@article{MTMT:34113096, title = {Evaluation of the routine use of E-cadherin immunohistochemistry in the typing of breast carcinomas : results of a randomized diagnostic study}, url = {https://m2.mtmt.hu/api/publication/34113096}, author = {Cserni, Gábor and Kálmán, Endre and Udvarhelyi, Nóra and Papp, Eszter and Grote, Isabel and Bartels, Stephan and Christgen, Matthias and Kreipe, Hans and Kulka, Janina}, doi = {10.1111/his.15026}, journal-iso = {HISTOPATHOLOGY}, journal = {HISTOPATHOLOGY}, volume = {83}, unique-id = {34113096}, issn = {0309-0167}, abstract = {Invasive lobular carcinoma (ILC) has distinct morphology and association with loss of E-cadherin function. It has special clinical and imaging features, and its proper recognition is important. Following a recent proposal, we tested the value of the routine use of E-cadherin immunohistochemistry (IHC) in recognizing ILC.Five pathologists with experience in breast pathology from four Hungarian institutions histotyped 1001 breast cancers from diagnostic core biopsies or excision specimens randomly assigned to haematoxylin and eosin (HE) diagnosis first, followed by E-cadherin IHC; or to immediate HE and E-cadherin-based diagnosis. Of 524 cases with HE diagnosis, 73(14%) were deemed uncertain. E-cadherin made the initial histological type change in 14/524 cases (2.7%), including three with confident HE-based type allocation. Use of E-cadherin immunostaining was considered useful in 88/477 cases (18%) with immediate dual assessment, and typing uncertainty went down to 5% (25/477 cases), but was not zero. Collective assessment of 171 uncertain, difficult, nonclassical cases resulted in consensus diagnosis in most cases, but 15 cases were still doubtful as concerns their proper histological type. CDH1 gene sequencing was attempted and successful in 13; pathogenic genetic alterations were identified in seven cases.The routine use of E-cadherin IHC decreases the uncertainty in typing and improves the typing accuracy at the cost of potentially redundant additional immunostains. Furthermore, this procedure does not exclude uncertainty due to E-cadherin-positive ILCs, which are occasionally difficult to confidently label as ILC, especially when the growth pattern is not classic.}, keywords = {immunohistochemistry; breast cancer; E-CADHERIN; INVASIVE LOBULAR CARCINOMA; CDH1 mutation}, year = {2023}, eissn = {1365-2559}, pages = {810-821}, orcid-numbers = {Cserni, Gábor/0000-0003-1344-7744; Kulka, Janina/0000-0001-6498-5943} } @misc{MTMT:33623554, title = {A VAB mintavételek feldolgozása. A szeletelt specimen mammográfia indikációi, kivitelezése és nehézségei a mindennapi patológiai gyakorlatban.}, url = {https://m2.mtmt.hu/api/publication/33623554}, author = {Papp, Eszter and Udvarhelyi, Nóra}, unique-id = {33623554}, year = {2023} } @article{MTMT:33024107, title = {Pathological Diagnosis, Work-Up and Reporting of Breast Cancer 1st Central-Eastern European Professional Consensus Statement on Breast Cancer}, url = {https://m2.mtmt.hu/api/publication/33024107}, author = {Cserni, Gábor and Francz, Monika and Járay, Balázs and Kálmán, Endre and Kovács, Ilona and Krenács, Tibor and Tóth, Erika and Udvarhelyi, Nóra and Vass, László and Vörös, András and Krivokuca, Ana and Kajo, Karol and Kajová Macháleková, Katarína and Kulka, Janina}, doi = {10.3389/pore.2022.1610373}, journal-iso = {PATHOL ONCOL RES}, journal = {PATHOLOGY AND ONCOLOGY RESEARCH}, volume = {28}, unique-id = {33024107}, issn = {1219-4956}, abstract = {This text is based on the recommendations accepted by the 4th Hungarian Consensus Conference on Breast Cancer, modified on the basis of the international consultation and conference within the frames of the Central-Eastern European Academy of Oncology. The recommendations cover non-operative, intraoperative and postoperative diagnostics, determination of prognostic and predictive markers and the content of cytology and histology reports. Furthermore, they address some specific issues such as the current status of multigene molecular markers, the role of pathologists in clinical trials and prerequisites for their involvement, and some remarks about the future.}, year = {2022}, eissn = {1532-2807}, orcid-numbers = {Cserni, Gábor/0000-0003-1344-7744; Krenács, Tibor/0000-0001-9164-065X; Tóth, Erika/0000-0003-2054-8447; Vörös, András/0000-0001-6837-0567; Kulka, Janina/0000-0001-6498-5943} } @misc{MTMT:32742788, title = {Emlődaganatok szövettani vizsgálatának eredménye a nemzetközi adatok tükrében az Országos Onkológiai Intézetben}, url = {https://m2.mtmt.hu/api/publication/32742788}, author = {Papp, Eszter and Éles, Klára and Betenbuk, Judit and Udvarhelyi, Nóra}, unique-id = {32742788}, year = {2022} } @article{MTMT:33047856, title = {Corynebacterium caused cystic neutrophilic granulomatous mastitis}, url = {https://m2.mtmt.hu/api/publication/33047856}, author = {Leiner, Maja and Tóth, Erika and Udvarhelyi, Nóra}, journal-iso = {VIRCHOWS ARCH}, journal = {VIRCHOWS ARCHIV}, volume = {479}, unique-id = {33047856}, issn = {0945-6317}, year = {2021}, eissn = {1432-2307}, pages = {S190-S191}, orcid-numbers = {Leiner, Maja/0000-0002-2056-6357; Tóth, Erika/0000-0003-2054-8447} } @article{MTMT:32546673, title = {Mellkasi SMARCA4-deficiens differenciálatlan tumor − esetbemutatás}, url = {https://m2.mtmt.hu/api/publication/32546673}, author = {Székely, Borbála and Papp, Eszter and Somorácz-Kiss, Dóra and Hegyi, Barbara and Udvarhelyi, Nóra and Szentkereszty, Márton and Tóth, Erika and Rubovszky, Gábor}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {65}, unique-id = {32546673}, issn = {0025-0244}, year = {2021}, eissn = {2060-0399}, pages = {54-54}, orcid-numbers = {Hegyi, Barbara/0000-0002-3128-9690; Szentkereszty, Márton/0000-0001-8891-8657; Rubovszky, Gábor/0000-0003-1723-5589} } @article{MTMT:31824193, title = {A Long-Term Retrospective Comparative Study of The Oncological Outcomes of 598 Very Young (≤35 Years) and Young (36-45 Years) Breast Cancer Patients}, url = {https://m2.mtmt.hu/api/publication/31824193}, author = {Újhelyi, Mihály and Szollar, Andras and Polgár, Csaba and Oláh, Edit and Pukancsik, Dávid and Rubovszky, Gábor and Udvarhelyi, Nóra and Kovacs, Tibor and Sávolt, Ákos and Kenessey, István and Mátrai, Zoltán Tamás}, doi = {10.1016/j.ejso.2019.11.006}, journal-iso = {EUR J SURG ONCOL (EJSO)}, journal = {EUROPEAN JOURNAL OF SURGICAL ONCOLOGY}, volume = {46}, unique-id = {31824193}, issn = {0748-7983}, year = {2020}, eissn = {1532-2157}, pages = {e1-e2}, orcid-numbers = {Polgár, Csaba/0000-0001-7245-0762; Rubovszky, Gábor/0000-0003-1723-5589; Kenessey, István/0000-0002-6963-8489} } @article{MTMT:31782993, title = {Az emlőrák patológiai diagnosztikája, feldolgozása és kórszövettani leletezése. Szakmai útmutatás a IV. Emlőrák Konszenzus Konferencia alapján [Pathological diagnosis, work-up and reporting of breast cancer. Recommendations from the 4th Breast Cancer Consensus Conference]}, url = {https://m2.mtmt.hu/api/publication/31782993}, author = {Cserni, Gábor and Francz, Monika and Járay, Balázs and Kálmán, Endre and Kovács, Ilona and Krenács, Tibor and Tóth, Erika and Udvarhelyi, Nóra and Vass, László and Vörös, András and Kulka, Janina}, journal-iso = {MAGYAR ONKOLÓGIA}, journal = {MAGYAR ONKOLÓGIA}, volume = {64}, unique-id = {31782993}, issn = {0025-0244}, abstract = {There have been some relevant changes in the diagnosis and treatment of breast cancer to implement the updating of the 2016 recommendations made during the 3rd national consensus conference on the disease. Following a wide interdisciplinary consultation, the present recommendations have been finalized after their public discussion at the 4th Hungarian Breast Cancer Consensus Conference. The recommendations cover non-operative, intraoperative and postoperative diagnostics, the determination of prognostic and predictive markers and the content of the cytology and histology reports. Furthermore, it touches some special issues such as the current status of multigene molecular markers, the role of pathologists in clinical trials and prerequisites for their involvement, some relevant points about the future. The most important changes include the integration of the TNM 8th edition, the WHO classification of breast tumors 5th edition, the ASCO/CAP HER2 assessment guidelines from 2018, and the Yokohama terminology for cytology reporting; a more detailed text on tumor-infiltrating lymphocytes and size determination after neoadjuvant therapy and a broader discussion of molecular tests.}, year = {2020}, eissn = {2060-0399}, pages = {301-328}, orcid-numbers = {Cserni, Gábor/0000-0003-1344-7744; Krenács, Tibor/0000-0001-9164-065X; Tóth, Erika/0000-0003-2054-8447; Vörös, András/0000-0001-6837-0567; Kulka, Janina/0000-0001-6498-5943} } @article{MTMT:31409182, title = {598 nagyon fiatal (≤35 év) és fiatal (36-45 év) emlőrákos beteg hosszú távú retrospektív klinikopatológiai összehasonlító vizsgálata}, url = {https://m2.mtmt.hu/api/publication/31409182}, author = {Újhelyi, Mihály and Szollár, András and Polgár, Csaba and Oláh, Edit and Pukancsik, Dávid and Rubovszky, Gábor and Udvarhelyi, Nóra and Kovács, Tibor and Sávolt, Ákos and Kenessey, István and Mátrai, Zoltán Tamás}, journal-iso = {MAGYAR SEBÉSZET}, journal = {MAGYAR SEBÉSZET}, volume = {72}, unique-id = {31409182}, issn = {0025-0295}, year = {2019}, eissn = {1789-4301}, pages = {129}, orcid-numbers = {Polgár, Csaba/0000-0001-7245-0762; Rubovszky, Gábor/0000-0003-1723-5589; Sávolt, Ákos/0009-0001-4108-0516; Kenessey, István/0000-0002-6963-8489} } @CONFERENCE{MTMT:31312114, title = {598 nagyon fiatal (≤35 év) és fiatal (36-45 év) emlőrákos beteg hosszú távú retrospektív klinikopatológiai összehasonlító vizsgálata}, url = {https://m2.mtmt.hu/api/publication/31312114}, author = {Újhelyi, Mihály and Szollár, András and Polgár, Csaba and Oláh, Edit and Pukancsik, Dávid and Rubovszky, Gábor and Udvarhelyi, Nóra and Kovács, Tibor and Sávolt, Ákos and Kenessey, István and Mátrai, Zoltán Tamás}, booktitle = {VIII. Szegedi Emlőrák Szimpózium}, unique-id = {31312114}, year = {2019}, pages = {42-42}, orcid-numbers = {Polgár, Csaba/0000-0001-7245-0762; Rubovszky, Gábor/0000-0003-1723-5589; Sávolt, Ákos/0009-0001-4108-0516; Kenessey, István/0000-0002-6963-8489} }