TY  - THES
AU  - Nagy, Éva
TI  - A SARS-CoV-2 járvány első négy járványhullámának epidemiológiai jellemzése, valamint a COVID-19 súlyosságát és mortalitását befolyásoló rizikótényezők hatásának vizsgálata
PY  - 2023
DO  - 10.14753/SE.2023.2888
UR  - https://m2.mtmt.hu/api/publication/34581541
ID  - 34581541
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Éva
AU  - Golopencza, Péter
AU  - Barcs, István
AU  - Ludwig, Endre
TI  - Comparison of COVID-19 Severity and Mortality Rates in the First Four Epidemic Waves in Hungary in a Single-Center Study with Special Regard to Critically Ill Patients in an Intensive Care Unit
JF  - TROPICAL MEDICINE AND INFECTIOUS DISEASE
J2  - TROP MED INFECT DISEASES
VL  - 8
PY  - 2023
IS  - 3
PG  - 15
SN  - 2414-6366
DO  - 10.3390/tropicalmed8030153
UR  - https://m2.mtmt.hu/api/publication/33676062
ID  - 33676062
AB  - Different variants of coronavirus 2 (SARS-CoV-2), a virus responsible for severe acute respiratory syndrome, caused several epidemic surges in Hungary. The severity of these surges varied due to the different virulences of the variants. In a single-center, retrospective, observational study, we aimed to assess and compare morbidities and mortality rates across the epidemic waves I to IV with special regard to hospitalized, critically ill patients. A significant difference was found between the surges with regard to morbidity (p < 0.001) and ICU mortality (p = 0.002), while in-hospital mortality rates (p = 0.503) did not differ significantly. Patients under invasive ventilation had a higher incidence of bloodstream infection (aOR: 8.91 [4.43–17.95] p < 0.001), which significantly increased mortality (OR: 3.32 [2.01–5.48]; p < 0.001). Our results suggest that Waves III and IV, caused by the alpha (B.1.1.7) and delta (B.1.617.2) variants, respectively, were more severe in terms of morbidity. The incidence of bloodstream infection was high in critically ill patients. Our results suggest that clinicians should be aware of the risk of bloodstream infection in critically ill ICU patients, especially when invasive ventilation is used.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Éva
AU  - Cseh, Viktória
AU  - Barcs, István
AU  - Ludwig, Endre
TI  - The Impact of Comorbidities and Obesity on the Severity and Outcome of COVID-19 in Hospitalized Patients—A Retrospective Study in a Hungarian Hospital
JF  - INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
J2  - INT J ENV RES PUB HE
VL  - 20
PY  - 2023
PG  - 15
SN  - 1661-7827
DO  - 10.3390/ijerph20021372
UR  - https://m2.mtmt.hu/api/publication/33563258
ID  - 33563258
N1  - Export Date: 26 April 2023            
            Correspondence Address: Nagy, É.; Schools of PhD Studies, Hungary; email: evanagy1025@gmail.com
AB  - Patients with comorbidities and obesity are more likely to be hospitalized with coronavirus disease 2019 (COVID-19), to have a higher incidence of severe pneumonia and to also show higher mortality rates. Between 15 March 2020 and 31 December 2021, a retrospective, single-center, observational study was conducted among patients requiring hospitalization for COVID-19 infection. Our aim was to investigate the impact of comorbidities and lifestyle risk factors on mortality, the need for intensive care unit (ICU) admission and the severity of the disease among these patients. Our results demonstrated that comorbidities and obesity increased the risk for all investigated endpoints. Age over 65 years and male sex were identified as independent risk factors, and cardiovascular diseases, cancer, endocrine and metabolic diseases, chronic kidney disease and obesity were identified as significant risk factors. Obesity was found to be the most significant risk factor, associated with considerable odds of COVID-19 mortality and the need for ICU admission in the under-65 age group (aOR: 2.95; p < 0.001 and aOR: 3.49, p < 0.001). In our study, risk factors that increased mortality and morbidity among hospitalized patients were identified. Detailed information on such factors may support therapeutic decision making, the proper targeting of vaccination campaigns and the effective overall management of the COVID-19 epidemic, hence reducing the burden on the healthcare system.
LA  - English
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Éva
AU  - Rákay, Erzsébet
AU  - Szabadka, Hajnalka
AU  - Barcs, István
TI  - A Bajcsy Kórház esete a Legionellával
JF  - IME
J2  - IME
VL  - 17
PY  - 2018
IS  - 3
SP  - 18
EP  - 22
PG  - 5
SN  - 1588-6387
UR  - https://m2.mtmt.hu/api/publication/3372654
ID  - 3372654
LA  - Hungarian
DB  - MTMT
ER  - 

TY  - JOUR
AU  - Nagy, Éva
AU  - Higyisán, Ilona
AU  - Kálmán, Zsuzsa
AU  - Barcs, István
TI  - Vancomycin-rezisztens Enterococcus fertőzések a Bajcsy-Zsilinszky Kórházban
JF  - IME
J2  - IME
VL  - 15
PY  - 2016
IS  - 9
SP  - 26
EP  - 32
PG  - 7
SN  - 1588-6387
UR  - https://m2.mtmt.hu/api/publication/3236640
ID  - 3236640
AB  - A magyarországi adatokkal egybehangzóan, a Bajcsy-Zsilinszky Kórházban is évről évre egyre több vancomycin rezisztens Enterococcus (VRE) fertőzést regisztrálunk. Glikopeptidekkel szembeni rezisztencia esetén a terápiás lehetőségek beszűkülnek, az általuk okozott kórképek pedig nem ritkán súlyos kimenetelűek. A multirezisztens kórokozók (MRK) között felzárkózóban van a VRE, mely fontos intézkedéseket sürget a kórházi infekciókontroll terén. A korábbi években tapasztalt - a kórházunkban is endémiásnak tekinthető - nagyszámú meticillin rezisztens Staphylococcus aureus (MRSA) és Clostridium difficile infekciók (CDI) előfordulása miatt megnőtt a vancomycin felhasználás, ami viszont kedvez a VRE szelektálódásának.
LA  - Hungarian
DB  - MTMT
ER  -