TY - JOUR AU - Szőke, Anita AU - Sárkány, Orsolya AU - Schermann, Géza AU - Kapuy, Orsolya AU - Diernfellner, Axel C R AU - Brunner, Michael AU - Gyöngyösi, Norbert AU - Káldi, Krisztina TI - Adaptation to glucose starvation is associated with molecular reorganization of the circadian clock in Neurospora crassa. JF - ELIFE J2 - ELIFE VL - 12 PY - 2023 PG - 26 SN - 2050-084X DO - 10.7554/eLife.79765 UR - https://m2.mtmt.hu/api/publication/33552513 ID - 33552513 AB - The circadian clock governs rhythmic cellular functions by driving the expression of a substantial fraction of the genome and thereby significantly contributes to the adaptation to changing environmental conditions. Using the circadian model organism Neurospora crassa, we show that molecular timekeeping is robust even under severe limitation of carbon sources, however, stoichiometry, phosphorylation and subcellular distribution of the key clock components display drastic alterations. Protein kinase A, protein phosphatase 2 A and glycogen synthase kinase are involved in the molecular reorganization of the clock. RNA-seq analysis reveals that the transcriptomic response of metabolism to starvation is highly dependent on the positive clock component WC-1. Moreover, our molecular and phenotypic data indicate that a functional clock facilitates recovery from starvation. We suggest that the molecular clock is a flexible network that allows the organism to maintain rhythmic physiology and preserve fitness even under long-term nutritional stress. LA - English DB - MTMT ER - TY - JOUR AU - Révész, Fruzsina AU - M Tóth, Erika AU - Kriszt, Balázs AU - Bóka, Károly AU - Benedek, Tibor AU - Sárkány, Orsolya AU - Nagy, Zsuzsa AU - Táncsics, András TI - Sphingobium aquiterrae sp. nov., a toluene, meta- and para-xylene-degrading bacterium isolated from petroleum hydrocarbon-contaminated groundwater JF - INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY J2 - INT J SYST EVOL MICR VL - 68 PY - 2018 IS - 9 SP - 2807 EP - 2812 PG - 6 SN - 1466-5026 DO - 10.1099/ijsem.0.002898 UR - https://m2.mtmt.hu/api/publication/3392257 ID - 3392257 AB - A Gram-negative, aerobic, slightly yellow-pigmented bacterium, designated as SKLS-A10(T), was isolated from groundwater sample of the 'Siklos' petroleum hydrocarbon contaminated site (Hungary). Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain SKLS-A10(T) formed a distinct phyletic lineage within the genus Sphingobium. It shared the highest 16S rRNA gene homology with Sphingobium abikonense DSM 23268(T) (97.29 %), followed by Sphingobium lactosutens DSM 23389(T) (97.23 %), Sphingobium phenoxybenzoativorans KCTC 42448(T) (97.16 %) and Sphingobium subterraneum NBRC 109814(T) (96.74 %). The predominant fatty acids (> 5% of the total) are C-18 : (1)omega 7c, C-14 : (0) 2-OH, C-16 : (1)omega 7c/iso C-15 (:) (0) 2-OH, C-17 (:) (1)omega 6c and C-16 : 0. The major ubiquinone is Q-10. The predominant polyamine is spermidine. The major polar lipids are sphingoglycolipid and diphosphatidylglycerol. The DNA G+C content of strain SKLS-A10(T) is 65.9 mol%. On the basis of evidence from this taxonomic study using a polyphasic approach, strain SKLS-A10(T) represents a novel species of the genus Sphingobium for which the name Sphingobium aquiterrae sp. nov. is proposed. The type strain is SKLS-A10(T) (=DSM 106441(T)=NCAIM B. 02634(T)). LA - English DB - MTMT ER - TY - CONF AU - Szuróczki, Sára AU - Sárkány, Orsolya AU - Toumi, Marwene AU - Kazzazi, Latifa AU - M Tóth, Erika ED - Máthé, István TI - Novel bacterial taxa isolated from the water of Lake Fertő. A Fertő vizéből izolált új baktérium taxonok polifázikus vizsgálata TS - A Fertő vizéből izolált új baktérium taxonok polifázikus vizsgálata T2 - A Kárpát-medence vizes élőhelyei: Új microbafajot és új biotechnolológiai lehetősége forrásai = Aquatic habitats of the Carpathian Basin: Sources of new microbial species and new biotechnological potential PY - 2018 SP - 26 EP - 28 PG - 3 UR - https://m2.mtmt.hu/api/publication/3373273 ID - 3373273 LA - English DB - MTMT ER - TY - JOUR AU - Szuróczki, Sára AU - Sárkány, Orsolya AU - Sári, Eszter AU - Márialigeti, Károly AU - M Tóth, Erika TI - Study of bacterial strains isolated from Fertő: carbon source utilization tests and detection of novel taxa JF - ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA J2 - ACTA MICROBIOL IMMUNOL HUNG VL - 64 PY - 2017 IS - supplement 1 SP - 176 EP - 176 PG - 1 SN - 1217-8950 UR - https://m2.mtmt.hu/api/publication/3297917 ID - 3297917 LA - English DB - MTMT ER -