TY - JOUR AU - Wirth, Roland AU - Maróti, Gergely AU - Lipták, Lídia AU - Mester, Mónika Klára AU - Al Ayoubi, Alaa AU - Pap, Bernadett AU - Madléna, Melinda AU - Minárovits, János AU - Kovács, Kornél Lajos TI - Microbiomes in supragingival biofilms and saliva of adolescents with gingivitis and gingival health JF - ORAL DISEASES J2 - ORAL DIS VL - 28 PY - 2022 IS - 7 SP - 2000 EP - 2014 PG - 15 SN - 1354-523X DO - 10.1111/odi.13883 UR - https://m2.mtmt.hu/api/publication/32020395 ID - 32020395 N1 - Department of Biotechnology, University of Szeged, Szeged, Hungary Institute of Plant Biology, Biological Research Centre, Szeged, Hungary Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Szeged, Hungary Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, University of Szeged, Szeged, Hungary Export Date: 20 October 2021 CODEN: ORDIF Correspondence Address: Kovács, K.L.; Department of Biotechnology, Hungary; email: kovacs.kornel@bio.u-szeged.hu Funding details: Magyar Tudományos Akadémia, MTA Funding details: European Regional Development Fund, ERDF, FK123899, GINOP‐2.3.2‐15‐2016‐00011, PD132145 Funding details: Nemzeti Kutatási Fejlesztési és Innovációs Hivatal, NKFIH Funding details: National Research, Development and Innovation Office Funding text 1: This research was funded by the European Regional Development Fund to a project led by JM grant GINOP‐2.3.2‐15‐2016‐00011. Additional projects GINOP‐2.2.1‐15‐2017‐00081, GINOP‐2.2.1‐15‐2017‐00033, and EFOP‐3.6.2‐16‐2017‐00010 also contributed to this work. RW (PD132145) and GM (FK123899) received support from the National Research, Development and Innovation Office (NKFIH), Hungary. This work was also supported by the János Bolyai Research Scholarship (for GM) of the Hungarian Academy of Sciences. The authors thank the funding agencies for their support. We are indebted to Dr. Márió Gajdács and the unknown Reviewers for critical reading of the manuscript. AB - Background Important alterations exist in the microbiomes of supragingival biofilm and saliva samples from adolescent patients developing induced or spontaneous gingivitis relative to healthy controls. These and the relationships to dental health are not fully understood yet. Subjects and Methods Supragingival biofilm samples (n = 36) were collected from the teeth of 9 adolescents with gingivitis induced by orthodontic appliances, as well as dental plaques (n = 40) from 10 adolescents with spontaneous gingivitis, in addition to similar samples (n = 36) from 9 healthy controls. The bacterial metagenomes were analyzed by 16S rRNA gene amplicon sequencing. Salivary microbiomes of the same persons were characterized by shotgun metagenome sequencing. The data sets were examined using advanced bioinformatics workflows and two reference databases. Results The composition and diversity of bacterial communities did not differ extensively among the three study groups. Nevertheless, the relative abundances of the genera Fusobacterium, Akkermansia, Treponema, and Campylobacter were prominently higher in gingivitis patients versus controls. In contrast, the genera Lautropia, Kingella, Neisseria, Actinomyces, and Rothia were significantly more abundant in controls than in either of the two gingivitis groups. Conclusions The abundance pattern of certain taxa rather than individual strains shows characteristic features of potential diagnostic value. Stringent bioinformatics treatment of the sequencing data is mandatory to avoid unintentional misinterpretations. LA - English DB - MTMT ER - TY - THES AU - Al Ayoubi, Alaa TI - Craniofacial Characteristics of Syrian and Hungarian Adolescents with Class II Division 1 Malocclusion PB - Szegedi Tudományegyetem (SZTE) PY - 2021 SP - 64 DO - 10.14232/phd.10814 UR - https://m2.mtmt.hu/api/publication/32474366 ID - 32474366 LA - English DB - MTMT ER - TY - JOUR AU - Al Ayoubi, Alaa AU - Madléna, Melinda TI - Upper Airway Characteristics in Young Individuals With Class II Division 1 Malocclusion: A Retrospective Inter-Ethnic Cephalometric Comparison JF - JOURNAL OF CRANIOFACIAL SURGERY J2 - J CRANIOFAC SURG VL - 32 PY - 2021 IS - 8 SP - e761 EP - e763 SN - 1049-2275 DO - 10.1097/SCS.0000000000007760 UR - https://m2.mtmt.hu/api/publication/32094793 ID - 32094793 N1 - Export Date: 5 May 2022 AB - This study aimed to compare the upper-airway morphology between strictly matched Syrian (n = 43) and Hungarian (n = 43) adolescents with Class II/1 malocclusion and identify potential associations between upper airway depths and skeletofacial characteristics. Lateral cephalograms were analyzed, and independent-samples tests and correlation coefficients were used for the statistical analyses. The upper-pharyngeal airway was significantly narrower and the soft palate angle was significantly greater in the Syrian adolescents. Alternatively, the hyoid bone was more posteriorly positioned in the Hungarian adolescents when compared to their counterparts. Depths of the upper and middle pharynx were moderately correlated with sagittal and vertical skeletal dimensions only among Syrian subjects. The depth of the lower pharynx was moderately correlated with hyoid bone position, cervical length, and lip-chin-throat angle only among Hungarian subjects. These findings might have potential implications for optimizing the effects of orthognathic/orthodontic treatments on airway structures in these 2 groups. LA - English DB - MTMT ER - TY - JOUR AU - Al Ayoubi, Alaa AU - Dalla Torre, Daniel AU - Madléna, Melinda TI - Craniofacial characteristics of Syrian adolescents with Class II division 1 malocclusion: a retrospective study JF - PEERJ J2 - PEERJ VL - 8 PY - 2020 IS - 7 PG - 18 SN - 2167-8359 DO - 10.7717/peerj.9545 UR - https://m2.mtmt.hu/api/publication/31382840 ID - 31382840 N1 - Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Szeged, Hungary University Clinic of Craniomaxillofacial Surgery, Medical University Innsbruck, Innsbruck, Austria Export Date: 30 September 2020 Correspondence Address: Ayoubi, A.A.; Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of SzegedHungary; email: alaa.alayoubi@outlook.com LA - English DB - MTMT ER - TY - JOUR AU - Al Ayoubi, Alaa AU - Khandan Dezfully, Alireza AU - Madléna, Melinda TI - Dentoskeletal and tooth-size differences between Syrian and Hungarian adolescents with Class II division 1 malocclusion: a retrospective study JF - BMC RESEARCH NOTES J2 - BMC RES NOTES VL - 13 PY - 2020 IS - 1 PG - 7 SN - 1756-0500 DO - 10.1186/s13104-020-05115-0 UR - https://m2.mtmt.hu/api/publication/31382832 ID - 31382832 N1 - Export Date: 30 September 2020 AB - Malocclusion features differ across various populations and ethnicities. At this time, no data are available regarding the dentofacial differences between Syrian and European adolescents with Class II division 1 malocclusion, which is one of the most frequently treated pathologies in orthodontic practice. The present combined cephalometric and tooth-size study aimed to compare the dentoskeletal and tooth-size characteristics of Syrian and Hungarian adolescents with Class II division 1 malocclusion.Class II division 1 malocclusion in Hungarian adolescents was a sagittal discrepancy, while in Syrian adolescents, it was a result of excessive vertical development. Syrian adolescents had a significantly excessive vertical development when compared with Hungarian adolescents, regardless of sex (p < 0.01). Hungarian boys had significantly more protruded maxillae (p < 0.001) and less retruded mandibles (p < 0.01) when compared with Syrian boys, while Hungarian girls had significantly shorter mandibles relative to those of Syrian girls (p < 0.01). Syrian girls had significantly more protrusive lower incisors (p < 0.001), accompanied by significantly larger anterior tooth-size ratios when compared to Hungarian girls (p < 0.001). In conclusion, these findings underscore the importance of considering ethnic differences during orthodontic diagnosis and may have implications for optimizing orthodontic treatments in Syrian and Hungarian adolescents with Class II division 1 malocclusion. LA - English DB - MTMT ER - TY - CONF AU - Al Ayoubi, Alaa AU - Khandan Dezfully, Alireza AU - Madléna, Melinda ED - Szántó, Ildikó ED - Sándor, Balázs ED - Gurdán, Zsuzsanna TI - Comparison of Dentofacial Characteristics between Syrian and Hungarian Adolescents with Class II division 1 malocclusion T2 - VIII. Tóth Pál Vándorgyűlés, MFE Gyermekfogászati és Fogszabályozási Társaság absztraktok PY - 2019 SP - 1 UR - https://m2.mtmt.hu/api/publication/30939215 ID - 30939215 LA - English DB - MTMT ER - TY - CONF AU - Al Ayoubi, Alaa AU - Khandan Dezfully, Alireza AU - Madléna, Melinda TI - Dentofacial Differences between Syrian and Hungarian Adolescents with Class-II/1 Malocclusion T2 - Abstract Book PY - 2019 SP - 150 UR - https://m2.mtmt.hu/api/publication/30939200 ID - 30939200 LA - English DB - MTMT ER - TY - CONF AU - Al Ayoubi, Alaa AU - Khandan Dezfully, Alireza AU - Madléna, Melinda TI - Assessment of dentofacial characteristics in Middle Eastern (Syrian) young orthodontic patients with angle class II division 1 malocclusion T2 - Translational interactive hands-on training and conference on epithelial ion transport including two symposia: "Antibacterial and mucolytic therapy in cystic fibrosis" and "Research in oral cavity – from basic science to clinical use" PY - 2018 SP - 48 UR - https://m2.mtmt.hu/api/publication/30421462 ID - 30421462 LA - English DB - MTMT ER - TY - CHAP AU - Al Ayoubi, Alaa AU - Khandan Dezfully, Alireza AU - Madléna, Melinda ED - Seres, László TI - Assessment of dentofacial characteristics in Middle Eastern (Syrian) young orthodontic patients with Angle Class II division 1 Malocclusion T2 - Magyar Arc-, Állcsont- és Szájsebészeti Társaság XXII. Kongresszusa és Szegedi Fogorvos Találkozó PB - Szegedi Tudományegyetem, Arc-, Állcsont- és Szájsebészeti Klinika CY - Szeged SN - 9789633066072 PY - 2018 SP - 68 EP - 68 PG - 1 UR - https://m2.mtmt.hu/api/publication/3419124 ID - 3419124 LA - English DB - MTMT ER -