@article{MTMT:33552513, title = {Adaptation to glucose starvation is associated with molecular reorganization of the circadian clock in Neurospora crassa.}, url = {https://m2.mtmt.hu/api/publication/33552513}, author = {Szőke, Anita and Sárkány, Orsolya and Schermann, Géza and Kapuy, Orsolya and Diernfellner, Axel C R and Brunner, Michael and Gyöngyösi, Norbert and Káldi, Krisztina}, doi = {10.7554/eLife.79765}, journal-iso = {ELIFE}, journal = {ELIFE}, volume = {12}, unique-id = {33552513}, issn = {2050-084X}, abstract = {The circadian clock governs rhythmic cellular functions by driving the expression of a substantial fraction of the genome and thereby significantly contributes to the adaptation to changing environmental conditions. Using the circadian model organism Neurospora crassa, we show that molecular timekeeping is robust even under severe limitation of carbon sources, however, stoichiometry, phosphorylation and subcellular distribution of the key clock components display drastic alterations. Protein kinase A, protein phosphatase 2 A and glycogen synthase kinase are involved in the molecular reorganization of the clock. RNA-seq analysis reveals that the transcriptomic response of metabolism to starvation is highly dependent on the positive clock component WC-1. Moreover, our molecular and phenotypic data indicate that a functional clock facilitates recovery from starvation. We suggest that the molecular clock is a flexible network that allows the organism to maintain rhythmic physiology and preserve fitness even under long-term nutritional stress.}, keywords = {Chromosomes; circadian rhythm; Gene Expression; Protein Phosphatase 2; CELL BIOLOGY; Transcriptome; protein kinase A; Neurospora; White Collar complex; glucose starvation; N. crassa}, year = {2023}, eissn = {2050-084X}, orcid-numbers = {Szőke, Anita/0000-0003-0593-2088; Kapuy, Orsolya/0000-0002-8484-4504; Káldi, Krisztina/0000-0002-5724-0182} } @article{MTMT:3392257, title = {Sphingobium aquiterrae sp. nov., a toluene, meta- and para-xylene-degrading bacterium isolated from petroleum hydrocarbon-contaminated groundwater}, url = {https://m2.mtmt.hu/api/publication/3392257}, author = {Révész, Fruzsina and M Tóth, Erika and Kriszt, Balázs and Bóka, Károly and Benedek, Tibor and Sárkány, Orsolya and Nagy, Zsuzsa and Táncsics, András}, doi = {10.1099/ijsem.0.002898}, journal-iso = {INT J SYST EVOL MICR}, journal = {INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY}, volume = {68}, unique-id = {3392257}, issn = {1466-5026}, abstract = {A Gram-negative, aerobic, slightly yellow-pigmented bacterium, designated as SKLS-A10(T), was isolated from groundwater sample of the 'Siklos' petroleum hydrocarbon contaminated site (Hungary). Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain SKLS-A10(T) formed a distinct phyletic lineage within the genus Sphingobium. It shared the highest 16S rRNA gene homology with Sphingobium abikonense DSM 23268(T) (97.29 %), followed by Sphingobium lactosutens DSM 23389(T) (97.23 %), Sphingobium phenoxybenzoativorans KCTC 42448(T) (97.16 %) and Sphingobium subterraneum NBRC 109814(T) (96.74 %). The predominant fatty acids (> 5% of the total) are C-18 : (1)omega 7c, C-14 : (0) 2-OH, C-16 : (1)omega 7c/iso C-15 (:) (0) 2-OH, C-17 (:) (1)omega 6c and C-16 : 0. The major ubiquinone is Q-10. The predominant polyamine is spermidine. The major polar lipids are sphingoglycolipid and diphosphatidylglycerol. The DNA G+C content of strain SKLS-A10(T) is 65.9 mol%. On the basis of evidence from this taxonomic study using a polyphasic approach, strain SKLS-A10(T) represents a novel species of the genus Sphingobium for which the name Sphingobium aquiterrae sp. nov. is proposed. The type strain is SKLS-A10(T) (=DSM 106441(T)=NCAIM B. 02634(T)).}, keywords = {GROUNDWATER; BTEX; Sphingobium}, year = {2018}, eissn = {1466-5034}, pages = {2807-2812}, orcid-numbers = {M Tóth, Erika/0000-0001-9048-5758; Bóka, Károly/0000-0002-1324-3592} } @CONFERENCE{MTMT:3373273, title = {Novel bacterial taxa isolated from the water of Lake Fertő. A Fertő vizéből izolált új baktérium taxonok polifázikus vizsgálata}, url = {https://m2.mtmt.hu/api/publication/3373273}, author = {Szuróczki, Sára and Sárkány, Orsolya and Toumi, Marwene and Kazzazi, Latifa and M Tóth, Erika}, booktitle = {A Kárpát-medence vizes élőhelyei: Új microbafajot és új biotechnolológiai lehetősége forrásai = Aquatic habitats of the Carpathian Basin: Sources of new microbial species and new biotechnological potential}, unique-id = {3373273}, year = {2018}, pages = {26-28}, orcid-numbers = {M Tóth, Erika/0000-0001-9048-5758} } @article{MTMT:3297917, title = {Study of bacterial strains isolated from Fertő: carbon source utilization tests and detection of novel taxa}, url = {https://m2.mtmt.hu/api/publication/3297917}, author = {Szuróczki, Sára and Sárkány, Orsolya and Sári, Eszter and Márialigeti, Károly and M Tóth, Erika}, journal-iso = {ACTA MICROBIOL IMMUNOL HUNG}, journal = {ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA}, volume = {64}, unique-id = {3297917}, issn = {1217-8950}, year = {2017}, eissn = {1588-2640}, pages = {176-176}, orcid-numbers = {Márialigeti, Károly/0000-0003-1536-5160; M Tóth, Erika/0000-0001-9048-5758} }