@article{MTMT:32172268,
	title = {The effect of mild traumatic brain injury on cerebral microbleeds in aging},
	url = {https://m2.mtmt.hu/api/publication/32172268},
	author = {Tóth, Luca and Czigler, András and Horváth, Péter and Szarka, Nikolett and Környei, Bálint Soma and Tóth, Arnold and Schwarcz, Attila and Ungvári, Zoltán István and Büki, András and Tóth, Péter József},
	doi = {10.3389/fnagi.2021.717391},
	journal-iso = {FRONT AGING NEUROSCI},
	journal = {FRONTIERS IN AGING NEUROSCIENCE},
	volume = {13},
	unique-id = {32172268},
	issn = {1663-4365},
	abstract = {A traumatic brain injury (TBI) induces the formation of cerebral microbleeds (CMBs), which are associated with cognitive impairments, psychiatric disorders, and gait dysfunctions in patients. Elderly people frequently suffer TBIs, especially mild brain trauma (mTBI). Interestingly, aging is also an independent risk factor for the development of CMBs. However, how TBI and aging may interact to promote the development of CMBs is not well established. In order to test the hypothesis that an mTBI exacerbates the development of CMBs in the elderly, we compared the number and cerebral distribution of CMBs and assessed them by analysing susceptibility weighted (SW) MRI in young (25 ± 10 years old, n = 18) and elder (72 ± 7 years old, n = 17) patients after an mTBI and in age-matched healthy subjects (young: 25 ± 6 years old, n = 20; aged: 68 ± 5 years old, n = 23). We found significantly more CMBs in elder patients after an mTBI compared with young patients; however, we did not observe a significant difference in the number of cerebral microhemorrhages between aged and aged patients with mTBI. The majority of CMBs were found supratentorially (lobar and basal ganglion). The lobar distribution of supratentorial CMBs showed that aging enhances the formation of parietal and occipital CMBs after mTBIs. This suggests that aging and mTBIs do not synergize in the induction of the development of CMBs, and that the different distribution of mTBI-induced CMBs in aged patients may lead to specific age-related clinical characteristics of mTBIs.},
	year = {2021},
	eissn = {1663-4365},
	orcid-numbers = {Ungvári, Zoltán István/0000-0002-6035-6039}
}

@article{MTMT:31954808,
	title = {Provocation and prediction of visual peripersonal neglect-like symptoms in preoperative planning and during awake brain surgery},
	url = {https://m2.mtmt.hu/api/publication/31954808},
	author = {Tamás, Viktória and Sebestyén, Gabriella and Nagy, Szilvia Anett and Horváth, Péter and Mérei, Ákos and Tomaiuolo, Francesco and Raffa, Giovanni and Germanó, Antonino Francesco and Büki, András},
	doi = {10.1007/s00701-021-04822-2},
	journal-iso = {ACTA NEUROCHIR},
	journal = {ACTA NEUROCHIRURGICA},
	volume = {163},
	unique-id = {31954808},
	issn = {0001-6268},
	abstract = {Neglect is a severe neuropsychological/neurological deficit that usually develops due to lesions of the posterior inferior parietal area of the right hemisphere and is characterized by a lack of attention to the left side. Our case is a proven right-handed, 30-year-old female patient with a low-grade glioma, which was located in the temporo-opercular region and also in the superior temporal gyrus of the right hemisphere. Upon presurgical planning, the motor, language, and visuospatial functions were mapped. In order to achieve this, the protocol for routine magnetic resonance imaging and navigated transcranial magnetic stimulation has been expanded, accordingly.},
	keywords = {brain tumor; visual neglect; nTMS; awake brain surgery},
	year = {2021},
	eissn = {0942-0940},
	pages = {1941-1947},
	orcid-numbers = {Nagy, Szilvia Anett/0000-0001-6483-9209}
}

@article{MTMT:31620181,
	title = {Traumatic brain injury-induced cerebral microbleeds in the elderly},
	url = {https://m2.mtmt.hu/api/publication/31620181},
	author = {Tóth, Luca and Czigler, András and Horváth, Péter and Környei, Bálint Soma and Szarka, Nikolett and Schwarcz, Attila and Ungvári, Zoltán István and Büki, András and Tóth, Péter József},
	doi = {10.1007/s11357-020-00280-3},
	journal-iso = {GEROSCIENCE},
	journal = {GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)},
	volume = {43},
	unique-id = {31620181},
	issn = {2509-2715},
	abstract = {Traumatic brain injury (TBI) was shown to lead to the development of cerebral microbleeds (CMBs), which are associated with long term cognitive decline and gait disturbances in patients. The elderly is one of the most vulnerable parts of the population to suffer TBI. Importantly, ageing is known to exacerbate microvascular fragility and to promote the formation of CMBs. In this overview, the effect of ageing is discussed on the development and characteristics of TBI-related CMBs, with special emphasis on CMBs associated with mild TBI. Four cases of TBI-related CMBs are described to illustrate the concept that ageing exacerbates the deleterious microvascular effects of TBI and that similar brain trauma may induce more CMBs in old patients than in young ones. Recommendations are made for future prospective studies to establish the mechanistic effects of ageing on the formation of CMBs after TBI, and to determine long-term consequences of CMBs on clinically relevant outcome measures including cognitive performance, gait and balance function.},
	keywords = {Mild traumatic brain injury; Ageing; Brain trauma; Microbleed; Vascular changes; Cerebral microhaemorrhage},
	year = {2021},
	eissn = {2509-2723},
	pages = {125-136},
	orcid-numbers = {Ungvári, Zoltán István/0000-0002-6035-6039}
}

@{MTMT:33740792,
	title = {Acute emergency management of traumatic brain injury},
	url = {https://m2.mtmt.hu/api/publication/33740792},
	author = {Horváth, Péter and Verma, K. and Valadka, A.B.},
	booktitle = {Brain Injury Medicine: Board Review},
	doi = {10.1016/B978-0-323-65385-5.00019-6},
	unique-id = {33740792},
	year = {2020},
	pages = {84and88.e1}
}

@article{MTMT:3262835,
	title = {Baleseti agysérültek ellátásának irányelvei - 2017},
	url = {https://m2.mtmt.hu/api/publication/3262835},
	author = {Büki, András and Barzó, Pál and Demeter, B and Kanizsai, Péter László and Ezer, Erzsébet and Tóth, Péter József and Horváth, Péter and Varga, Csaba},
	doi = {10.18071/isz.70.0223},
	journal-iso = {IDEGGYOGY SZEMLE},
	journal = {IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE},
	volume = {70},
	unique-id = {3262835},
	issn = {0019-1442},
	keywords = {Neurotrauma; Irányelvek; agysérülés; koponyasérülés; bizonyítékon alapuló orvoslás},
	year = {2017},
	eissn = {2498-6208},
	pages = {223-245},
	orcid-numbers = {Barzó, Pál/0000-0001-8717-748X; Kanizsai, Péter László/0000-0001-7896-2857}
}

@article{MTMT:3195505,
	title = {HYPERTENSION-INDUCED ENHANCED MYOGENIC CONSTRICTION OF CEREBRAL ARTERIES IS PRESERVED AFTER TRAUMATIC BRAIN INJURY.},
	url = {https://m2.mtmt.hu/api/publication/3195505},
	author = {Szarka, Nikolett and Amrein, Krisztina and Horváth, Péter and Ivic, Ivan and Czeiter, Endre and Büki, András and Koller, Ákos and Tóth, Péter József},
	doi = {10.1089/neu.2016.4962},
	journal-iso = {J NEUROTRAUM},
	journal = {JOURNAL OF NEUROTRAUMA},
	volume = {34},
	unique-id = {3195505},
	issn = {0897-7151},
	abstract = {Traumatic brain injury (TBI) was shown to impair pressure-induced myogenic response of cerebral arteries, which is associated with vascular and neural dysfunction and increased mortality of TBI patients. Hypertension was shown to enhance myogenic tone of cerebral arteries via increased vascular production of 20-hydroxyeicosatrienoic acid (HETE). This adaptive mechanism protects brain tissue form pressure/volume overload, but it can also lead to increased susceptibility to cerebral ischemia. Although both effects may potentiate the detrimental vascular consequences of TBI, it is not known how hypertension modulates the effect of TBI on myogenic responses of cerebral vessels. We hypothesized that in hypertensive rats, the enhanced myogenic cerebrovascular response is preserved after TBI. Thus, we investigated the myogenic responses of isolated middle cerebral arteries (MCA) of normotensive and spontaneously hypertensive rats (SHR) after severe impact acceleration diffuse brain injury. TBI diminished myogenic constriction of MCAs isolated from normotensive rats, whereas the 20-HETE-mediated enhanced myogenic response of MCAs isolated from SHRs was not affected by TBI. These results suggest that the optimal cerebral perfusion pressure values and vascular signaling pathways can be different and thus should be targeted differently in normotensive and hypertensive patients following TBI.},
	keywords = {BLOOD-FLOW; INHIBITOR; CA2+; RATS; EPIDEMIOLOGY; AUTOREGULATION; AUTOREGULATION; cerebral blood flow; Clinical Neurology; Critical Care Medicine; 20-HETE; 20-HETE; SEVERE HEAD-INJURY; Oxidative stress},
	year = {2017},
	eissn = {1557-9042},
	pages = {2315-2319},
	orcid-numbers = {Czeiter, Endre/0000-0002-9578-6944; Koller, Ákos/0000-0003-3256-8701}
}