@mastersthesis{MTMT:34581541, title = {A SARS-CoV-2 járvány első négy járványhullámának epidemiológiai jellemzése, valamint a COVID-19 súlyosságát és mortalitását befolyásoló rizikótényezők hatásának vizsgálata}, url = {https://m2.mtmt.hu/api/publication/34581541}, author = {Nagy, Éva}, doi = {10.14753/SE.2023.2888}, unique-id = {34581541}, year = {2023}, orcid-numbers = {Nagy, Éva/0000-0001-5988-0530} } @article{MTMT:33676062, title = {Comparison of COVID-19 Severity and Mortality Rates in the First Four Epidemic Waves in Hungary in a Single-Center Study with Special Regard to Critically Ill Patients in an Intensive Care Unit}, url = {https://m2.mtmt.hu/api/publication/33676062}, author = {Nagy, Éva and Golopencza, Péter and Barcs, István and Ludwig, Endre}, doi = {10.3390/tropicalmed8030153}, journal-iso = {TROP MED INFECT DISEASES}, journal = {TROPICAL MEDICINE AND INFECTIOUS DISEASE}, volume = {8}, unique-id = {33676062}, abstract = {Different variants of coronavirus 2 (SARS-CoV-2), a virus responsible for severe acute respiratory syndrome, caused several epidemic surges in Hungary. The severity of these surges varied due to the different virulences of the variants. In a single-center, retrospective, observational study, we aimed to assess and compare morbidities and mortality rates across the epidemic waves I to IV with special regard to hospitalized, critically ill patients. A significant difference was found between the surges with regard to morbidity (p < 0.001) and ICU mortality (p = 0.002), while in-hospital mortality rates (p = 0.503) did not differ significantly. Patients under invasive ventilation had a higher incidence of bloodstream infection (aOR: 8.91 [4.43–17.95] p < 0.001), which significantly increased mortality (OR: 3.32 [2.01–5.48]; p < 0.001). Our results suggest that Waves III and IV, caused by the alpha (B.1.1.7) and delta (B.1.617.2) variants, respectively, were more severe in terms of morbidity. The incidence of bloodstream infection was high in critically ill patients. Our results suggest that clinicians should be aware of the risk of bloodstream infection in critically ill ICU patients, especially when invasive ventilation is used.}, year = {2023}, eissn = {2414-6366}, orcid-numbers = {Nagy, Éva/0000-0001-5988-0530; Barcs, István/0000-0002-6025-4278} } @article{MTMT:33563258, title = {The Impact of Comorbidities and Obesity on the Severity and Outcome of COVID-19 in Hospitalized Patients—A Retrospective Study in a Hungarian Hospital}, url = {https://m2.mtmt.hu/api/publication/33563258}, author = {Nagy, Éva and Cseh, Viktória and Barcs, István and Ludwig, Endre}, doi = {10.3390/ijerph20021372}, journal-iso = {INT J ENV RES PUB HE}, journal = {INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, volume = {20}, unique-id = {33563258}, issn = {1661-7827}, abstract = {Patients with comorbidities and obesity are more likely to be hospitalized with coronavirus disease 2019 (COVID-19), to have a higher incidence of severe pneumonia and to also show higher mortality rates. Between 15 March 2020 and 31 December 2021, a retrospective, single-center, observational study was conducted among patients requiring hospitalization for COVID-19 infection. Our aim was to investigate the impact of comorbidities and lifestyle risk factors on mortality, the need for intensive care unit (ICU) admission and the severity of the disease among these patients. Our results demonstrated that comorbidities and obesity increased the risk for all investigated endpoints. Age over 65 years and male sex were identified as independent risk factors, and cardiovascular diseases, cancer, endocrine and metabolic diseases, chronic kidney disease and obesity were identified as significant risk factors. Obesity was found to be the most significant risk factor, associated with considerable odds of COVID-19 mortality and the need for ICU admission in the under-65 age group (aOR: 2.95; p < 0.001 and aOR: 3.49, p < 0.001). In our study, risk factors that increased mortality and morbidity among hospitalized patients were identified. Detailed information on such factors may support therapeutic decision making, the proper targeting of vaccination campaigns and the effective overall management of the COVID-19 epidemic, hence reducing the burden on the healthcare system.}, keywords = {MORTALITY; Hungary; OBESITY; disease severity; comorbidities; ICU admission; COVID-19; SARS-CoV-2}, year = {2023}, eissn = {1660-4601}, orcid-numbers = {Nagy, Éva/0000-0001-5988-0530; Barcs, István/0000-0002-6025-4278} } @article{MTMT:3372654, title = {A Bajcsy Kórház esete a Legionellával}, url = {https://m2.mtmt.hu/api/publication/3372654}, author = {Nagy, Éva and Rákay, Erzsébet and Szabadka, Hajnalka and Barcs, István}, journal-iso = {IME}, journal = {IME}, volume = {17}, unique-id = {3372654}, issn = {1588-6387}, year = {2018}, eissn = {1789-9974}, pages = {18-22}, orcid-numbers = {Nagy, Éva/0000-0001-5988-0530; Barcs, István/0000-0002-6025-4278} } @article{MTMT:3236640, title = {Vancomycin-rezisztens Enterococcus fertőzések a Bajcsy-Zsilinszky Kórházban}, url = {https://m2.mtmt.hu/api/publication/3236640}, author = {Nagy, Éva and Higyisán, Ilona and Kálmán, Zsuzsa and Barcs, István}, journal-iso = {IME}, journal = {IME}, volume = {15}, unique-id = {3236640}, issn = {1588-6387}, abstract = {A magyarországi adatokkal egybehangzóan, a Bajcsy-Zsilinszky Kórházban is évről évre egyre több vancomycin rezisztens Enterococcus (VRE) fertőzést regisztrálunk. Glikopeptidekkel szembeni rezisztencia esetén a terápiás lehetőségek beszűkülnek, az általuk okozott kórképek pedig nem ritkán súlyos kimenetelűek. A multirezisztens kórokozók (MRK) között felzárkózóban van a VRE, mely fontos intézkedéseket sürget a kórházi infekciókontroll terén. A korábbi években tapasztalt - a kórházunkban is endémiásnak tekinthető - nagyszámú meticillin rezisztens Staphylococcus aureus (MRSA) és Clostridium difficile infekciók (CDI) előfordulása miatt megnőtt a vancomycin felhasználás, ami viszont kedvez a VRE szelektálódásának.}, keywords = {statisztika; ANTIBIOTICUMOK; ENTEROCOCCUS-FERTŐZÉSEK; GYÓGYSZER-RESISTENTIA}, year = {2016}, eissn = {1789-9974}, pages = {26-32}, orcid-numbers = {Nagy, Éva/0000-0001-5988-0530; Barcs, István/0000-0002-6025-4278} }