers = {Volk, Balázs/0000-0002-2019-1874}
}

@misc{MTMT:33106229,
	title = {„Semmi sem olyan egyszerű, mint amilyennek látszik”. Darolutamid intermedier generikus szemmel},
	url = {https://m2.mtmt.hu/api/publication/33106229},
	author = {Poszávácz, László and Szilágyi, Bence and Nagy, Tamás and Egyed, Attila and Kátainé Fadgyas, Katalin and Keserű, György Miklós and Mándity, István and Volk, Balázs},
	unique-id = {33106229},
	year = {2022},
	orcid-numbers = {Mándity, István/0000-0003-2865-6143; Volk, Balázs/0000-0002-2019-1874}
}

@article{MTMT:33685230,
	title = {Crystalline form of 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid},
	url = {https://m2.mtmt.hu/api/publication/33685230},
	author = {Hunyadi, Dávid and Poszávácz, László},
	journal-iso = {IP DOT COM JOURNAL},
	journal = {THE IP.COM JOURNAL},
	unique-id = {33685230},
	issn = {1533-0001},
	year = {2018}
}

@{MTMT:3102668,
	title = {Quinazoline derivatives, process for the preparation thereof and pharmaceutical compositions comprising the same},
	url = {https://m2.mtmt.hu/api/publication/3102668},
	author = {Gacsályi, István and Bózsing, D and Kertész, Sz and Megyeri, K and Barkóczy, J and Molnárné Samu, Erika and Poszávácz, László and Antoni, Ferenc András and Volk, Balázs},
	unique-id = {3102668},
	year = {2015},
	orcid-numbers = {Volk, Balázs/0000-0002-2019-1874}
}

@article{MTMT:1846147,
	title = {Optimization of (Arylpiperazinylbutyl)oxindoles Exhibiting Selective 5-HT(7) Receptor Antagonist Activity},
	url = {https://m2.mtmt.hu/api/publication/1846147},
	author = {Volk, Balázs and Gacsályi, István and Pallagi, Katalin and Poszávácz, László and Gyönös, Ildikó and Szabó, Éva and Bakó, Tibor and Spedding, M and Simig, Gyula and Szénási, Gábor},
	doi = {10.1021/jm200547z},
	journal-iso = {J MED CHEM},
	journal = {JOURNAL OF MEDICINAL CHEMISTRY},
	volume = {54},
	unique-id = {1846147},
	issn = {0022-2623},
	abstract = {A series of (arylpiperazinylbutyl)oxindoles as highly potent 5-HT(7) receptor antagonists has been studied for their selectivity toward the 5-HT(1A) receptor and alpha(1)-adrenoceptor. Several derivatives exhibited high 5-HT(7)/5-HT(1A) selectivity, and the key structural factors for reducing undesired alpha(1)-adrenergic receptor binding have also been identified. Rapid metabolism, a common problem within this family of compounds, could be circumvented with appropriate substitution patterns on the oxindole carbocycle. Contrary to expectations, none of the compounds produced an antidepressant-like action in the forced swimming test in mice despite sufficiently high brain concentrations. On the other hand, certain analogues showed significant anxiolytic activity in two different animal models: the Vogel conflict drinking test in rats and the light-dark test in mice.},
	keywords = {DERIVATIVES; AGENTS; RAT HYPOTHALAMUS; HIGH-AFFINITY; LIGANDS; MEDICINAL CHEMISTRY; CONFORMATIONALLY CONSTRAINED ANALOGS; forced swimming test; SEROTONIN RECEPTORS; 5-HYDROXYTRYPTAMINE(7) RECEPTOR},
	year = {2011},
	eissn = {1520-4804},
	pages = {6657-6669},
	orcid-numbers = {Volk, Balázs/0000-0002-2019-1874; Simig, Gyula/0000-0002-2569-6476; Szénási, Gábor/0000-0002-7350-6091}
}

@misc{MTMT:33706675,
	title = {Novel Synthesis of Naratriptan via N-benzyl-indole-5-carbaldehyde},
	url = {https://m2.mtmt.hu/api/publication/33706675},
	author = {Poszávácz, László and Bertha, Ferenc and Simig, Gyula and Fetter, József},
	unique-id = {33706675},
	year = {2009},
	orcid-numbers = {Simig, Gyula/0000-0002-2569-6476}
}

@misc{MTMT:33706660,
	title = {Központi idegrendszerre ható izokinolinok szintézise},
	url = {https://m2.mtmt.hu/api/publication/33706660},
	author = {Domán, I. and Poszávácz, László and Barkóczy, József and Simig, Gyula},
	unique-id = {33706660},
	year = {2008},
	orcid-numbers = {Simig, Gyula/0000-0002-2569-6476}
}

@{MTMT:33682682,
	title = {Indolszármazékok mint gyógyszeripari közbenső termékek},
	url = {https://m2.mtmt.hu/api/publication/33682682},
	author = {Barkóczy, József and Bertha, Ferenc and Fetter, József and Poszávácz, László and Simig, Gyula},
	unique-id = {33682682},
	year = {2007},
	orcid-numbers = {Simig, Gyula/0000-0002-2569-6476}
}

@misc{MTMT:33706640,
	title = {New Synthesis of Naratriptan},
	url = {https://m2.mtmt.hu/api/publication/33706640},
	author = {Poszávácz, László and Fetter, József and Bertha, Ferenc and Simig, Gyula},
	unique-id = {33706640},
	year = {2006},
	orcid-numbers = {Simig, Gyula/0000-0002-2569-6476}
}