@article{MTMT:34677129, title = {Role of CFTR in diabetes‐induced pancreatic ductal fluid and HCO 3 − secretion}, url = {https://m2.mtmt.hu/api/publication/34677129}, author = {Ébert, Attila and Gál, Eleonóra and Tóth, Emese and Szögi, Titanilla and Hegyi, Péter and Venglovecz, Viktória}, doi = {10.1113/JP285702}, journal-iso = {J PHYSIOL-LONDON}, journal = {JOURNAL OF PHYSIOLOGY-LONDON}, volume = {602}, unique-id = {34677129}, issn = {0022-3751}, year = {2024}, eissn = {1469-7793}, pages = {1065-1083}, orcid-numbers = {Szögi, Titanilla/0000-0002-9854-7340; Hegyi, Péter/0000-0003-0399-7259; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:34053506, title = {Importance of MUC17 in the bile-induced pancreatic cancer progression}, url = {https://m2.mtmt.hu/api/publication/34053506}, author = {Gál, Eleonóra and Menyhárt, I and Veréb, Z and Kemény, L and Tiszlavicz, L and Czakó, László and Takács, Tamás and Hegyi, P and Venglovecz, Viktória}, journal-iso = {CENT EUR J GASTRO HEPATOL}, journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE}, volume = {9}, unique-id = {34053506}, year = {2023}, eissn = {2415-9107}, pages = {79-79}, orcid-numbers = {Czakó, László/0000-0002-6331-0802; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:34053481, title = {The role of CFTR in the diabetes-induced pancreatic ductal fluid and HCO3-secretion}, url = {https://m2.mtmt.hu/api/publication/34053481}, author = {Ébert, Attila and Gál, Eleonóra and Tóth, Emese and Hegyi, Péter and Venglovecz, Viktória}, journal-iso = {CENT EUR J GASTRO HEPATOL}, journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE}, volume = {9}, unique-id = {34053481}, year = {2023}, eissn = {2415-9107}, pages = {74-75}, orcid-numbers = {Hegyi, Péter/0000-0003-0399-7259; Venglovecz, Viktória/0000-0002-2316-7247} } @{MTMT:34064907, title = {3D bioprinting of human pancreas cancer model}, url = {https://m2.mtmt.hu/api/publication/34064907}, author = {Parvaneh, Shahram and Lovászi, Borbála and Szűcs, Diána and Monostori, Tamás and Gál, Eleonóra and Venglovecz, Viktória and Kemény, Lajos and Veréb, Zoltán}, booktitle = {Abstract Book of the 1st International Conference of Biomedical Engineering and Innovation}, unique-id = {34064907}, year = {2022}, pages = {48-48}, orcid-numbers = {Venglovecz, Viktória/0000-0002-2316-7247; Veréb, Zoltán/0000-0002-9518-2155} } @article{MTMT:32867137, title = {Calcium imaging in intact mouse acinar cells in acute pancreas tissue slices}, url = {https://m2.mtmt.hu/api/publication/32867137}, author = {Marolt, Urška and Paradiž Leitgeb, Eva and Pohorec, Viljem and Lipovšek, Saška and Venglovecz, Viktória and Gál, Eleonóra and Ébert, Attila and Menyhárt, István and Potrč, Stojan and Gosak, Marko and Dolenšek, Jurij and Stožer, Andraž}, doi = {10.1371/journal.pone.0268644}, journal-iso = {PLOS ONE}, journal = {PLOS ONE}, volume = {17}, unique-id = {32867137}, issn = {1932-6203}, abstract = {The physiology and pathophysiology of the exocrine pancreas are in close connection to changes in intra-cellular Ca2+ concentration. Most of our knowledge is based on in vitro experiments on acinar cells or acini enzymatically isolated from their surroundings, which can alter their structure, physiology, and limit our understanding. Due to these limitations, the acute pancreas tissue slice technique was introduced almost two decades ago as a complementary approach to assess the morphology and physiology of both the endocrine and exocrine pancreas in a more conserved in situ setting. In this study, we extend previous work to functional multicellular calcium imaging on acinar cells in tissue slices. The viability and morphological characteristics of acinar cells within the tissue slice were assessed using the LIVE/DEAD assay, transmission electron microscopy, and immunofluorescence imaging. The main aim of our study was to characterize the responses of acinar cells to stimulation with acetylcholine and compare them with responses to cerulein in pancreatic tissue slices, with special emphasis on inter-cellular and inter-acinar heterogeneity and coupling. To this end, calcium imaging was performed employing confocal microscopy during stimulation with a wide range of acetylcholine concentrations and selected concentrations of cerulein. We show that various calcium oscillation parameters depend monotonically on the stimulus concentration and that the activity is rather well synchronized within acini, but not between acini. The acute pancreas tissue slice represents a viable and reliable experimental approach for the evaluation of both intra- and inter-cellular signaling characteristics of acinar cell calcium dynamics. It can be utilized to assess many cells simultaneously with a high spatiotemporal resolution, thus providing an efficient and high-yield platform for future studies of normal acinar cell biology, pathophysiology, and screening pharmacological substances.}, keywords = {SECRETION; PANCREAS; Mitochondria; VESICLES; cell signaling; calcium imaging; cell staining; Endocrine physiology}, year = {2022}, eissn = {1932-6203}, orcid-numbers = {Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:32843481, title = {The effect of bile on pancreatic cancer, the importance of mucins}, url = {https://m2.mtmt.hu/api/publication/32843481}, author = {Gál, Eleonóra and Veréb, Zoltán and Rakk, Dávid and Szekeres, András and Becskeházi, Eszter and Tiszlavicz, László and Czakó, László and Takács, Tamás and Hegyi, P and Venglovecz, Viktória}, journal-iso = {CENT EUR J GASTRO HEPATOL}, journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE}, volume = {8}, unique-id = {32843481}, year = {2022}, eissn = {2415-9107}, pages = {77-77}, orcid-numbers = {Veréb, Zoltán/0000-0002-9518-2155; Szekeres, András/0000-0003-1651-4623; Tiszlavicz, László/0000-0003-1134-6587; Czakó, László/0000-0002-6331-0802; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:32843357, title = {Mouse esophaegal, organoid cultures are the novel model for studying the epithelial ion transport mechanisms}, url = {https://m2.mtmt.hu/api/publication/32843357}, author = {Korsós, Marietta Margaréta and Bellák, Tamás and Becskeházi, Eszter and Gál, Eleonóra and Veréb, Zoltán and Venglovecz, Viktória}, journal-iso = {CENT EUR J GASTRO HEPATOL}, journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE}, volume = {8}, unique-id = {32843357}, year = {2022}, eissn = {2415-9107}, pages = {85-85}, orcid-numbers = {Veréb, Zoltán/0000-0002-9518-2155; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:32843331, title = {NHE-1 plays a central role in the smoke-induced proliferation in barrett's esophageal cell line}, url = {https://m2.mtmt.hu/api/publication/32843331}, author = {Becskeházi, Eszter and Korsós, Marietta Margaréta and Gál, Eleonóra and Tiszlavicz, László and Hoyk, Z and Deli, M and Köhler, Zoltán Márton and Keller-Pintér, Anikó and Horváth, Attila and Csekő, K and Helyes, Z and Hegyi, Péter and Venglovecz, Viktória}, journal-iso = {CENT EUR J GASTRO HEPATOL}, journal = {CENTRAL EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY / GASZTROENTEROLÓGIAI ÉS HEPATOLÓGIAI SZEMLE}, volume = {8}, unique-id = {32843331}, year = {2022}, eissn = {2415-9107}, pages = {65-65}, orcid-numbers = {Tiszlavicz, László/0000-0003-1134-6587; Köhler, Zoltán Márton/0000-0002-8299-105X; Keller-Pintér, Anikó/0000-0002-4105-8458; Hegyi, Péter/0000-0003-0399-7259; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:32258572, title = {Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett’s Esophageal Cell Line}, url = {https://m2.mtmt.hu/api/publication/32258572}, author = {Becskeházi, Eszter and Korsós, Marietta Margaréta and Gál, Eleonóra and Tiszlavicz, László and Hoyk, Zsófia and Deli, Mária Anna and Köhler, Zoltán Márton and Keller-Pintér, Anikó and Horváth, Attila and Csekő, Kata and Helyes, Zsuzsanna and Hegyi, Péter and Venglovecz, Viktória}, doi = {10.3390/ijms221910581}, journal-iso = {INT J MOL SCI}, journal = {INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES}, volume = {22}, unique-id = {32258572}, issn = {1661-6596}, year = {2021}, eissn = {1422-0067}, orcid-numbers = {Tiszlavicz, László/0000-0003-1134-6587; Deli, Mária Anna/0000-0001-6084-6524; Köhler, Zoltán Márton/0000-0002-8299-105X; Keller-Pintér, Anikó/0000-0002-4105-8458; Hegyi, Péter/0000-0003-0399-7259; Venglovecz, Viktória/0000-0002-2316-7247} } @article{MTMT:32246015, title = {Mechanisms of Post-Pancreatitis Diabetes Mellitus and Cystic Fibrosis-Related Diabetes. A Review of Preclinical Studies}, url = {https://m2.mtmt.hu/api/publication/32246015}, author = {Gál, Eleonóra and Dolenšek, Jurij and Stožer, Andraž and Czakó, László and Ébert, Attila and Venglovecz, Viktória}, doi = {10.3389/fendo.2021.715043}, journal-iso = {FRONT ENDOCRINOL}, journal = {FRONTIERS IN ENDOCRINOLOGY}, volume = {12}, unique-id = {32246015}, issn = {1664-2392}, abstract = {Anatomical proximity and functional correlations between the exocrine and endocrine pancreas warrant reciprocal effects between the two parts. Inflammatory diseases of the exocrine pancreas, such as acute or chronic pancreatitis, or the presence of cystic fibrosis disrupt endocrine function, resulting in diabetes of the exocrine pancreas. Although novel mechanisms are being increasingly identified, the intra- and intercellular pathways regulating exocrine-endocrine interactions are still not fully understood, making the development of new and more effective therapies difficult. Therefore, this review sought to accumulate current knowledge regarding the pathogenesis of diabetes in acute and chronic pancreatitis, as well as cystic fibrosis.}, keywords = {Interaction; cystic fibrosis (CF); acute pancreatitis (AP); Chronic pancreatitis (CP); diabetes of the exocrine pancreas (DEP)}, year = {2021}, eissn = {1664-2392}, pages = {715043-715055}, orcid-numbers = {Czakó, László/0000-0002-6331-0802; Venglovecz, Viktória/0000-0002-2316-7247} }