@mastersthesis{MTMT:34115930, title = {Development of buccal mucoadhesive polymer films with sodium alginate and cetirizine dihydrochloride in allergy therapy [Allergiaterápiában alkalmazott cetirizin és nátrium-alginát tartalmú bukkális mukoadhezív polimer film fejlesztése]}, url = {https://m2.mtmt.hu/api/publication/34115930}, author = {Pamlényi, Krisztián}, doi = {10.14232/phd.11618}, publisher = {Universití of Szeged}, unique-id = {34115930}, year = {2023} } @{MTMT:34046049, title = {Formulation of buccal films in Parkinson’s disease}, url = {https://m2.mtmt.hu/api/publication/34046049}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Jójártné Laczkovich, Orsolya and Nemes, Dániel and Bácskay, Ildikó and Kristó, Katalin}, booktitle = {V. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science}, doi = {10.14232/syrptbrs.2023.34}, unique-id = {34046049}, year = {2023}, pages = {34-34}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540; Bácskay, Ildikó/0000-0001-8663-2890} } @article{MTMT:34008857, title = {Formulation and characterization of pramipexole containing buccal films for using in Parkinson's disease}, url = {https://m2.mtmt.hu/api/publication/34008857}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Jójártné Laczkovich, Orsolya and Nemes, Dániel and Bácskay, Ildikó and Kristó, Katalin}, doi = {10.1016/j.ejps.2023.106491}, journal-iso = {EUR J PHARM SCI}, journal = {EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES}, volume = {187}, unique-id = {34008857}, issn = {0928-0987}, year = {2023}, eissn = {1879-0720}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540} } @CONFERENCE{MTMT:33550392, title = {Parkinson-kór kezelésében alkalmazható, pramipexolt tartalmazó innovatív bukkális polimer film formulálása és vizsgálata}, url = {https://m2.mtmt.hu/api/publication/33550392}, author = {Pamlényi, Krisztián}, booktitle = {SZTE-GYTK ÚNKP előadóülés}, unique-id = {33550392}, year = {2022}, pages = {10} } @misc{MTMT:33550300, title = {Pramipexolt tartalmazó innovatív bukkális polimer film formulálása és vizsgálata}, url = {https://m2.mtmt.hu/api/publication/33550300}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Bácskay, Ildikó and Nemes, Dániel and Kristó, Katalin}, unique-id = {33550300}, year = {2022}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540} } @{MTMT:33550245, title = {Preparation of buccal films in Parkinson’s Diseasee}, url = {https://m2.mtmt.hu/api/publication/33550245}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Nemes, Dániel and Bácskay, Ildikó and Kristó, Katalin}, booktitle = {9th BBBB International Conference on Pharmaceutical Sciences - Pharma Sciences of Tomorrow: Book of Abstracts}, unique-id = {33550245}, year = {2022}, pages = {105-106}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540} } @article{MTMT:33098362, title = {Controlled Drug Release from Laser Treated Polymeric Carrier}, url = {https://m2.mtmt.hu/api/publication/33098362}, author = {Litauszki, Katalin and Igriczné, É.K. and Pamlényi, Krisztián and Szarka, Györgyi Éva and Kmetty, Ákos and Kovács, Zsolt}, doi = {10.1016/j.xphs.2022.08.018}, journal-iso = {J PHARM SCI}, journal = {JOURNAL OF PHARMACEUTICAL SCIENCES}, volume = {111}, unique-id = {33098362}, issn = {0022-3549}, abstract = {In this study, we present the effect of laser treatment on polymeric poly(lactic acid) drug carrier films. Our goal was to demonstrate the control of the drug-release kinetics of a polymeric carrier as a function of total absorbed laser energy. The controlled drug release kinetic was achieved by modifying the amorphous polymeric carrier's molecular weight via low energy density laser-exposure. According to gel permeation chromatography results, the decrease of molecular weight correlates with an increasing laser-shot number and shows a distinct saturation-like behavior. The dissolution test also suggests the presence of such dependency, as the rate and amount of caffeine released from the sample shows an increasing tendency up to 2000 laser shots. This fact proves that the laser treatment modifies the drug release. The approach presented here may complement other methods used for controlled drug release in various medical and pharmacological applications.}, year = {2022}, eissn = {1520-6017}, pages = {3297-3303}, orcid-numbers = {Litauszki, Katalin/0000-0001-9304-2012; Kmetty, Ákos/0000-0001-6029-3229} } @article{MTMT:33062910, title = {Development and evaluation of bioadhesive buccal films based on sodium alginate for allergy therapy}, url = {https://m2.mtmt.hu/api/publication/33062910}, author = {Pamlényi, Krisztián and Kristó, Katalin and Sovány, Tamás and Regdon, Géza (ifj.)}, doi = {10.1016/j.heliyon.2022.e10364}, journal-iso = {HELIYON}, journal = {HELIYON}, volume = {8}, unique-id = {33062910}, year = {2022}, eissn = {2405-8440}, orcid-numbers = {Sovány, Tamás/0000-0003-3392-7788; Regdon, Géza (ifj.)/0000-0002-6921-3069} } @article{MTMT:33049226, title = {Stability, Permeability and Cytotoxicity of Buccal Films in Allergy Treatment}, url = {https://m2.mtmt.hu/api/publication/33049226}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Nemes, Dániel and Fenyvesi, Ferenc and Bácskay, Ildikó and Kristó, Katalin}, doi = {10.3390/pharmaceutics14081633}, journal-iso = {PHARMACEUTICS}, journal = {PHARMACEUTICS}, volume = {14}, unique-id = {33049226}, issn = {1999-4923}, abstract = {Oral mucoadhesive systems, such as polymer films, are among innovative pharmaceutical products. These systems can be applied in swallowing problems and can also be used in geriatrics and paediatrics. In our earlier work, we successfully formulated buccal mucoadhesive polymer films, which contained cetirizine-hydrochloride (CTZ) as the API. The present study focused on investigating the stability and permeability of the prepared films. The stability of the films was studied with an accelerated stability test. During the stability test, thickness, breaking hardness and in vitro mucoadhesivity were analysed. Furthermore, the interactions were studied with FT-IR spectroscopy, and the changes in the amount of the API were also monitored. Cytotoxicity and cell line permeability studies were carried out on TR 146 buccal cells. Compositions that can preserve more than 85% of the API after 6 months were found. Most of the compositions had a high cell viability of more than 50%. Citric acid (CA) decreased the stability and reduced every physical parameter of the films. However, cell line studies showed that the permeability of the films was enhanced. In our work, we successfully formulated CTZ-containing buccal films with adequate stability, high cell viability and appropriate absorption properties.}, year = {2022}, eissn = {1999-4923}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540; Kristó, Katalin/0000-0003-4127-6831} } @{MTMT:32628560, title = {Stability and permeability properties of sodium alginate buccal films}, url = {https://m2.mtmt.hu/api/publication/32628560}, author = {Pamlényi, Krisztián and Regdon, Géza (ifj.) and Nemes, Dániel and Bácskay, Ildikó and Kristó, Katalin}, booktitle = {IV. Symposium of Young Researchers on Pharmaceutical Technology, Biotechnology and Regulatory Science : book of abstracts}, doi = {10.14232/syrptbrs.2022.26}, unique-id = {32628560}, year = {2022}, pages = {26-26}, orcid-numbers = {Regdon, Géza (ifj.)/0000-0002-6921-3069; Nemes, Dániel/0000-0002-5477-0540} }